Induction of interleukin-10 expression through Fcα receptor in human monocytes and monocyte-derived dendritic cells: Role of p38 MAPKinase

Immunology and Cell Biology

Volumn 88, Issue 4, 2010, Pages 486-493

  Pilette, Charles ^a   Detry, Bruno ^a   Guisset, Amélie ^a   Gabriels, Julie ^a   Sibille, Yves ^a  

^a CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

Author keywords

Cytokine; IgA; Kinase; Receptor cross linking; Signaling

Indexed keywords

FC ALPHA RECEPTOR; FC RECEPTOR; IMMUNOGLOBULIN A; INTERLEUKIN 10; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCLONAL ANTIBODY; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; ENZYME ACTIVATION; HUMAN; MONOCYTE; PROTEIN EXPRESSION;

BLOTTING, WESTERN; DENDRITIC CELLS; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMANS; IMMUNOGLOBULIN A; INTERLEUKIN-10; MONOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, FC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 77952236284     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2009.120     Document Type: Article

References (43)

1. Allavena P, Piemonti L, Longoni D, Bernasconi S, Stoppacciaro A, Ruco L et al. IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages. Eur J Immunol 1998; 28: 359-369.
2. Goerdt S, Politz O, Schledzewski K, Birk R, Gratchev A, Guillot P et al. Alternative versus classical activation of macrophages. Pathobiology 1999; 67: 222-226.
3. de Waal Malefyt R, Yssel H, Roncarolo MG, Spits H, de Vries JE. Interleukin-1. Curr Opin Immunol 1992; 4: 314-320.
4. Pilette C, Nouri-Aria KT, Jacobson MR, Wilcock LK, Detry B, Walker SM et al. Grass pollen immunotherapy induces an allergen-specific IgA2 antibody response associated with mucosal TGF-beta expression. J Immunol 2007; 178: 4658-4666.
5. Mosser DM. The many faces of macrophage activation. J Leukoc Biol 2003; 73: 209-212.
6. Gerber JS, Mosser DM. Reversing lipopolysaccharide toxicity by ligating the macrophage Fc gamma receptors. J Immunol 2001; 166: 6861-6868.
7. Anderson CF, Gerber JS, Mosser DM. Modulating macrophage function with IgG immune complexes. J Endotoxin Res 2002; 8: 477-481.
8. de Waal Malefyt R, Abrams J, Bennett B, Figdor CG, de Vries JE. Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 1991; 174: 1209-1220.
9. Akbari O, DeKruyff RH, Umetsu DT. Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nat Immunol 2001; 2: 725-731.
10. Brightbill HD, Plevy SE, Modlin RL, Smale ST. A prominent role for Sp1 during lipopolysaccharide-mediated induction of the IL-10 promoter in macrophages. J Immunol 2000; 164: 1940-1951.
11. Tone M, Powell MJ, Tone Y, Thompson SA, Waldmann H. IL-10 gene expression is controlled by the transcription factors Sp1 and Sp3. J Immunol 2000; 165: 286-291.
12. Benkhart EM, Siedlar M, Wedel A, Werner T, Ziegler-Heitbrock HW. Role of Stat3 in lipopolysaccharide-induced IL-10 gene expression. J Immunol 2000; 165: 1612-1617.
13. Liu YW, Tseng HP, Chen LC, Chen BK, Chang WC. Functional cooperation of simian virus 40 promoter factor 1 and CCAAT/enhancer-binding protein beta and delta in lipopolysaccharide-induced gene activation of IL-10 in mouse macrophages. J Immunol 2003; 171: 821-828.
14. Rangan GK, Wang Y, Tay YC, Harris DC. Inhibition of NFkappaB activation with antioxidants is correlated with reduced cytokine transcription in PTC. Am J Physiol 1999; 277: F779-F789.
15. Foey AD, Brennan FM. Conventional protein kinase C and atypical protein kinase Czeta differentially regulate macrophage production of tumour necrosis factor-alpha and interleukin-10. Immunology 2004; 112: 44-53.
16. Wang ZY, Sato H, Kusam S, Sehra S, Toney LM, Dent AL. Regulation of IL-10 gene expression in Th2 cells by Jun proteins. J Immunol 2005; 174: 2098-2105.
17. Cao S, Liu J, Song L, Ma X. The protooncogene c-Maf is an essential transcription factor for IL-10 gene expression in macrophages. J Immunol 2005; 174: 3484-3492.
18. Powell MJ, Thompson SA, Tone Y, Waldmann H, Tone M. Posttranscriptional regulation of IL-10 gene expression through sequences in the 3¢-untranslated region. J Immunol 2000; 165: 292-296.
19. Lucas M, Zhang X, Prasanna V, Mosser DM. ERK activation following macrophage FcgammaR ligation leads to chromatin modifications at the IL-10 locus. J Immunol 2005; 175: 469-477.
20. Pilette C, Durham SR, Vaerman JP, Sibille Y. Mucosal immunity in asthma and chronic obstructive pulmonary disease: a role for immunoglobulin A? Proc Am Thorac Soc 2004; 1: 125-135.
21. Woof JM, Mestecky J. Mucosal immunoglobulins. Immunol Rev 2005; 206: 64-82.
22. Wolf HM, Vogel E, Fischer MB, Rengs H, Schwarz HP, Eibl MM. Inhibition of receptordependent and receptor-independent generation of the respiratory burst in human neutrophils and monocytes by human serum IgA. Pediatr Res 1994; 36: 235-243.
23. Platts-Mills TA, von Maur RK, Ishizaka K, Norman PS, Lichtenstein LM. IgA and IgG anti-ragweed antibodies in nasal secretions. Quantitative measurements of anti- bodies and correlation with inhibition of histamine release. J Clin Invest 1976; 57: 1041-1050.
24. Georgitis JW, Nickelsen JA, Wypych JI, Kane JH, Reisman RE. Local nasal immunotherapy: efficacy of low-dose aqueous ragweed extract. J Allergy Clin Immunol 1985; 75: 496-500.
25. Jutel M, Akdis M, Budak F, Aebischer-Casaulta C, Wrzyszcz M, Blaser K et al. IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy. Eur J Immunol 2003; 33: 1205-1214.
26. Sutterwala FS, Noel GJ, Salgame P, Mosser DM. Reversal of proinflammatory responses by ligating the macrophage Fcgamma receptor type I. J Exp Med 1998; 188: 217-222.
27. Geissmann F, Launay P, Pasquier B, Lepelletier Y, Leborgne M, Lehuen A et al. A subset of human dendritic cells expresses IgA Fc receptor (CD89), which mediates internalization and activation upon cross-linking by IgA complexes. J Immunol 2001; 166: 346-352.
28. Novak N, Bieber T, Katoh N. Engagement of Fc epsilon RI on human monocytes induces the production of IL-10 and prevents their differentiation in dendritic cells. J Immunol 2001; 167: 797-804. (Pubitemid 32660834)
29. Suhrbier A, La Linn M. Suppression of antiviral responses by antibody-dependent enhancement of macrophage infection. Trends Immunol 2003; 24: 165-168.
30. Monteiro RC, Van De Winkel JG. IgA Fc receptors. Annu Rev Immunol 2003; 21: 177-204.
31. Guo X, Gerl RE, Schrader JW. Defining the involvement of p38alpha MAPK in the production of anti- and proinflammatory cytokines using an SB 203580-resistant form of the kinase. J Biol Chem 2003; 278: 22237-22242.
32. Vockerodt M, Haier B, Buttgereit P, Tesch H, Kube D. The Epstein-Barr virus latent membrane protein 1 induces interleukin-10 in Burkitt's lymphoma cells but not in Hodgkin's cells involving the p38/SAPK2 pathway. Virology 2001; 280: 183-198.
33. Williams JA, Pontzer CH, Shacter E. Regulation of macrophage interleukin-6 (IL-6) and IL-10 expression by prostaglandin E2: the role of p38 mitogen-activated protein kinase. J Interferon Cytokine Res 2000; 20: 291-298.
34. Norkina O, Dolganiuc A, Shapiro T, Kodys K, Mandrekar P, Szabo G. Acute alcohol activates STAT3, AP-1, and Sp-1 transcription factors via the family of Src kinases to promote IL-10 production in human monocytes. J Leukoc Biol 2007; 82: 752-762.
35. Herr AB, Ballister ER, Bjorkman PJ. Insights into IgA-mediated immune responses from the crystal structures of human FcalphaRI and its complex with IgA1-Fc. Nature 2003; 423: 614-620.
36. Pasquier B, Launay P, Kanamaru Y, Moura IC, Pfirsch S, Ruffié C et al. Identification of FcalphaRI as an inhibitory receptor that controls inflammation: dual role of FcRgamma ITAM. Immunity 2005; 22: 31-42.
37. Husmann M, Jehnichen P, Jahn B, Schlosshan D, Romahn E, Marx J. A novel SP-1 site in the human interleukin-1 beta promoter confers preferential transcriptional activity in keratinocytes. Eur J Immunol 1996; 26: 3008-3014.
38. Ouadrhiri Y, Pilette C, Monteiro RC, Vaerman JP, Sibille Y. Effect of IgA on respiratory burst and cytokine release by human alveolar macrophages: role of ERK1/2 mitogen-activated protein kinases and NF-kappaB. Am J Respir Cell Mol Biol 2002; 26: 315-332.
39. Ma W, Lim W, Gee K, Aucoin S, Nandan D, Kozlowski M et al. The p38 mitogenactivated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages. J Biol Chem 2001; 276: 13664-13674.
40. Saccani S, Pantano S, Natoli G. p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment. Nat Immunol 2002; 3: 69-75.
41. Chakrabarti A, Sadler AJ, Kar N, Young HA, Silverman RH, Williams BR. Protein kinase R-dependent regulation of interleukin-10 in response to double-stranded RNA. J Biol Chem 2008; 283: 25132-25139.
42. Henry E, Desmet CJ, Garze V, Fievez L, Bedoret D, Heirman C et al. Dendritic cells engineered to express IL-10 induce long-lasting antigen-specific tolerance in experimental asthma. J Immunol 2008; 181: 7230-7242.
43. Macpherson AJ, Gatto D, Sainsbury E, Harriman GR, Hengartner H, Zinkernagel RM. A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria. Science 2000; 288: 2222-2226.