-
1
-
-
84865070369
-
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
-
[PubMed]
-
Jinek, M.; Chylinski, K.; Fonfara, I.; Hauer, M.; Doudna, J.A.; Charpentier, E. A programmable dual-RNAguided DNA endonuclease in adaptive bacterial immunity. Science 2012, 337, 816–821. [PubMed]
-
(2012)
Science
, vol.337
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
Charpentier, E.6
-
2
-
-
84887010498
-
Genome engineering using the CRISPR-Cas9 system
-
[PubMed]
-
Ran, F.A.; Hsu, P.D.; Wright, J.; Agarwala, V.; Scott, D.A.; Zhang, F. Genome engineering using the CRISPR-Cas9 system. Nat. Protoc. 2013, 8, 2281–2308. [PubMed]
-
(2013)
Nat. Protoc
, vol.8
, pp. 2281-2308
-
-
Ran, F.A.1
Hsu, P.D.2
Wright, J.3
Agarwala, V.4
Scott, D.A.5
Zhang, F.6
-
3
-
-
84903789654
-
Flotillins in receptor tyrosine kinase signaling and cancer
-
[PubMed]
-
Banning, A.; Kurrle, N.; Meister, M.; Tikkanen, R. Flotillins in receptor tyrosine kinase signaling and cancer. Cells 2014, 3, 129–149. [PubMed]
-
(2014)
Cells
, vol.3
, pp. 129-149
-
-
Banning, A.1
Kurrle, N.2
Meister, M.3
Tikkanen, R.4
-
4
-
-
84875078622
-
Mitogen-activated protein (MAP) kinase scaffolding proteins: A recount
-
[PubMed]
-
Meister, M.; Tomasovic, A.; Banning, A.; Tikkanen, R. Mitogen-activated protein (MAP) kinase scaffolding proteins: A recount. Int. J. Mol. Sci. 2013, 14, 4854–4884. [PubMed]
-
(2013)
Int. J. Mol. Sci
, vol.14
, pp. 4854-4884
-
-
Meister, M.1
Tomasovic, A.2
Banning, A.3
Tikkanen, R.4
-
5
-
-
84857746692
-
Flotillin-1/ reggie-2 protein plays dual role in activation of receptor-tyrosine kinase/mitogen-activated protein kinase signaling
-
[PubMed]
-
Amaddii, M.; Meister, M.; Banning, A.; Tomasovic, A.; Mooz, J.; Rajalingam, K.; Tikkanen, R. Flotillin-1/ reggie-2 protein plays dual role in activation of receptor-tyrosine kinase/mitogen-activated protein kinase signaling. J. Biol. Chem. 2012, 287, 7265–7278. [PubMed]
-
(2012)
J. Biol. Chem
, vol.287
, pp. 7265-7278
-
-
Amaddii, M.1
Meister, M.2
Banning, A.3
Tomasovic, A.4
Mooz, J.5
Rajalingam, K.6
Tikkanen, R.7
-
6
-
-
84866519402
-
Transcriptional regulation of flotillins by the extracellularly regulated kinases and retinoid X receptor complexes
-
[CrossRef] [PubMed]
-
Banning, A.; Ockenga, W.; Finger, F.; Siebrasse, P.; Tikkanen, R. Transcriptional regulation of flotillins by the extracellularly regulated kinases and retinoid X receptor complexes. PLoS ONE 2012, 7, e45514. [CrossRef] [PubMed]
-
(2012)
Plos ONE
, vol.7
-
-
Banning, A.1
Ockenga, W.2
Finger, F.3
Siebrasse, P.4
Tikkanen, R.5
-
7
-
-
84925850947
-
Cholinergic Transactivation of the EGFR in HaCaT Keratinocytes Stimulates a Flotillin-1 Dependent MAPK-Mediated Transcriptional Response
-
[CrossRef] [PubMed]
-
Kuhne, S.; Ockenga, W.; Banning, A.; Tikkanen, R. Cholinergic Transactivation of the EGFR in HaCaT Keratinocytes Stimulates a Flotillin-1 Dependent MAPK-Mediated Transcriptional Response. Int. J. Mol. Sci. 2015, 16, 6447–6463. [CrossRef] [PubMed]
-
(2015)
Int. J. Mol. Sci
, vol.16
, pp. 6447-6463
-
-
Kuhne, S.1
Ockenga, W.2
Banning, A.3
Tikkanen, R.4
-
8
-
-
0035122581
-
Flotillin-1: Gene structure: CDNA cloning from human lung and the identification of alternative polyadenylation signals
-
[CrossRef]
-
Edgar, A.J.; Polak, J.M. Flotillin-1: Gene structure: cDNA cloning from human lung and the identification of alternative polyadenylation signals. Int. J. Biochem. Cell Biol. 2001, 33, 53–64. [CrossRef]
-
(2001)
Int. J. Biochem. Cell Biol
, vol.33
, pp. 53-64
-
-
Edgar, A.J.1
Polak, J.M.2
-
9
-
-
84896719298
-
Flotillins directly interact with gamma-catenin and regulate epithelial cell-cell adhesion
-
[CrossRef] [PubMed]
-
Kurrle, N.; Vollner, F.; Eming, R.; Hertl, M.; Banning, A.; Tikkanen, R. Flotillins directly interact with gamma-catenin and regulate epithelial cell-cell adhesion. PLoS ONE 2013, 8, e84393. [CrossRef] [PubMed]
-
(2013)
Plos ONE
, vol.8
-
-
Kurrle, N.1
Vollner, F.2
Eming, R.3
Hertl, M.4
Banning, A.5
Tikkanen, R.6
-
10
-
-
84976570264
-
Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes
-
[CrossRef] [PubMed]
-
Vollner, F.; Ali, J.; Kurrle, N.; Exner, Y.; Eming, R.; Hertl, M.; Banning, A.; Tikkanen, R. Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes. Sci. Rep. 2016, 6, 28820. [CrossRef] [PubMed]
-
(2016)
Sci. Rep
, vol.6
, pp. 28820
-
-
Vollner, F.1
Ali, J.2
Kurrle, N.3
Exner, Y.4
Eming, R.5
Hertl, M.6
Banning, A.7
Tikkanen, R.8
-
11
-
-
84996548960
-
Identification of small molecule compounds for pharmacological chaperone therapy of aspartylglucosaminuria
-
[CrossRef] [PubMed]
-
Banning, A.; Gulec, C.; Rouvinen, J.; Gray, S.J.; Tikkanen, R. Identification of small molecule compounds for pharmacological chaperone therapy of aspartylglucosaminuria. Sci. Rep. 2016, 6, 37583. [CrossRef] [PubMed]
-
(2016)
Sci. Rep
, vol.6
, pp. 37583
-
-
Banning, A.1
Gulec, C.2
Rouvinen, J.3
Gray, S.J.4
Tikkanen, R.5
-
12
-
-
0035871210
-
Molecular pathogenesis of a disease: Structural consequences of aspartylglucosaminuria mutations
-
[CrossRef] [PubMed]
-
Saarela, J.; Laine, M.; Oinonen, C.; von Schantz, C.; Jalanko, A.; Rouvinen, J.; Peltonen, L. Molecular pathogenesis of a disease: Structural consequences of aspartylglucosaminuria mutations. Hum. Mol. Genet. 2001, 10, 983–995. [CrossRef] [PubMed]
-
(2001)
Hum. Mol. Genet
, vol.10
, pp. 983-995
-
-
Saarela, J.1
Laine, M.2
Oinonen, C.3
Von Schantz, C.4
Jalanko, A.5
Rouvinen, J.6
Peltonen, L.7
-
13
-
-
84929665802
-
Toward whole-transcriptome editing with CRISPR-Cas 9
-
[CrossRef] [PubMed]
-
Heckl, D.; Charpentier, E. Toward whole-transcriptome editing with CRISPR-Cas 9. Mol. Cell 2015, 58, 560–562. [CrossRef] [PubMed]
-
(2015)
Mol. Cell
, vol.58
, pp. 560-562
-
-
Heckl, D.1
Charpentier, E.2
-
14
-
-
84929160074
-
CRISPR germline engineering–the community speaks
-
[CrossRef] [PubMed]
-
Bosley, K.S.; Botchan, M.; Bredenoord, A.L.; Carroll, D.; Charo, R.A.; Charpentier, E.; Cohen, R.; Corn, J.; Doudna, J.; Feng, G. et al. CRISPR germline engineering–the community speaks. Nat. Biotechnol. 2015, 33, 478–486. [CrossRef] [PubMed]
-
(2015)
Nat. Biotechnol
, vol.33
, pp. 478-486
-
-
Bosley, K.S.1
Botchan, M.2
Bredenoord, A.L.3
Carroll, D.4
Charo, R.A.5
Charpentier, E.6
Cohen, R.7
Corn, J.8
Doudna, J.9
Feng, G.10
-
15
-
-
84926069381
-
CRISPR-Cas9: How research on a bacterial RNA-guided mechanism opened new perspectives in biotechnology and biomedicine
-
[CrossRef] [PubMed]
-
Charpentier, E. CRISPR-Cas9: How research on a bacterial RNA-guided mechanism opened new perspectives in biotechnology and biomedicine. EMBO Mol. Med. 2015, 7, 363–365. [CrossRef] [PubMed]
-
(2015)
EMBO Mol. Med
, vol.7
, pp. 363-365
-
-
Charpentier, E.1
-
16
-
-
84900314611
-
CRISPR-Cas systems for editing, regulating and targeting genomes
-
[CrossRef] [PubMed]
-
Sander, J.D.; Joung, J.K. CRISPR-Cas systems for editing, regulating and targeting genomes. Nat. Biotechnol. 2014, 32, 347–355. [CrossRef] [PubMed]
-
(2014)
Nat. Biotechnol
, vol.32
, pp. 347-355
-
-
Sander, J.D.1
Joung, J.K.2
-
17
-
-
84890033064
-
Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients
-
[CrossRef] [PubMed]
-
Schwank, G.; Koo, B.K.; Sasselli, V.; Dekkers, J.F.; Heo, I.; Demircan, T.; Sasaki, N.; Boymans, S.; Cuppen, E.; van der Ent, C.K. et al. Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. Cell Stem Cell 2013, 13, 653–658. [CrossRef] [PubMed]
-
(2013)
Cell Stem Cell
, vol.13
, pp. 653-658
-
-
Schwank, G.1
Koo, B.K.2
Sasselli, V.3
Dekkers, J.F.4
Heo, I.5
Demircan, T.6
Sasaki, N.7
Boymans, S.8
Cuppen, E.9
Van Der Ent, C.K.10
-
18
-
-
84930691710
-
Mechanisms and regulation of alternative pre-mRNA splicing
-
[CrossRef] [PubMed]
-
Lee, Y.; Rio, D.C.: Mechanisms and regulation of alternative pre-mRNA splicing. Annu. Rev. Biochem. 2015, 84, 291–323. [CrossRef] [PubMed]
-
(2015)
Annu. Rev. Biochem
, vol.84
, pp. 291-323
-
-
Lee, Y.1
Rio, D.C.2
-
19
-
-
84951568527
-
RNA mis-splicing in disease
-
[CrossRef] [PubMed]
-
Scotti, M.M.; Swanson, M.S. RNA mis-splicing in disease. Nat. Rev. Genet. 2016, 17, 19–32. [CrossRef] [PubMed]
-
(2016)
Nat. Rev. Genet
, vol.17
, pp. 19-32
-
-
Scotti, M.M.1
Swanson, M.S.2
-
20
-
-
33644764129
-
An exon skippingassociated nonsense mutation in the dystrophin gene uncovers a complex interplay between multiple antagonistic splicing elements
-
[CrossRef] [PubMed]
-
Disset, A.; Bourgeois, C.F.; Benmalek, N.; Claustres, M.; Stevenin, J.; Tuffery-Giraud, S. An exon skippingassociated nonsense mutation in the dystrophin gene uncovers a complex interplay between multiple antagonistic splicing elements. Hum. Mol. Genet. 2006, 15, 999–1013. [CrossRef] [PubMed]
-
(2006)
Hum. Mol. Genet
, vol.15
, pp. 999-1013
-
-
Disset, A.1
Bourgeois, C.F.2
Benmalek, N.3
Claustres, M.4
Stevenin, J.5
Tuffery-Giraud, S.6
-
21
-
-
84881230554
-
Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS)
-
[CrossRef] [PubMed]
-
Korvatska, O.; Strand, N.S.; Berndt, J.D.; Strovas, T.; Chen, D.H.; Leverenz, J.B.; Kiianitsa, K.; Mata, I.F.; Karakoc, E.; Greenup, J.L. et al. Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS). Hum. Mol. Genet. 2013, 22, 3259–3268. [CrossRef] [PubMed]
-
(2013)
Hum. Mol. Genet
, vol.22
, pp. 3259-3268
-
-
Korvatska, O.1
Strand, N.S.2
Berndt, J.D.3
Strovas, T.4
Chen, D.H.5
Leverenz, J.B.6
Kiianitsa, K.7
Mata, I.F.8
Karakoc, E.9
Greenup, J.L.10
-
22
-
-
84919687395
-
Nonsense-mediated decay in genetic disease: Friend or foe?
-
[CrossRef] [PubMed]
-
Miller, J.N.; Pearce, D.A. Nonsense-mediated decay in genetic disease: Friend or foe? Mutat. Res. Rev. Mutat. Res. 2014, 762, 52–64. [CrossRef] [PubMed]
-
(2014)
Mutat. Res. Rev. Mutat. Res
, vol.762
, pp. 52-64
-
-
Miller, J.N.1
Pearce, D.A.2
-
23
-
-
0037073697
-
Flotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation
-
[CrossRef] [PubMed]
-
Morrow, I.C.; Rea, S.; Martin, S.; Prior, I.A.; Prohaska, R.; Hancock, J.F.; James, D.E.; Parton, R.G. Flotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation. J. Biol. Chem. 2002, 277, 48834–48841. [CrossRef] [PubMed]
-
(2002)
J. Biol. Chem
, vol.277
, pp. 48834-48841
-
-
Morrow, I.C.1
Rea, S.2
Martin, S.3
Prior, I.A.4
Prohaska, R.5
Hancock, J.F.6
James, D.E.7
Parton, R.G.8
-
24
-
-
18144396107
-
The stomatin/prohibitin/flotillin/HflK/C domain of flotillin-1 contains distinct sequences that direct plasma membrane localization and protein interactions in 3T3-L1 adipocytes
-
[CrossRef] [PubMed]
-
Liu, J.; Deyoung, S.M.; Zhang, M.; Dold, L.H.; Saltiel, A.R. The stomatin/prohibitin/flotillin/HflK/C domain of flotillin-1 contains distinct sequences that direct plasma membrane localization and protein interactions in 3T3-L1 adipocytes. J. Biol. Chem. 2005, 280, 16125–16134. [CrossRef] [PubMed]
-
(2005)
J. Biol. Chem
, vol.280
, pp. 16125-16134
-
-
Liu, J.1
Deyoung, S.M.2
Zhang, M.3
Dold, L.H.4
Saltiel, A.R.5
|