Scientific Opinion on the safety and efficacy of formic acid when used as a technological additive for all animal species

EFSA Journal

Volumn 12, Issue 10, 2014, Pages

[No Author Info available]

Author keywords

all animal species; efficacy; formic acid; preservative; safety; silage additive

Indexed keywords

EID: 85070185148     PISSN: None     EISSN: 18314732     Source Type: Journal    
DOI: 10.2903/j.efsa.2014.3827     Document Type: Article

References (15)

1. Canibe N, Miquel N, Miettinen H and Jensen BB, 2001. Effect of addition of formic acid and starter cultures to liquid feed on pH, microflora composition, organic acid production and ammonia production. 15th Forum for Applied Biotechnology, Gent, Belgium, 24–25 September. Mededelingen – Faculteit Landbouwwetenschappen, Rijksuniversiteit Gent, 66/3b, p. 431–434.
2. Canibe N, Hojberg O, Hojsgaard S and Jensen BB, 2005. Feed physical form and formic acid addition to the feed affect the gastrointestinal ecology and growth performance of growing pigs. Journal of Animal Science, 83, 1287–1302.
3. Eckel von B, Kirchgessner M and Roth FX, 1992. Zum einfluss von ameisensaure auf tagliche zunahmen, futteraufnahme, futterverwertung und verdaulichkeit. 1. Mitteilung. Untersuchengen zur nutritive wirksamkeit von organishen sauren in der ferkelaufzucht. Journal of Animal Physiology and Animal Nutrition, 67, 93–100.
4. Eisemann JH and Van Heugten E, 2007. Response of pigs to dietary inclusion of formic acid and ammonium formate. Journal of Animal Science, 85, 1530–1539.
5. EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), 2012. Guidance for the preparation of dossiers for technological additives. EFSA Journal 2012;10(1):2528, 23 pp. doi:10.2903/j.efsa.2012.2528.
6. García V, Catalá-Gregori P, Hernández F, Megías MD and Madrid J, 2007. Effect of formic acid and plant extracts on growth, nutrient digestibility, intestine mucosa morphology and meat yield of broilers. Journal of Applied Poultry Research, 16:555–562.
7. Hernández F, García V, Madrid J, Orengo J, Catala P and Megías MD, 2006. Effect of formic acid on performance, digestibility, intestinal histomorphology and plasma metabolite levels of broiler chicks. British Poultry Science, 47, 50–56.
8. Hungate RE, Smith W, Bauchop T, Yu I and Rabinowitz JC, 1970. Formate as an intermediate in the bovine rumen fermentation. Journal of Bacteriology, 102, 389–397.
9. Hanzlik RP, Fowler SC and Eells JT, 2005. Absorption and elimination of formate following oral administration of calcium formate in female human subjects. Drug Metabolism and Disposition, 33(2), 282–286.
10. JECFA (Joint FAO/WHO Expert Committee on Food Additives), 1974. Toxicological evaluation of some food additives including anticaking agents, antimicrobials, antioxidants, emulsifiers, and thickening agents. FAO Nutrition Meetings Report Series, No 53. Available online: www.inchem.org/documents/jecfa/jecmono/v05je09.htm.
11. JECFA (Joint FAO/WHO Expert Committee on Food Additives), 1998. Safety evaluation of certain food additives and contaminants. Saturated aliphatic acyclic linear primary alcohols, alcohols, aldehydes and acids. WHO Food Additives Series, No 40. Available online: www.inchem.org/documents/jecfa/jecmono/v040je10.htm.
12. Partanen K, 2000. Organic acids-their efficacy and modes of action in pigs. In: Gut environment of pigs. Eds Piva A, Bach Knudsen KE and Lindberg JE. The Nottingham University Press, Nottingham, UK, 201–217.
13. Partanen K, Sijander-Rasi H, Suomi K and Fossi M, 2001. Performance of growing-finishing pigs fed medium- or high-fibre diets supplemented with avilamycin, formic acid or formic-sorbate blend. Livestock Science, 73, 139–152.
14. Vielma J and Lall SP, 1997. Dietary formic acid enhances apparent digestibility of minerals in rainbow trout, Oncorhynchus mykiss (Walbaum). Aquaculture Nutrition, 3, 265–268.
15. Vogt H, Matthes S and Harnisch S, 1981. Der Einfluß organischer Säuren auf die Leistungen von Broilern und Legehennen. Archiv für Geflügelkunde, 45, 221–232.