Tranexamic acid in total joint arthroplasty: The endorsed clinical practice guides of the American Association of Hip and Knee Surgeons, American Society of Regional Anesthesia and Pain Medicine, American Academy of Orthopaedic Surgeons, Hip Society, and Knee Society

Regional Anesthesia and Pain Medicine

Volumn 44, Issue 1, 2019, Pages 7-11

  Fillingham, Yale A ^a   Ramkumar, Dipak B ^b   Jevsevar, David S ^b   Yates, Adolph J ^c   Bini, Stefano A ^d   Clarke, Henry D ^e   Schemitsch, Emil ^f   Johnson, Rebecca L ^g   Memtsoudis, Stavros G ^h   Sayeed, Siraj A ⁱ   Sah, Alexander P ^j   Della Valle, Craig J ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

^c UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e MAYO CLINIC   (United States)

^f UNIVERSITY OF TORONTO   (Canada)

^g MAYO CLINIC   (United States)

^h HOSPITAL FOR SPECIAL SURGERY   (United States)

ⁱ South Texas Bone and Joint Institute   (United States)

^j Dearborn Sah Institute for Joint Restoration   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO; TRANEXAMIC ACID; ANTIFIBRINOLYTIC AGENT;

ARTICLE; COMPARATIVE STUDY; EVIDENCE BASED PRACTICE; HIGH RISK PATIENT; HUMAN; NETWORK META-ANALYSIS; ORTHOPEDIC SURGEON; PEER REVIEW; PERIOPERATIVE PERIOD; POSTOPERATIVE PAIN; PRACTICE GUIDELINE; PRIORITY JOURNAL; REGIONAL ANESTHESIA; TOTAL HIP REPLACEMENT; TOTAL KNEE ARTHROPLASTY; ARTHROPLASTY; EPIDEMIOLOGY; HIP REPLACEMENT; KNEE REPLACEMENT; MEDICAL SOCIETY; UNITED STATES;

ANESTHESIA, CONDUCTION; ANTIFIBRINOLYTIC AGENTS; ARTHROPLASTY; ARTHROPLASTY, REPLACEMENT, HIP; ARTHROPLASTY, REPLACEMENT, KNEE; HUMANS; ORTHOPEDIC SURGEONS; PRACTICE GUIDELINES AS TOPIC; SOCIETIES, MEDICAL; TRANEXAMIC ACID; UNITED STATES;

EID: 85060025637     PISSN: 10987339     EISSN: 15328651     Source Type: Journal    
DOI: 10.1136/rapm-2018-000024     Document Type: Article

References (18)

1. AAOS clinical practice guideline and systematic review methodology. Available: https://www.aaos.org/uploadedFiles/PreProduction/Quality/Guidelines_and_Reviews/guidelines/Guideline_and_Systematic_Review_Processes_v2.0_Final.pdf
2. Fillingham YA, Ramkumar DB, Jevsevar DS. The efficacy of tranexamic acid in total hip arthroplasty: a network meta-analysis. J Arthroplasty 2018:pii: S0883-5403(18)30593-X.
3. Maniar RN, Kumar G, Singhi T et al. Most effective regimen of tranexamic acid in knee arthroplasty: a prospective randomized controlled study in 240 patients. Clin Orthop Relat Res 2012;470:2605-12.
4. Wong J, Abrishami A, El Beheiry H et al. Topical application of tranexamic acid reduces postoperative blood loss in total knee arthroplasty: a randomized, controlled trial. J Bone Joint Surg Am 2010;92:2503-13.
5. Carvalho LH, Frois Temponi E, Machado Soares LF et al. Bleeding reduction after topical application of tranexamic acid together with Betadine solution in total knee arthroplasty. A randomised controlled study. Orthop Traumatol Surg Res 2015;101:83-7.
6. Sarzaeem MM, Razi M, Kazemian G et al. Comparing efficacy of three methods of tranexamic acid administration in reducing hemoglobin drop following total knee arthroplasty. J Arthroplasty 2014;29:1521-4.
7. Barrachina B, Lopez-Picado A, Remon M et al. Tranexamic acid compared with placebo for reducing total blood loss in hip replacement surgery: A randomized clinical trial. Anesth Analg 2016;122:986-95.
8. Lin PC, Hsu CH, Huang CC et al. The blood-saving effect of tranexamic acid in minimally invasive total knee replacement: is an additional pre-operative injection effective? J Bone Joint Surg Br 2012;94:932-6.
9. Hourlier H, Fennema P. Single tranexamic acid dose to reduce perioperative morbidity in primary total hip replacement: a randomised clinical trial. Hip Int 2014;24:63-8.
10. Imai N, Dohmae Y, Suda K et al. Tranexamic acid for reduction of blood loss during total hip arthroplasty. J Arthroplasty 2012;27:1838-43.
11. Dai L, Bevan D, Rangarajan S et al. Stabilization of fibrin clots by activated prothrombin complex concentrate and tranexamic acid in FVIII inhibitor plasma. Haemophilia 2011;17:8.
12. Duncan CM, Gillette BP, Jacob AK et al. Venous thromboembolism and mortality associated with tranexamic acid use during total hip and knee arthroplasty. J Arthroplasty 2015;30:272-6.
13. Poeran J, Rasul R, Suzuki S et al. Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety. BMJ 2014;349:g4829.
14. Sabbag OD, Abdel MP, Amundson AW et al. Tranexamic acid was safe in arthroplasty patients with a history of venous thromboembolism: a matched outcome study. J Arthroplasty 2017;32(9S):S246-S250.
15. Whiting DR, Gillette BP, Duncan C et al. Preliminary results suggest tranexamic acid is safe and effective in arthroplasty patients with severe comorbidities. Clin Orthop Relat Res 2014;472:66-72.
16. Hopewell S, Omar O, Hyde C et al. A systematic review of the effect of red blood cell transfusion on mortality: evidence from large-scale observational studies published between 2006 and 2010. BMJ Open 2013;3:e002154.
17. Koch CG, Khandwala F, Li L et al. Persistent effect of red cell transfusion on health-related quality of life after cardiac surgery. Ann Thorac Surg 2006;82:13-20.
18. Möhnle P, Snyder-Ramos SA, Miao Y et al. Postoperative red blood cell transfusion and morbid outcome in uncomplicated cardiac surgery patients. Intensive Care Med 2011;37:97-109.