-
2
-
-
84856599478
-
French results of the ARESC study: Clinical aspects and epidemiology of antimicrobial resistance in female patients with cystitis. Implications for empiric therapy
-
Neuzillet Y, Naber KG, Schito G et al. French results of the ARESC study: clinical aspects and epidemiology of antimicrobial resistance in female patients with cystitis. Implications for empiric therapy. Med Mal Infect 2012; 42: 66–75.
-
(2012)
Med Mal Infect
, vol.42
, pp. 66-75
-
-
Neuzillet, Y.1
Naber, K.G.2
Schito, G.3
-
3
-
-
84937428422
-
Epidemiology, clinical presentation, laboratory diagnosis, antimicrobial resistance, and antimicrobial management of invasive Salmonella infections
-
Crump JA, Sjölund-Karlsson M, Gordon MA et al. Epidemiology, clinical presentation, laboratory diagnosis, antimicrobial resistance, and antimicrobial management of invasive Salmonella infections. Clin Microbiol Rev 2015; 28: 901–37.
-
(2015)
Clin Microbiol Rev
, vol.28
, pp. 901-937
-
-
Crump, J.A.1
Sjölund-Karlsson, M.2
Gordon, M.A.3
-
4
-
-
85022040487
-
Sexually-transmitted infections: Challenges ahead
-
Unemo M, Bradshaw CS, Hocking JS et al. Sexually-transmitted infections: challenges ahead. Lancet Infect Dis 2017; 17: e235–79.
-
(2017)
Lancet Infect Dis
, vol.17
, pp. e235-e279
-
-
Unemo, M.1
Bradshaw, C.S.2
Hocking, J.S.3
-
5
-
-
85026806895
-
Extensively drug-resistant tuberculosis in India: Current evidence on diagnosis and management
-
Prasad R, Singh A, Balasubramanian V et al. Extensively drug-resistant tuberculosis in India: current evidence on diagnosis and management. Indian J Med Res 2017; 145: 271–93.
-
(2017)
Indian J Med Res
, vol.145
, pp. 271-293
-
-
Prasad, R.1
Singh, A.2
Balasubramanian, V.3
-
6
-
-
15544384259
-
Antibacterial drug discovery: Is it all downhill from here?
-
Projan SJ, Shlaes DM. Antibacterial drug discovery: is it all downhill from here? Clin Microbiol Infect 2004; 10 Suppl 4: 18–22.
-
(2004)
Clin Microbiol Infect
, vol.10
, pp. 18-22
-
-
Projan, S.J.1
Shlaes, D.M.2
-
7
-
-
33845903833
-
Drugs for bad bugs: Confronting the challenges of antibacterial discovery
-
Payne DJ, Gwynn MN, Holmes DJ et al. Drugs for bad bugs: confronting the challenges of antibacterial discovery. Nat Rev Drug Discov 2007; 6: 29–40.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 29-40
-
-
Payne, D.J.1
Gwynn, M.N.2
Holmes, D.J.3
-
8
-
-
78751477224
-
Challenges of antibacterial discovery
-
Silver LL. Challenges of antibacterial discovery. Clin Microbiol Rev 2011; 24: 71–109.
-
(2011)
Clin Microbiol Rev
, vol.24
, pp. 71-109
-
-
Silver, L.L.1
-
9
-
-
0036467238
-
The United States food and drug administration and the end of antibiotics
-
Shlaes DM, Moellering RC. The United States Food and Drug Administration and the end of antibiotics. Clin Infect Dis 2002; 34: 420–2.
-
(2002)
Clin Infect Dis
, vol.34
, pp. 420-422
-
-
Shlaes, D.M.1
Moellering, R.C.2
-
10
-
-
80051705390
-
Regulatory opportunities to encourage technology solutions to antibacterial drug resistance
-
Finch R; BSAC Working Party on The Urgent Need: Regenerating Antibacterial Drug Discovery and Development. Regulatory opportunities to encourage technology solutions to antibacterial drug resistance. J Antimicrob Chemother 2011; 66: 1945–7.
-
(2011)
J Antimicrob Chemother
, vol.66
, pp. 1945-1947
-
-
Finch, R.1
-
12
-
-
84898000971
-
Of stewardship, motherhood and apple pie
-
Livermore DM. Of stewardship, motherhood and apple pie. Int J AntimicrobAgents2014;43:319–22.
-
Int J AntimicrobAgents2014
, vol.43
, pp. 319-322
-
-
Livermore, D.M.1
-
13
-
-
84879099071
-
Revolutionising bacteriology to improve treatment outcomes and antibiotic stewardship
-
Livermore DM, Wain J. Revolutionising bacteriology to improve treatment outcomes and antibiotic stewardship. Infect Chemother 2013; 45: 1–10.
-
(2013)
Infect Chemother
, vol.45
, pp. 1-10
-
-
Livermore, D.M.1
Wain, J.2
-
14
-
-
84991447222
-
Implementation of rapid diagnostics with antimicrobial stewardship
-
Minejima E, Wong-Beringer A. Implementation of rapid diagnostics with antimicrobial stewardship. Expert Rev Anti Infect Ther 2016; 14: 1065–75.
-
(2016)
Expert Rev Anti Infect Ther
, vol.14
, pp. 1065-1075
-
-
Minejima, E.1
Wong-Beringer, A.2
-
17
-
-
85061192784
-
-
The Pew Charitable Trusts. Antibiotic Resistance Project. http://www.pewtrusts.org/en/projects/antibiotic-resistance-project.
-
Antibiotic Resistance Project
-
-
-
18
-
-
85014891792
-
Economic incentives for antibacterial drug development: Literature review and considerations from the Transatlantic Task Force on Antimicrobial Resistance
-
Sciarretta K, Røttingen JA, Opalska A et al. Economic incentives for antibacterial drug development: literature review and considerations from the Transatlantic Task Force on Antimicrobial Resistance. Clin Infect Dis 2016; 63: 1470–4.
-
(2016)
Clin Infect Dis
, vol.63
, pp. 1470-1474
-
-
Sciarretta, K.1
Røttingen, J.A.2
Opalska, A.3
-
20
-
-
85016311967
-
A risk assessment of antibiotic pan-drug-resistance in the UK: Bayesian analysis of an expert elicitation study
-
Carter D, Charlett A, Conti S et al. A risk assessment of antibiotic pan-drug-resistance in the UK: Bayesian analysis of an expert elicitation study. Antibiotics (Basel) 2017; 6: E9.
-
(2017)
Antibiotics (Basel)
, vol.6
, pp. E9
-
-
Carter, D.1
Charlett, A.2
Conti, S.3
-
23
-
-
85099722078
-
-
0. http://news.bbc.co.uk/1/hi/magazine/7121136.stm.
-
0
-
-
-
24
-
-
33845321413
-
The emergence of antibiotic resistance by mutation
-
Woodford N, Ellington MJ. The emergence of antibiotic resistance by mutation. Clin Microbiol Infect 2007; 13: 5–18.
-
(2007)
Clin Microbiol Infect
, vol.13
, pp. 5-18
-
-
Woodford, N.1
Ellington, M.J.2
-
25
-
-
0023583815
-
Clinical significance of b-lactamase induction and stable derepression in Gram-negative rods
-
Livermore DM. Clinical significance of b-lactamase induction and stable derepression in Gram-negative rods. Eur J Clin Microbiol 1987; 6: 439–45.
-
(1987)
Eur J Clin Microbiol
, vol.6
, pp. 439-445
-
-
Livermore, D.M.1
-
26
-
-
0034869795
-
Risk factors for emergence of resistance to broad-spectrum cephalosporins among Enterobacter spp
-
Kaye KS, Cosgrove S, Harris A et al. Risk factors for emergence of resistance to broad-spectrum cephalosporins among Enterobacter spp. Antimicrob Agents Chemother 2001; 45: 2628–30.
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 2628-2630
-
-
Kaye, K.S.1
Cosgrove, S.2
Harris, A.3
-
28
-
-
84920171570
-
Bacterial resistance to leucyl-tRNA synthetase inhibitor GSK2251052 develops during treatment of complicated urinary tract infections
-
O’Dwyer K, Spivak AT, Ingraham K et al. Bacterial resistance to leucyl-tRNA synthetase inhibitor GSK2251052 develops during treatment of complicated urinary tract infections. Antimicrob Agents Chemother 2015; 59: 289–98.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 289-298
-
-
O’Dwyer, K.1
Spivak, A.T.2
Ingraham, K.3
-
29
-
-
84940901399
-
In vitro selection of ceftazidime/avibactam resistance in Enterobacteriaceae with KPC-3 carbapenemase
-
Livermore DM, Warner M, Jamrozy D et al. In vitro selection of ceftazidime/avibactam resistance in Enterobacteriaceae with KPC-3 carbapenemase. Antimicrob Agents Chemother 2015; 59: 5324–30.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 5324-5330
-
-
Livermore, D.M.1
Warner, M.2
Jamrozy, D.3
-
30
-
-
84995524184
-
Clinical outcomes, drug toxicity, and emergence of ceftazidime/avibactam resistance among patients treated for carbapenem-resistant Enterobacteriaceae infections
-
Shields RK, Potoski BA, Haidar G et al. Clinical outcomes, drug toxicity, and emergence of ceftazidime/avibactam resistance among patients treated for carbapenem-resistant Enterobacteriaceae infections. Clin Infect Dis 2016; 63: 1615–8.
-
(2016)
Clin Infect Dis
, vol.63
, pp. 1615-1618
-
-
Shields, R.K.1
Potoski, B.A.2
Haidar, G.3
-
31
-
-
85035049407
-
Emergence of ceftolozane/ tazobactam-resistant Pseudomonas aeruginosa during treatment is mediated by a single AmpC structural mutation
-
MacVane SH, Pandey R, Steed LL et al. Emergence of ceftolozane/ tazobactam-resistant Pseudomonas aeruginosa during treatment is mediated by a single AmpC structural mutation. Antimicrob Agents Chemother 2017;61:e01183-17.
-
(2017)
Antimicrob Agents Chemother
, vol.61
, pp. e01183-e01217
-
-
MacVane, S.H.1
Pandey, R.2
Steed, L.L.3
-
32
-
-
85043341833
-
Mechanisms leading to in vivo ceftolozane/tazobactam resistance development during the treatment of infections caused by MDR Pseudomonas aeruginosa
-
Fraile-Ribot PA, Cabot G, Mulet X et al. Mechanisms leading to in vivo ceftolozane/tazobactam resistance development during the treatment of infections caused by MDR Pseudomonas aeruginosa. J Antimicrob Chemother 2018; 73: 658–63.
-
(2018)
J Antimicrob Chemother
, vol.73
, pp. 658-663
-
-
Fraile-Ribot, P.A.1
Cabot, G.2
Mulet, X.3
-
33
-
-
77957371596
-
Origin and molecular evolution of the determinant of methicillin resistance in staphylococci
-
Tsubakishita S, Kuwahara-Arai K, Sasaki T et al. Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. Antimicrob Agents Chemother 2010; 54: 4352–9.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 4352-4359
-
-
Tsubakishita, S.1
Kuwahara-Arai, K.2
Sasaki, T.3
-
34
-
-
59649109572
-
Antibiotic resistance genes from the environment: A perspective through newly identified antibiotic resistance mechanisms in the clinical setting
-
Cantón R. Antibiotic resistance genes from the environment: a perspective through newly identified antibiotic resistance mechanisms in the clinical setting. Clin Microbiol Infect 2009; 15 Suppl 1: 20–5.
-
(2009)
Clin Microbiol Infect
, vol.15
, pp. 20-25
-
-
Cantón, R.1
-
35
-
-
85030684043
-
MCR-2-mediated plasmid-borne polymyxin resistance most likely originates from Moraxella pluranimalium
-
Poirel L, Kieffer N, Fernandez-Garayzabal JF et al. MCR-2-mediated plasmid-borne polymyxin resistance most likely originates from Moraxella pluranimalium. J Antimicrob Chemother 2017; 72: 2947–9.
-
(2017)
J Antimicrob Chemother
, vol.72
, pp. 2947-2949
-
-
Poirel, L.1
Kieffer, N.2
Fernandez-Garayzabal, J.F.3
-
36
-
-
0018291787
-
Plasmid-mediated b-lactamases of Gram-negative bacteria: Properties and distribution
-
Matthew M. Plasmid-mediated b-lactamases of Gram-negative bacteria: properties and distribution. J Antimicrob Chemother 1979; 5: 349–58.
-
(1979)
J Antimicrob Chemother
, vol.5
, pp. 349-358
-
-
Matthew, M.1
-
37
-
-
0023037790
-
Molecular biology of transposable elements
-
Schmitt R. Molecular biology of transposable elements. J Antimicrob Chemother 1986; 18 Suppl C: 25–34.
-
(1986)
J Antimicrob Chemother
, vol.18
, pp. 25-34
-
-
Schmitt, R.1
-
38
-
-
85001574919
-
The Tn3-family of replicative trans-posons
-
Nicolas E, Lambin M, Dandoy D et al. The Tn3-family of replicative trans-posons. Microbiol Spectr 2015; 3: doi:10.1128/microbiolspec.MDNA3-0060-2014.
-
(2015)
Microbiol Spectr
, vol.3
-
-
Nicolas, E.1
Lambin, M.2
Dandoy, D.3
-
39
-
-
84858278979
-
Fourteen years in resistance
-
Livermore DM. Fourteen years in resistance. Int J Antimicrob Agents 2012;39:283–94.
-
(2012)
Int J Antimicrob Agents
, vol.39
, pp. 283-294
-
-
Livermore, D.M.1
-
40
-
-
84886280390
-
Declining cephalosporin and fluoroquinolone non-susceptibility among bloodstream Enterobacteriaceae from the UK: Links to prescribing change?
-
Livermore DM, Hope R, Reynolds R et al. Declining cephalosporin and fluoroquinolone non-susceptibility among bloodstream Enterobacteriaceae from the UK: links to prescribing change? J Antimicrob Chemother 2013; 68: 2667–74.
-
(2013)
J Antimicrob Chemother
, vol.68
, pp. 2667-2674
-
-
Livermore, D.M.1
Hope, R.2
Reynolds, R.3
-
41
-
-
0026445738
-
Survey of the prevalence of b-lactamases amongst 1000 Gram-negative bacilli isolated consecutively at the Royal London Hospital
-
Liu PY, Gur D, Hall LM et al. Survey of the prevalence of b-lactamases amongst 1000 Gram-negative bacilli isolated consecutively at the Royal London Hospital. J Antimicrob Chemother 1992; 30: 429–47.
-
(1992)
J Antimicrob Chemother
, vol.30
, pp. 429-447
-
-
Liu, P.Y.1
Gur, D.2
Hall, L.M.3
-
44
-
-
84955573617
-
Characterization of the extraintestinal pathogenic Escherichia coli ST131 clone among isolates recovered from urinary and bloodstream infections in the United Kingdom
-
Ciesielczuk H, Doumith M, Hope R et al. Characterization of the extraintestinal pathogenic Escherichia coli ST131 clone among isolates recovered from urinary and bloodstream infections in the United Kingdom. J Med Microbiol 2015; 64: 1496–503.
-
(2015)
J Med Microbiol
, vol.64
, pp. 1496-1503
-
-
Ciesielczuk, H.1
Doumith, M.2
Hope, R.3
-
47
-
-
84856070939
-
Inactivation of the lipopeptide antibiotic daptomycin by hydrolytic mechanisms
-
D’Costa VM, Mukhtar TA, Patel T et al. Inactivation of the lipopeptide antibiotic daptomycin by hydrolytic mechanisms. Antimicrob Agents Chemother 2012; 56: 757–64.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 757-764
-
-
D’Costa, V.M.1
Mukhtar, T.A.2
Patel, T.3
-
48
-
-
0027478123
-
Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes
-
Shaw KJ, Rather PN, Hare RS et al. Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes. Microbiol Rev 1993; 57: 138–63.
-
(1993)
Microbiol Rev
, vol.57
, pp. 138-163
-
-
Shaw, K.J.1
Rather, P.N.2
Hare, R.S.3
-
49
-
-
84991287594
-
Aminoglycoside resistance: The emergence of acquired 16S ribosomal RNA methyltransferases
-
Doi Y, Wachino JI, Arakawa Y. Aminoglycoside resistance: the emergence of acquired 16S ribosomal RNA methyltransferases. Infect Dis Clin North Am 2016; 30: 523–37.
-
(2016)
Infect Dis Clin North Am
, vol.30
, pp. 523-537
-
-
Doi, Y.1
Wachino, J.I.2
Arakawa, Y.3
-
50
-
-
0033994788
-
The biopesticide Paenibacillus popilliae has a vancomycin resistance gene cluster homologous to the enterococcal VanA vancomycin resistance gene cluster
-
Patel R, Piper K, Cockerill FR et al. The biopesticide Paenibacillus popilliae has a vancomycin resistance gene cluster homologous to the enterococcal VanA vancomycin resistance gene cluster. Antimicrob Agents Chemother 2000; 44: 705–9.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 705-709
-
-
Patel, R.1
Piper, K.2
Cockerill, F.R.3
-
51
-
-
25844514318
-
Glycopeptide resistance vanA operons in Paenibacillus strains isolated from soil
-
Guardabassi L, Perichon B, van Heijenoort J et al. Glycopeptide resistance vanA operons in Paenibacillus strains isolated from soil. Antimicrob Agents Chemother 2005; 49: 4227–33.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 4227-4233
-
-
Guardabassi, L.1
Perichon, B.2
Van Heijenoort, J.3
-
52
-
-
0032719566
-
Genetic basis of methicillin resistance in Staphylococcus aureus
-
Berger-Bächi B. Genetic basis of methicillin resistance in Staphylococcus aureus. Cell Mol Life Sci 1999; 56: 764–70.
-
(1999)
Cell Mol Life Sci
, vol.56
, pp. 764-770
-
-
Berger-Bächi, B.1
-
53
-
-
0018575015
-
Affinities of penicillins and cephalosporins for the penicillin-binding proteins of Escherichia coli K-12 and their antibacterial activity
-
Curtis NA, Orr D, Ross GW et al. Affinities of penicillins and cephalosporins for the penicillin-binding proteins of Escherichia coli K-12 and their antibacterial activity. Antimicrob Agents Chemother 1979; 16: 533–9.
-
(1979)
Antimicrob Agents Chemother
, vol.16
, pp. 533-539
-
-
Curtis, N.A.1
Orr, D.2
Ross, G.W.3
-
54
-
-
0021139196
-
Studies on the mechanism of action of imipenem (N-formimidoylthienamycin) in vitro: Binding to the penicillin-binding proteins (PBPs) in Escherichia coli and Pseudomonas aeruginosa, and inhibition of enzyme activities due to the PBPs in E. Coli
-
Hashizume T, Ishino F, Nakagawa J et al. Studies on the mechanism of action of imipenem (N-formimidoylthienamycin) in vitro: binding to the penicillin-binding proteins (PBPs) in Escherichia coli and Pseudomonas aeruginosa, and inhibition of enzyme activities due to the PBPs in E. coli. J Antibiot 1984; 37: 394–400.
-
(1984)
J Antibiot
, vol.37
, pp. 394-400
-
-
Hashizume, T.1
Ishino, F.2
Nakagawa, J.3
-
57
-
-
0025959141
-
Transferable imipenem resistance in Pseudomonas aeruginosa
-
Watanabe M, Iyobe S, Inoue M et al. Transferable imipenem resistance in Pseudomonas aeruginosa. Antimicrob Agents Chemother 1991; 35: 147–51.
-
(1991)
Antimicrob Agents Chemother
, vol.35
, pp. 147-151
-
-
Watanabe, M.1
Iyobe, S.2
Inoue, M.3
-
58
-
-
84875181975
-
Global spread of antibiotic resistance: The example of New Delhi metallo-b-lactamase (NDM)-mediated carbapenem resistance
-
Johnson AP, Woodford N. Global spread of antibiotic resistance: the example of New Delhi metallo-b-lactamase (NDM)-mediated carbapenem resistance. J Med Microbiol 2013; 62: 499–513.
-
(2013)
J Med Microbiol
, vol.62
, pp. 499-513
-
-
Johnson, A.P.1
Woodford, N.2
-
59
-
-
78650636489
-
Activities of NXL104 combinations with ceftazidime and aztreonam against carbapenemase-producing Enterobacteriaceae
-
Livermore DM, Mushtaq S, Warner M et al. Activities of NXL104 combinations with ceftazidime and aztreonam against carbapenemase-producing Enterobacteriaceae. Antimicrob Agents Chemother 2011; 55: 390–4.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 390-394
-
-
Livermore, D.M.1
Mushtaq, S.2
Warner, M.3
-
60
-
-
85020135744
-
In vitro activity of cefepime/ zidebactam (WCK 5222) against Gram-negative bacteria
-
Livermore DM, Mushtaq S, Warner M et al. In vitro activity of cefepime/ zidebactam (WCK 5222) against Gram-negative bacteria. J Antimicrob Chemother 2017; 72: 1373–85.
-
(2017)
J Antimicrob Chemother
, vol.72
, pp. 1373-1385
-
-
Livermore, D.M.1
Mushtaq, S.2
Warner, M.3
-
61
-
-
84957886715
-
Interactionsof OP0595, anovel triple-action diazabicyclooctane, with b-lactams against OP0595-resistant Enterobacteriaceae mutants
-
Livermore DM, Warner M, Mushtaq Setal. Interactionsof OP0595, anovel triple-action diazabicyclooctane, with b-lactams against OP0595-resistant Enterobacteriaceae mutants. Antimicrob Agents Chemother 2015; 60: 554–60.
-
(2015)
Antimicrob Agents Chemother
, vol.60
, pp. 554-560
-
-
Livermore, D.M.1
Warner, M.2
Setal, M.3
-
63
-
-
85061175915
-
Nacubactam (RG6080) alone and in combination against metallo-b-lactamase (MBL)-producing Enterobacteriaceae
-
Madrid, Spain, Poster P1033. ESCMID, Basel, Switzerland
-
Mushtaq S, Vickers A, Woodford N et al. Nacubactam (RG6080) alone and in combination against metallo-b-lactamase (MBL)-producing Enterobacteriaceae. In: Posters of the Twenty-eighth European Congress of Clinical Microbiology and Infectious Diseases, Madrid, Spain, 2018. Poster P1033. ESCMID, Basel, Switzerland.
-
(2018)
Posters of The Twenty-Eighth European Congress of Clinical Microbiology and Infectious Diseases
-
-
Mushtaq, S.1
Vickers, A.2
Woodford, N.3
-
65
-
-
85061181599
-
Potentiation of cefepime by the boronate VNRX-5133 versus Gram-negative bacteria with known b-lactamases
-
Madrid, Spain, Poster P1536. ESCMID, Basel, Switzerland
-
Mushtaq S, Vickers A, Woodford N et al. Potentiation of cefepime by the boronate VNRX-5133 versus Gram-negative bacteria with known b-lactamases. In: Posters of the Twenty-eighth European Congress of Clinical Microbiology and Infectious Diseases, Madrid, Spain, 2018. Poster P1536. ESCMID, Basel, Switzerland.
-
(2018)
Posters of The Twenty-Eighth European Congress of Clinical Microbiology and Infectious Diseases
-
-
Mushtaq, S.1
Vickers, A.2
Woodford, N.3
-
66
-
-
84957895337
-
In vitro antimicrobial activity of a siderophore cephalosporin, S-649266, against Enterobacteriaceae clinical isolates, including carbapenem-resistant strains
-
Kohira N, West J, Ito A et al. In vitro antimicrobial activity of a siderophore cephalosporin, S-649266, against Enterobacteriaceae clinical isolates, including carbapenem-resistant strains. Antimicrob Agents Chemother 2015; 60: 729–34.
-
(2015)
Antimicrob Agents Chemother
, vol.60
, pp. 729-734
-
-
Kohira, N.1
West, J.2
Ito, A.3
-
67
-
-
85040361131
-
Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae – Identification of LYS228
-
Reck F, Bermingham A, Blais J et al. Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae – identification of LYS228. Bioorg Med Chem Lett 2018; 28: 748–55.
-
(2018)
Bioorg Med Chem Lett
, vol.28
, pp. 748-755
-
-
Reck, F.1
Bermingham, A.2
Blais, J.3
-
68
-
-
85049133487
-
The clinical development of antibacterial drugs: A guide for the discovery scientist
-
Fisher JF, Mobashery S, Miller MJ, eds. Berlin, Heidelberg: Springer
-
Shlaes DM. The clinical development of antibacterial drugs: a guide for the discovery scientist. In: Topics in Medicinal Chemistry. Fisher JF, Mobashery S, Miller MJ, eds. Berlin, Heidelberg: Springer, 2018; 149–63.
-
(2018)
Topics in Medicinal Chemistry
, pp. 149-163
-
-
Shlaes, D.M.1
-
69
-
-
85017371968
-
A randomised, double-blind, phase 3 study comparing the efficacy and safety of ceftazidime/avibactam plus metronida-zole versus meropenem for complicated intra-abdominal infections in hospi-talised adults in Asia
-
Qin X, Tran BG, Kim MJ et al. A randomised, double-blind, phase 3 study comparing the efficacy and safety of ceftazidime/avibactam plus metronida-zole versus meropenem for complicated intra-abdominal infections in hospi-talised adults in Asia. Int J Antimicrob Agents 2017; 49: 579–88.
-
(2017)
Int J Antimicrob Agents
, vol.49
, pp. 579-588
-
-
Qin, X.1
Tran, B.G.2
Kim, M.J.3
-
70
-
-
85020131028
-
In vitro activity of ceftazidime/avibactam against urinary isolates from patients in a Phase 3 clinical trial pro-gramme for the treatment of complicated urinary tract infections
-
Stone GG, Bradford PA, Yates K et al. In vitro activity of ceftazidime/avibactam against urinary isolates from patients in a Phase 3 clinical trial pro-gramme for the treatment of complicated urinary tract infections. J Antimicrob Chemother 2017; 72: 1396–9.
-
(2017)
J Antimicrob Chemother
, vol.72
, pp. 1396-1399
-
-
Stone, G.G.1
Bradford, P.A.2
Yates, K.3
-
71
-
-
84963954564
-
Ceftazidime/avibactam or best available therapy in patients with ceftazidime-resistant Enterobacteriaceae and Pseudomonas aeruginosa complicated urinary tract infections or complicated intra-abdominal infections (REPRISE): A randomised, pathogen-directed, phase 3 study
-
Carmeli Y, Armstrong J, Laud PJ et al. Ceftazidime/avibactam or best available therapy in patients with ceftazidime-resistant Enterobacteriaceae and Pseudomonas aeruginosa complicated urinary tract infections or complicated intra-abdominal infections (REPRISE): a randomised, pathogen-directed, phase 3 study. Lancet Infect Dis 2016; 16: 661–73.
-
(2016)
Lancet Infect Dis
, vol.16
, pp. 661-673
-
-
Carmeli, Y.1
Armstrong, J.2
Laud, P.J.3
-
72
-
-
37249044139
-
Orthodox and unorthodox clavulanate combinations against extended-spectrum b-lactamase producers
-
Livermore DM, Hope R, Mushtaq S et al. Orthodox and unorthodox clavulanate combinations against extended-spectrum b-lactamase producers. Clin Microbiol Infect 2008; 14 Suppl 1: 189–93.
-
(2008)
Clin Microbiol Infect
, vol.14
, pp. 189-193
-
-
Livermore, D.M.1
Hope, R.2
Mushtaq, S.3
-
73
-
-
85017035614
-
Antimicrobial activity of high-proportion cefepime/tazobactam (WCK 4282) against a large number of Gram-negative isolates collected worldwide in 2014
-
Sader HS, Castanheira M, Mendes RE et al. Antimicrobial activity of high-proportion cefepime/tazobactam (WCK 4282) against a large number of Gram-negative isolates collected worldwide in 2014. Antimicrob Agents Chemother 2017; 61: e02409-16.
-
(2017)
Antimicrob Agents Chemother
, vol.61
, pp. e02409-e02416
-
-
Sader, H.S.1
Castanheira, M.2
Mendes, R.E.3
-
74
-
-
85040594200
-
Potential of high-dose cefepime/tazobactam against multiresistant Gram-negative pathogens
-
Livermore DM, Mushtaq S, Warner M et al. Potential of high-dose cefepime/tazobactam against multiresistant Gram-negative pathogens. J Antimicrob Chemother 2018; 73: 126–33.
-
(2018)
J Antimicrob Chemother
, vol.73
, pp. 126-133
-
-
Livermore, D.M.1
Mushtaq, S.2
Warner, M.3
-
75
-
-
34247173928
-
Efficacy and safety of cefepime: A systematic review and meta-analysis
-
Yahav D, Paul M, Fraser A et al. Efficacy and safety of cefepime: a systematic review and meta-analysis. Lancet Infect Dis 2007; 7: 338–48.
-
(2007)
Lancet Infect Dis
, vol.7
, pp. 338-348
-
-
Yahav, D.1
Paul, M.2
Fraser, A.3
-
76
-
-
77955682967
-
Meta-analysis of a possible signal of increased mortality associated with cefepime use
-
Kim PW, Wu YT, Cooper C et al. Meta-analysis of a possible signal of increased mortality associated with cefepime use. Clin Infect Dis 2010; 51: 381–9.
-
(2010)
Clin Infect Dis
, vol.51
, pp. 381-389
-
-
Kim, P.W.1
Wu, Y.T.2
Cooper, C.3
-
77
-
-
85033717305
-
Klebsiella pneumoniae carbapenemase-2 (KPC-2), substitutions at Ambler position Asp179, and resistance to ceftazidime/avibactam: Unique antibiotic-resistant phenotypes emerge from b-lactamase protein engineering
-
Barnes MD, Winkler ML, Taracila MA et al. Klebsiella pneumoniae carbapenemase-2 (KPC-2), substitutions at Ambler position Asp179, and resistance to ceftazidime/avibactam: unique antibiotic-resistant phenotypes emerge from b-lactamase protein engineering. MBio 2017; 8: e00528-17.
-
(2017)
MBio
, vol.8
, pp. e00528-e00617
-
-
Barnes, M.D.1
Winkler, M.L.2
Taracila, M.A.3
-
78
-
-
85043332988
-
Activity of ceftazidime/avibactam against problem Enterobacteriaceae and Pseudomonas aeruginosa in the UK, 2015–16
-
Livermore DM, Meunier D, Hopkins KL et al. Activity of ceftazidime/avibactam against problem Enterobacteriaceae and Pseudomonas aeruginosa in the UK, 2015–16. J Antimicrob Chemother 2017; 73: 648–57.
-
(2017)
J Antimicrob Chemother
, vol.73
, pp. 648-657
-
-
Livermore, D.M.1
Meunier, D.2
Hopkins, K.L.3
-
79
-
-
84983593578
-
Successful treatment of bloodstream infection due to metallo-b-lactamase-producing Stenotrophomonas maltophilia in a renal transplant patient
-
Mojica MF, Ouellette CP, Leber A et al. Successful treatment of bloodstream infection due to metallo-b-lactamase-producing Stenotrophomonas maltophilia in a renal transplant patient. Antimicrob Agents Chemother 2016; 60: 5130–4.
-
(2016)
Antimicrob Agents Chemother
, vol.60
, pp. 5130-5134
-
-
Mojica, M.F.1
Ouellette, C.P.2
Leber, A.3
-
80
-
-
85028284880
-
Ceftazidime/avibactam and aztreonam, an interesting strategy to overcome b-lactam resistance conferred by metallo-b-lactamases in Enterobacteriaceae and Pseudomonas aeruginosa
-
Davido B, Fellous L, Lawrence C et al. Ceftazidime/avibactam and aztreonam, an interesting strategy to overcome b-lactam resistance conferred by metallo-b-lactamases in Enterobacteriaceae and Pseudomonas aeruginosa. Antimicrob Agents Chemother 2017; 61: e01008-17.
-
(2017)
Antimicrob Agents Chemother
, vol.61
, pp. e01008-e01017
-
-
Davido, B.1
Fellous, L.2
Lawrence, C.3
-
82
-
-
13844311296
-
Colistin treatment in patients with ICU-acquired infections caused by multiresistant Gram-negative bacteria: The renaissance of an old antibiotic
-
Michalopoulos AS, Tsiodras S, Rellos K et al. Colistin treatment in patients with ICU-acquired infections caused by multiresistant Gram-negative bacteria: the renaissance of an old antibiotic. Clin Microbiol Infect 2005; 11: 115–21.
-
(2005)
Clin Microbiol Infect
, vol.11
, pp. 115-121
-
-
Michalopoulos, A.S.1
Tsiodras, S.2
Rellos, K.3
-
84
-
-
85034077858
-
Enhancing the role of vaccines in combatting antimicrobial resistance
-
Clift C, Salisbury DM. Enhancing the role of vaccines in combatting antimicrobial resistance. Vaccine 2017; 35: 6591–3.
-
(2017)
Vaccine
, vol.35
, pp. 6591-6593
-
-
Clift, C.1
Salisbury, D.M.2
-
85
-
-
85013648004
-
Safety, immunogenicity, and preliminary clinical efficacy of a vaccine against extraintestinal pathogenic Escherichia coli in women with a history of recurrent urinary tract infection: A randomised, single-blind, placebo-controlled phase 1b trial
-
Huttner A, Hatz C, van den Dobbelsteen G et al. Safety, immunogenicity, and preliminary clinical efficacy of a vaccine against extraintestinal pathogenic Escherichia coli in women with a history of recurrent urinary tract infection: a randomised, single-blind, placebo-controlled phase 1b trial. Lancet Infect Dis 2017; 17: 528–37.
-
(2017)
Lancet Infect Dis
, vol.17
, pp. 528-537
-
-
Huttner, A.1
Hatz, C.2
van den Dobbelsteen, G.3
-
86
-
-
84957637760
-
Alternatives to antibiotics—a pipeline portfolio review
-
Czaplewski L, Bax R, Clokie M et al. Alternatives to antibiotics—a pipeline portfolio review. Lancet Infect Dis 2016; 16: 239–51.
-
(2016)
Lancet Infect Dis
, vol.16
, pp. 239-251
-
-
Czaplewski, L.1
Bax, R.2
Clokie, M.3
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