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Volumn 21, Issue 9, 2018, Pages 1185-1195

Transcriptomic and morphophysiological evidence for a specialized human cortical GABAergic cell type

(34)  Boldog, Eszter a   Bakken, Trygve E b   Hodge, Rebecca D b   Novotny, Mark c   Aevermann, Brian D c   Baka, Judith a   Bordé, Sándor a   Close, Jennie L b   Diez Fuertes, Francisco c   Ding, Song Lin b   Faragó, Nóra a   Kocsis, Ágnes K a   Kovács, Balázs a   Maltzer, Zoe b   McCorrison, Jamison M c   Miller, Jeremy A b   Molnár, Gábor a   Oláh, Gáspár a   Ozsvár, Attila a   Rózsa, Márton a   more..


Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; CALRETININ; CANNABINOID 1 RECEPTOR; CHOLECYSTOKININ; GLUTAMATE DECARBOXYLASE; MOLECULAR MARKER; NUCLEAR RNA; PARVALBUMIN; SOMATOSTATIN; RNA; TRANSCRIPTOME;

EID: 85052700215     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/s41593-018-0205-2     Document Type: Article
Times cited : (174)

References (70)
  • 2
    • 45749115353 scopus 로고    scopus 로고
    • Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex
    • PID: 18568015
    • Ascoli, G. A. et al. Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex. Nat. Rev. Neurosci. 9, 557–568 (2008)
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 557-568
    • Ascoli, G.A.1
  • 3
    • 84943612722 scopus 로고    scopus 로고
    • Reconstruction and simulation of neocortical microcircuitry
    • PID: 26451489
    • Markram, H. et al. Reconstruction and simulation of neocortical microcircuitry. Cell 163, 456–492 (2015)
    • (2015) Cell , vol.163 , pp. 456-492
    • Markram, H.1
  • 4
    • 84961327715 scopus 로고    scopus 로고
    • Adult mouse cortical cell taxonomy revealed by single cell transcriptomics
    • PID: 26727548
    • Tasic, B. et al. Adult mouse cortical cell taxonomy revealed by single cell transcriptomics. Nat. Neurosci. 19, 335–346 (2016)
    • (2016) Nat. Neurosci. , vol.19 , pp. 335-346
    • Tasic, B.1
  • 5
    • 84924565530 scopus 로고    scopus 로고
    • Brain structure. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
    • PID: 25700174
    • Zeisel, A. et al. Brain structure. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq. Science 347, 1138–1142 (2015)
    • (2015) Science , vol.347 , pp. 1138-1142
    • Zeisel, A.1
  • 6
    • 84929684999 scopus 로고    scopus 로고
    • Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets
    • PID: 26000488
    • Macosko, E. Z. et al. Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets. Cell 161, 1202–1214 (2015)
    • (2015) Cell , vol.161 , pp. 1202-1214
    • Macosko, E.Z.1
  • 7
    • 84948449322 scopus 로고    scopus 로고
    • Principles of connectivity among morphologically defined cell types in adult neocortex
    • PID: 26612957
    • Jiang, X. et al. Principles of connectivity among morphologically defined cell types in adult neocortex. Science 350, aac9462 (2015)
    • (2015) Science , vol.350 , pp. aac9462
    • Jiang, X.1
  • 8
    • 84994753130 scopus 로고    scopus 로고
    • Unique membrane properties and enhanced signal processing in human neocortical neurons
    • PID: 27710767
    • Eyal, G. et al. Unique membrane properties and enhanced signal processing in human neocortical neurons. eLife 5, e16553 (2016)
    • (2016) eLife , vol.5
    • Eyal, G.1
  • 9
    • 84924545990 scopus 로고    scopus 로고
    • A subtype of inhibitory interneuron with intrinsic persistent activity in human and monkey neocortex
    • Wang, B. et al. A subtype of inhibitory interneuron with intrinsic persistent activity in human and monkey neocortex. Cell Rep. 10, 1450–1458 (2015)
    • (2015) Cell Rep. , vol.10 , pp. 1450-1458
    • Wang, B.1
  • 10
    • 54649083758 scopus 로고    scopus 로고
    • Complex events initiated by individual spikes in the human cerebral cortex
    • PID: 18767905
    • Molnár, G. et al. Complex events initiated by individual spikes in the human cerebral cortex. PLoS Biol. 6, e222 (2008)
    • (2008) PLoS Biol. , vol.6
    • Molnár, G.1
  • 11
    • 84983591473 scopus 로고    scopus 로고
    • Human pyramidal to interneuron synapses are mediated by multi-vesicular release and multiple docked vesicles
    • PID: 27536876
    • Molnár, G. et al. Human pyramidal to interneuron synapses are mediated by multi-vesicular release and multiple docked vesicles. eLife 5, e18167 (2016)
    • (2016) eLife , vol.5
    • Molnár, G.1
  • 12
    • 81555199653 scopus 로고    scopus 로고
    • Human synapses show a wide temporal window for spike-timing-dependent plasticity
    • PID: 21423498
    • Testa-Silva, G. et al. Human synapses show a wide temporal window for spike-timing-dependent plasticity. Front. Synaptic Neurosci. 2, 12 (2010)
    • (2010) Front. Synaptic Neurosci. , vol.2 , pp. 12
    • Testa-Silva, G.1
  • 13
    • 84886871639 scopus 로고    scopus 로고
    • Mechanisms underlying the rules for associative plasticity at adult human neocortical synapses
    • PID: 24155324
    • Verhoog, M. B. et al. Mechanisms underlying the rules for associative plasticity at adult human neocortical synapses. J. Neurosci. 33, 17197–17208 (2013)
    • (2013) J. Neurosci. , vol.33 , pp. 17197-17208
    • Verhoog, M.B.1
  • 14
    • 85007333975 scopus 로고    scopus 로고
    • Plasticity in single axon glutamatergic connection interneurons regulates complex events in the human neocortex to GABAergic
    • PID: 27828957
    • Szegedi, V. et al. Plasticity in single axon glutamatergic connection interneurons regulates complex events in the human neocortex to GABAergic. PLoS Biol. 14, e2000237 (2016)
    • (2016) PLoS Biol. , vol.14
    • Szegedi, V.1
  • 15
    • 0034666776 scopus 로고    scopus 로고
    • Pyramidal cells of the frontal lobe: all the more spinous to think with
    • PID: 10974092
    • Elston, G. N. Pyramidal cells of the frontal lobe: all the more spinous to think with. J. Neurosci. 20, RC95 (2000)
    • (2000) J. Neurosci. , vol.20 , pp. RC95
    • Elston, G.N.1
  • 16
    • 84904550486 scopus 로고    scopus 로고
    • Random positions of dendritic spines in human cerebral cortex
    • PID: 25057209
    • Morales, J. et al. Random positions of dendritic spines in human cerebral cortex. J. Neurosci. 34, 10078–10084 (2014)
    • (2014) J. Neurosci. , vol.34 , pp. 10078-10084
    • Morales, J.1
  • 17
    • 84959449833 scopus 로고    scopus 로고
    • Dendritic and axonal architecture of individual pyramidal neurons across layers of adult human neocortex
    • PID: 26318661
    • Mohan, H. et al. Dendritic and axonal architecture of individual pyramidal neurons across layers of adult human neocortex. Cereb. Cortex 25, 4839–4853 (2015)
    • (2015) Cereb. Cortex , vol.25 , pp. 4839-4853
    • Mohan, H.1
  • 18
    • 84889686392 scopus 로고    scopus 로고
    • RNA-sequencing from single nuclei
    • PID: 24248345
    • Grindberg, R. V. et al. RNA-sequencing from single nuclei. Proc. Natl. Acad. Sci. USA 110, 19802–19807 (2013)
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 19802-19807
    • Grindberg, R.V.1
  • 19
    • 84973299445 scopus 로고    scopus 로고
    • Nuclear RNA-seq of single neurons reveals molecular signatures of activation
    • PID: 27090946
    • Lacar, B. et al. Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nat. Commun. 7, 11022 (2016)
    • (2016) Nat. Commun. , vol.7
    • Lacar, B.1
  • 20
    • 84891677425 scopus 로고    scopus 로고
    • Full-length RNA-seq from single cells using Smart-seq2
    • PID: 24385147
    • Picelli, S. et al. Full-length RNA-seq from single cells using Smart-seq2. Nat. Protoc. 9, 171–181 (2014)
    • (2014) Nat. Protoc. , vol.9 , pp. 171-181
    • Picelli, S.1
  • 21
    • 0030794494 scopus 로고    scopus 로고
    • GABAergic cell subtypes and their synaptic connections in rat frontal cortex
    • PID: 9276173
    • Kawaguchi, Y. & Kubota, Y. GABAergic cell subtypes and their synaptic connections in rat frontal cortex. Cereb. Cortex 7, 476–486 (1997)
    • (1997) Cereb. Cortex , vol.7 , pp. 476-486
    • Kawaguchi, Y.1    Kubota, Y.2
  • 22
    • 84976276942 scopus 로고    scopus 로고
    • Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain
    • PID: 27339989
    • Lake, B. B. et al. Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain. Science 352, 1586–1590 (2016)
    • (2016) Science , vol.352 , pp. 1586-1590
    • Lake, B.B.1
  • 23
    • 61349104867 scopus 로고    scopus 로고
    • Output of neurogliaform cells to various neuron types in the human and rat cerebral cortex
    • PID: 18946546
    • Oláh, S. et al. Output of neurogliaform cells to various neuron types in the human and rat cerebral cortex. Front. Neural Circuits 1, 4 (2007)
    • (2007) Front. Neural Circuits , vol.1 , pp. 4
    • Oláh, S.1
  • 24
    • 0025329180 scopus 로고
    • Synapses, axonal and dendritic patterns of GABA-immunoreactive neurons in human cerebral cortex
    • PID: 2194628
    • Kisvárday, Z. F. et al. Synapses, axonal and dendritic patterns of GABA-immunoreactive neurons in human cerebral cortex. Brain 113, 793–812 (1990)
    • (1990) Brain , vol.113 , pp. 793-812
    • Kisvárday, Z.F.1
  • 25
    • 70350686715 scopus 로고    scopus 로고
    • Regulation of cortical microcircuits by unitary GABA-mediated volume transmission
    • PID: 19865171
    • Oláh, S. et al. Regulation of cortical microcircuits by unitary GABA-mediated volume transmission. Nature 461, 1278–1281 (2009)
    • (2009) Nature , vol.461 , pp. 1278-1281
    • Oláh, S.1
  • 26
    • 84954240560 scopus 로고    scopus 로고
    • Molecular and electrophysiological characterization of GABAergic interneurons expressing the transcription factor COUP-TFII in the adult human temporal cortex
    • PID: 25787832
    • Varga, C., Tamas, G., Barzo, P., Olah, S. & Somogyi, P. Molecular and electrophysiological characterization of GABAergic interneurons expressing the transcription factor COUP-TFII in the adult human temporal cortex. Cereb. Cortex 25, 4430–4449 (2015)
    • (2015) Cereb. Cortex , vol.25 , pp. 4430-4449
    • Varga, C.1    Tamas, G.2    Barzo, P.3    Olah, S.4    Somogyi, P.5
  • 27
    • 77954633795 scopus 로고    scopus 로고
    • Differences in subthreshold resonance of hippocampal pyramidal cells and interneurons: the role of h-current and passive membrane characteristics
    • Zemankovics, R., Káli, S., Paulsen, O., Freund, T. F. & Hájos, N. Differences in subthreshold resonance of hippocampal pyramidal cells and interneurons: the role of h-current and passive membrane characteristics. J. Physiol. (Lond.) 588, 2109–2132 (2010)
    • (2010) J. Physiol. (Lond.) , vol.588 , pp. 2109-2132
    • Zemankovics, R.1    Káli, S.2    Paulsen, O.3    Freund, T.F.4    Hájos, N.5
  • 28
    • 84862677848 scopus 로고    scopus 로고
    • Multiple functions of endocannabinoid signaling in the brain
    • PID: 22524785
    • Katona, I. & Freund, T. F. Multiple functions of endocannabinoid signaling in the brain. Annu. Rev. Neurosci. 35, 529–558 (2012)
    • (2012) Annu. Rev. Neurosci. , vol.35 , pp. 529-558
    • Katona, I.1    Freund, T.F.2
  • 29
    • 84926208475 scopus 로고    scopus 로고
    • Combined two-photon imaging, electrophysiological, and anatomical investigation of the human neocortex in vitro
    • PID: 26157969
    • Kerekes, B. P. et al. Combined two-photon imaging, electrophysiological, and anatomical investigation of the human neocortex in vitro. Neurophotonics 1, 011013 (2014)
    • (2014) Neurophotonics , vol.1 , pp. 011013
    • Kerekes, B.P.1
  • 30
    • 0030337503 scopus 로고    scopus 로고
    • Interneurons of the hippocampus
    • PID: 8915675
    • Freund, T. F. & Buzsáki, G. Interneurons of the hippocampus. Hippocampus 6, 347–470 (1996)
    • (1996) Hippocampus , vol.6 , pp. 347-470
    • Freund, T.F.1    Buzsáki, G.2
  • 31
    • 84866518216 scopus 로고    scopus 로고
    • An anatomically comprehensive atlas of the adult human brain transcriptome
    • PID: 22996553
    • Hawrylycz, M. J. et al. An anatomically comprehensive atlas of the adult human brain transcriptome. Nature 489, 391–399 (2012)
    • (2012) Nature , vol.489 , pp. 391-399
    • Hawrylycz, M.J.1
  • 32
    • 33846252240 scopus 로고    scopus 로고
    • Genome-wide atlas of gene expression in the adult mouse brain
    • PID: 17151600
    • Lein, E. S. et al. Genome-wide atlas of gene expression in the adult mouse brain. Nature 445, 168–176 (2007)
    • (2007) Nature , vol.445 , pp. 168-176
    • Lein, E.S.1
  • 34
    • 0031474097 scopus 로고    scopus 로고
    • Types of neurons, synaptic connections and chemical characteristics of cells immunoreactive for calbindin-D28K, parvalbumin and calretinin in the neocortex
    • PID: 9498163
    • DeFelipe, J. Types of neurons, synaptic connections and chemical characteristics of cells immunoreactive for calbindin-D28K, parvalbumin and calretinin in the neocortex. J. Chem. Neuroanat. 14, 1–19 (1997)
    • (1997) J. Chem. Neuroanat. , vol.14 , pp. 1-19
    • DeFelipe, J.1
  • 35
    • 84951511193 scopus 로고
    • Eine neue Art Spezialzellen des Lobus cinguli and Lobus insulae
    • von Economo, C. Eine neue Art Spezialzellen des Lobus cinguli and Lobus insulae. Zschr. ges Neurol. Psychiatry 100, 706–712 (1926)
    • (1926) Zschr. ges Neurol. Psychiatry , vol.100 , pp. 706-712
    • von Economo, C.1
  • 36
    • 0029007601 scopus 로고
    • Spindle neurons of the human anterior cingulate cortex
    • PID: 7636011
    • Nimchinsky, E. A., Vogt, B. A., Morrison, J. H. & Hof, P. R. Spindle neurons of the human anterior cingulate cortex. J. Comp. Neurol. 355, 27–37 (1995)
    • (1995) J. Comp. Neurol. , vol.355 , pp. 27-37
    • Nimchinsky, E.A.1    Vogt, B.A.2    Morrison, J.H.3    Hof, P.R.4
  • 37
    • 84966269185 scopus 로고    scopus 로고
    • Subpial Fan Cell” - a class of calretinin neuron in layer 1 of adult monkey prefrontal cortex
    • PID: 27147978
    • Gabbott, P. L. A. Subpial Fan Cell” - a class of calretinin neuron in layer 1 of adult monkey prefrontal cortex. Front. Neuroanat. 10, 28 (2016)
    • (2016) Front. Neuroanat. , vol.10 , pp. 28
    • Gabbott, P.L.A.1
  • 38
    • 84900303453 scopus 로고    scopus 로고
    • Transcriptional landscape of the prenatal human brain
    • PID: 24695229
    • Miller, J. A. et al. Transcriptional landscape of the prenatal human brain. Nature 508, 199–206 (2014)
    • (2014) Nature , vol.508 , pp. 199-206
    • Miller, J.A.1
  • 39
    • 0017741622 scopus 로고
    • A specific ‘axo-axonal’ interneuron in the visual cortex of the rat
    • PID: 922488
    • Somogyi, P. A specific ‘axo-axonal’ interneuron in the visual cortex of the rat. Brain Res. 136, 345–350 (1977)
    • (1977) Brain Res. , vol.136 , pp. 345-350
    • Somogyi, P.1
  • 40
    • 0030988211 scopus 로고    scopus 로고
    • Fast IPSPs elicited via multiple synaptic release sites by different types of GABAergic neuron in the cat visual cortex
    • Tamás, G., Buhl, E. H. & Somogyi, P. Fast IPSPs elicited via multiple synaptic release sites by different types of GABAergic neuron in the cat visual cortex. J. Physiol. (Lond.) 500, 715–738 (1997)
    • (1997) J. Physiol. (Lond.) , vol.500 , pp. 715-738
    • Tamás, G.1    Buhl, E.H.2    Somogyi, P.3
  • 41
    • 0022380780 scopus 로고
    • Synaptic connections of intracellularly filled clutch cells: a type of small basket cell in the visual cortex of the cat
    • PID: 4067011
    • Kisvárday, Z. F., Martin, K. A. C., Whitteridge, D. & Somogyi, P. Synaptic connections of intracellularly filled clutch cells: a type of small basket cell in the visual cortex of the cat. J. Comp. Neurol. 241, 111–137 (1985)
    • (1985) J. Comp. Neurol. , vol.241 , pp. 111-137
    • Kisvárday, Z.F.1    Martin, K.A.C.2    Whitteridge, D.3    Somogyi, P.4
  • 42
    • 84938652000 scopus 로고    scopus 로고
    • Canonical organization of layer 1 neuron-led cortical inhibitory and disinhibitory interneuronal circuits
    • PID: 24554728
    • Lee, A. J. et al. Canonical organization of layer 1 neuron-led cortical inhibitory and disinhibitory interneuronal circuits. Cereb. Cortex 25, 2114–2126 (2015)
    • (2015) Cereb. Cortex , vol.25 , pp. 2114-2126
    • Lee, A.J.1
  • 43
    • 84992129616 scopus 로고    scopus 로고
    • GABAergic interneurons in the neocortex: from cellular properties to circuits
    • PID: 27477017
    • Tremblay, R., Lee, S. & Rudy, B. GABAergic interneurons in the neocortex: from cellular properties to circuits. Neuron 91, 260–292 (2016)
    • (2016) Neuron , vol.91 , pp. 260-292
    • Tremblay, R.1    Lee, S.2    Rudy, B.3
  • 44
    • 84954286177 scopus 로고    scopus 로고
    • Computational implications of biophysical diversity and multiple timescales in neurons and synapses for circuit performance
    • PID: 26774694
    • Gjorgjieva, J., Drion, G. & Marder, E. Computational implications of biophysical diversity and multiple timescales in neurons and synapses for circuit performance. Curr. Opin. Neurobiol. 37, 44–52 (2016)
    • (2016) Curr. Opin. Neurobiol. , vol.37 , pp. 44-52
    • Gjorgjieva, J.1    Drion, G.2    Marder, E.3
  • 45
    • 84857600801 scopus 로고    scopus 로고
    • The cellular basis of GABA(B)-mediated interhemispheric inhibition
    • PID: 22363012
    • Palmer, L. M. et al. The cellular basis of GABA(B)-mediated interhemispheric inhibition. Science 335, 989–993 (2012)
    • (2012) Science , vol.335 , pp. 989-993
    • Palmer, L.M.1
  • 46
    • 46849083268 scopus 로고    scopus 로고
    • Neuronal diversity and temporal dynamics: the unity of hippocampal circuit operations
    • PID: 18599766
    • Klausberger, T. & Somogyi, P. Neuronal diversity and temporal dynamics: the unity of hippocampal circuit operations. Science 321, 53–57 (2008)
    • (2008) Science , vol.321 , pp. 53-57
    • Klausberger, T.1    Somogyi, P.2
  • 47
    • 23644441933 scopus 로고    scopus 로고
    • Disruption of Netrin G1 by a balanced chromosome translocation in a girl with Rett syndrome
    • PID: 15870826
    • Borg, I. et al. Disruption of Netrin G1 by a balanced chromosome translocation in a girl with Rett syndrome. Eur. J. Hum. Genet. 13, 921–927 (2005)
    • (2005) Eur. J. Hum. Genet. , vol.13 , pp. 921-927
    • Borg, I.1
  • 48
    • 18744371004 scopus 로고    scopus 로고
    • Truncating neurotrypsin mutation in autosomal recessive nonsyndromic mental retardation
    • PID: 12459588
    • Molinari, F. et al. Truncating neurotrypsin mutation in autosomal recessive nonsyndromic mental retardation. Science 298, 1779–1781 (2002)
    • (2002) Science , vol.298 , pp. 1779-1781
    • Molinari, F.1
  • 49
    • 84892960440 scopus 로고    scopus 로고
    • Lost in translation: animal models and clinical trials in cancer treatment
    • PID: 24489990
    • Mak, I. W., Evaniew, N. & Ghert, M. Lost in translation: animal models and clinical trials in cancer treatment. Am. J. Transl. Res. 6, 114–118 (2014)
    • (2014) Am. J. Transl. Res. , vol.6 , pp. 114-118
    • Mak, I.W.1    Evaniew, N.2    Ghert, M.3
  • 50
    • 84904869948 scopus 로고    scopus 로고
    • Animal models of Alzheimer disease: historical pitfalls and a path forward
    • PID: 24793844
    • Cavanaugh, S. E., Pippin, J. J. & Barnard, N. D. Animal models of Alzheimer disease: historical pitfalls and a path forward. ALTEX 31, 279–302 (2014)
    • (2014) ALTEX , vol.31 , pp. 279-302
    • Cavanaugh, S.E.1    Pippin, J.J.2    Barnard, N.D.3
  • 51
    • 84959361379 scopus 로고    scopus 로고
    • Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons
    • PID: 26890679
    • Krishnaswami, S. R. et al. Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons. Nat. Protoc. 11, 499–524 (2016)
    • (2016) Nat. Protoc. , vol.11 , pp. 499-524
    • Krishnaswami, S.R.1
  • 52
    • 84905049901 scopus 로고    scopus 로고
    • Trimmomatic: a flexible trimmer for Illumina sequence data
    • PID: 24695404
    • Bolger, A. M., Lohse, M. & Usadel, B. Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics 30, 2114–2120 (2014)
    • (2014) Bioinformatics , vol.30 , pp. 2114-2120
    • Bolger, A.M.1    Lohse, M.2    Usadel, B.3
  • 53
    • 79961123152 scopus 로고    scopus 로고
    • RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
    • PID: 21816040
    • Li, B. & Dewey, C. N. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics 12, 323 (2011)
    • (2011) BMC Bioinformatics , vol.12
    • Li, B.1    Dewey, C.N.2
  • 54
    • 84859885816 scopus 로고    scopus 로고
    • Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
    • PID: 22383036
    • Trapnell, C. et al. Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks. Nat. Protoc. 7, 562–578 (2012)
    • (2012) Nat. Protoc. , vol.7 , pp. 562-578
    • Trapnell, C.1
  • 55
    • 84865074382 scopus 로고    scopus 로고
    • RSeQC: quality control of RNA-seq experiments
    • PID: 22743226
    • Wang, L., Wang, S. & Li, W. RSeQC: quality control of RNA-seq experiments. Bioinformatics 28, 2184–2185 (2012)
    • (2012) Bioinformatics , vol.28 , pp. 2184-2185
    • Wang, L.1    Wang, S.2    Li, W.3
  • 56
    • 84861743958 scopus 로고    scopus 로고
    • RNA-SeQC: RNA-seq metrics for quality control and process optimization
    • PID: 22539670
    • DeLuca, D. S. et al. RNA-SeQC: RNA-seq metrics for quality control and process optimization. Bioinformatics 28, 1530–1532 (2012)
    • (2012) Bioinformatics , vol.28 , pp. 1530-1532
    • DeLuca, D.S.1
  • 57
    • 84928987900 scopus 로고    scopus 로고
    • HTSeq--a Python framework to work with high-throughput sequencing data
    • PID: 25260700
    • Anders, S., Pyl, P. T. & Huber, W. HTSeq--a Python framework to work with high-throughput sequencing data. Bioinformatics 31, 166–169 (2015)
    • (2015) Bioinformatics , vol.31 , pp. 166-169
    • Anders, S.1    Pyl, P.T.2    Huber, W.3
  • 58
    • 85015607256 scopus 로고    scopus 로고
    • Production of a preliminary quality control pipeline for single nuclei RNA-seq and its application in the analysis of cell type diversity of post-mortem human brain neocortex
    • PID: 27897007
    • Aevermann, B. et al. Production of a preliminary quality control pipeline for single nuclei RNA-seq and its application in the analysis of cell type diversity of post-mortem human brain neocortex. Pac. Symp. Biocomput. 22, 564–575 (2017)
    • (2017) Pac. Symp. Biocomput. , vol.22 , pp. 564-575
    • Aevermann, B.1
  • 60
    • 84883368195 scopus 로고    scopus 로고
    • Software for computing and annotating genomic ranges
    • PID: 23950696
    • Lawrence, M. et al. Software for computing and annotating genomic ranges. PLOS Comput. Biol. 9, e1003118 (2013)
    • (2013) PLOS Comput. Biol. , vol.9
    • Lawrence, M.1
  • 61
    • 75249087100 scopus 로고    scopus 로고
    • edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
    • PID: 19910308
    • Robinson, M. D., McCarthy, D. J. & Smyth, G. K. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26, 139–140 (2010)
    • (2010) Bioinformatics , vol.26 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3
  • 62
    • 84959189722 scopus 로고    scopus 로고
    • Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis
    • PID: 26780092
    • Fan, J. et al. Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis. Nat. Methods 13, 241–244 (2016)
    • (2016) Nat. Methods , vol.13 , pp. 241-244
    • Fan, J.1
  • 63
    • 57249084011 scopus 로고    scopus 로고
    • Visualizing high-dimensional data using t-SNE
    • Van Der Maaten, L. J. P. & Hinton, G. E. Visualizing high-dimensional data using t-SNE. J. Mach. Learn. Res. 9, 2579–2605 (2008)
    • (2008) J. Mach. Learn. Res. , vol.9 , pp. 2579-2605
    • Van Der Maaten, L.J.P.1    Hinton, G.E.2
  • 64
    • 85170282443 scopus 로고    scopus 로고
    • A density-based algorithm for discovering clusters in large spatial databases with noise
    • Ester, M., Kriegel, H. P., Sander, J. & Xu, X. A density-based algorithm for discovering clusters in large spatial databases with noise. KDD 2, 226–231 (1996)
    • (1996) KDD , vol.2 , pp. 226-231
    • Ester, M.1    Kriegel, H.P.2    Sander, J.3    Xu, X.4
  • 65
    • 54949118365 scopus 로고    scopus 로고
    • Statistical significance of clustering for high-dimension, low–sample size data
    • Liu, Y., Hayes, D. N., Nobel, A. & Marron, J. S. Statistical significance of clustering for high-dimension, low–sample size data. J. Am. Stat. Assoc. 103, 1281–1293 (2008)
    • (2008) J. Am. Stat. Assoc. , vol.103 , pp. 1281-1293
    • Liu, Y.1    Hayes, D.N.2    Nobel, A.3    Marron, J.S.4
  • 67
    • 84926507971 scopus 로고    scopus 로고
    • limma powers differential expression analyses for RNA-sequencing and microarray studies
    • PID: 25605792
    • Ritchie, M. E. et al. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res. 43, e47 (2015)
    • (2015) Nucleic Acids Res. , vol.43
    • Ritchie, M.E.1
  • 68
    • 84859744583 scopus 로고    scopus 로고
    • Large-scale cellular-resolution gene profiling in human neocortex reveals species-specific molecular signatures
    • PID: 22500809
    • Zeng, H. et al. Large-scale cellular-resolution gene profiling in human neocortex reveals species-specific molecular signatures. Cell 149, 483–496 (2012)
    • (2012) Cell , vol.149 , pp. 483-496
    • Zeng, H.1
  • 70
    • 84879033112 scopus 로고    scopus 로고
    • Digital PCR to determine the number of transcripts from single neurons after patch-clamp recording
    • PID: 23750542
    • Faragó, N. et al. Digital PCR to determine the number of transcripts from single neurons after patch-clamp recording. Biotechniques 54, 327–336 (2013)
    • (2013) Biotechniques , vol.54 , pp. 327-336
    • Faragó, N.1


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