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Volumn 6, Issue 9, 2018, Pages 1039-1045

Improved risk-adjusted survival for melanoma brain metastases in the era of checkpoint blockade immunotherapies: Results from a national cohort

Author keywords

[No Author keywords available]

Indexed keywords

IPILIMUMAB; VEMURAFENIB;

EID: 85052890127     PISSN: 23266066     EISSN: 23266074     Source Type: Journal    
DOI: 10.1158/2326-6066.CIR-18-0067     Document Type: Article
Times cited : (57)

References (39)
  • 3
    • 34548259259 scopus 로고    scopus 로고
    • Multidisciplinary management of brain metastases
    • Eichler AF, Loeffler JS. Multidisciplinary management of brain metastases. Oncologist 2007;12:884–98.
    • (2007) Oncologist , vol.12 , pp. 884-898
    • Eichler, A.F.1    Loeffler, J.S.2
  • 4
  • 5
    • 84886443514 scopus 로고    scopus 로고
    • CTLA-4 and PD-1/PD-L1 blockade: New immunotherapeutic modalities with durable clinical benefit in melanoma patients
    • Ott PA, Hodi FS, Robert C. CTLA-4 and PD-1/PD-L1 blockade: new immunotherapeutic modalities with durable clinical benefit in melanoma patients. Clin Cancer Res 2013;19:5300–9.
    • (2013) Clin Cancer Res , vol.19 , pp. 5300-5309
    • Ott, P.A.1    Hodi, F.S.2    Robert, C.3
  • 9
    • 85011542577 scopus 로고    scopus 로고
    • Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial
    • Hodi FS, Chesney J, Pavlick AC, Robert C, Grossmann KF, McDermott DF, et al. Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial. Lancet Oncol 2016;17: 1558–68.
    • (2016) Lancet Oncol , vol.17 , pp. 1558-1568
    • Hodi, F.S.1    Chesney, J.2    Pavlick, A.C.3    Robert, C.4    Grossmann, K.F.5    McDermott, D.F.6
  • 10
    • 85012115778 scopus 로고    scopus 로고
    • Immune checkpoint inhibitors and targeted therapies for metastatic melanoma: A network meta-analysis
    • Pasquali S, Chiarion-Sileni V, Rossi CR, Mocellin S. Immune checkpoint inhibitors and targeted therapies for metastatic melanoma: a network meta-analysis. Cancer Treat Rev 2017;54:34–42.
    • (2017) Cancer Treat Rev , vol.54 , pp. 34-42
    • Pasquali, S.1    Chiarion-Sileni, V.2    Rossi, C.R.3    Mocellin, S.4
  • 13
    • 84908354848 scopus 로고    scopus 로고
    • Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: A randomised dose-comparison cohort of a phase 1 trial
    • Robert C, Ribas A, Wolchok JD, Hodi FS, Hamid O, Kefford R, et al. Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet 2014;384:1109–17.
    • (2014) Lancet , vol.384 , pp. 1109-1117
    • Robert, C.1    Ribas, A.2    Wolchok, J.D.3    Hodi, F.S.4    Hamid, O.5    Kefford, R.6
  • 17
    • 84860446616 scopus 로고    scopus 로고
    • Ipilimumab in patients with melanoma and brain metastases: An open-label, phase 2 trial
    • Margolin K, Ernstoff MS, Hamid O, Lawrence D, McDermott D, Puzanov I, et al. Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial. Lancet Oncol 2012;13:459–65.
    • (2012) Lancet Oncol , vol.13 , pp. 459-465
    • Margolin, K.1    Ernstoff, M.S.2    Hamid, O.3    Lawrence, D.4    McDermott, D.5    Puzanov, I.6
  • 18
    • 84971619894 scopus 로고    scopus 로고
    • Pembrolizumab for patients with melanoma or non-small-cell lung cancer and untreated brain metastases: Early analysis of a non-randomised, open-label, phase 2 trial
    • Goldberg SB, Gettinger SN, Mahajan A, Chiang AC, Herbst RS, Sznol M, et al. Pembrolizumab for patients with melanoma or non-small-cell lung cancer and untreated brain metastases: early analysis of a non-randomised, open-label, phase 2 trial. Lancet Oncol 2016;17:976–83.
    • (2016) Lancet Oncol , vol.17 , pp. 976-983
    • Goldberg, S.B.1    Gettinger, S.N.2    Mahajan, A.3    Chiang, A.C.4    Herbst, R.S.5    Sznol, M.6
  • 19
    • 85027116426 scopus 로고    scopus 로고
    • Efficacy and safety of nivolumab (NIVO) plus ipilimumab (IPI) in patients with melanoma (MEL) metastatic to the brain: Results of the phase II study CheckMate 204
    • Tawbi HA-H, Forsyth PAJ, Algazi AP, Hamid O, Hodi FS, Moschos SJ, et al. Efficacy and safety of nivolumab (NIVO) plus ipilimumab (IPI) in patients with melanoma (MEL) metastatic to the brain: results of the phase II study CheckMate 204. J Clin Oncol 2017;35:9507–9507.
    • (2017) J Clin Oncol , vol.35 , pp. 9507
    • Tawbi, H.A.-H.1    Forsyth, P.A.J.2    Algazi, A.P.3    Hamid, O.4    Hodi, F.S.5    Moschos, S.J.6
  • 20
    • 85027098970 scopus 로고    scopus 로고
    • A randomized phase II study of nivolumab or nivolumab combined with ipilimumab in patients (pts) with melanoma brain metastases (mets): The anti-PD1 brain collaboration (ABC)
    • Long GV, Atkinson V, Menzies AM, Lo S, Guminski AD, Brown MP, et al. A randomized phase II study of nivolumab or nivolumab combined with ipilimumab in patients (pts) with melanoma brain metastases (mets): the anti-PD1 brain collaboration (ABC). J Clin Oncol 2017.
    • (2017) J Clin Oncol
    • Long, G.V.1    Atkinson, V.2    Menzies, A.M.3    Lo, S.4    Guminski, A.D.5    Brown, M.P.6
  • 22
    • 84994499942 scopus 로고    scopus 로고
    • Cobimetinib combined with vemurafenib in advanced BRAF(V600)-mutant melanoma (coBRIM): Updated efficacy results from a randomised, double-blind, phase 3 trial
    • Ascierto PA, McArthur GA, Dreno B, Atkinson V, Liszkay G, Di Giacomo AM, et al. Cobimetinib combined with vemurafenib in advanced BRAF(V600)-mutant melanoma (coBRIM): updated efficacy results from a randomised, double-blind, phase 3 trial. Lancet Oncol 2016;17:1248–60.
    • (2016) Lancet Oncol , vol.17 , pp. 1248-1260
    • Ascierto, P.A.1    McArthur, G.A.2    Dreno, B.3    Atkinson, V.4    Liszkay, G.5    Di Giacomo, A.M.6
  • 24
    • 84959919017 scopus 로고    scopus 로고
    • Clinical outcomes of melanoma brain metastases treated with stereotactic radiation and anti-PD-1 therapy
    • Ahmed KA, Stallworth DG, Kim Y, Johnstone PAS, Harrison LB, Caudell JJ, et al. Clinical outcomes of melanoma brain metastases treated with stereotactic radiation and anti-PD-1 therapy. Ann Oncol 2016;27:434–41.
    • (2016) Ann Oncol , vol.27 , pp. 434-441
    • Ahmed, K.A.1    Stallworth, D.G.2    Kim, Y.3    Johnstone, P.A.S.4    Harrison, L.B.5    Caudell, J.J.6
  • 25
    • 84897458716 scopus 로고    scopus 로고
    • Vemurafenib in patients with BRAFV600 mutated metastatic melanoma: An open-label, multicentre, safety study
    • Larkin J, Del Vecchio M, Ascierto PA, Krajsova I, Schachter J, Neyns B, et al. Vemurafenib in patients with BRAFV600 mutated metastatic melanoma: an open-label, multicentre, safety study. Lancet Oncol 2014;15:436–44.
    • (2014) Lancet Oncol , vol.15 , pp. 436-444
    • Larkin, J.1    Del Vecchio, M.2    Ascierto, P.A.3    Krajsova, I.4    Schachter, J.5    Neyns, B.6
  • 26
    • 84868120907 scopus 로고    scopus 로고
    • Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): A multicentre, open-label, phase 2 trial
    • Long GV, Trefzer U, Davies MA, Kefford RF, Ascierto PA, Chapman PB, et al. Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial. Lancet Oncol 2012;13:1087–95.
    • (2012) Lancet Oncol , vol.13 , pp. 1087-1095
    • Long, G.V.1    Trefzer, U.2    Davies, M.A.3    Kefford, R.F.4    Ascierto, P.A.5    Chapman, P.B.6
  • 28
    • 85031505743 scopus 로고    scopus 로고
    • Melanoma brain metastases treated with stereotactic radiosurgery and concurrent pembrolizumab display marked regression; efficacy and safety of combined treatment
    • Anderson ES, Postow MA, Wolchok JD, Young RJ, Ballangrud Å, Chan TA, et al. Melanoma brain metastases treated with stereotactic radiosurgery and concurrent pembrolizumab display marked regression; efficacy and safety of combined treatment. J Immunother Cancer 2017;5:76.
    • (2017) J Immunother Cancer , vol.5 , pp. 76
    • Anderson, E.S.1    Postow, M.A.2    Wolchok, J.D.3    Young, R.J.4    Ballangrud, Å.5    Chan, T.A.6
  • 29
    • 84988879439 scopus 로고    scopus 로고
    • Ipilimumab and stereotactic radiosurgery versus stereotactic radiosurgery alone for newly diagnosed melanoma brain metastases
    • Patel KR, Shoukat S, Oliver DE, Chowdhary M, Rizzo M, Lawson DH, et al. Ipilimumab and stereotactic radiosurgery versus stereotactic radiosurgery alone for newly diagnosed melanoma brain metastases. Am J Clin Oncol 2015;40:444–50.
    • (2015) Am J Clin Oncol , vol.40 , pp. 444-450
    • Patel, K.R.1    Shoukat, S.2    Oliver, D.E.3    Chowdhary, M.4    Rizzo, M.5    Lawson, D.H.6
  • 30
    • 85027692650 scopus 로고    scopus 로고
    • Phase 1 study of ipilimumab combined with whole brain radiation therapy or radiosurgery for melanoma patients with brain metastases
    • Williams NL, Wuthrick EJ, Kim H, Palmer JD, Garg S, Eldredge-Hindy H, et al. Phase 1 study of ipilimumab combined with whole brain radiation therapy or radiosurgery for melanoma patients with brain metastases. Int J Radiat Oncol Biol Phys 2017;99:22–30.
    • (2017) Int J Radiat Oncol Biol Phys , vol.99 , pp. 22-30
    • Williams, N.L.1    Wuthrick, E.J.2    Kim, H.3    Palmer, J.D.4    Garg, S.5    Eldredge-Hindy, H.6
  • 31
    • 84928938600 scopus 로고    scopus 로고
    • Stereotactic radiosurgery for melanoma brain metastases in patients receiving ipilimumab: Safety profile and efficacy of combined treatment
    • Kiess AP, Wolchok JD, Barker CA, Postow MA, Tabar V, Huse JT, et al. Stereotactic radiosurgery for melanoma brain metastases in patients receiving ipilimumab: safety profile and efficacy of combined treatment. Int J Radiat Oncol 2015;92:368–75.
    • (2015) Int J Radiat Oncol , vol.92 , pp. 368-375
    • Kiess, A.P.1    Wolchok, J.D.2    Barker, C.A.3    Postow, M.A.4    Tabar, V.5    Huse, J.T.6
  • 32
    • 84877043331 scopus 로고    scopus 로고
    • Ipilimumab in melanoma with limited brain metastases treated with stereotactic radiosurgery
    • Mathew M, Tam M, Ott PA, Pavlick AC, Rush SC, Donahue BR, et al. Ipilimumab in melanoma with limited brain metastases treated with stereotactic radiosurgery. Melanoma Res 2013;23:191–5.
    • (2013) Melanoma Res , vol.23 , pp. 191-195
    • Mathew, M.1    Tam, M.2    Ott, P.A.3    Pavlick, A.C.4    Rush, S.C.5    Donahue, B.R.6
  • 35
    • 85044149736 scopus 로고    scopus 로고
    • Immunotherapy and symptomatic radiation necrosis in patients with brain metastases treated with stereotactic radiation
    • Martin AM, Cagney DN, Catalano PJ, Alexander BM, Redig AJ, Schoenfeld JD, et al. Immunotherapy and symptomatic radiation necrosis in patients with brain metastases treated with stereotactic radiation. JAMA Oncol 2018.
    • (2018) JAMA Oncol
    • Martin, A.M.1    Cagney, D.N.2    Catalano, P.J.3    Alexander, B.M.4    Redig, A.J.5    Schoenfeld, J.D.6
  • 36
    • 85019251771 scopus 로고    scopus 로고
    • Radiation necrosis with stereotactic radiosurgery combined with CTLA-4 blockade and PD-1 inhibition for treatment of intracranial disease in metastatic melanoma
    • Fang P, Jiang W, Allen P, Glitza I, Guha N, Hwu P, et al. Radiation necrosis with stereotactic radiosurgery combined with CTLA-4 blockade and PD-1 inhibition for treatment of intracranial disease in metastatic melanoma. J Neurooncol 2017;133:595–602.
    • (2017) J Neurooncol , vol.133 , pp. 595-602
    • Fang, P.1    Jiang, W.2    Allen, P.3    Glitza, I.4    Guha, N.5    Hwu, P.6
  • 37
    • 85042106983 scopus 로고    scopus 로고
    • The impact of timing of immunotherapy with cranial irradiation in melanoma patients with brain metastases: Intracranial progression, survival and toxicity
    • Rahman R, Cortes A, Niemierko A, Oh KS, Flaherty KT, Lawrence DP, et al. The impact of timing of immunotherapy with cranial irradiation in melanoma patients with brain metastases: intracranial progression, survival and toxicity. J Neurooncol 2018.
    • (2018) J Neurooncol
    • Rahman, R.1    Cortes, A.2    Niemierko, A.3    Oh, K.S.4    Flaherty, K.T.5    Lawrence, D.P.6
  • 38
    • 84986290400 scopus 로고    scopus 로고
    • Activity and safety of radiotherapy with anti-PD-1 drug therapy in patients with metastatic melanoma
    • Liniker E, Menzies AM, Kong BY, Cooper A, Ramanujam S, Lo S, et al. Activity and safety of radiotherapy with anti-PD-1 drug therapy in patients with metastatic melanoma. OncoImmunology 2016;5:e1214788.
    • (2016) OncoImmunology , vol.5 , pp. e1214788
    • Liniker, E.1    Menzies, A.M.2    Kong, B.Y.3    Cooper, A.4    Ramanujam, S.5    Lo, S.6
  • 39
    • 79955876849 scopus 로고    scopus 로고
    • Stereotactic radiosurgery for brain metastases: Analysis of outcome and risk of brain radionecrosis
    • Minniti G, Clarke E, Lanzetta G, Osti M, Trasimeni G, Bozzao A, et al. Stereotactic radiosurgery for brain metastases: analysis of outcome and risk of brain radionecrosis. Radiat Oncol 2011;6:48.
    • (2011) Radiat Oncol , vol.6 , pp. 48
    • Minniti, G.1    Clarke, E.2    Lanzetta, G.3    Osti, M.4    Trasimeni, G.5    Bozzao, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.