Enzyme annotation for orphan and novel reactions using knowledge of substrate reactive sites

Proceedings of the National Academy of Sciences of the United States of America

Volumn 116, Issue 15, 2019, Pages 7298-7307

  Hadadi, Noushin ^a   MohammadiPeyhani, Homa ^a   Miskovic, Ljubisa ^a   Seijo, Marianne ^a,b   Hatzimanikatis, Vassily ^a  

^a EPFL   (Switzerland)

^b UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Novel (de novo) reactions; Orphan reactions; Reaction similarity; Reactive site recognition; Sequence similarity

Indexed keywords

ARTICLE; CATALYSIS; ENZYME BINDING; GENOME; PREDICTION; VALIDATION STUDY; BINDING SITE; CHEMISTRY; GENETICS; MOLECULAR GENETICS; PROTEIN DATABASE; SEQUENCE ANALYSIS;

ENZYME;

BINDING SITES; DATABASES, PROTEIN; ENZYMES; MOLECULAR SEQUENCE ANNOTATION; SEQUENCE ANALYSIS, PROTEIN;

EID: 85064110704     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1818877116     Document Type: Article

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