Overview of the NASA 70-day Bed Rest Study

Medicine and Science in Sports and Exercise

Volumn 50, Issue 9, 2018, Pages 1909-1919

  Cromwell, Ronita L ^a   Scott, Jessica M ^b   Downs, Meghan ^c   Yarbough, Patrice O ^d   Zanello, Susana B ^d   Ploutz Snyder, Lori ^e  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c UNIVERSITY OF HOUSTON   (United States)

^d KBRWYLE   (United States)

^e UNIVERSITY OF MICHIGAN   (United States)

Author keywords

ADAPTABILITY; BED REST; DECONDITIONING; EXERCISE; SPACEFLIGHT; TESTOSTERONE

Indexed keywords

TESTOSTERONE;

ADULT; BED REST; CONTROLLED STUDY; EXERCISE; FEMALE; GOVERNMENT; HEAD-DOWN TILT; HUMAN; MALE; RANDOMIZED CONTROLLED TRIAL; RESISTANCE TRAINING; SPACE FLIGHT; TIME FACTOR; UNITED STATES; WEIGHTLESSNESS;

ADULT; BED REST; EXERCISE; FEMALE; HEAD-DOWN TILT; HUMANS; MALE; RESISTANCE TRAINING; SPACE FLIGHT; TESTOSTERONE; TIME FACTORS; UNITED STATES; UNITED STATES NATIONAL AERONAUTICS AND SPACE ADMINISTRATION; WEIGHTLESSNESS SIMULATION;

EID: 85051591145     PISSN: 01959131     EISSN: 15300315     Source Type: Journal    
DOI: 10.1249/MSS.0000000000001617     Document Type: Article

References (19)

1. Bloomberg JJ, Peters BT, Cohen HS, Mulavara AP. Enhancing astronaut performance using sensorimotor adaptability training. Front Sys Neurosci. 2015;9:129.
2. Lang TF, LeBlanc AD, Evans HJ, Lu Y. Adaptation of the proximal femur to skeletal reloading after long-duration spaceflight. J Bone Miner Res. 2006;21(8):1224-30.
3. Platts SH, Merz CN, Barr Y, et al. Effects of sex and gender on adaptation to space: cardiovascular alterations. J Womens Health. 2014;23(11):950-5.
4. Tesch PA, Berg HE, Bring D, Evans HJ, LeBlanc AD. Effects of 17-day spaceflight on knee extensor muscle function and size. Eur J Appl Physiol. 2005;93:463-8.
5. Trappe S, Costill D, Gallagher P, et al. Exercise in space: human skeletal muscle after 6 months aboard the international space station. J Appl Physiol. 2009;106:1159-68.
6. Belav DL, Bock O, Börst H, et al. The 2nd Berlin BedRest Study: protocol and implementation. J Musculoskelet Neuronal Interact. 2010;10(3):207-19.
7. Meck JV, Dreyer SA, Warren LE. Long-duration head-down bed rest: project overview, vital signs, and fluid balance. Aviat Space Environ Med. 2009;80(5 Suppl):A1-8.
8. Pavy-Le Traon A, Heer M, Narici MV, Rittweger J, Vernikos J. From space to Earth: Advances in human physiology from 20 years of bed rest studies (1986-2006). Eur J Appl Physiol. 2007;101:143-94.
9. Saltin B, Blomqvist G, Mitchell JH, Johnson RL Jr, Wildenthal K, Chapman CB. Response to exercise after bed rest and after training. Circulation. 1968;38:VII1-78.
10. Sundblad P, Orlov O (editors). Guidelines for Standardization of Bed Rest Studies in the Spaceflight Context. International Academy of Astronautics; ISBN/EAN IAA: 9782917761342, 2015. Available from: http://www. nasa. gov/hrp/important-documents.
11. Sundblad P, Orlov O, Angerer O, Larina I, Cromwell R. Standardization of bed rest studies in the spaceflight context. J Appl Physiol. 2016;121:348-9.
12. Crucian BE, Stowe RP, Mehta SK, et al. Immune status, latent viral reactivation, and stress during long-duration head-down bed rest. Aviat Space Environ Med. 2009;80(5 Suppl):A37-44.
13. Platts SH, Martin DS, Stenger MB, et al. Cardiovascular adaptations to long-duration head-down bed rest. Aviat Space Environ Med. 2009;80(5 Suppl):A29-36.
14. Reschke MF, Bloomberg JJ, Paloski WH, Mulavara AP, Feiveson AH, Harm DL. Postural reflexes, balance control, and functional mobility with long-duration head-down bed rest. Aviat Space Environ Med. 2009;80(5 Suppl):A45-54.
15. Zwart SR, Mathews Oliver SA, Fesperman JV, et al. Nutritional status assessment before, during, and after long-duration headdown bed rest. Aviat Space Environ Med. 2009;80(5 Suppl): A15-22.
16. Ploutz-Snyder LL, Downs M, Ryder J, et al. Integrated resistance and aerobic exercise protects fitness during bed rest. Med Sci Sports Exerc. 2014;46:358-68.
17. Moore AD, Downs ME, Lee SM, Feiveson AH, Knudsen P, Ploutz-Snyder L. Peak exercise oxygen uptake during and following long-duration spaceflight. J Appl Physiol. 2014;117: 231-8.
18. English KL, Lee SM, Loehr JA, Ploutz-Snyder RJ, Ploutz-Snyder LL. Isokinetic strength changes following long-duration spaceflight on the ISS. Aerospace Med Hum Perf; 86(12 Suppl): A68-77.
19. Innis AM, Rice BL, Smith SM. Dietary support of long-duration head-down bed rest. Aviat Space Environ Med. 2009;80(5 Suppl): A9-14.