Tranexamic acid modulates the immune response and reduces postsurgical infection rates

Blood Advances

Volumn 3, Issue 10, 2019, Pages 1598-1609

  Draxler, Dominik F ^a   Yep, Kah ^b   Hanafi, Gryselda ^a   Winton, Anoushka ^b   Daglas, Maria ^a   Ho, Heidi ^a   Sashindranath, Maithili ^a   Wutzlhofer, Lisa M ^b   Forbes, Andrew ^a   Goncalves, Isaac ^a   Tran, Huyen A ^a   Wallace, Sophia ^b   Plebanski, Magdalena ^c   Myles, Paul S ^a,b   Medcalf, Robert L ^a  

^a MONASH UNIVERSITY   (Australia)

^b ALFRED HOSPITAL   (Australia)

^c RMIT UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTIBIOTIC AGENT; CYTOKINE; FIBRIN; PLACEBO; PLASMIN; TRANEXAMIC ACID;

ADULT; ARTICLE; BACTEREMIA; BONE MARROW CELL; CATHETER INFECTION; CELL ACTIVATION; CELL POPULATION; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; CORONARY ARTERY SURGERY; DIABETES MELLITUS; DRUG DOSE REDUCTION; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HEALTHCARE ASSOCIATED INFECTION; HEART SURGERY; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; IMMUNOREGULATION; INFECTION RATE; INFECTIOUS PNEUMONIA; INNATE IMMUNITY; LYMPHOID CELL; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE HEMORRHAGE; POSTOPERATIVE INFECTION; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION; SEPSIS; SOFT TISSUE INFECTION; VOLUNTEER;

EID: 85069086875     PISSN: 24739529     EISSN: 24739537     Source Type: Journal    
DOI: 10.1182/bloodadvances.2019000092     Document Type: Article

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