메뉴 건너뛰기




Volumn 13, Issue JUL, 2019, Pages

Why is there no cure for tinnitus?

Author keywords

Biomarker; Clinical trial design; Cure; Outcome measure; Tinnitus

Indexed keywords

AM 101; AUT 00063; ESKETAMINE; GABAPENTIN; GACYCLIDINE; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PLACEBO; POTASSIUM CHANNEL AFFECTING AGENT; UNCLASSIFIED DRUG;

EID: 85070588333     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2019.00802     Document Type: Article
Times cited : (135)

References (86)
  • 1
    • 84863604876 scopus 로고    scopus 로고
    • Linking the tinnitus questionnaire and the subjective clinical global impression: Which differences are clinically important?
    • Adamchic, I., Tass, P. A., Langguth, B., Hauptmann, C., Koller, M., Schecklmann, M., et al. (2012). Linking the tinnitus questionnaire and the subjective clinical global impression: which differences are clinically important? Health Qual. Life Outcomes. 10:79. doi: 10.1186/1477-7525-10-79
    • (2012) Health Qual. Life Outcomes. , vol.10 , pp. 79
    • Adamchic, I.1    Tass, P.A.2    Langguth, B.3    Hauptmann, C.4    Koller, M.5    Schecklmann, M.6
  • 2
    • 85047226342 scopus 로고    scopus 로고
    • Increased spontaneous firing rates in auditory midbrain following noise exposure are specifically abolished by a Kv3 channel modulator
    • Anderson, L. A., Hesse, L. L., Pilati, N., Bakay, W. M. H., Alvaro, G., Large, C. H., et al. (2018). Increased spontaneous firing rates in auditory midbrain following noise exposure are specifically abolished by a Kv3 channel modulator. Hear Res. 365, 77-89. doi: 10.1016/j.heares.2018.04.012
    • (2018) Hear Res , vol.365 , pp. 77-89
    • Anderson, L.A.1    Hesse, L.L.2    Pilati, N.3    Bakay, W.M.H.4    Alvaro, G.5    Large, C.H.6
  • 3
    • 84887258027 scopus 로고    scopus 로고
    • Tinnitus
    • Baguley, D., McFerran, D., and Hall, D. (2013). Tinnitus. Lancet 382, 1600-1607. doi: 10.1016/S0140-6736(13)60142-7
    • (2013) Lancet , vol.382 , pp. 1600-1607
    • Baguley, D.1    McFerran, D.2    Hall, D.3
  • 4
    • 39049190266 scopus 로고    scopus 로고
    • What progress have we made with tinnitus? The Tonndorf lecture 2005
    • Baguley, D. M. (2006). What progress have we made with tinnitus? The Tonndorf lecture 2005. Acta Otolaryngol. Suppl. 556, 4-8. doi: 10.1080/ 03655230600895218
    • (2006) Acta Otolaryngol. Suppl. , vol.556 , pp. 4-8
    • Baguley, D.M.1
  • 5
    • 85016112738 scopus 로고    scopus 로고
    • Functional auditory disorders
    • Baguley, D. M., Cope, T. E., and McFerran, D. J. (2016). Functional auditory disorders. Handb. Clin. Neurol. 139, 367-378. doi: 10.1016/B978-0-12-801772-2.00032-1
    • (2016) Handb. Clin. Neurol. , vol.139 , pp. 367-378
    • Baguley, D.M.1    Cope, T.E.2    McFerran, D.J.3
  • 6
    • 0034962472 scopus 로고    scopus 로고
    • Assessing tinnitus and prospective tinnitus therapeutics using a psychophysical animal model
    • Bauer, C. A., and Brozoski, T. J. (2001). Assessing tinnitus and prospective tinnitus therapeutics using a psychophysical animal model. J. Assoc. Res. Otolaryngol. 2, 54-64. doi: 10.1007/s101620010030
    • (2001) J. Assoc. Res. Otolaryngol. , vol.2 , pp. 54-64
    • Bauer, C.A.1    Brozoski, T.J.2
  • 7
    • 33745279116 scopus 로고    scopus 로고
    • Effect of gabapentin on the sensation and impact of tinnitus
    • Bauer, C. A., and Brozoski, T. J. (2006). Effect of gabapentin on the sensation and impact of tinnitus. Laryngoscope 116, 675-681. doi: 10.1097/01.MLG. 0000216812.65206.CD
    • (2006) Laryngoscope , vol.116 , pp. 675-681
    • Bauer, C.A.1    Brozoski, T.J.2
  • 9
    • 85065836092 scopus 로고    scopus 로고
    • National institutes of health funding for hearing loss research
    • Epub ahead of print
    • Blustein, J. (2019). National institutes of health funding for hearing loss research. JAMA Otolaryngol. Head Neck Surg. doi: 10.1001/jamaoto.2019.0649 [Epub ahead of print].
    • (2019) JAMA Otolaryngol. Head Neck Surg.
    • Blustein, J.1
  • 10
    • 85063318598 scopus 로고    scopus 로고
    • The search for noise-induced cochlear synaptopathy in humans: Mission impossible?
    • Bramhall, N., Beach, E. F., Epp, B., Le Prell, C. G., Lopez-Poveda, E. A., Plack, C. J., et al. (2019). The search for noise-induced cochlear synaptopathy in humans: mission impossible? Hear Res. 377, 88-103. doi: 10.1016/j.heares.2019.02.016
    • (2019) Hear Res , vol.377 , pp. 88-103
    • Bramhall, N.1    Beach, E.F.2    Epp, B.3    Le Prell, C.G.4    Lopez-Poveda, E.A.5    Plack, C.J.6
  • 11
    • 84887474126 scopus 로고    scopus 로고
    • Hearing loss and tinnitus-are funders and industry listening?
    • Cederroth, C. R., Canlon, B., and Langguth, B. (2013). Hearing loss and tinnitus-are funders and industry listening? Nat. Biotechnol. 31, 972-974. doi: 10.1038/ nbt.2736
    • (2013) Nat. Biotechnol. , vol.31 , pp. 972-974
    • Cederroth, C.R.1    Canlon, B.2    Langguth, B.3
  • 14
    • 84861433951 scopus 로고    scopus 로고
    • Specialised treatment based on cognitive behaviour therapy versus usual care for tinnitus: A randomised controlled trial
    • Cima, R. F., Maes, I. H., Joore, M. A., Scheyen, D. J., El Refaie, A., Baguley, D. M., et al. (2012). Specialised treatment based on cognitive behaviour therapy versus usual care for tinnitus: a randomised controlled trial. Lancet 379, 1951-1959. doi: 10.1016/S0140-6736(12)60469-3
    • (2012) Lancet , vol.379 , pp. 1951-1959
    • Cima, R.F.1    Maes, I.H.2    Joore, M.A.3    Scheyen, D.J.4    El Refaie, A.5    Baguley, D.M.6
  • 15
    • 84958961718 scopus 로고    scopus 로고
    • Repetitive transcranial magnetic stimulation and tinnitus-still a noisy issue
    • Ciminelli, P., Machado, S., and Nardi, A. E. (2016). Repetitive transcranial magnetic stimulation and tinnitus-still a noisy issue. JAMA Otolaryngol. Head Neck Surg. 142, 194-195. doi: 10.1001/jamaoto.2015.2954
    • (2016) JAMA Otolaryngol. Head Neck Surg. , vol.142 , pp. 194-195
    • Ciminelli, P.1    Machado, S.2    Nardi, A.E.3
  • 16
    • 84901946024 scopus 로고    scopus 로고
    • Lessons learned from the fate of AstraZeneca's drug pipeline: A five-dimensional framework
    • Cook, D., Brown, D., Alexander, R., March, R., Morgan, P., Satterthwaite, G., et al. (2014). Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework. Nat. Rev. Drug Discov. 13, 419-431. doi: 10.1038/ nrd4309
    • (2014) Nat. Rev. Drug Discov. , vol.13 , pp. 419-431
    • Cook, D.1    Brown, D.2    Alexander, R.3    March, R.4    Morgan, P.5    Satterthwaite, G.6
  • 17
    • 0001937232 scopus 로고    scopus 로고
    • Epidemiology of tinnitus
    • R. S. Tyler San Diego: Singular
    • Davis, A., and El Rafaie, A. (2000). “Epidemiology of tinnitus,” in Tinnitus Handbook, ed. R. S. Tyler (San Diego: Singular), 1-23.
    • (2000) Tinnitus Handbook , pp. 1-23
    • Davis, A.1    El Rafaie, A.2
  • 18
    • 79955591572 scopus 로고    scopus 로고
    • Efficacy of gabapentin on subjective idiopathic tinnitus: A randomized, double-blind, placebo-controlled trial
    • Dehkordi, M. A., Abolbashari, S., Taheri, R., and Einolghozati, S. (2011). Efficacy of gabapentin on subjective idiopathic tinnitus: a randomized, double-blind, placebo-controlled trial. Ear Nose Throat J. 90, 150-158. doi: 10.1177/ 014556131109000405
    • (2011) Ear Nose Throat J , vol.90 , pp. 150-158
    • Dehkordi, M.A.1    Abolbashari, S.2    Taheri, R.3    Einolghozati, S.4
  • 20
    • 84933671336 scopus 로고    scopus 로고
    • Tinnitus: Animal models and findings in humans
    • Eggermont, J. J., and Roberts, L. E. (2015). Tinnitus: animal models and findings in humans. Cell Tissue Res. 361, 311-336. doi: 10.1007/s00441-014-1992-8
    • (2015) Cell Tissue Res , vol.361 , pp. 311-336
    • Eggermont, J.J.1    Roberts, L.E.2
  • 21
    • 79961021308 scopus 로고    scopus 로고
    • Primary care for tinnitus: Practice and opinion among GPs in England
    • El-Shunnar, S. K., Hoare, D. J., Smith, S., Gander, P. E., Kang, S., Fackrell, K., et al. (2011). Primary care for tinnitus: practice and opinion among GPs in England. J. Eval. Clin. Pract. 17, 684-692. doi: 10.1111/j.1365-2753.2011.01696.x
    • (2011) J. Eval. Clin. Pract. , vol.17 , pp. 684-692
    • El-Shunnar, S.K.1    Hoare, D.J.2    Smith, S.3    Gander, P.E.4    Kang, S.5    Fackrell, K.6
  • 22
    • 79551689000 scopus 로고    scopus 로고
    • Reversing pathological neural activity using targeted plasticity
    • Engineer, N. D., Riley, J. R., Seale, J. D., Vrana, W. A., Shetake, J. A., Sudanagunta, S. P., et al. (2011). Reversing pathological neural activity using targeted plasticity. Nature 470, 101-104. doi: 10.1038/nature09656
    • (2011) Nature , vol.470 , pp. 101-104
    • Engineer, N.D.1    Riley, J.R.2    Seale, J.D.3    Vrana, W.A.4    Shetake, J.A.5    Sudanagunta, S.P.6
  • 23
    • 84947301693 scopus 로고    scopus 로고
    • Psychometric properties of the Tinnitus Functional Index (TFI): Assessment in a UK research volunteer population
    • Fackrell, K., Hall, D. A., Barry, J. G., and Hoare, D. J. (2016). Psychometric properties of the Tinnitus Functional Index (TFI): assessment in a UK research volunteer population. Hear Res. 335, 220-235. doi: 10.1016/j.heares.2015. 09.009
    • (2016) Hear Res , vol.335 , pp. 220-235
    • Fackrell, K.1    Hall, D.A.2    Barry, J.G.3    Hoare, D.J.4
  • 24
    • 85028321010 scopus 로고    scopus 로고
    • Core outcome domains for early phase clinical trials of sound-, psychology-, and pharmacology-based interventions to manage chronic subjective tinnitus in adults: The COMIT'ID study protocol for using a Delphi process and face-to-face meetings to establish consensus
    • Fackrell, K., Smith, H., Colley, V., Thacker, B., Horobin, A., Haider, H. F., et al. (2017). Core outcome domains for early phase clinical trials of sound-, psychology-, and pharmacology-based interventions to manage chronic subjective tinnitus in adults: the COMIT'ID study protocol for using a Delphi process and face-to-face meetings to establish consensus. Trials 18:388. doi: 10.1186/s13063-017-2123-0
    • (2017) Trials , vol.18 , pp. 388
    • Fackrell, K.1    Smith, H.2    Colley, V.3    Thacker, B.4    Horobin, A.5    Haider, H.F.6
  • 26
    • 84930678091 scopus 로고    scopus 로고
    • Gap-prepulse inhibition of the acoustic startle reflex (GPIAS) for tinnitus assessment: Current status and future directions
    • Galazyuk, A., and Hébert, S. (2015). Gap-prepulse inhibition of the acoustic startle reflex (GPIAS) for tinnitus assessment: current status and future directions. Front. Neurol. 6:88. doi: 10.3389/fneur.2015.00088
    • (2015) Front. Neurol. , vol.6 , pp. 88
    • Galazyuk, A.1    Hébert, S.2
  • 27
    • 79959890607 scopus 로고    scopus 로고
    • Tinnitus referral pathways within the national health service in England: A survey of their perceived effectiveness among audiology staff
    • Gander, P. E., Hoare, D. J., Collins, L., Smith, S., and Hall, D. A. (2011). Tinnitus referral pathways within the national health service in England: a survey of their perceived effectiveness among audiology staff. BMC Health Serv. Res. 11:162. doi: 10.1186/1472-6963-11-162
    • (2011) BMC Health Serv. Res. , vol.11 , pp. 162
    • Gander, P.E.1    Hoare, D.J.2    Collins, L.3    Smith, S.4    Hall, D.A.5
  • 28
    • 85064553755 scopus 로고    scopus 로고
    • Alterations in regional homogeneity in patients with unilateral chronic tinnitus
    • 2331216519830237.
    • Gentil, A., Deverdun, J., Menjot, de Champfleur, N., Puel, J. L., Le Bars, E., et al. (2019). Alterations in regional homogeneity in patients with unilateral chronic tinnitus. Trends Hear. 23, 2331216519830237. doi: 10.1177/23312165198 30237
    • (2019) Trends Hear , vol.23
    • Gentil, A.1    Deverdun, J.2    Menjot, D.C.N.3    Puel, J.L.4    Le Bars, E.5
  • 29
    • 85042271270 scopus 로고    scopus 로고
    • Effects of AUT00063, a Kv3.1 channel modulator, on noise-induced hyperactivity in the dorsal cochlear nucleus
    • Glait, L., Fan, W., Stillitano, G., Sandridge, S., Pilati, N., Large, C., et al. (2018). Effects of AUT00063, a Kv3.1 channel modulator, on noise-induced hyperactivity in the dorsal cochlear nucleus. Hear Res. 361, 36-44. doi: 10.1016/ j.heares.2018.01.017
    • (2018) Hear Res , vol.361 , pp. 36-44
    • Glait, L.1    Fan, W.2    Stillitano, G.3    Sandridge, S.4    Pilati, N.5    Large, C.6
  • 32
    • 85013880486 scopus 로고    scopus 로고
    • Short-term effect of gabapentin on subjective tinnitus in acoustic trauma patients
    • Goljanian Tabrizi, A., Safavi Naini, A., and Baradaran, N. (2017). Short-term effect of gabapentin on subjective tinnitus in acoustic trauma patients. Iran. J. Otorhinolaryngol. 29, 95-100.
    • (2017) Iran. J. Otorhinolaryngol. , vol.29 , pp. 95-100
    • Goljanian Tabrizi, A.1    Safavi Naini, A.2    Baradaran, N.3
  • 33
    • 0037868895 scopus 로고    scopus 로고
    • Salicylate induces tinnitus through activation of cochlear NMDA receptors
    • Guitton, M. J., Caston, J., Ruel, J., Johnson, R. M., Pujol, R., and Puel, J. L. (2003). Salicylate induces tinnitus through activation of cochlear NMDA receptors. J. Neurosci. 23, 3944-3952. doi: 10.1523/JNEUROSCI.23-09-03944.2003
    • (2003) J. Neurosci. , vol.23 , pp. 3944-3952
    • Guitton, M.J.1    Caston, J.2    Ruel, J.3    Johnson, R.M.4    Pujol, R.5    Puel, J.L.6
  • 34
    • 84887224930 scopus 로고    scopus 로고
    • Identifying and prioritizing unmet research questions for people with tinnitus: The james lind alliance tinnitus priority setting partnership
    • Hall, D., Mohamad, N., Firkins, L., Fenton, M., and Stockdale, D. (2013). Identifying and prioritizing unmet research questions for people with tinnitus: the james lind alliance tinnitus priority setting partnership. Clin. Investigation. 3, 21-28. doi: 10.4155/cli.12.129
    • (2013) Clin. Investigation. , vol.3 , pp. 21-28
    • Hall, D.1    Mohamad, N.2    Firkins, L.3    Fenton, M.4    Stockdale, D.5
  • 35
    • 84940689040 scopus 로고    scopus 로고
    • Toward a global consensus on outcome measures for clinical trials in tinnitus: Report from the first international meeting of the COMiT initiative, November 14, 2014, Amsterdam, the Netherlands
    • 2331216515580272.
    • Hall, D. A., Haider, H., Kikidis, D., Mielczarek, M., Mazurek, B., Szczepek, A. J., et al. (2015). Toward a global consensus on outcome measures for clinical trials in tinnitus: report from the first international meeting of the COMiT initiative, November 14, 2014, Amsterdam, The Netherlands. Trends Hear. 19, 2331216515580272. doi: 10.1177/2331216515580272
    • (2015) Trends Hear , vol.19
    • Hall, D.A.1    Haider, H.2    Kikidis, D.3    Mielczarek, M.4    Mazurek, B.5    Szczepek, A.J.6
  • 36
    • 85061016419 scopus 로고    scopus 로고
    • One size does not fit all: Developing common standards for outcomes in early-phase clinical trials of sound- Psychology-, and pharmacology-based interventions for chronic subjective tinnitus in adults
    • 2331216518824827.
    • Hall, D. A., Hibbert, A., Smith, H., Haider, H. F., Londero, A., Mazurek, B., et al. (2019a). One size does not fit all: developing common standards for outcomes in early-phase clinical trials of sound- psychology-, and pharmacology-based interventions for chronic subjective tinnitus in adults. Trends Hear. 23, 2331216518824827. doi: 10.1177/2331216518824827
    • (2019) Trends Hear , vol.23
    • Hall, D.A.1    Hibbert, A.2    Smith, H.3    Haider, H.F.4    Londero, A.5    Mazurek, B.6
  • 37
    • 85063643132 scopus 로고    scopus 로고
    • A balanced randomised placebo controlled blinded phase iia multi-centre study to investigate the efficacy and safety of AUT00063 versus placebo in subjective tinnitus: The QUIET-1 trial
    • Hall, D. A., Ray, J., Watson, J., Sharman, A., Hutchison, J., Harris, P., et al. (2019b). A balanced randomised placebo controlled blinded phase iia multi-centre study to investigate the efficacy and safety of AUT00063 versus placebo in subjective tinnitus: the QUIET-1 trial. Hear Res. 377, 153-166. doi: 10.1016/j.heares.2019. 03.018
    • (2019) Hear Res , vol.377 , pp. 153-166
    • Hall, D.A.1    Ray, J.2    Watson, J.3    Sharman, A.4    Hutchison, J.5    Harris, P.6
  • 38
    • 85029699431 scopus 로고    scopus 로고
    • How to choose between measures of tinnitus loudness for clinical research? A report on the reliability and validity of an investigator-administered test and a patient-reported measure using baseline data collected in a phase iia drug trial
    • Hall, D. A., Mehta, R. L., and Fackrell, K. (2017). How to choose between measures of tinnitus loudness for clinical research? A report on the reliability and validity of an investigator-administered test and a patient-reported measure using baseline data collected in a phase iia drug trial. Am. J. Audiol. 26, 338-346. doi: 10.1044/2017_AJA-16-0129
    • (2017) Am. J. Audiol. , vol.26 , pp. 338-346
    • Hall, D.A.1    Mehta, R.L.2    Fackrell, K.3
  • 39
    • 85057532962 scopus 로고    scopus 로고
    • Core Outcome Measures in Tinnitus (COMiT) initiative. The COMiT'ID study: Developing core outcome domains sets for clinical trials of sound-, psychology-, and pharmacology-based interventions for chronic subjective tinnitus in adults
    • 2331216518814384.
    • Hall, D. A., Smith, H., Hibbert, A., Colley, V., Haider, H. F., Horobin, A., et al. (2018). Core Outcome Measures in Tinnitus (COMiT) initiative. The COMiT'ID study: developing core outcome domains sets for clinical trials of sound-, psychology-, and pharmacology-based interventions for chronic subjective tinnitus in adults. Trends Hear. 22, 2331216518814384. doi: 10.1177/ 2331216518814384
    • (2018) Trends Hear , vol.22
    • Hall, D.A.1    Smith, H.2    Hibbert, A.3    Colley, V.4    Haider, H.F.5    Horobin, A.6
  • 40
    • 77049130459 scopus 로고
    • Tinnitus aurium in normally hearing persons
    • Heller, M. F., and Bergman, M. (1953). Tinnitus aurium in normally hearing persons. Ann. Otol. Rhinol. Laryngol. 62, 73-83. doi: 10.1177/ 000348945306200107
    • (1953) Ann. Otol. Rhinol. Laryngol. , vol.62 , pp. 73-83
    • Heller, M.F.1    Bergman, M.2
  • 41
    • 84863295398 scopus 로고    scopus 로고
    • Management of tinnitus in English NHS audiology departments: An evaluation of current practice
    • Hoare, D. J., Gander, P. E., Collins, L., Smith, S., and Hall, D. A. (2012). Management of tinnitus in English NHS audiology departments: an evaluation of current practice. J. Eval. Clin. Pract. 18, 326-334. doi: 10.1111/j.1365-2753. 2010.01566.x
    • (2012) J. Eval. Clin. Pract. , vol.18 , pp. 326-334
    • Hoare, D.J.1    Gander, P.E.2    Collins, L.3    Smith, S.4    Hall, D.A.5
  • 42
    • 85064631771 scopus 로고    scopus 로고
    • Prediction and perception: Insights for (and from) tinnitus
    • Hullfish, J., Sedley, W., and Vanneste, S. (2019). Prediction and perception: insights for (and from) tinnitus. Neurosci. Biobehav. Rev. 102, 1-12. doi: 10.1016/j. neubiorev.2019.04.008
    • (2019) Neurosci. Biobehav. Rev. , vol.102 , pp. 1-12
    • Hullfish, J.1    Sedley, W.2    Vanneste, S.3
  • 43
    • 85046483057 scopus 로고    scopus 로고
    • Expectations for tinnitus treatment and outcomes: A survey study of audiologists and patients
    • Husain, F. T., Gander, P. E., Jansen, J. N., and Shen, S. (2018). Expectations for tinnitus treatment and outcomes: a survey study of audiologists and patients. J. Am. Acad. Audiol. 29, 313-336. doi: 10.3766/jaaa.16154
    • (2018) J. Am. Acad. Audiol. , vol.29 , pp. 313-336
    • Husain, F.T.1    Gander, P.E.2    Jansen, J.N.3    Shen, S.4
  • 44
    • 85059798732 scopus 로고    scopus 로고
    • Objective measures of tinnitus: A systematic review
    • Jackson, R., Vijendren, A., and Phillips, J. (2019). Objective measures of tinnitus: a systematic review. Otol. Neurotol. 40, 154-163. doi: 10.1097/MAO. 0000000000002116
    • (2019) Otol. Neurotol. , vol.40 , pp. 154-163
    • Jackson, R.1    Vijendren, A.2    Phillips, J.3
  • 45
    • 85019542899 scopus 로고    scopus 로고
    • Genetic susceptibility to bilateral tinnitus in a Swedish twin cohort
    • Maas, I. L., Brüggemann, P., Requena, T., Bulla, J., Edvall, N. K., Hjelmborg, J. V. B., et al. (2017). Genetic susceptibility to bilateral tinnitus in a Swedish twin cohort. Genet. Med. 19, 1007-1012. doi: 10.1038/gim.2017.4
    • (2017) Genet. Med. , vol.19 , pp. 1007-1012
    • Maas, I.L.1    Brüggemann, P.2    Requena, T.3    Bulla, J.4    Edvall, N.K.5    Hjelmborg, J.V.B.6
  • 47
    • 85040105825 scopus 로고    scopus 로고
    • Auditory-somatosensory bimodal stimulation desynchronizes brain circuitry to reduce tinnitus in Guinea pigs and humans
    • Marks, K. L., Martel, D. T., Wu, C., Basura, G. J., Roberts, L. E., Schvartz-Leyzac, K. C., et al. (2018). Auditory-somatosensory bimodal stimulation desynchronizes brain circuitry to reduce tinnitus in guinea pigs and humans. Sci. Transl. Med. 10:eaal3175. doi: 10.1126/scitranslmed.aal3175
    • (2018) Sci. Transl. Med. , vol.10
    • Marks, K.L.1    Martel, D.T.2    Wu, C.3    Basura, G.J.4    Roberts, L.E.5    Schvartz-Leyzac, K.C.6
  • 49
    • 78649578071 scopus 로고    scopus 로고
    • The more the worse: The grade of noise-induced hearing loss associates with the severity of tinnitus
    • Mazurek, B., Olze, H., Haupt, H., and Szczepek, A. J. (2010). The more the worse: the grade of noise-induced hearing loss associates with the severity of tinnitus. Int. J. Environ. Res. Public Health. 7, 3071-3079. doi: 10.3390/ijerph7083071
    • (2010) Int. J. Environ. Res. Public Health. , vol.7 , pp. 3071-3079
    • Mazurek, B.1    Olze, H.2    Haupt, H.3    Szczepek, A.J.4
  • 50
    • 84973141720 scopus 로고    scopus 로고
    • A systematic review of the reporting of tinnitus prevalence and severity
    • McCormack, A., Edmondson-Jones, M., Somerset, S., and Hall, D. (2016). A systematic review of the reporting of tinnitus prevalence and severity. Hear Res. 337, 70-79. doi: 10.1016/j.heares.2016.05.009
    • (2016) Hear Res , vol.337 , pp. 70-79
    • McCormack, A.1    Edmondson-Jones, M.2    Somerset, S.3    Hall, D.4
  • 52
    • 85042024742 scopus 로고    scopus 로고
    • Tinnitus services in the United Kingdom: A survey of patient experiences
    • McFerran, D., Hoare, D. J., Carr, S., Ray, J., and Stockdale, D. (2018). Tinnitus services in the United Kingdom: a survey of patient experiences. BMC Health Serv. Res. 18:110. doi: 10.1186/s12913-018-2914-3
    • (2018) BMC Health Serv. Res. , vol.18 , pp. 110
    • McFerran, D.1    Hoare, D.J.2    Carr, S.3    Ray, J.4    Stockdale, D.5
  • 53
    • 0021737106 scopus 로고
    • The perceived severity of tinnitus. Some observations concerning a large population of tinnitus clinic patients
    • Meikle, M. B., Vernon, J., and Johnson, R. M. (1984). The perceived severity of tinnitus. Some observations concerning a large population of tinnitus clinic patients. Otolaryngol. Head Neck Surg. 92, 689-696. doi: 10.1177/ 019459988409200617
    • (1984) Otolaryngol. Head Neck Surg. , vol.92 , pp. 689-696
    • Meikle, M.B.1    Vernon, J.2    Johnson, R.M.3
  • 54
    • 84896547052 scopus 로고    scopus 로고
    • TrkB-mediated protection against circadian sensitivity to noise trauma in the murine cochlea
    • Meltser, I., Cederroth, C. R., Basinou, V., Savelyev, S., Lundkvist, G. S., and Canlon, B. (2014). TrkB-mediated protection against circadian sensitivity to noise trauma in the murine cochlea. Curr. Biol. 24, 658-663. doi: 10.1016/j.cub. 2014.01.047
    • (2014) Curr. Biol. , vol.24 , pp. 658-663
    • Meltser, I.1    Cederroth, C.R.2    Basinou, V.3    Savelyev, S.4    Lundkvist, G.S.5    Canlon, B.6
  • 55
    • 85019911114 scopus 로고    scopus 로고
    • The case for a definitive multisite, randomized clinical trial of repetitive transcranial magnetic stimulation for tinnitus
    • Mennemeier, M., and George, M. (2017). The case for a definitive multisite, randomized clinical trial of repetitive transcranial magnetic stimulation for tinnitus. JAMA Otolaryngol. Head Neck Surg. 143, 441-442. doi: 10.1001/ jamaoto.2016.4055
    • (2017) JAMA Otolaryngol. Head Neck Surg. , vol.143 , pp. 441-442
    • Mennemeier, M.1    George, M.2
  • 56
    • 85027186863 scopus 로고    scopus 로고
    • Auditory brainstem responses in tinnitus: A review of who, how, and what?
    • Milloy, V., Fournier, P., Benoit, D., Noreña, A., and Koravand, A. (2017). Auditory brainstem responses in tinnitus: a review of who, how, and what? Front. Aging Neurosci. 9:237. doi: 10.3389/fnagi.2017.00237
    • (2017) Front. Aging Neurosci. , vol.9 , pp. 237
    • Milloy, V.1    Fournier, P.2    Benoit, D.3    Noreña, A.4    Koravand, A.5
  • 58
    • 84872045101 scopus 로고    scopus 로고
    • Tinnitus-related neural activity: Theories of generation, propagation, and centralization
    • Noreña, A. J., and Farley, B. J. (2013). Tinnitus-related neural activity: theories of generation, propagation, and centralization. Hear Res. 295, 161-171. doi: 10.1016/j.heares.2012.09.010
    • (2013) Hear Res , vol.295 , pp. 161-171
    • Noreña, A.J.1    Farley, B.J.2
  • 59
    • 84956915939 scopus 로고    scopus 로고
    • Transcranial magnetic stimulation for chronic tinnitus
    • Piccirillo, J. F. (2016). Transcranial magnetic stimulation for chronic tinnitus. JAMA 315, 506-507. doi: 10.1001/jama.2016.0075
    • (2016) JAMA , vol.315 , pp. 506-507
    • Piccirillo, J.F.1
  • 61
    • 85027156705 scopus 로고    scopus 로고
    • Does tinnitus depend on time-of-day? An ecological momentary assessment study with the “TrackYourTinnitus” application
    • Probst, T., Pryss, R. C., Langguth, B., Rauschecker, J. P., Schobel, J., Reichert, M., et al. (2017). Does tinnitus depend on time-of-day? An ecological momentary assessment study with the “TrackYourTinnitus” application. Front. Aging Neurosci. 9:253. doi: 10.3389/fnagi.2017.00253
    • (2017) Front. Aging Neurosci. , vol.9 , pp. 253
    • Probst, T.1    Pryss, R.C.2    Langguth, B.3    Rauschecker, J.P.4    Schobel, J.5    Reichert, M.6
  • 62
    • 70349664473 scopus 로고    scopus 로고
    • How-to guide on biomarkers: Biomarker definitions, validation and applications with examples from cardiovascular disease
    • Puntmann, V. O. (2009). How-to guide on biomarkers: biomarker definitions, validation and applications with examples from cardiovascular disease. Postgrad. Med. J. 85, 538-545. doi: 10.1136/pgmj.2008.073759
    • (2009) Postgrad. Med. J. , vol.85 , pp. 538-545
    • Puntmann, V.O.1
  • 64
    • 0034488307 scopus 로고    scopus 로고
    • Survey of the perceived benefits and shortcomings of a specialist tinnitus clinic
    • Sanchez, L., and Stephens, D. (2000). Survey of the perceived benefits and shortcomings of a specialist tinnitus clinic. Audiology 39, 333-339.
    • (2000) Audiology , vol.39 , pp. 333-339
    • Sanchez, L.1    Stephens, D.2
  • 65
    • 31544450569 scopus 로고    scopus 로고
    • Tinnitus in normally hearing patients: Clinical aspects and repercussions
    • Sanchez, T. G., Medeiros, I. R., Levy, C. P., Ramalho, J. D. R., and Bento, R. F. (2005). Tinnitus in normally hearing patients: clinical aspects and repercussions. Braz. J. Otorhinolaryngol. 71, 427-431. doi: 10.1016/s1808-8694(15)31194-0
    • (2005) Braz. J. Otorhinolaryngol. , vol.71 , pp. 427-431
    • Sanchez, T.G.1    Medeiros, I.R.2    Levy, C.P.3    Ramalho, J.D.R.4    Bento, R.F.5
  • 66
    • 84864965083 scopus 로고    scopus 로고
    • Computational models of neurophysiological correlates of tinnitus
    • Schaette, R., and Kempter, R. (2012). Computational models of neurophysiological correlates of tinnitus. Front. Syst. Neurosci. 6:34. doi: 10.3389/fnsys.2012.00034
    • (2012) Front. Syst. Neurosci. , vol.6 , pp. 34
    • Schaette, R.1    Kempter, R.2
  • 67
    • 85040528678 scopus 로고    scopus 로고
    • Innovations in doctoral training and research on tinnitus: The European School on Interdisciplinary Tinnitus research (ESIT) perspective
    • Schlee, W., Hall, D. A., Canlon, B., Cima, R. F. F., de Kleine, E., Hauck, F., et al. (2018). Innovations in doctoral training and research on tinnitus: the European School on Interdisciplinary Tinnitus research (ESIT) perspective. Front. Aging Neurosci. 9:447. doi: 10.3389/fnagi.2017.00447
    • (2018) Front. Aging Neurosci. , vol.9 , pp. 447
    • Schlee, W.1    Hall, D.A.2    Canlon, B.3    Cima, R.F.F.4    De Kleine, E.5    Hauck, F.6
  • 68
    • 85062392858 scopus 로고    scopus 로고
    • Tinnitus: Does gain explain?
    • Sedley, W. (2019). Tinnitus: does gain explain? Neuroscience 407, 213-228. doi: 10.1016/j.neuroscience.2019.01.027
    • (2019) Neuroscience , vol.407 , pp. 213-228
    • Sedley, W.1
  • 69
    • 85000936504 scopus 로고    scopus 로고
    • An integrative tinnitus model based on sensory precision
    • Sedley, W., Friston, K. J., Gander, P. E., Kumar, S., and Griffiths, T. D. (2016). An integrative tinnitus model based on sensory precision. Trends Neurosci. 39, 799-812. doi: 10.1016/j.tins.2016.10.004
    • (2016) Trends Neurosci , vol.39 , pp. 799-812
    • Sedley, W.1    Friston, K.J.2    Gander, P.E.3    Kumar, S.4    Griffiths, T.D.5
  • 70
    • 84927929425 scopus 로고    scopus 로고
    • Selecting appropriate dose regimens for AM-101 in the intratympanic treatment of acute inner ear tinnitus
    • Staecker, H., Maxwell, K. S., Morris, J. R., van de Heyning, P., Morawski, K., and Reintjes, F. (2015). Selecting appropriate dose regimens for AM-101 in the intratympanic treatment of acute inner ear tinnitus. Audiol. Neurootol. 20, 172-182. doi: 10.1159/000369608
    • (2015) Audiol. Neurootol. , vol.20 , pp. 172-182
    • Staecker, H.1    Maxwell, K.S.2    Morris, J.R.3    Van De Heyning, P.4    Morawski, K.5    Reintjes, F.6
  • 71
    • 85028003228 scopus 로고    scopus 로고
    • An economic evaluation of the healthcare cost of tinnitus management in the UK
    • Stockdale, D., McFerran, D., Brazier, P., Pritchard, C., Kay, T., Dowrick, C., et al. (2017). An economic evaluation of the healthcare cost of tinnitus management in the UK. BMC Health Serv. Res. 17:577. doi: 10.1186/s12913-017-2527-2
    • (2017) BMC Health Serv. Res. , vol.17 , pp. 577
    • Stockdale, D.1    McFerran, D.2    Brazier, P.3    Pritchard, C.4    Kay, T.5    Dowrick, C.6
  • 72
    • 85062092804 scopus 로고    scopus 로고
    • Recommendations on collecting and storing samples for genetic studies in hearing and tinnitus research
    • Szczepek, A. J., Frejo, L., Vona, B., Trpchevska, N., Cederroth, C. R., Caria, H., et al. (2019). Recommendations on collecting and storing samples for genetic studies in hearing and tinnitus research. Ear Hear 40, 219-226. doi: 10.1097/ AUD.0000000000000614
    • (2019) Ear Hear , vol.40 , pp. 219-226
    • Szczepek, A.J.1    Frejo, L.2    Vona, B.3    Trpchevska, N.4    Cederroth, C.R.5    Caria, H.6
  • 73
    • 85029645698 scopus 로고    scopus 로고
    • Vagus nerve stimulation paired with tones for the treatment of tinnitus: A prospective randomized double-blind controlled pilot study in humans
    • Tyler, R., Cacace, A., Stocking, C., Tarver, B., Engineer, N., Martin, J., et al. (2017). Vagus nerve stimulation paired with tones for the treatment of tinnitus: a prospective randomized double-blind controlled pilot study in humans. Sci. Rep. 7:11960. doi: 10.1038/s41598-017-12178-w
    • (2017) Sci. Rep. , vol.7 , pp. 11960
    • Tyler, R.1    Cacace, A.2    Stocking, C.3    Tarver, B.4    Engineer, N.5    Martin, J.6
  • 74
    • 84857467224 scopus 로고    scopus 로고
    • Patient preferences and willingness to pay for tinnitus treatments
    • Tyler, R. S. (2012). Patient preferences and willingness to pay for tinnitus treatments. J. Am. Acad. Audiol. 23, 115-125. doi: 10.3766/jaaa. 23.2.6
    • (2012) J. Am. Acad. Audiol. , vol.23 , pp. 115-125
    • Tyler, R.S.1
  • 75
    • 84947474633 scopus 로고    scopus 로고
    • The relevance of the high frequency audiometry in tinnitus patients with normal hearing in conventional pure-tone audiometry
    • Vielsmeier, V., Lehner, A., Strutz, J., Steffens, T., Kreuzer, P. M., Schecklmann, M., et al. (2015). The relevance of the high frequency audiometry in tinnitus patients with normal hearing in conventional pure-tone audiometry. Biomed. Res. Int. 2015:302515. doi: 10.1155/2015/302515
    • (2015) Biomed. Res. Int. , vol.2015 , pp. 302515
    • Vielsmeier, V.1    Lehner, A.2    Strutz, J.3    Steffens, T.4    Kreuzer, P.M.5    Schecklmann, M.6
  • 76
    • 26244437991 scopus 로고    scopus 로고
    • Hearing loss and tinnitus: 250 million people and a US$10 billion potential market
    • Vio, M. M., and Holme, R. H. (2005). Hearing loss and tinnitus: 250 million people and a US$10 billion potential market. Drug Discov. Today. 10, 1263-1265. doi: 10.1016/S1359-6446(05)03594-4
    • (2005) Drug Discov. Today. , vol.10 , pp. 1263-1265
    • Vio, M.M.1    Holme, R.H.2
  • 77
    • 84899926147 scopus 로고    scopus 로고
    • Animal models of subjective tinnitus
    • von der Behrens, W. (2014). Animal models of subjective tinnitus. Neural Plast. 2014:741452. doi: 10.1155/2014/741452
    • (2014) Neural Plast , vol.2014 , pp. 741452
    • Von Der Behrens, W.1
  • 78
    • 85019645713 scopus 로고    scopus 로고
    • Genetics of tinnitus: Still in its infancy
    • Vona, B., Nanda, I., Shehata-Dieler, W., and Haaf, T. (2017). Genetics of tinnitus: still in its infancy. Front. Neurosci. 11:236. doi: 10.3389/fnins.2017. 00236
    • (2017) Front. Neurosci. , vol.11 , pp. 236
    • Vona, B.1    Nanda, I.2    Shehata-Dieler, W.3    Haaf, T.4
  • 79
    • 33750725471 scopus 로고    scopus 로고
    • High-frequency tinnitus without hearing loss does not mean absence of deafferentation
    • Weisz, N., Hartmann, T., Dohrmann, K., Schlee, W., and Norena, A. (2006). High-frequency tinnitus without hearing loss does not mean absence of deafferentation. Hear Res. 222, 108-114. doi: 10.1016/j.heares.2006. 09.003
    • (2006) Hear Res , vol.222 , pp. 108-114
    • Weisz, N.1    Hartmann, T.2    Dohrmann, K.3    Schlee, W.4    Norena, A.5
  • 80
    • 85021978970 scopus 로고    scopus 로고
    • Global hearing health care: New findings and perspectives
    • Wilson, B. S., Tucci, D. L., Merson, M. H., and O'Donoghue, G. M. (2017). Global hearing health care: new findings and perspectives. Lancet 390, 2503-2515. doi: 10.1016/S0140-6736(17)31073-5
    • (2017) Lancet , vol.390 , pp. 2503-2515
    • Wilson, B.S.1    Tucci, D.L.2    Merson, M.H.3    O'Donoghue, G.M.4
  • 81
    • 33846025122 scopus 로고    scopus 로고
    • Treatment of tinnitus with gabapentin: A pilot study
    • Witsell, D. L., Hannley, M. T., Stinnet, S., and Tucci, D. L. (2007). Treatment of tinnitus with gabapentin: a pilot study. Otol. Neurotol. 28, 11-15. doi: 10.1097/ 01.mao.0000235967.53474.93
    • (2007) Otol. Neurotol. , vol.28 , pp. 11-15
    • Witsell, D.L.1    Hannley, M.T.2    Stinnet, S.3    Tucci, D.L.4
  • 82
    • 84932186009 scopus 로고    scopus 로고
    • Tinnitus: Maladaptive auditory-somatosensory plasticity
    • Wu, C., Stefanescu, R. A., Martel, D. T., and Shore, S. E. (2016). Tinnitus: maladaptive auditory-somatosensory plasticity. Hear Res. 334, 20-29. doi: 10. 1016/j.heares.2015.06.005
    • (2016) Hear Res , vol.334 , pp. 20-29
    • Wu, C.1    Stefanescu, R.A.2    Martel, D.T.3    Shore, S.E.4
  • 83
    • 85066474235 scopus 로고    scopus 로고
    • Methodological strategies for ecological momentary assessment to evaluate mood and stress in adult patients using mobile phones: Systematic review
    • Yang, Y. S., Ryu, G. W., and Choi, M. (2019). Methodological strategies for ecological momentary assessment to evaluate mood and stress in adult patients using mobile phones: systematic review. JMIR Mhealth Uhealth 7:e11215. doi: 10.2196/11215
    • (2019) JMIR Mhealth Uhealth , vol.7
    • Yang, Y.S.1    Ryu, G.W.2    Choi, M.3
  • 84
    • 84902689189 scopus 로고    scopus 로고
    • Quality of life in patients with tinnitus and sensorineural hearing loss
    • Zarenoe, R., and Ledin, T. (2014). Quality of life in patients with tinnitus and sensorineural hearing loss. B-ENT 10, 41-51.
    • (2014) B-ENT , vol.10 , pp. 41-51
    • Zarenoe, R.1    Ledin, T.2
  • 85
    • 84856391903 scopus 로고    scopus 로고
    • Tinnitus handicap inventory for evaluating treatment effects: Which changes are clinically relevant?
    • Zeman, F., Koller, M., Figueiredo, R., Aazevedo, A., Rates, M., and Coelho, C. (2011). Tinnitus handicap inventory for evaluating treatment effects: which changes are clinically relevant? Otolaryngol. Head Neck Surg. 145, 282-287. doi: 10.1177/0194599811403882
    • (2011) Otolaryngol. Head Neck Surg. , vol.145 , pp. 282-287
    • Zeman, F.1    Koller, M.2    Figueiredo, R.3    Aazevedo, A.4    Rates, M.5    Coelho, C.6
  • 86
    • 84865847785 scopus 로고    scopus 로고
    • Evidence that memantine reduces chronic tinnitus caused by acoustic trauma in Rats
    • Zheng, Y., McNamara, E., Stiles, L., Darlington, C. L., and Smith, P. F. (2012). Evidence that memantine reduces chronic tinnitus caused by acoustic trauma in Rats. Front. Neurol. 3:127. doi: 10.3389/fneur.2012. 00127
    • (2012) Front. Neurol. , vol.3 , pp. 127
    • Zheng, Y.1    McNamara, E.2    Stiles, L.3    Darlington, C.L.4    Smith, P.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.