Do probiotics, prebiotics and synbiotics affect adiponectin and leptin in adults? A systematic review and meta-analysis of clinical trials

Clinical Nutrition

Volumn 38, Issue 5, 2019, Pages 2031-2037

  Rouhani, Mohammad Hossein ^a   Hadi, Amir ^a   Ghaedi, Ehsan ^b   Salehi, Mina ^a   Mahdavi, Atena ^a   Mohammadi, Hamed ^c  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Adiponectin; Leptin; Meta analysis; Prebiotics; Probiotics; Synbiotics

Indexed keywords

ADIPONECTIN; FRUCTOSE OLIGOSACCHARIDE; LEPTIN; PREBIOTIC AGENT; PROBIOTIC AGENT; SYNBIOTIC AGENT; ADIPOQ PROTEIN, HUMAN; LEP PROTEIN, HUMAN;

ARTICLE; BIFIDOBACTERIUM; BIFIDOBACTERIUM ANIMALIS; BIFIDOBACTERIUM BIFIDUM; BIFIDOBACTERIUM BREVE; BIFIDOBACTERIUM LONGUM; DRUG EFFECT; HORMONE BLOOD LEVEL; HUMAN; LACTOBACILLUS ACIDOPHILUS; LACTOBACILLUS CASEI; LACTOBACILLUS DELBRUECKII SUBSP. BULGARICUS; LACTOBACILLUS GASSERI; LACTOBACILLUS PLANTARUM; LACTOBACILLUS REUTERI; LACTOBACILLUS RHAMNOSUS; META ANALYSIS; MORBID OBESITY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; OBESITY; PROSTATE CANCER; PROTEIN BLOOD LEVEL; STREPTOCOCCUS THERMOPHILUS; SUPPLEMENTATION; SYSTEMATIC REVIEW; ADULT; BLOOD;

ADIPONECTIN; ADULT; HUMANS; LEPTIN; PREBIOTICS; PROBIOTICS; SYNBIOTICS;

EID: 85055085726     PISSN: 02615614     EISSN: 15321983     Source Type: Journal    
DOI: 10.1016/j.clnu.2018.09.033     Document Type: Article

References (38)

1. Trayhurn, P., Wood, I.S., Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr 92:3 (2004), 347–355.
2. Trayhurn, P., Beattie, J.H., Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ. Proc Nutr Soc 60:3 (2001), 329–339.
3. Yadav, A., Kataria, M.A., Saini, V., Yadav, A., Role of leptin and adiponectin in insulin resistance. Clin Chim Acta 417 (2013), 80–84.
4. Barb, D., Pazaitou-Panayiotou, K., Mantzoros, C.S., Adiponectin: a link between obesity and cancer. Expet Opin Invest Drugs 15:8 (2006), 917–931.
5. Hotta, K., Funahashi, T., Arita, Y., Takahashi, M., Matsuda, M., Okamoto, Y., et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 20:6 (2000), 1595–1599.
6. Yang, W.-S., Lee, W.-J., Funahashi, T., Tanaka, S., Matsuzawa, Y., Chao, C.-L., et al. Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. J Clin Endocrinol Metab 86:8 (2001), 3815–3819.
7. Kelesidis, T., Kelesidis, I., Chou, S., Mantzoros, C.S., Narrative review: the role of leptin in human physiology: emerging clinical applications. Ann Intern Med 152:2 (2010), 93–100.
8. Kuryszko, J., Sławuta, P., Sapikowski, G., Secretory function of adipose tissue. Pol J Vet Sci 19:2 (2016), 441–446.
9. Sekirov, I., Russell, S.L., Antunes, L.C.M., Finlay, B.B., Gut microbiota in health and disease. Physiol Rev 90:3 (2010), 859–904.
10. Walker, A.W., Lawley, T.D., Therapeutic modulation of intestinal dysbiosis. Pharmacol Res 69:1 (2013), 75–86.
11. Kootte, R., Vrieze, A., Holleman, F., Dallinga-Thie, G.M., Zoetendal, E.G., de Vos, W.M., et al. The therapeutic potential of manipulating gut microbiota in obesity and type 2 diabetes mellitus. Diabetes Obes Metabol 14:2 (2012), 112–120.
12. Schrezenmeir, J., de Vrese, M., Probiotics, prebiotics, and synbiotics—approaching a definition. Am J Clin Nutr 73:2 (2001), 361s–364s.
13. Gibson, G.R., Hutkins, R., Sanders, M.E., Prescott, S.L., Reimer, R.A., Salminen, S.J., et al. Expert consensus document: the International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics. Nat Rev Gastroenterol Hepatol, 14(8), 2017, 491.
14. Sanz, Y., Santacruz, A., Gauffin, P., Gut microbiota in obesity and metabolic disorders. Proc Nutr Soc 69:3 (2010), 434–441.
15. Al-muzafar, H.M., Amin, K.A., Probiotic mixture improves fatty liver disease by virtue of its action on lipid profiles, leptin, and inflammatory biomarkers. BMC Complement Altern Med, 17(1), 2017, 43.
16. Kim, S.-W., Park, K.-Y., Kim, B., Kim, E., Hyun, C.-K., Lactobacillus rhamnosus GG improves insulin sensitivity and reduces adiposity in high-fat diet-fed mice through enhancement of adiponectin production. Biochem Biophys Res Commun 431:2 (2013), 258–263.
17. Behrouz, V., Jazayeri, S., Aryaeian, N., Zahedi, M.J., Hosseini, F., Effects of probiotic and prebiotic supplementation on leptin, adiponectin, and glycemic parameters in non-alcoholic fatty liver disease: a randomized clinical trial. Middle East J Dig Dis, 9(3), 2017, 150.
18. Feizollahzadeh, S., Ghiasvand, R., Rezaei, A., Khanahmad, H., Hariri, M., Effect of probiotic soy milk on serum levels of adiponectin, inflammatory mediators, lipid profile, and fasting blood glucose among patients with type II diabetes mellitus. Probiotics Antimicrob Proteins 9:1 (2017), 41–47.
19. Picot, J., Hartwell, D., Harris, P., Mendes, D., Clegg, A., Takeda, A., The preferred reporting items for systematic reviews and meta-analyses checklist. 2012.
20. Jadad, A.R., Moore, R.A., Carroll, D., Jenkinson, C., Reynolds, D.J.M., Gavaghan, D.J., et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary?. Contr Clin Trials 17:1 (1996), 1–12.
21. Ekhlasi, G., Mohammadi, R.K., Agah, S., Zarrati, M., Hosseini, A.F., Arabshahi, S.S.S., et al. Do symbiotic and vitamin E supplementation have favorite effects in nonalcoholic fatty liver disease? A randomized, double-blind, placebo-controlled trial. J Res Med Sci Off J Isfahan Univ Med Sci, 21, 2016.
22. Gomes, A.C., de Sousa, R.G.M., Botelho, P.B., Gomes, T.L.N., Prada, P.O., Mota, J.F., The additional effects of a probiotic mix on abdominal adiposity and antioxidant status: a double-blind, randomized trial. Obesity 25:1 (2017), 30–38.
23. Kadooka, Y., Sato, M., Imaizumi, K., Ogawa, A., Ikuyama, K., Akai, Y., et al. Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial. Eur J Clin Nutr, 64(6), 2010, 636.
24. McMullen, M.H., Hamilton-Reeves, J.M., Bonorden, M.J., Wangen, K.E., Phipps, W.R., Feirtag, J.M., et al. Consumption of Lactobacillus acidophilus and Bifidobacterium longum does not alter phytoestrogen metabolism and plasma hormones in men: a pilot study. J Altern Compl Med 12:9 (2006), 887–894.
25. Mobini, R., Tremaroli, V., Ståhlman, M., Karlsson, F., Levin, M., Ljungberg, M., et al. Metabolic effects of Lactobacillus reuteri DSM 17938 in people with type 2 diabetes: a randomized controlled trial. Diabetes Obes Metabol 19:4 (2017), 579–589.
26. Parnell, J.A., Klancic, T., Reimer, R.A., Oligofructose decreases serum lipopolysaccharide and plasminogen activator inhibitor-1 in adults with overweight/obesity. Obesity 25:3 (2017), 510–513.
27. Tonucci, L.B., dos Santos, K.M.O., de Oliveira, L.L., Ribeiro, S.M.R., Martino, H.S.D., Clinical application of probiotics in type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled study. Clin Nutr 36:1 (2017), 85–92.
28. Zarrati, M., Salehi, E., Nourijelyani, K., Mofid, V., Zadeh, M.J.H., Najafi, F., et al. Effects of probiotic yogurt on fat distribution and gene expression of proinflammatory factors in peripheral blood mononuclear cells in overweight and obese people with or without weight-loss diet. J Am Coll Nutr 33:6 (2014), 417–425.
29. Sherf-Dagan, S., Zelber-Sagi, S., Zilberman-Schapira, G., Webb, M., Buch, A., Keidar, A., et al. Probiotics administration following sleeve gastrectomy surgery: a randomized double-blind trial. Int J Obes, 42(2), 2018, 147.
30. Nabavi, S., Rafraf, M., Somi, M.-h., Homayouni-Rad, A., Asghari-Jafarabadi, M., Probiotic yogurt improves body mass index and fasting insulin levels without affecting serum leptin and adiponectin levels in non-alcoholic fatty liver disease (NAFLD). J Funct Foods 18 (2015), 684–691.
31. Mamaghani, F., Zarghami, N., Maleki, M., Pourhassan-Moghaddam, M., Hosseinpanah, F., Variation of adiponectin levels in normal and obese subjects: possible correlation with lipid profiles. Int J Endocrinol Metabol 3 (2009), 170–178.
32. Cho, Y.A., Kim, J., Effect of probiotics on blood lipid concentrations: a meta-analysis of randomized controlled trials. Medicine, 94(43), 2015.
33. Wu, Y., Zhang, Q., Ren, Y., Ruan, Z., Effect of probiotic Lactobacillus on lipid profile: a systematic review and meta-analysis of randomized, controlled trials. PLoS One, 12(6), 2017, e0178868.
34. Kawano, J., Arora, R., The role of adiponectin in obesity, diabetes, and cardiovascular disease. J Cardiometab Syndr 4:1 (2009), 44–49.
35. Borgeraas, H., Johnson, L., Skattebu, J., Hertel, J., Hjelmesæth, J., Effects of probiotics on body weight, body mass index, fat mass and fat percentage in subjects with overweight or obesity: a systematic review and meta-analysis of randomized controlled trials. Obes Rev 19:2 (2018), 219–232.
36. Xiong, Y., Miyamoto, N., Shibata, K., Valasek, M.A., Motoike, T., Kedzierski, R.M., et al. Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc Natl Acad Sci U S A 101:4 (2004), 1045–1050.
37. Roberfroid, M., Gibson, G.R., Hoyles, L., McCartney, A.L., Rastall, R., Rowland, I., et al. Prebiotic effects: metabolic and health benefits. Br J Nutr 104:S2 (2010), S1–S63.
38. Kolida, S., Gibson, G.R., Synbiotics in health and disease. Ann Rev Food Sci Technol 2 (2011), 373–393.