CD4+T cells mediate protection against Zika associated severe disease in a mouse model of infection

PLoS Pathogens

Volumn 14, Issue 9, 2018, Pages

  Hassert, Mariah ^a   Wolf, Kyle J ^a   Schwetye, Katherine E ^a   DiPaolo, Richard J ^a   Brien, James D ^a   Pinto, Amelia K ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BETA INTERFERON RECEPTOR; GAMMA INTERFERON; POLYPROTEIN; T LYMPHOCYTE RECEPTOR; EPITOPE; IFNAR1 PROTEIN, MOUSE; VIRUS ANTIGEN; VIRUS VACCINE;

ADAPTIVE IMMUNITY; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL PROTECTION; CELLULAR IMMUNITY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENETIC VARIABILITY; HISTOLOGY; HUMORAL IMMUNITY; IMMUNE RESPONSE; MOUSE; NONHUMAN; PEPTIDE LIBRARY; POLYMERASE CHAIN REACTION; T CELL DEPLETION; T LYMPHOCYTE; T-CELL GENE REARRANGEMENT; VIREMIA; VIRUS INFECTION; VIRUS LOAD; VIRUS TITRATION; ZIKA FEVER; ZIKA VIRUS; ADOPTIVE TRANSFER; ANIMAL; C57BL MOUSE; DEFICIENCY; DISEASE MODEL; GENETICS; HUMAN; IMMUNOLOGY; KNOCKOUT MOUSE; LIVER; LYMPHOCYTE DEPLETION; PATHOGENICITY; T LYMPHOCYTE RECEPTOR GENE; VIROLOGY; VIRUS REPLICATION;

ADOPTIVE TRANSFER; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, VIRAL; CD4-POSITIVE T-LYMPHOCYTES; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; EPITOPES, T-LYMPHOCYTE; GENES, T-CELL RECEPTOR BETA; HUMANS; IMMUNITY, CELLULAR; LIVER; LYMPHOCYTE DEPLETION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTOR, INTERFERON ALPHA-BETA; VIRAL VACCINES; VIRUS REPLICATION; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85054557123     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1007237     Document Type: Article

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