Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

Nature Genetics

Volumn 51, Issue 2, 2019, Pages 237-244

  Liu, Mengzhen ^a   Jiang, Yu ^b   Wedow, Robbee ^c   Li, Yue ^d,e   Brazel, David M ^c   Chen, Fang ^b   Datta, Gargi ^a   Davila Velderrain, Jose ^d,e   McGuire, Daniel ^b   Tian, Chao ^f   Zhan, Xiaowei ^g,h   Agee, Michelle ^f   Alipanahi, Babak ^f   Auton, Adam ^f   Bell, Robert K ^f   Bryc, Katarzyna ^f   Elson, Sarah L ^f   Fontanillas, Pierre ^f   Furlotte, Nicholas A ^f   Hinds, David A ^f   Hromatka, Bethann S ^f   Huber, Karen E ^f   Kleinman, Aaron ^f   Litterman, Nadia K ^f   McIntyre, Matthew H ^f   Mountain, Joanna L ^f   Northover, Carrie A M ^f   Sathirapongsasuti, J Fah ^f   Sazonova, Olga V ^f   Shelton, Janie F ^f   Shringarpure, Suyash ^f   Tung, Joyce Y ^f   Vacic, Vladimir ^f   Wilson, Catherine H ^f   Pitts, Steven J ^f   Mitchell, Amy ^au   Skogholt, Anne Heidi ^m   Winsvold, Bendik Slagsvold ^au   Sivertsen, Børge ^m,az,ba   Stordal, Eystein ^m,bb   Morken, Gunnar ^m,bc   Kallestad, Håvard ^m,bc   Heuch, Ingrid ^ba   Zwart, John Anker ^au,bd   Fjukstad, Katrine Kveli ^m,be   Pedersen, Linda M ^au   Gabrielsen, Maiken Elvestad ^m   Johnsen, Marianne Bakke ^au,bd   Skrove, Marit ^m   Indredavik, Marit Sæbø ^m   Drange, Ole Kristian ^m,bc   Bjerkeset, Ottar ^m,bf   Børte, Sigrid ^au,bd   Stensland, Synne Øien ^au,bg   Choquet, Hélène ⁱ   Docherty, Anna R ^j,k   Faul, Jessica D ^l   Foerster, Johanna R ^l   Fritsche, Lars G ^l   Gordon, Scott D ⁿ   Haessler, Jeffrey ^o   Hottenga, Jouke Jan ^p   Huang, Hongyan ^q   Jang, Seon Kyeong ^a   Jansen, Philip R ^p,r   Ling, Yueh ^b,c   Mägi, Reedik ^s   Matoba, Nana ^t   McMahon, George ^u   Mulas, Antonella ^v   Orrù, Valeria ^v   Palviainen, Teemu ^w   Pandit, Anita ^l   Reginsson, Gunnar W ^x   Smith, Jennifer A ^l   Taylor, Amy E ^u   Turman, Constance ^q   Willemsen, Gonneke ^p   Young, Hannah ^a   Young, Kendra A ^y   Zajac, Gregory J M ^l   Zhao, Wei ^l   Zhou, Wei ^z   Bjornsdottir, Gyda ^x   Boardman, Jason D ^c   Boehnke, Michael ^l   Boomsma, Dorret I ^p   Chen, Chu ^o   Cucca, Francesco ^v   Davies, Gareth E ^aa   Eaton, Charles B ^ab   Ehringer, Marissa A ^c   Esko, Tõnu ^e,s   Fiorillo, Edoardo ^v   Gillespie, Nathan A ^j,n   Gudbjartsson, Daniel F ^x,ac   Haller, Toomas ^s   Harris, Kathleen Mullan ^ad,ae   Heath, Andrew C ^af   Hewitt, John K ^c   Hickie, Ian B ^ag   Hokanson, John E ^y   Hopfer, Christian J ^c,ah   Hunter, David J ^q,ai   Iacono, William G ^a   Johnson, Eric O ^aj   Kamatani, Yoichiro ^t   Kardia, Sharon L R ^l   Keller, Matthew C ^c   Kellis, Manolis ^d,e   Kooperberg, Charles ^o   Kraft, Peter ^q   Krauter, Kenneth S ^c   Laakso, Markku ^ak,al   Lind, Penelope A ⁿ   Loukola, Anu ^w   Lutz, Sharon M ^y   Madden, Pamela A F ^af   Martin, Nicholas G ⁿ   McGue, Matt ^a   McQueen, Matthew B ^c   Medland, Sarah E ⁿ   Metspalu, Andres ^s   Mohlke, Karen L ^am   Nielsen, Jonas B ^z   Okada, Yukinori ^t,an   Peters, Ulrike ^o,ao   Polderman, Tinca J C ^p   Posthuma, Danielle ^p,ap   Reiner, Alexander P ^o,ao   Rice, John P ^af   Rimm, Eric ^q   Rose, Richard J ^aq   Runarsdottir, Valgerdur ^ar   Stallings, Michael C ^c   Stančáková, Alena ^ak   Stefansson, Hreinn ^x   Thai, Khanh K ⁱ   Tindle, Hilary A ^as   Tyrfingsson, Thorarinn ^ar   Wall, Tamara L ^at   Weir, David R ^l   Weisner, Constance ⁱ   Whitfield, John B ⁿ   Yin, Jie ⁱ   Zuccolo, Luisa ^u,av   Bierut, Laura J ^af   Hveem, Kristian ^m,aw   Lee, James J ^a   Munafò, Marcus R ^av   Saccone, Nancy L ^af   Willer, Cristen J ^z   Cornelis, Marilyn C ^ax   David, Sean P ^ay   Jorgenson, Eric ⁱ   Kaprio, Jaakko ^w   Stitzel, Jerry A ^c   Stefansson, Kari ^x,ac   Thorgeirsson, Thorgeir E ^x   Abecasis, Gonçalo ^l   Liu, Dajiang J ^b   Vrieze, Scott ^a   more..

^a UNIVERSITY OF MINNESOTA   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^f 23andMe Inc ^*  (United States)

^g UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^h UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

ⁱ DIVISION OF RESEARCH   (United States)

^j VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^k UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^l UNIVERSITY OF MICHIGAN   (United States)

^m NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

ⁿ QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^o USA   (United States)

^p VU UNIVERSITY AMSTERDAM   (Netherlands)

^q HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^r ERASMUS MEDICAL CENTER   (Netherlands)

^s UNIVERSITY OF TARTU   (Estonia)

^t Institute of Physical and Chemical Research   (Japan)

^u UNIVERSITY OF BRISTOL   (United Kingdom)

^v Milan Unit   (Italy)

^w UNIVERSITY OF HELSINKI   (Finland)

^x DECODE GENETICS   (Iceland)

^y UNIVERSITY OF COLORADO   (United States)

^z UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^aa Avera Health   (United States)

^ab BROWN UNIVERSITY   (United States)

^ac UNIVERSITY OF ICELAND   (Iceland)

^ad UNIVERSITY OF NORTH CAROLINA   (United States)

^ae UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL   (United States)

^af WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^ag UNIVERSITY OF SYDNEY   (Australia)

^ah UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^ai UNIVERSITY OF OXFORD   (United Kingdom)

^aj RTI INTERNATIONAL   (United States)

^ak UNIVERSITY OF EASTERN FINLAND   (Finland)

^al KUOPIO UNIVERSITY HOSPITAL   (Finland)

^am UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^an OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^ao UNIVERSITY OF WASHINGTON   (United States)

^ap VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^aq INDIANA UNIVERSITY   (United States)

^ar Vogur Hospital   (Iceland)

^as VANDERBILT UNIVERSITY   (United States)

^at UNIVERSITY OF CALIFORNIA   (United States)

^au OSLO UNIVERSITY HOSPITAL   (Norway)

^av UNIVERSITY OF BRISTOL   (United Kingdom)

^aw North Trondelag Hospital Trust   (Norway)

^ax NORTHWESTERN UNIVERSITY   (United States)

^ay STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^az NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^ba Levanger Hospital ^*  (Norway)

^bb Nord Trøndelag Hospital Trust   (Norway)

^bc TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^bd UNIVERSITY OF OSLO   (Norway)

^be Levanger Hospital   (Norway)

^bf NORD UNIVERSITY   (Norway)

^bg Norwegian Centre for Violence and Traumatic Stress Studies   (Norway)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; DOPAMINE RECEPTOR; NICOTINIC RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; NICOTINE;

ALCOHOL CONSUMPTION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC CORRELATION; GENETIC RISK; GENETIC VARIABILITY; GLUTAMATERGIC SYNAPSE; HUMAN; LETTER; NEUROTRANSMISSION; PLEIOTROPY; PRIORITY JOURNAL; SMOKING CESSATION; TOBACCO USE; DRINKING BEHAVIOR; FEMALE; GENETIC VARIATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; MALE; META ANALYSIS; MIDDLE AGED; PHENOTYPE; PROCEDURES; RISK; SMOKING; TOBACCO; TOBACCO DEPENDENCE; ADH1B GENE; ALGORITHM; CONFIDENCE INTERVAL; ENTPD6 GENE; EPIGENETICS; GENE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; GENE SET ANALYSIS; GENETIC ASSOCIATION STUDY; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HERITABILITY; META ANALYSIS (TOPIC); PHYLOGENY; PREDICTION; PREVALENCE; QUALITY CONTROL; REV3L GENE; RHOT2 GENE; SAMPLE SIZE; SINGLE NUCLEOTIDE POLYMORPHISM;

ALCOHOL DRINKING; FEMALE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; RISK; SMOKING; TOBACCO; TOBACCO USE DISORDER;

EID: 85060099159     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/s41588-018-0307-5     Document Type: Letter

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