JAGN1 is required for fungal killing in neutrophil extracellular traps: Implications for severe congenital neutropenia

Journal of Leukocyte Biology

Volumn 104, Issue 6, 2018, Pages 1199-1213

  Khandagale, Avinash ^a   Lazzaretto, Beatrice ^a   Carlsson, Göran ^b   Sundin, Mikael ^b   Shafeeq, Sulman ^a   Römling, Ute ^a   Fadeel, Bengt ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

JAGN1; myeloperoxidase; neutrophil extracellular traps; severe congenital neutropenia

Indexed keywords

CALGRANULIN; CELL PROTEIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; JAGUNAL HOMOLOG 1; MYELOPEROXIDASE; PHORBOL 13 ACETATE 12 MYRISTATE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; FILGRASTIM; JAGN1 PROTEIN, HUMAN; MEMBRANE PROTEIN; MESSENGER RNA; MPO PROTEIN, HUMAN; PEROXIDASE;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CFU COUNTING; CONTROLLED STUDY; DEGLYCOSYLATION; DOWN REGULATION; ENZYME ACTIVITY; EXTRACELLULAR TRAP; FEMALE; FUNGUS GROWTH; FUNGUS HYPHAE; GENE EXPRESSION REGULATION; GENE MUTATION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HL-60 CELL LINE; HOMOZYGOSITY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION LEVEL; PROTEIN GLYCOSYLATION; SEVERE CONGENITAL NEUTROPENIA; UPREGULATION; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DEFICIENCY; DRUG EFFECT; ENZYMOLOGY; GENETICS; IMMUNOLOGY; MALE; NEUTROPENIA; NEUTROPHIL; PHYSIOLOGY; PRESCHOOL CHILD; RNA INTERFERENCE;

CANDIDA ALBICANS; CHILD, PRESCHOOL; EXTRACELLULAR TRAPS; FILGRASTIM; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HL-60 CELLS; HUMANS; MALE; MEMBRANE PROTEINS; NEUTROPENIA; NEUTROPHILS; PEROXIDASE; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; TETRADECANOYLPHORBOL ACETATE; TRANSFECTION;

EID: 85052465652     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1002/JLB.4A0118-030RR     Document Type: Article

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