Indoles derived from intestinal microbiota act via type I interferon signaling to limit graft-versus-host disease

Blood

Volumn 132, Issue 23, 2018, Pages 2506-2519

  Swimm, Alyson ^a   Giver, Cynthia R ^a   DeFilipp, Zachariah ^b   Rangaraju, Sravanti ^c   Sharma, Akshay ^d   Antonova, Alina Ulezko ^a   Sonowal, Robert ^a   Capaldo, Christopher ^a   Powell, Domonica ^a   Qayed, Muna ^a   Kalman, Daniel ^a,e   Waller, Edmund K ^a,f  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c INDIANA UNIVERSITY   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^e Center for Neurodegenerative Disease   (United States)

^f EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INDOLE 3 CARBOXALDEHYDE; INDOLE DERIVATIVE; INTERFERON; TRYPTOPHANASE; UNCLASSIFIED DRUG; CYTOKINE; INDOLE-3-CARBALDEHYDE;

ALLOGENIC BONE MARROW TRANSPLANTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL TRANSLOCATION; CELL DAMAGE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENTERITIS; ESCHERICHIA COLI; GRAFT VERSUS HOST REACTION; GRAFT VERSUS LEUKEMIA EFFECT; INTESTINE FLORA; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; ALLOGRAFT; ANIMAL; BONE MARROW TRANSPLANTATION; DISEASE MODEL; DRUG EFFECT; GENETICS; INTESTINE MUCOSA; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; PATHOLOGY;

ALLOGRAFTS; ANIMALS; BACTERIAL TRANSLOCATION; BONE MARROW TRANSPLANTATION; CYTOKINES; DISEASE MODELS, ANIMAL; ESCHERICHIA COLI; GASTROINTESTINAL MICROBIOME; GRAFT VS HOST DISEASE; INDOLES; INTERFERON TYPE I; INTESTINAL MUCOSA; MICE; MICE, KNOCKOUT;

EID: 85057717871     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2018-03-838193     Document Type: Article

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