Joint profiling of chromatin accessibility and gene expression in thousands of single cells

Science

Volumn 361, Issue 6409, 2018, Pages 1380-1385

  Cao, Junyue ^a   Cusanovich, Darren A ^a,g   Ramani, Vijay ^a   Aghamirzaie, Delasa ^a   Pliner, Hannah A ^a   Hill, Andrew J ^a   Daza, Riza M ^a   McFaline Figueroa, Jose L ^a   Packer, Jonathan S ^a   Christiansen, Lena ^b   Steemers, Frank J ^b   Adey, Andrew C ^c,d   Trapnell, Cole ^a,e,f   Shendure, Jay ^a,e,f  

^a UNIVERSITY OF WASHINGTON   (United States)

^b ILLUMINA INC   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^e Allen Discovery Center for Cell Lineage Tracing   (United States)

^f BROTMAN BATY INSTITUTE FOR PRECISION MEDICINE   (United States)

^g UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DEOXYRIBONUCLEASE; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; PER1 PROTEIN; PROTEIN TN5; SODIUM CHLORIDE COTRANSPORTER; TRANSPOSASE; UNCLASSIFIED DRUG;

BIOASSAY; BIOLOGY; CELL COMPONENT; GENE; GENE EXPRESSION; RNA;

A-549 CELL LINE; ADIPOCYTE; ARTICLE; CDH16 GENE; CELL PROLIFERATION; CELL SUBPOPULATION; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CKB GENE; CORRELATIONAL STUDY; DNA CONFORMATION; DNA SEQUENCE; DNA SYNTHESIS; ENZYME ACTIVATION; EPIGENETICS; GENE; GENE AMPLIFICATION; GENE EXPRESSION; GENE SEQUENCE; GENE TARGETING; GENETIC LINKAGE; GENETIC TRANSCRIPTION; GENOMIC IN SITU HYBRIDIZATION; HEK293T CELL LINE; HUMAN; KIDNEY FUNCTION; KIDNEY TISSUE; KIDNEY TUBULE ABSORPTION; KLF9 GENE; MARKER GENE; NFKBIA GENE; NIH 3T3 CELL LINE; NONHUMAN; PER1 GENE; PERICYTE; PHENOTYPE; POSITIVE FEEDBACK; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; PROOF OF CONCEPT; REGULATORY SEQUENCE; REVERSE TRANSCRIPTION; RNA ANALYSIS; RNA SEQUENCE; SCHNEIDER 3 CELL LINE; SCNN1A GENE; SINGLE CELL ANALYSIS; SLC12A3 GENE; TRANSCRIPTOMICS; ANIMAL; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOMICS; HEK293 CELL LINE; KIDNEY; METABOLISM; MOUSE; PROCEDURES;

A549 CELLS; ANIMALS; CHROMATIN; DEXAMETHASONE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOMICS; HEK293 CELLS; HUMANS; KIDNEY; MICE; NIH 3T3 CELLS; REGULATORY ELEMENTS, TRANSCRIPTIONAL; SINGLE-CELL ANALYSIS; TRANSCRIPTION, GENETIC;

EID: 85054154765     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aau0730     Document Type: Article

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