The ups and downs of low-carbohydrate diets in the management of Type 1 diabetes: a review of clinical outcomes

Diabetic Medicine

Volumn 36, Issue 3, 2019, Pages 326-334

  Seckold, R ^a,b   Fisher, E ^a   de Bock, M ^c   King, B R ^a,b   Smart, C E ^a,b  

^a JOHN HUNTER CHILDREN S HOSPITAL   (Australia)

^b UNIVERSITY OF NEWCASTLE   (Australia)

^c UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; GLUCOSE;

BLOOD GLUCOSE MONITORING; CLINICAL OUTCOME; DIABETIC PATIENT; DIET THERAPY; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LOW CARBOHYDRATE DIET; REVIEW; ADVERSE EVENT; BLOOD; CARBOHYDRATE DIET; METABOLISM; PHARMACOLOGY; PHYSIOLOGIC MONITORING; PRACTICE GUIDELINE; PROCEDURES; TREATMENT OUTCOME;

BLOOD GLUCOSE; BLOOD GLUCOSE SELF-MONITORING; DIABETES MELLITUS, TYPE 1; DIET, CARBOHYDRATE-RESTRICTED; DIETARY CARBOHYDRATES; HUMANS; MONITORING, PHYSIOLOGIC; PRACTICE GUIDELINES AS TOPIC; TREATMENT OUTCOME;

EID: 85056729924     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/dme.13845     Document Type: Review

References (59)

1. Tattersall RB. The quest for normoglycaemia: a historical perspective. Diabet Med 1994; 11: 618–635.
2. Mazur A. Why were “starvation” diets promoted for diabetes in the pre-insulin period? Nutrition J 2011;10(23).
3. Graham GCA, Roberton HEW. The High Carbohydrate Diet in the Treatment of Diabetes Mellitus. Lancet 1932; 990–993.
4. Nixon JA. Advantages to the diabetic of a diet rich in carbohydrates. Br Med J 1930; 1: 326–327.
5. Diabetes Control and Complications Trial Research Group, Nathan DM, Genuth S, Lachin J, Cleary P, Crofford O et al. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993;329:977–986.
6. Dafne Study Group. Training in flexible, intensive insulin management to enable dietary freedom in people with type 1 diabetes: dose adjustment for normal eating (DAFNE) randomised controlled trial. BMJ 2002; 325: 746.
7. Delamater AM, Smith JA, Kurtz SM, White NH. Dietary skills and adherence in children with type I diabetes mellitus. Diabetes Educ 1988; 14: 33–36.
8. Bell KJ, Smart CE, Steil GM, Brand-Miller JC, King B, Wolpert HA. Impact of fat, protein, and glycemic index on postprandial glucose control in type 1 diabetes: implications for intensive diabetes management in the continuous glucose monitoring era. Diabetes Care 2015; 38: 1008–1015.
9. Ranjan A, Schmidt S, Damm-Frydenberg C, Holst JJ, Madsbad S, Norgaard K. Short-term effects of a low carbohydrate diet on glycaemic variables and cardiovascular risk markers in patients with type 1 diabetes: A randomized open-label crossover trial. Diabetes Obes Metab 2017; 19: 1479–1484.
10. Younger LR, King J, Steiner DF. Hepatic proliferative response to insulin in severe alloxan diabetes. Cancer Res 1966; 26: 1408–1414.
11. Stout RW, Bierman EL, Ross R. Effect of insulin on the proliferation of cultured primate arterial smooth muscle cells. Circ Res 1975; 36: 319–327.
12. Chiarelli F, Giannini C, Mohn A. Growth, growth factors and diabetes. Eur J Endocrinol 2004; 151(Suppl. 3): U109–117.
13. Hill DJ, Milner RD. Insulin as a growth factor. Pediatric research. 1985; 19(9): 879–86.
14. de Bock M, Lobley K, Anderson D, Davis E, Donaghue K, Pappas M et al. Endocrine and metabolic consequences due to restrictive carbohydrate diets in children with type 1 diabetes: An illustrative case series. Pediatr Diabetes 2018; 19: 129–137.
15. Lennerz BS, Barton A, Bernstein RK, Dikeman RD, Diulus C, Hallberg S et al. Management of Type 1 Diabetes With a Very Low-Carbohydrate Diet. Pediatrics 2018;141(6).
16. Wheeler ML, Dunbar SA, Jaacks LM, Karmally W, Mayer-Davis EJ, Wylie-Rosett J et al. Macronutrients, food groups, and eating patterns in the management of diabetes: a systematic review of the literature, 2010. Diabetes Care 2012; 35: 434–445.
17. Feinman RD, Pogozelski WK, Astrup A, Bernstein RK, Fine EJ, Westman EC et al. Dietary carbohydrate restriction as the first approach in diabetes management: critical review and evidence base. Nutrition 2015; 31: 1–13.
18. Scientific Advisory Committee on Nutrition. Dietary Reference Values for Energy. In: Scientific Advisory Committee on Nutrition, editor. London: Public Health England; 2011.
19. Gilbertson HR, Reed K, Clark S, Francis KL, Cameron FJ. An audit of the dietary intake of Australian children with type 1 diabetes. Nutr Diabetes 2018; 8: 10.
20. Powers MA, Gal RL, Connor CG, Mangan M, Maahs DM, Clements MA et al. Eating patterns and food intake of persons with type 1 diabetes within the T1D exchange. Diabetes Res Clin Pract 2018; 141: 217–228.
21. Dyson PA, Twenefour D, Breen C, Duncan A, Elvin E, Goff L et al. Diabetes UK evidence-based nutrition guidelines for the prevention and management of diabetes. Diabet Med 2018; 35: 541–547.
22. Mayer-Davis EJ, Nichols M, Liese AD, Bell RA, Dabelea DM, Johansen JM et al. Dietary intake among youth with diabetes: the SEARCH for Diabetes in Youth Study. J Am Diet Assoc 2006; 106: 689–697.
23. Leow ZZX, Guelfi KJ, Davis EA, Jones TW, Fournier PA. The glycaemic benefits of a very-low-carbohydrate ketogenic diet in adults with Type 1 diabetes mellitus may be opposed by increased hypoglycaemia risk and dyslipidaemia. Diabet Med 2018; 35: 1258–1263.
24. Krebs JD, Parry Strong A, Cresswell P, Reynolds AN, Hanna A, Haeusler S. A randomised trial of the feasibility of a low carbohydrate diet vs standard carbohydrate counting in adults with type 1 diabetes taking body weight into account. Asia Pac J Clin Nutr 2016; 25: 78–84.
25. Sacks FM, Lichtenstein AH, Wu JHY, Appel LJ, Creager MA, Kris-Etherton PM et al. Dietary Fats and Cardiovascular Disease: A Presidential Advisory From the American Heart Association. Circulation 2017; 136: e1–e23.
26. National Health and Medical Research Council. Australian Dietary Guidelines 2013 Available at https://www.nhmrc.gov.au/guidelines-publications/n55. Last accessed 1 July 2018
27. Zinn C, Rush A, Johnson R. Assessing the nutrient intake of a low-carbohydrate, high-fat (LCHF) diet: a hypothetical case study design. BMJ Open 2018; 8: e018846.
28. Sonnweber T, Ress C, Nairz M, Theurl I, Schroll A, Murphy AT et al. High-fat diet causes iron deficiency via hepcidin-independent reduction of duodenal iron absorption. J Nutr Biochem 2012; 23: 1600–1608.
29. Smart CE, Annan F, Bruno LPC, Higgins LA, Acerini CL. Nutritional management in children and adolescents with diabetes. Pediatr Diabetes 2014;15(Supplement 20):135–153.
30. Crowley E, Williams L, Brown L. How do mothers juggle the special dietary needs of one child while feeding the family? A qualitative exploration. Nutrition and Dietetics 2012; 69: 272–277.
31. Flammarion S, Santos C, Guimber D, Jouannic L, Thumerelle C, Gottrand F et al. Diet and nutritional status of children with food allergies. Pediatr Allergy Immunol 2011; 22: 161–165.
32. Whitfield-Brown L, Hamer O, Ellahi B, Burden S, Durrington P. An investigation to determine the nutritional adequacy and individuals experience of a very low fat diet used to treat type V hypertriglyceridaemia. J Hum Nutr Diet 2009; 22: 232–238.
33. Nielsen JV, Gando C, Joensson E, Paulsson C. Low carbohydrate diet in type 1 diabetes, long-term improvement and adherence: A clinical audit. Diabetol Metab Syndr 2012; 4: 23.
34. Caccavale LJ, Nansel TR, Quick V, Lipsky LM, Laffel LM, Mehta SN. Associations of disordered eating behavior with the family diabetes environment in adolescents with Type 1 diabetes. J Dev Behav Pediatr 2015; 36: 8–13.
35. Toni G, Berioli MG, Cerquiglini L, Ceccarini G, Grohmann U, Principi N et al. Eating Disorders and Disordered Eating Symptoms in Adolescents with Type 1 Diabetes. Nutrients 2017;9:pii: E906.
36. Nielsen JV, Jonsson E, Ivarsson A. A low carbohydrate diet in type 1 diabetes: clinical experience–a brief report. Ups J Med Sci 2005; 110: 267–273.
37. van Wyk HJ, Davis RE, Davies JS. A critical review of low-carbohydrate diets in people with Type 2 diabetes. Diabet Med 2016; 33: 148–157.
38. Turton JL, Raab R, Rooney KB. Low-carbohydrate diets for type 1 diabetes mellitus: A systematic review. PLoS One 2018; 13(3): e0194987.
39. O'Neill D, Westman EC, Bernstein RK. The Effects of a low-carbohydrate regimen on glycemia control and serum lipids in diabetes mellitus. Metab Syndr Relat Disord 2003; 1: 291–298.
40. Herron A, Sullivan C, Brouillard E, Steenkamp D. Late to the Party: Importance of Dietary Fat and Protein in the Intensive Management of Type 1 Diabetes. A Case Report. J Endrocr Soc 2017; 1: 1002–1005.
41. Bernstein RK. Virtually continuous euglycemia for 5 yr in a labile juvenile-onset diabetic patient under noninvasive closed-loop control. Diabetes Care 1980; 3: 140–143.
42. Mayer-Davis EJ, Laffel LM, Buse JB. Management of Type 1 Diabetes With a Very Low-Carbohydrate Diet: A Word of Caution. Pediatrics 2018;142: pii: e20181536B.
43. Seckold RL, Howley P, King BR, Bell K, Smart CE. Grazing in young children with type 1 diabetes is associated with higher HbA1c [abstract]. Diabetes 2018;67(Suppl. 1):1368–P.
44. Nansel TR, Lipsky LM, Liu A. Greater diet quality is associated with more optimal glycemic control in a longitudinal study of youth with type 1 diabetes. Am J Clin Nutr 2016; 104: 81–87.
45. Delahanty LM, Nathan DM, Lachin JM, Hu FB, Cleary PA, Ziegler GK et al. Association of diet with glycated hemoglobin during intensive treatment of type 1 diabetes in the Diabetes Control and Complications Trial. Am J Clin Nutr 2009; 89: 518–524.
46. Rudolf MC, Sherwin RS, Markowitz R, Bates SE, Genel M, Hochstadt J et al. Effect of intensive insulin treatment on linear growth in the young diabetic patient. J Pediatr 1982; 101: 333–339.
47. Amiel SA, Sherwin RS, Hintz RL, Gertner JM, Press CM, Tamborlane WV. Effect of diabetes and its control on insulin-like growth factors in the young subject with type I diabetes. Diabetes 1984; 33: 1175–1179.
48. Ranjan A, Schmidt S, Damm-Frydenberg C, Steineck I, Clausen TR, Holst JJ et al. Low-Carbohydrate Diet Impairs the Effect of Glucagon in the Treatment of Insulin-Induced Mild Hypoglycemia: A Randomized Crossover Study. Diabetes Care 2017; 40: 132–135.
49. Chalasani S, Fischer J. South Beach Diet associated ketoacidosis: a case report. J Med Case Rep 2008; 2: 45.
50. Sloan G, Ali A, Webster J. A rare cause of metabolic acidosis: ketoacidosis in a non-diabetic lactating woman. Endocrinol Diabetes Metab Case Rep 2017;2017.
51. Chen TY, Smith W, Rosenstock JL, Lessnau KD. A life-threatening complication of Atkins diet. Lancet 2006; 367: 958.
52. Kanikarla-Marie P, Jain SK. Hyperketonemia and ketosis increase the risk of complications in type 1 diabetes. Free Radic Biol Med 2016; 95: 268–277.
53. Inzucchi SE, Bergenstal RM, Buse JB, Diamant M, Ferrannini E, Nauck M et al. Management of hyperglycaemia in type 2 diabetes, 2015: a patient-centred approach. Update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetologia 2015; 58: 429–442.
54. Kossoff EH, Zupec-Kania BA, Amark PE, Ballaban-Gil KR, Christina Bergqvist AG, Blackford R et al. Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study Group. Epilepsia 2009; 50: 304–317.
55. Brand-Miller J, Hayne S, Petocz P, Colagiuri S. Low-glycemic index diets in the management of diabetes: a meta-analysis of randomized controlled trials. Diabetes Care 2003; 26: 2261–2267.
56. Bozzetto L, Giorgini M, Alderisio A, Costagliola L, Giacco A, Riccardi G et al. Glycaemic load versus carbohydrate counting for insulin bolus calculation in patients with type 1 diabetes on insulin pump. Acta Diabetol 2015; 52: 865–871.
57. Overby NC, Margeirsdottir HD, Brunborg C, Andersen LF, Dahl-Jorgensen K. The influence of dietary intake and meal pattern on blood glucose control in children and adolescents using intensive insulin treatment. Diabetologia 2007; 50: 2044–2051.
58. Cobry E, McFann K, Messer L, Gage V, VanderWel B, Horton L et al. Timing of meal insulin boluses to achieve optimal postprandial glycemic control in patients with type 1 diabetes. Diabetes Technol Ther 2010; 12: 173–177.
59. Schmidt S, Schelde B, Norgaard K. Effects of advanced carbohydrate counting in patients with type 1 diabetes: a systematic review. Diabet Med 2014; 31: 886–896.