Degradation of endogenous proteins and generation of a null-like phenotype in zebrafish using Trim-Away technology

Genome Biology

Volumn 20, Issue 1, 2019, Pages

  Chen, Xiao ^a   Liu, Mi ^a   Lou, Hongyan ^a   Lu, Yiyi ^a   Zhou, Meng Tao ^a   Ou, Rongying ^a   Xu, Yunsheng ^a   Tang, Kai Fu ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Knockdown; Protein degradation; Trim away; TRIM21

Indexed keywords

PROTEIN ANTIBODY; TRIM21 PROTEIN; TRIPARTITE MOTIF PROTEIN; UNCLASSIFIED DRUG; RIBONUCLEOPROTEIN; SS-A ANTIGEN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FUNCTIONAL MORPHOLOGY; NONHUMAN; NULL ALLELE; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; ZEBRA FISH; ANIMAL; BIOTECHNOLOGY; EVALUATION STUDY; METABOLISM; NONMAMMALIAN EMBRYO; PROCEDURES; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BIOTECHNOLOGY; EMBRYO, NONMAMMALIAN; PROTEOLYSIS; RIBONUCLEOPROTEINS; ZEBRAFISH;

EID: 85060376265     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-019-1624-4     Document Type: Article

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