Handling Oxygenation Targets in the Intensive Care Unit (HOT-ICU)—Protocol for a randomised clinical trial comparing a lower vs a higher oxygenation target in adults with acute hypoxaemic respiratory failure

Acta Anaesthesiologica Scandinavica

Volumn 63, Issue 7, 2019, Pages 956-965

  Schjørring, Olav L ^a,b,c   Perner, Anders ^c,d   Wetterslev, Jørn ^c,d   Lange, Theis ^c,e,f   Keus, Frederik ^g   Laake, Jon H ^h   Okkonen, Marjatta ⁱ   Siegemund, Martin ^j   Morgan, Matthew ^k,l   Thormar, Katrin M ^m   Rasmussen, Bodil S ^a,b,c  

^a AALBORG UNIVERSITY HOSPITAL   (Denmark)

^b AALBORG UNIVERSITY   (Denmark)

^c Department 7831   (Denmark)

^d Rigshospitalet   (Denmark)

^e UNIVERSITY OF COPENHAGEN   (Denmark)

^f PEKING UNIVERSITY   (China)

^g UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^h OSLO UNIVERSITY HOSPITAL   (Norway)

ⁱ HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^j UNIVERSITY HOSPITAL BASEL   (Switzerland)

^k UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

^l CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^m LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

more..

Author keywords

critical illness; hyperoxia; hypoxia; intensive care units; mortality; oxygen inhalation therapy; pragmatic clinical trial; randomised controlled trial; respiratory insufficiency

Indexed keywords

ACUTE HYPOXEMIC RESPIRATORY FAILURE; ACUTE RESPIRATORY FAILURE; ACUTELY ILL PATIENT; ADULT; ADVERSE EVENT; ARTERIAL OXYGEN SATURATION; ARTERIAL OXYGEN TENSION; CLINICAL TRIAL PROTOCOL; COGNITION; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; CRITICALLY ILL PATIENT; FOLLOW UP; HOSPITAL ADMISSION; HOSPITAL MORTALITY; HUMAN; HYPOXEMIA; INTENSIVE CARE UNIT; INTERVENTION STUDY; LENGTH OF STAY; LUNG FUNCTION; MAJOR CLINICAL STUDY; MULTICENTER STUDY; OUTCOME ASSESSMENT; OXYGEN THERAPY; OXYGENATION; PARALLEL DESIGN; PRAGMATIC TRIAL; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; REVIEW; RISK BENEFIT ANALYSIS; RISK REDUCTION; SYSTEMATIC ERROR; AGED; BLOOD; CLINICAL TRIAL; COMPLICATION; FEMALE; HYPOXIA; INTENSIVE CARE; LUNG FUNCTION TEST; MALE; METHODOLOGY; MIDDLE AGED; MORTALITY; ORGANIZATION AND MANAGEMENT; PROCEDURES; RESPIRATORY FAILURE; TREATMENT OUTCOME;

OXYGEN;

ADULT; AGED; CRITICAL CARE; FEMALE; HOSPITAL MORTALITY; HUMANS; HYPOXIA; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; OXYGEN; OXYGEN INHALATION THERAPY; QUALITY OF LIFE; RESEARCH DESIGN; RESPIRATORY FUNCTION TESTS; RESPIRATORY INSUFFICIENCY; TREATMENT OUTCOME;

EID: 85065176528     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/aas.13356     Document Type: Review

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