Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice

Gut

Volumn 69, Issue 1, 2020, Pages 42-51

  Torres, Joana ^a,b   Hu, Jianzhong ^a   Seki, Akihiro ^a   Eisele, Caroline ^a   Nair, Nilendra ^a   Huang, Ruiqi ^a   Tarassishin, Leonid ^a   Jharap, Bindia ^c   Cote Daigneault, Justin ^d   Mao, Qixing ^a,e   Mogno, Ilaria ^a   Britton, Graham J ^a   Uzzan, Mathieu ^a   Chen, Ching Lynn ^a   Kornbluth, Asher ^a   George, James ^a   Legnani, Peter ^a   Maser, Elana ^a   Loudon, Holly ^a   Stone, Joanne ^a   Dubinsky, Marla ^a   Faith, Jeremiah J ^a   Clemente, Jose C ^a   Mehandru, Saurabh ^a   Colombel, Jean Frederic ^a   Peter, Inga ^a   more..

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b Interventional Pulmonology Section   (Portugal)

^c MEANDER MEDICAL CENTER   (Netherlands)

^d CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^e JIANGSU CANCER HOSPITAL   (China)

Author keywords

early life microbiome; inflammatory bowel disease; pregnancy

Indexed keywords

ADAPTIVE IMMUNITY; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; BIFIDOBACTERIUM; CONTROLLED STUDY; CROHN DISEASE; DISEASE ASSOCIATION; DYSBIOSIS; FECES ANALYSIS; FEEDING BEHAVIOR; FEMALE; FETOPLACENTAL UNIT; GAMMAPROTEOBACTERIA; GERMFREE MOUSE; HUMAN; IMMUNOCOMPETENT CELL; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOPATHOLOGY; INFANT; INFLAMMATORY BOWEL DISEASE; INNATE IMMUNITY; INOCULATION; INTESTINE FLORA; MAJOR CLINICAL STUDY; MALE; MATERNAL DISEASE; MEMORY CELL; MICROBIAL DIVERSITY; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; OBSTETRIC DELIVERY; POPULATION ABUNDANCE; PREGNANCY; PREGNANT WOMAN; PRIORITY JOURNAL; PROGENY; PROSPECTIVE STUDY; REGULATORY T LYMPHOCYTE; SPECIES COMPOSITION; TAXONOMY; THIRD TRIMESTER PREGNANCY; ANIMAL; BACTERIUM; CLASSIFICATION; FECAL MICROBIOTA TRANSPLANTATION; FECES; FETOMATERNAL TRANSFUSION; FOLLOW UP; GASTROINTESTINAL TRACT; GERMFREE ANIMAL; IMMUNOLOGY; ISOLATION AND PURIFICATION; MICROBIOLOGY; NEWBORN; PREGNANCY COMPLICATION; PRENATAL EXPOSURE; PROCEDURES;

ADAPTIVE IMMUNITY; ADULT; ANIMALS; BACTERIA; DYSBIOSIS; FECAL MICROBIOTA TRANSPLANTATION; FECES; FEMALE; FOLLOW-UP STUDIES; GASTROINTESTINAL MICROBIOME; GASTROINTESTINAL TRACT; GERM-FREE LIFE; HUMANS; INFANT, NEWBORN; INFLAMMATORY BOWEL DISEASES; MALE; MATERNAL-FETAL EXCHANGE; PREGNANCY; PREGNANCY COMPLICATIONS; PRENATAL EXPOSURE DELAYED EFFECTS; PROSPECTIVE STUDIES;

EID: 85065074049     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2018-317855     Document Type: Article

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