Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and Is Critical to Trained Immunity

Cell

Volumn 175, Issue 6, 2018, Pages 1634-1650.e17

  Yao, Yushi ^a   Jeyanathan, Mangalakumari ^a   Haddadi, Siamak ^a   Barra, Nicole G ^b   Vaseghi Shanjani, Maryam ^a   Damjanovic, Daniela ^a   Lai, Rocky ^a   Afkhami, Sam ^a   Chen, Yonghong ^c   Dvorkin Gheva, Anna ^a   Robbins, Clinton S ^c   Schertzer, Jonathan D ^b   Xing, Zhou ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

CD8 T cells; IFN ; innate immune memory; lung; memory alveolar macrophages; Streptococcus pneumoniae; T cell help; trained immunity; viral infection

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCYTE CHEMOTACTIC PROTEIN 1;

ADENOVIRIDAE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; BACTERIAL IMMUNITY; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; ESCHERICHIA COLI; EX VIVO STUDY; FEMALE; HEMATOPOIETIC STEM CELL; IMMUNOLOGICAL MEMORY; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; LUNG ALVEOLUS MACROPHAGE; MONOCYTE; MOUSE; MUCOSAL IMMUNITY; NEUTROPHILIA; NONHUMAN; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE; T LYMPHOCYTE; VIRAL RESPIRATORY TRACT INFECTION; ANIMAL; BAGG ALBINO MOUSE; CYTOLOGY; HELPER CELL; IMMUNOLOGY; LUNG; RESPIRATORY MUCOSA; TRANSGENIC MOUSE;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; IMMUNITY, INNATE; IMMUNOLOGIC MEMORY; LUNG; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MONOCYTES; RESPIRATORY MUCOSA; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 85056968423     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2018.09.042     Document Type: Article

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