The role of oxidative stress-mediated apoptosis in the pathogenesis of uric acid nephropathy

Renal Failure

Volumn 41, Issue 1, 2019, Pages 616-622

  Yang, Lijuan ^a   Chang, Baochao ^a   Guo, Yaling ^a   Wu, Xueping ^a   Liu, Lei ^a  

^a BENGBU MEDICAL COLLEGE   (China)

Author keywords

apoptosis; mitochondria; oxidative stress; reduced glutathione; Uric acid nephropathy

Indexed keywords

CASPASE 3; CASPASE 9; CREATININE; GLUTATHIONE; MALONALDEHYDE; PROTEIN BAX; PROTEIN P53; SUPEROXIDE DISMUTASE; URIC ACID; APOPTOSIS REGULATORY PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; IMMUNOBLOTTING; KIDNEY FUNCTION; KIDNEY TISSUE; KIDNEY TUBULE EPITHELIUM; MALE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; RAT; TUMOR SUPPRESSOR GENE; TUNEL ASSAY; URIC ACID BLOOD LEVEL; URIC ACID NEPHROPATHY; ANIMAL; BLOOD; KIDNEY; METABOLISM; MITOCHONDRION; PATHOLOGY; PATHOPHYSIOLOGY; RANDOMIZATION; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; CASPASE 9; CREATININE; GLUTATHIONE; KIDNEY; MALE; MALONDIALDEHYDE; MITOCHONDRIA; OXIDATIVE STRESS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; URIC ACID;

EID: 85069268722     PISSN: 0886022X     EISSN: 15256049     Source Type: Journal    
DOI: 10.1080/0886022X.2019.1633350     Document Type: Article

References (18)

1. Filippatos GS, Ahmed MI, Gladden JD, et al. Hyperuricaemia, chronic kidney disease, and outcomes in heart failure: potential mechanistic insights from epidemiological data. Eur Heart J. 2011;32:712–720.
2. Momoki K, Kataoka H, Moriyama T, et al. Hyperuricemia as a predictive marker for progression of nephrosclerosis: clinical assessment of prognostic factors in biopsy-proven arterial/arteriolar nephrosclerosis. J Atheroscler Thromb. 2017;24:630–642.
3. Cristóbal-García M, García-Arroyo FE, Tapia E, et al. Renal oxidative stress induced by long-term hyperuricemia alters mitochondrial function and maintains systemic hypertension. Oxid Med Cell Longev. 2015;2015:535686.
4. Kim HK, Andreazza AC, Elmi N, et al. Nod-like receptor pyrin containing 3 (NLRP3) in the post-mortem frontal cortex from patients with bipolar disorder: a potential mediator between mitochondria and immune-activation. J Psychiatr Res. 2015;2:43–50.
5. Tao R, Vassilopoulos A, Parisiadou L, et al. Regulation of MnSOD enzymatic activity by Sirt3 connects the mitochondrial acetylome signaling networks to aging and carcinogenesis. Antioxid Redox Signal. 2014;20:1646–1654.
6. Li M, Yang D, Mei L, et al. Screening and characterization of purine nucleoside degrading lactic acid bacteria isolated from Chinese Sauerkraut and evaluation of the serum uric acid lowering effect in hyperuricemic rats. PLoS One. 2014;9:e105577.
7. YongCheng M, Ke Y, Xiaolin Z, et al. Induction of the mitochondria-mediated apoptosis in human esophageal cancer cells by DS2, a newly synthetic diterpenoid analog, is regulated by Bax and caused by generation of reactive oxygen species. Oncotarget. 2016;7:86211–86224.
8. Meng X, Mao Z, Xin L, et al. Baicalein decreases uric acid and prevents hyperuricemic nephropathy in mice. Oncotarget. 2017;8:40305–40317.
9. Magdalena CG, Fernando EG, Edilia T, et al. Renal oxidative stress induced by long-term hyperuricemia alters mitochondrial function and maintains systemic hypertension. Oxid Med Cells Longev. 2015;2015:535686.
10. Ryu ES, Kim MJ, Shin HS, et al. Uric acid-induced phenotypic transition of renal tubular cellss as a novel mechanism of chronic kidney disease. Am J Physiol-Renal Physiol. 2013;304:F471–F480.
11. Giribabu N, Rao PV, Kumar KP, et al. Aqueous extract of phyllanthus niruri leaves displays in vitro antioxidant activity and prevents the elevation of oxidative stress in the kidney of streptozotocin-induced diabetic male rats. Evid Based Complement Alternat Med. 2014;2014:1.
12. Zhen L, Han X, Song X, et al. Overexpressing the Sedum alfredii Cu/Zn superoxide dismutase increased resistance to oxidative stress in transgenic arabidopsis. Front Plant Sci. 2017;8:1010.
13. Park EJ, Choi KS, Yoo YH, et al. Nutlin-3, a small-molecule MDM2 inhibitor, sensitizes Caki cells to TRAIL-induced apoptosis through p53-mediated PUMA upregulation and ROS-mediated DR5 upregulation. Anticancer Drugs. 2013;24:260–269.
14. Tenório J-DR, Santana T, Queiroz S-I-M-L, et al. Apoptosis and cells cycle aberrations in epithelial odontogenic lesions: an evidence by the expression of p53, Bcl-2 and Bax. Med Oral Patol Oral Cir Bucal. 2018;23:e120–e125.
15. Kim EM, Park JK, Hwang S-G, et al. Nuclear and cytoplasmic p53 suppress cell invasion by inhibiting respiratory complex-I activity via Bcl-2 family proteins. Oncotarget. 2014;5:8452–8465.
16. O'Neill KL, Huang K, Zhang J, et al. Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane. Genes Dev. 2016;30:973–988.
17. Moya A, Sakamaki K, Mason BM, et al. Functional conservation of the apoptotic machinery from coral to man: the diverse and complex Bcl-2 and caspase repertoires of Acropora millepora. BMC Genom. 2016;17:62.
18. Shang Y, Siow YL, Isaak CK, et al. Downregulation of glutathione biosynthesis contributes to oxidative stress and liver dysfunction in acute kidney injury. Oxid Med Cell Longev. 2016;2016:9707292.