Evolutionary relationship analysis of Middle East respiratory syndrome coronavirus 4a and 4b protein coding sequences

Journal of Veterinary Science

Volumn 20, Issue 2, 2019, Pages

  Kim, Jin Il ^a   Park, Sehee ^a   Bae, Joon Yong ^a   Park, Man Seong ^a  

^a Korea University College of Medicine   (South Korea)

Author keywords

Middle East respiratory syndrome coronavirus; Molecular evolution; Phylogeny; Zoonoses

Indexed keywords

VIRAL PROTEIN; VIRUS RNA;

ANIMAL; CAMEL; CORONAVIRUS INFECTION; GENETICS; HUMAN; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; MOLECULAR EVOLUTION; PHYLOGENY; VETERINARY MEDICINE; VIROLOGY; VIRUS GENE;

ANIMALS; CAMELUS; CORONAVIRUS INFECTIONS; EVOLUTION, MOLECULAR; GENES, VIRAL; HUMANS; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; PHYLOGENY; RNA, VIRAL; VIRAL PROTEINS;

EID: 85064239293     PISSN: 1229845X     EISSN: 1976555X     Source Type: Journal    
DOI: 10.4142/jvs.2019.20.e1     Document Type: Article

References (15)

1. World Health Organization. WHO MERS Global Summary and Assessment of Risk [Internet]. World Health Organization; c2018 [updated August 2018; cited September 10, 2018]. Available from: http://www.who.int/csr/disease/coronavirus_infections/risk-assessment-august-2018.pdf?ua=1
2. World Health Organization. MERS Situation Update [Internet]. World Health Organization; c2018 [updated September 2018; cited September 10, 2018]. Available from: http://applications.emro.who.int/docs/EMROPub_2018_EN_20487.pdf
3. Kim JI, Kim YJ, Lemey P, Lee I, Park S, Bae JY, Kim D, Kim H, Jang SI, Yang JS, Kim H, Kim DW, Nam JG, Kim SS, Kim K, Myun Lee J, Song MK, Song D, Chang J, Hong KJ, Bae YS, Song JW, Lee JS, Park MS. The recent ancestry of Middle East respiratory syndrome coronavirus in Korea has been shaped by recombination. Sci Rep 2016;6:18825
4. van den Brand JM, Smits SL, Haagmans BL. Pathogenesis of Middle East respiratory syndrome coronavirus. J Pathol 2015;235:175-184
5. Kindler E, Jónsdóttir HR, Muth D, Hamming OJ, Hartmann R, Rodriguez R, Geffers R, Fouchier RA, Drosten C, Müller MA, Dijkman R, Thiel V. Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential. MBio 2013;4:e00611-00612
6. Rabouw HH, Langereis MA, Knaap RC, Dalebout TJ, Canton J, Sola I, Enjuanes L, Bredenbeek PJ, Kikkert M, de Groot RJ, van Kuppeveld FJ. Middle East respiratory coronavirus accessory protein 4a inhibits PKR-mediated antiviral stress responses. PLoS Pathog 2016;12:e1005982
7. Siu KL, Yeung ML, Kok KH, Yuen KS, Kew C, Lui PY, Chan CP, Tse H, Woo PC, Yuen KY, Jin DY. Middle East respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response. J Virol 2014;88:4866-4876
8. Canton J, Fehr AR, Fernandez-Delgado R, Gutierrez-Alvarez FJ, Sanchez-Aparicio MT, García-Sastre A, Perlman S, Enjuanes L, Sola I. MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection. PLoS Pathog 2018;14:e1006838
9. Thornbrough JM, Jha BK, Yount B, Goldstein SA, Li Y, Elliott R, Sims AC, Baric RS, Silverman RH, Weiss SR. Middle East respiratory syndrome coronavirus NS4b protein inhibits host RNase L activation. MBio 2016;7:e00258
10. Tripathi S, Balasubramaniam VR, Brown JA, Mena I, Grant A, Bardina SV, Maringer K, Schwarz MC, Maestre AM, Sourisseau M, Albrecht RA, Krammer F, Evans MJ, Fernandez-Sesma A, Lim JK, García-Sastre A. A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses. PLoS Pathog 2017;13:e1006258
11. Turnbull ML, Wise HM, Nicol MQ, Smith N, Dunfee RL, Beard PM, Jagger BW, Ligertwood Y, Hardisty GR, Xiao H, Benton DJ, Coburn AM, Paulo JA, Gygi SP, McCauley JW, Taubenberger JK, Lycett SJ, Weekes MP, Dutia BM, Digard P. Role of the B allele of influenza A virus segment 8 in setting mammalian host range and pathogenicity. J Virol 2016;90:9263-9284
12. Suchard MA, Lemey P, Baele G, Ayres DL, Drummond AJ, Rambaut A. Bayesian phylogenetic and phylodynamic data integration using BEAST 1.10. Virus Evol 2018;4:vey016
13. Posada D. jModelTest: phylogenetic model averaging. Mol Biol Evol 2008;25:1253-1256
14. Aydillo T, Ayllon J, Pavlisin A, Martinez-Romero C, Tripathi S, Mena I, Moreira-Soto A, Vicente-Santos A, Corrales-Aguilar E, Schwemmle M, García-Sastre A. Specific mutations in the PB2 protein of influenza a virus compensate for the lack of efficient interferon antagonism of the NS1 protein of bat influenza A-like viruses. J Virol 2018;92:e02021-17
15. Widagdo W, Raj VS, Schipper D, Kolijn K, van Leenders GJ, Bosch BJ, Bensaid A, Segalés J, Baumgärtner W, Osterhaus AD, Koopmans MP, van den Brand JM, Haagmans BL. Differential expression of the Middle East respiratory syndrome coronavirus receptor in the upper respiratory tracts of humans and dromedary camels. J Virol 2016;90:4838-4842