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Volumn 29, Issue 10, 2019, Pages 3033-3046.e4

The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity

Author keywords

antibody dependent cellular cytotoxicity; complement; cytotoxic antibody; Fc receptor; immunoglobulin G; macrophage; natural killer cell; phagocytosis

Indexed keywords

CYTOTOXIC ANTIBODY; FC RECEPTOR; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G2A; MONOCLONAL ANTIBODY;

EID: 85075679874     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2019.10.111     Document Type: Article
Times cited : (15)

References (74)
  • 1
    • 84871105419 scopus 로고    scopus 로고
    • Cutting edge: FcγRIII (CD16) and FcγRI (CD64) are responsible for anti-glycoprotein 75 monoclonal antibody TA99 therapy for experimental metastatic B16 melanoma
    • Albanesi, M., Mancardi, D.A., Macdonald, L.E., Iannascoli, B., Zitvogel, L., Murphy, A.J., Daëron, M., Leusen, J.H., Bruhns, P., Cutting edge: FcγRIII (CD16) and FcγRI (CD64) are responsible for anti-glycoprotein 75 monoclonal antibody TA99 therapy for experimental metastatic B16 melanoma. J. Immunol. 189 (2012), 5513–5517.
    • (2012) J. Immunol. , vol.189 , pp. 5513-5517
    • Albanesi, M.1    Mancardi, D.A.2    Macdonald, L.E.3    Iannascoli, B.4    Zitvogel, L.5    Murphy, A.J.6    Daëron, M.7    Leusen, J.H.8    Bruhns, P.9
  • 4
    • 85017383025 scopus 로고    scopus 로고
    • Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors
    • Arce Vargas, F., Furness, A.J.S., Solomon, I., Joshi, K., Mekkaoui, L., Lesko, M.H., Miranda Rota, E., Dahan, R., Georgiou, A., Sledzinska, A., et al. Melanoma TRACERx Consortium Renal TRACERx Consortium, Lung TRACERx Consortium. Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors. Immunity 46 (2017), 577–586.
    • (2017) Immunity , vol.46 , pp. 577-586
    • Arce Vargas, F.1    Furness, A.J.S.2    Solomon, I.3    Joshi, K.4    Mekkaoui, L.5    Lesko, M.H.6    Miranda Rota, E.7    Dahan, R.8    Georgiou, A.9    Sledzinska, A.10
  • 6
    • 67649404131 scopus 로고    scopus 로고
    • Blood monocytes: development, heterogeneity, and relationship with dendritic cells
    • Auffray, C., Sieweke, M.H., Geissmann, F., Blood monocytes: development, heterogeneity, and relationship with dendritic cells. Annu. Rev. Immunol. 27 (2009), 669–692.
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 669-692
    • Auffray, C.1    Sieweke, M.H.2    Geissmann, F.3
  • 7
    • 0036009179 scopus 로고    scopus 로고
    • FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses
    • Barnes, N., Gavin, A.L., Tan, P.S., Mottram, P., Koentgen, F., Hogarth, P.M., FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses. Immunity 16 (2002), 379–389.
    • (2002) Immunity , vol.16 , pp. 379-389
    • Barnes, N.1    Gavin, A.L.2    Tan, P.S.3    Mottram, P.4    Koentgen, F.5    Hogarth, P.M.6
  • 8
    • 58149162030 scopus 로고    scopus 로고
    • Type II (tositumomab) anti-CD20 monoclonal antibody out performs type I (rituximab-like) reagents in B-cell depletion regardless of complement activation
    • Beers, S.A., Chan, C.H., James, S., French, R.R., Attfield, K.E., Brennan, C.M., Ahuja, A., Shlomchik, M.J., Cragg, M.S., Glennie, M.J., Type II (tositumomab) anti-CD20 monoclonal antibody out performs type I (rituximab-like) reagents in B-cell depletion regardless of complement activation. Blood 112 (2008), 4170–4177.
    • (2008) Blood , vol.112 , pp. 4170-4177
    • Beers, S.A.1    Chan, C.H.2    James, S.3    French, R.R.4    Attfield, K.E.5    Brennan, C.M.6    Ahuja, A.7    Shlomchik, M.J.8    Cragg, M.S.9    Glennie, M.J.10
  • 9
    • 76249096572 scopus 로고    scopus 로고
    • Complement: help or hindrance?
    • Beers, S.A., Cragg, M.S., Glennie, M.J., Complement: help or hindrance?. Blood 114 (2009), 5567–5568.
    • (2009) Blood , vol.114 , pp. 5567-5568
    • Beers, S.A.1    Cragg, M.S.2    Glennie, M.J.3
  • 10
    • 77950331000 scopus 로고    scopus 로고
    • CD20 as a target for therapeutic type I and II monoclonal antibodies
    • Beers, S.A., Chan, C.H., French, R.R., Cragg, M.S., Glennie, M.J., CD20 as a target for therapeutic type I and II monoclonal antibodies. Semin. Hematol. 47 (2010), 107–114.
    • (2010) Semin. Hematol. , vol.47 , pp. 107-114
    • Beers, S.A.1    Chan, C.H.2    French, R.R.3    Cragg, M.S.4    Glennie, M.J.5
  • 12
    • 85065659351 scopus 로고    scopus 로고
    • Understanding Fc Receptor Involvement in Inflammatory Diseases: From Mechanisms to New Therapeutic Tools
    • Ben Mkaddem, S., Benhamou, M., Monteiro, R.C., Understanding Fc Receptor Involvement in Inflammatory Diseases: From Mechanisms to New Therapeutic Tools. Front. Immunol., 10, 2019, 811.
    • (2019) Front. Immunol. , vol.10 , pp. 811
    • Ben Mkaddem, S.1    Benhamou, M.2    Monteiro, R.C.3
  • 13
    • 32944454324 scopus 로고    scopus 로고
    • The high-affinity IgG receptor, FcgammaRI, plays a central role in antibody therapy of experimental melanoma
    • Bevaart, L., Jansen, M.J., van Vugt, M.J., Verbeek, J.S., van de Winkel, J.G., Leusen, J.H., The high-affinity IgG receptor, FcgammaRI, plays a central role in antibody therapy of experimental melanoma. Cancer Res. 66 (2006), 1261–1264.
    • (2006) Cancer Res. , vol.66 , pp. 1261-1264
    • Bevaart, L.1    Jansen, M.J.2    van Vugt, M.J.3    Verbeek, J.S.4    van de Winkel, J.G.5    Leusen, J.H.6
  • 15
    • 84906730343 scopus 로고    scopus 로고
    • How immunoglobulin G antibodies kill target cells: revisiting an old paradigm
    • Biburger, M., Lux, A., Nimmerjahn, F., How immunoglobulin G antibodies kill target cells: revisiting an old paradigm. Adv. Immunol. 124 (2014), 67–94.
    • (2014) Adv. Immunol. , vol.124 , pp. 67-94
    • Biburger, M.1    Lux, A.2    Nimmerjahn, F.3
  • 16
    • 0001321260 scopus 로고
    • Complement fixation on cell surfaces by 19S and 7S antibodies
    • Borsos, T., Rapp, H.J., Complement fixation on cell surfaces by 19S and 7S antibodies. Science 150 (1965), 505–506.
    • (1965) Science , vol.150 , pp. 505-506
    • Borsos, T.1    Rapp, H.J.2
  • 17
    • 84945295233 scopus 로고    scopus 로고
    • Fcγ receptor pathways during active and passive immunization
    • Bournazos, S., Ravetch, J.V., Fcγ receptor pathways during active and passive immunization. Immunol. Rev. 268 (2015), 88–103.
    • (2015) Immunol. Rev. , vol.268 , pp. 88-103
    • Bournazos, S.1    Ravetch, J.V.2
  • 18
    • 84891626935 scopus 로고    scopus 로고
    • Myeloid cells as effector cells for monoclonal antibody therapy of cancer
    • Braster, R., O'Toole, T., van Egmond, M., Myeloid cells as effector cells for monoclonal antibody therapy of cancer. Methods 65 (2014), 28–37.
    • (2014) Methods , vol.65 , pp. 28-37
    • Braster, R.1    O'Toole, T.2    van Egmond, M.3
  • 20
    • 0037399064 scopus 로고    scopus 로고
    • Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease
    • Bruhns, P., Samuelsson, A., Pollard, J.W., Ravetch, J.V., Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease. Immunity 18 (2003), 573–581.
    • (2003) Immunity , vol.18 , pp. 573-581
    • Bruhns, P.1    Samuelsson, A.2    Pollard, J.W.3    Ravetch, J.V.4
  • 21
    • 85056674401 scopus 로고    scopus 로고
    • Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function
    • Buchan, S.L., Dou, L., Remer, M., Booth, S.G., Dunn, S.N., Lai, C., Semmrich, M., Teige, I., Martensson, L., Penfold, C.A., et al. Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function. Immunity 49 (2018), 958–970.e7.
    • (2018) Immunity , vol.49 , pp. 958-970.e7
    • Buchan, S.L.1    Dou, L.2    Remer, M.3    Booth, S.G.4    Dunn, S.N.5    Lai, C.6    Semmrich, M.7    Teige, I.8    Martensson, L.9    Penfold, C.A.10
  • 22
    • 5444259851 scopus 로고    scopus 로고
    • The complement system in regulation of adaptive immunity
    • Carroll, M.C., The complement system in regulation of adaptive immunity. Nat. Immunol. 5 (2004), 981–986.
    • (2004) Nat. Immunol. , vol.5 , pp. 981-986
    • Carroll, M.C.1
  • 24
    • 84859158880 scopus 로고    scopus 로고
    • The CD47-SIRPα pathway in cancer immune evasion and potential therapeutic implications
    • Chao, M.P., Weissman, I.L., Majeti, R., The CD47-SIRPα pathway in cancer immune evasion and potential therapeutic implications. Curr. Opin. Immunol. 24 (2012), 225–232.
    • (2012) Curr. Opin. Immunol. , vol.24 , pp. 225-232
    • Chao, M.P.1    Weissman, I.L.2    Majeti, R.3
  • 25
    • 85053412044 scopus 로고    scopus 로고
    • Natural killer cells and other innate lymphoid cells in cancer
    • Chiossone, L., Dumas, P.Y., Vienne, M., Vivier, E., Natural killer cells and other innate lymphoid cells in cancer. Nat. Rev. Immunol. 18 (2018), 671–688.
    • (2018) Nat. Rev. Immunol. , vol.18 , pp. 671-688
    • Chiossone, L.1    Dumas, P.Y.2    Vienne, M.3    Vivier, E.4
  • 26
    • 1642306050 scopus 로고    scopus 로고
    • Antibody specificity controls in vivo effector mechanisms of anti-CD20 reagents
    • Cragg, M.S., Glennie, M.J., Antibody specificity controls in vivo effector mechanisms of anti-CD20 reagents. Blood 103 (2004), 2738–2743.
    • (2004) Blood , vol.103 , pp. 2738-2743
    • Cragg, M.S.1    Glennie, M.J.2
  • 27
    • 84945272623 scopus 로고    scopus 로고
    • FcγR requirements leading to successful immunotherapy
    • Dahal, L.N., Roghanian, A., Beers, S.A., Cragg, M.S., FcγR requirements leading to successful immunotherapy. Immunol. Rev. 268 (2015), 104–122.
    • (2015) Immunol. Rev. , vol.268 , pp. 104-122
    • Dahal, L.N.1    Roghanian, A.2    Beers, S.A.3    Cragg, M.S.4
  • 28
    • 84930081913 scopus 로고    scopus 로고
    • Differential Fc-Receptor Engagement Drives an Anti-tumor Vaccinal Effect
    • DiLillo, D.J., Ravetch, J.V., Differential Fc-Receptor Engagement Drives an Anti-tumor Vaccinal Effect. Cell 161 (2015), 1035–1045.
    • (2015) Cell , vol.161 , pp. 1035-1045
    • DiLillo, D.J.1    Ravetch, J.V.2
  • 30
    • 85016424015 scopus 로고    scopus 로고
    • Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors
    • Gholamin, S., Mitra, S.S., Feroze, A.H., Liu, J., Kahn, S.A., Zhang, M., Esparza, R., Richard, C., Ramaswamy, V., Remke, M., et al. Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors. Sci. Transl. Med., 9, 2017, eaaf2968.
    • (2017) Sci. Transl. Med. , vol.9 , pp. eaaf2968
    • Gholamin, S.1    Mitra, S.S.2    Feroze, A.H.3    Liu, J.4    Kahn, S.A.5    Zhang, M.6    Esparza, R.7    Richard, C.8    Ramaswamy, V.9    Remke, M.10
  • 31
    • 19944427673 scopus 로고    scopus 로고
    • Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy
    • Gong, Q., Ou, Q., Ye, S., Lee, W.P., Cornelius, J., Diehl, L., Lin, W.Y., Hu, Z., Lu, Y., Chen, Y., et al. Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy. J. Immunol. 174 (2005), 817–826.
    • (2005) J. Immunol. , vol.174 , pp. 817-826
    • Gong, Q.1    Ou, Q.2    Ye, S.3    Lee, W.P.4    Cornelius, J.5    Diehl, L.6    Lin, W.Y.7    Hu, Z.8    Lu, Y.9    Chen, Y.10
  • 32
    • 84945298800 scopus 로고    scopus 로고
    • bIgG time for large eaters: monocytes and macrophages as effector and target cells of antibody-mediated immune activation and repression
    • Gordan, S., Biburger, M., Nimmerjahn, F., bIgG time for large eaters: monocytes and macrophages as effector and target cells of antibody-mediated immune activation and repression. Immunol. Rev. 268 (2015), 52–65.
    • (2015) Immunol. Rev. , vol.268 , pp. 52-65
    • Gordan, S.1    Biburger, M.2    Nimmerjahn, F.3
  • 33
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • Gordon, S., Taylor, P.R., Monocyte and macrophage heterogeneity. Nat. Rev. Immunol. 5 (2005), 953–964.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 36
    • 15444368773 scopus 로고    scopus 로고
    • The peritoneal cavity provides a protective niche for B1 and conventional B lymphocytes during anti-CD20 immunotherapy in mice
    • Hamaguchi, Y., Uchida, J., Cain, D.W., Venturi, G.M., Poe, J.C., Haas, K.M., Tedder, T.F., The peritoneal cavity provides a protective niche for B1 and conventional B lymphocytes during anti-CD20 immunotherapy in mice. J. Immunol. 174 (2005), 4389–4399.
    • (2005) J. Immunol. , vol.174 , pp. 4389-4399
    • Hamaguchi, Y.1    Uchida, J.2    Cain, D.W.3    Venturi, G.M.4    Poe, J.C.5    Haas, K.M.6    Tedder, T.F.7
  • 37
    • 33645053518 scopus 로고    scopus 로고
    • Antibody isotype-specific engagement of Fcgamma receptors regulates B lymphocyte depletion during CD20 immunotherapy
    • Hamaguchi, Y., Xiu, Y., Komura, K., Nimmerjahn, F., Tedder, T.F., Antibody isotype-specific engagement of Fcgamma receptors regulates B lymphocyte depletion during CD20 immunotherapy. J. Exp. Med. 203 (2006), 743–753.
    • (2006) J. Exp. Med. , vol.203 , pp. 743-753
    • Hamaguchi, Y.1    Xiu, Y.2    Komura, K.3    Nimmerjahn, F.4    Tedder, T.F.5
  • 40
    • 84859301570 scopus 로고    scopus 로고
    • Fc receptor-targeted therapies for the treatment of inflammation, cancer and beyond
    • Hogarth, P.M., Pietersz, G.A., Fc receptor-targeted therapies for the treatment of inflammation, cancer and beyond. Nat. Rev. Drug Discov. 11 (2012), 311–331.
    • (2012) Nat. Rev. Drug Discov. , vol.11 , pp. 311-331
    • Hogarth, P.M.1    Pietersz, G.A.2
  • 42
    • 84951291802 scopus 로고    scopus 로고
    • A Monosaccharide Residue Is Sufficient to Maintain Mouse and Human IgG Subclass Activity and Directs IgG Effector Functions to Cellular Fc Receptors
    • Kao, D., Danzer, H., Collin, M., Groß, A., Eichler, J., Stambuk, J., Lauc, G., Lux, A., Nimmerjahn, F., A Monosaccharide Residue Is Sufficient to Maintain Mouse and Human IgG Subclass Activity and Directs IgG Effector Functions to Cellular Fc Receptors. Cell Rep. 13 (2015), 2376–2385.
    • (2015) Cell Rep. , vol.13 , pp. 2376-2385
    • Kao, D.1    Danzer, H.2    Collin, M.3    Groß, A.4    Eichler, J.5    Stambuk, J.6    Lauc, G.7    Lux, A.8    Nimmerjahn, F.9
  • 43
    • 0019835075 scopus 로고
    • A new mouse cell-surface antigen (Ly-m20) controlled by a gene linked to Mls locus and defined by monoclonal antibodies
    • Kimura, S., Tada, N., Nakayama, E., Liu, Y., Hämmerling, U., A new mouse cell-surface antigen (Ly-m20) controlled by a gene linked to Mls locus and defined by monoclonal antibodies. Immunogenetics 14 (1981), 3–14.
    • (1981) Immunogenetics , vol.14 , pp. 3-14
    • Kimura, S.1    Tada, N.2    Nakayama, E.3    Liu, Y.4    Hämmerling, U.5
  • 44
    • 84927571620 scopus 로고    scopus 로고
    • Complement--tapping into new sites and effector systems
    • Kolev, M., Le Friec, G., Kemper, C., Complement--tapping into new sites and effector systems. Nat. Rev. Immunol. 14 (2014), 811–820.
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 811-820
    • Kolev, M.1    Le Friec, G.2    Kemper, C.3
  • 45
    • 0021717580 scopus 로고
    • Establishment of monoclonal anti-Nk-1.1 antibody
    • Koo, G.C., Peppard, J.R., Establishment of monoclonal anti-Nk-1.1 antibody. Hybridoma 3 (1984), 301–303.
    • (1984) Hybridoma , vol.3 , pp. 301-303
    • Koo, G.C.1    Peppard, J.R.2
  • 46
    • 0030699387 scopus 로고    scopus 로고
    • Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor
    • Kurihara, T., Warr, G., Loy, J., Bravo, R., Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor. J. Exp. Med. 186 (1997), 1757–1762.
    • (1997) J. Exp. Med. , vol.186 , pp. 1757-1762
    • Kurihara, T.1    Warr, G.2    Loy, J.3    Bravo, R.4
  • 52
    • 84877074688 scopus 로고    scopus 로고
    • The role of Fc receptors and complement in autoimmunity
    • Mihai, S., Nimmerjahn, F., The role of Fc receptors and complement in autoimmunity. Autoimmun. Rev. 12 (2013), 657–660.
    • (2013) Autoimmun. Rev. , vol.12 , pp. 657-660
    • Mihai, S.1    Nimmerjahn, F.2
  • 53
    • 51649123832 scopus 로고    scopus 로고
    • Lymphoma depletion during CD20 immunotherapy in mice is mediated by macrophage FcgammaRI, FcgammaRIII, and FcgammaRIV
    • Minard-Colin, V., Xiu, Y., Poe, J.C., Horikawa, M., Magro, C.M., Hamaguchi, Y., Haas, K.M., Tedder, T.F., Lymphoma depletion during CD20 immunotherapy in mice is mediated by macrophage FcgammaRI, FcgammaRIII, and FcgammaRIV. Blood 112 (2008), 1205–1213.
    • (2008) Blood , vol.112 , pp. 1205-1213
    • Minard-Colin, V.1    Xiu, Y.2    Poe, J.C.3    Horikawa, M.4    Magro, C.M.5    Hamaguchi, Y.6    Haas, K.M.7    Tedder, T.F.8
  • 55
    • 77957361348 scopus 로고    scopus 로고
    • Development trends for human monoclonal antibody therapeutics
    • Nelson, A.L., Dhimolea, E., Reichert, J.M., Development trends for human monoclonal antibody therapeutics. Nat. Rev. Drug Discov. 9 (2010), 767–774.
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 767-774
    • Nelson, A.L.1    Dhimolea, E.2    Reichert, J.M.3
  • 56
    • 28544449847 scopus 로고    scopus 로고
    • Divergent immunoglobulin g subclass activity through selective Fc receptor binding
    • Nimmerjahn, F., Ravetch, J.V., Divergent immunoglobulin g subclass activity through selective Fc receptor binding. Science 310 (2005), 1510–1512.
    • (2005) Science , vol.310 , pp. 1510-1512
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 57
    • 37549036732 scopus 로고    scopus 로고
    • Fcgamma receptors as regulators of immune responses
    • Nimmerjahn, F., Ravetch, J.V., Fcgamma receptors as regulators of immune responses. Nat. Rev. Immunol. 8 (2008), 34–47.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 34-47
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 58
    • 22544487815 scopus 로고    scopus 로고
    • FcgammaRIV: a novel FcR with distinct IgG subclass specificity
    • Nimmerjahn, F., Bruhns, P., Horiuchi, K., Ravetch, J.V., FcgammaRIV: a novel FcR with distinct IgG subclass specificity. Immunity 23 (2005), 41–51.
    • (2005) Immunity , vol.23 , pp. 41-51
    • Nimmerjahn, F.1    Bruhns, P.2    Horiuchi, K.3    Ravetch, J.V.4
  • 62
    • 77749245817 scopus 로고    scopus 로고
    • In vivo depletion of CD4+FOXP3+ Treg cells by the PC61 anti-CD25 monoclonal antibody is mediated by FcgammaRIII+ phagocytes
    • Setiady, Y.Y., Coccia, J.A., Park, P.U., In vivo depletion of CD4+FOXP3+ Treg cells by the PC61 anti-CD25 monoclonal antibody is mediated by FcgammaRIII+ phagocytes. Eur. J. Immunol. 40 (2010), 780–786.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 780-786
    • Setiady, Y.Y.1    Coccia, J.A.2    Park, P.U.3
  • 64
    • 0028042424 scopus 로고
    • FcR gamma chain deletion results in pleiotrophic effector cell defects
    • Takai, T., Li, M., Sylvestre, D., Clynes, R., Ravetch, J.V., FcR gamma chain deletion results in pleiotrophic effector cell defects. Cell 76 (1994), 519–529.
    • (1994) Cell , vol.76 , pp. 519-529
    • Takai, T.1    Li, M.2    Sylvestre, D.3    Clynes, R.4    Ravetch, J.V.5
  • 65
    • 0030031886 scopus 로고    scopus 로고
    • Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice
    • Takai, T., Ono, M., Hikida, M., Ohmori, H., Ravetch, J.V., Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice. Nature 379 (1996), 346–349.
    • (1996) Nature , vol.379 , pp. 346-349
    • Takai, T.1    Ono, M.2    Hikida, M.3    Ohmori, H.4    Ravetch, J.V.5
  • 66
    • 0028209540 scopus 로고
    • Role of NK1.1+ cells in experimental listeriosis. NK1+ cells are early IFN-gamma producers but impair resistance to Listeria monocytogenes infection
    • Teixeira, H.C., Kaufmann, S.H., Role of NK1.1+ cells in experimental listeriosis. NK1+ cells are early IFN-gamma producers but impair resistance to Listeria monocytogenes infection. J. Immunol. 152 (1994), 1873–1882.
    • (1994) J. Immunol. , vol.152 , pp. 1873-1882
    • Teixeira, H.C.1    Kaufmann, S.H.2
  • 68
    • 3042592452 scopus 로고    scopus 로고
    • The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy
    • Uchida, J., Hamaguchi, Y., Oliver, J.A., Ravetch, J.V., Poe, J.C., Haas, K.M., Tedder, T.F., The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy. J. Exp. Med. 199 (2004), 1659–1669.
    • (2004) J. Exp. Med. , vol.199 , pp. 1659-1669
    • Uchida, J.1    Hamaguchi, Y.2    Oliver, J.A.3    Ravetch, J.V.4    Poe, J.C.5    Haas, K.M.6    Tedder, T.F.7
  • 69
    • 84986305927 scopus 로고    scopus 로고
    • Macrophage-Mediated Trogocytosis Leads to Death of Antibody-Opsonized Tumor Cells
    • Velmurugan, R., Challa, D.K., Ram, S., Ober, R.J., Ward, E.S., Macrophage-Mediated Trogocytosis Leads to Death of Antibody-Opsonized Tumor Cells. Mol. Cancer Ther. 15 (2016), 1879–1889.
    • (2016) Mol. Cancer Ther. , vol.15 , pp. 1879-1889
    • Velmurugan, R.1    Challa, D.K.2    Ram, S.3    Ober, R.J.4    Ward, E.S.5
  • 70
    • 84992445096 scopus 로고    scopus 로고
    • Old dogs-new tricks: immunoregulatory properties of C3 and C5 cleavage fragments
    • Verschoor, A., Karsten, C.M., Broadley, S.P., Laumonnier, Y., Köhl, J., Old dogs-new tricks: immunoregulatory properties of C3 and C5 cleavage fragments. Immunol. Rev. 274 (2016), 112–126.
    • (2016) Immunol. Rev. , vol.274 , pp. 112-126
    • Verschoor, A.1    Karsten, C.M.2    Broadley, S.P.3    Laumonnier, Y.4    Köhl, J.5
  • 72
    • 0029558338 scopus 로고
    • Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity
    • Wessels, M.R., Butko, P., Ma, M., Warren, H.B., Lage, A.L., Carroll, M.C., Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity. Proc. Natl. Acad. Sci. USA 92 (1995), 11490–11494.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11490-11494
    • Wessels, M.R.1    Butko, P.2    Ma, M.3    Warren, H.B.4    Lage, A.L.5    Carroll, M.C.6
  • 74
    • 27244432745 scopus 로고    scopus 로고
    • Immunotherapy using unconjugated CD19 monoclonal antibodies in animal models for B lymphocyte malignancies and autoimmune disease
    • Yazawa, N., Hamaguchi, Y., Poe, J.C., Tedder, T.F., Immunotherapy using unconjugated CD19 monoclonal antibodies in animal models for B lymphocyte malignancies and autoimmune disease. Proc. Natl. Acad. Sci. USA 102 (2005), 15178–15183.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 15178-15183
    • Yazawa, N.1    Hamaguchi, Y.2    Poe, J.C.3    Tedder, T.F.4


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