Altered oral microbiota in chronic hepatitis B patients with different tongue coatings

World Journal of Gastroenterology

Volumn 24, Issue 30, 2018, Pages 3448-3461

  Zhao, Yu ^a   Mao, Yu Feng ^a   Tang, Yi Shuang ^a   Ni, Ming Zhu ^a   Liu, Qiao Hong ^a   Wang, Yan ^a   Feng, Qin ^a   Peng, Jing Hua ^a   Hu, Yi Yang ^a  

^a SHUGUANG HOSPITAL AFFILIATED TO SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

16S rRNA gene sequencing; Chronic hepatitis B; Metabolomics; Microbiota; Tongue diagnosis

Indexed keywords

S ADENOSYLMETHIONINE; VIRUS DNA; RNA 16S;

ADULT; ARTICLE; BACTEROIDETES; CHRONIC HEPATITIS B; CONTROLLED STUDY; FAMILY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; METABOLITE; METAGENOMICS; MOUTH FLORA; NEISSERIACEAE; NONHUMAN; TONGUE DISEASE; WHITE TONGUE COATING; YELLOW TONGUE COATING; BACTERIUM; CASE CONTROL STUDY; CHINESE MEDICINE; GENETICS; HEPATITIS B VIRUS; INTESTINE FLORA; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; MIDDLE AGED; NORMAL HUMAN; PHYSIOLOGY; PROCEDURES; TONGUE;

ADULT; BACTERIA; CASE-CONTROL STUDIES; DNA, VIRAL; FEMALE; GASTROINTESTINAL MICROBIOME; HEALTHY VOLUNTEERS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; MALE; MEDICINE, CHINESE TRADITIONAL; METAGENOMICS; MIDDLE AGED; RNA, RIBOSOMAL, 16S; TONGUE;

EID: 85051443632     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v24.i30.3448     Document Type: Article

References (38)

1. Ye J, Cai X, Cao P. Problems and prospects of current studies on the microecology of tongue coating. Chin Med 2014; 9: 9 [PMID: 24597827 DOI: 10.1186/1749-8546-9-9]
2. Lira-Junior R, Boström EA. Oral-gut connection: one step closer to an integrated view of the gastrointestinal tract?. Mucosal Immunol 2018; 11: 316-318 [PMID: 29297500 DOI: 10.1038/mi.2017.116]
3. Jiang B, Liang X, Chen Y, Ma T, Liu L, Li J, Jiang R, Chen T, Zhang X, Li S. Integrating next-generation sequencing and traditional tongue diagnosis to determine tongue coating microbiome. Sci Rep 2012; 2: 936 [PMID: 23226834 DOI: 10.1038/srep00936]
4. Sun ZM, Zhao J, Qian P, Wang YQ, Zhang WF, Guo CR, Pang XY, Wang SC, Li FF, Li Q. Metabolic markers and microecological characteristics of tongue coating in patients with chronic gastritis. BMC Complement Altern Med 2013; 13: 227 [PMID: 24041039 DOI: 10.1186/1472-6882-13-227]
5. Wang FS, Fan JG, Zhang Z, Gao B, Wang HY. The global burden of liver disease: the major impact of China. Hepatology 2014; 60: 2099-2108 [PMID: 25164003 DOI: 10.1002/hep.27406]
6. Chassaing B, Etienne-Mesmin L, Gewirtz AT. Microbiota-liver axis in hepatic disease. Hepatology 2014; 59: 328-339 [PMID: 23703735 DOI: 10.1002/hep.26494]
7. Bajaj JS, Betrapally NS, Hylemon PB, Heuman DM, Daita K, White MB, Unser A, Thacker LR, Sanyal AJ, Kang DJ, Sikaroodi M, Gillevet PM. Salivary microbiota reflects changes in gut microbiota in cirrhosis with hepatic encephalopathy. Hepatology 2015; 62: 1260-1271 [PMID: 25820757 DOI: 10.1002/hep.27819]
8. Tsai TY, Livneh H, Hung TH, Lin IH, Lu MC, Yeh CC. Associations between prescribed Chinese herbal medicine and risk of hepatocellular carcinoma in patients with chronic hepatitis B: a nationwide population-based cohort study. BMJ Open 2017; 7: e014571 [PMID: 28122837 DOI: 10.1136/bmjopen-2016-014571]
9. Kang H, Zhao Y, Li C, Chen Y, Tang K, Yang L, Ma C, Peng J, Zhu R, Liu Q, Hu Y, Cao Z. Integrating clinical indexes into four-diagnostic information contributes to the Traditional Chinese Medicine (TCM) syndrome diagnosis of chronic hepatitis B. Sci Rep 2015; 5: 9395 [PMID: 25797918 DOI: 10.1038/srep09395]
10. Zhao Y, Kang H, Peng JH, Xu L, Cao ZW, Hu YY. Key symptoms selection for two major syndromes diagnosis of Chinese medicine in chronic hepatitis B. Chin J Integr Med 2017; 23: 253-260 [PMID: 27225292 DOI: 10.1007/s11655-016-2253-3]
11. Amato KR, Yeoman CJ, Kent A, Righini N, Carbonero F, Estrada A, Gaskins HR, Stumpf RM, Yildirim S, Torralba M, Gillis M, Wilson BA, Nelson KE, White BA, Leigh SR. Habitat degradation impacts black howler monkey (Alouatta pigra) gastrointestinal microbiomes. ISME J 2013; 7: 1344-1353 [PMID: 23486247 DOI: 10.1038/ ismej.2013.16]
12. Segata N, Izard J, Waldron L, Gevers D, Miropolsky L, Garrett WS, Huttenhower C. Metagenomic biomarker discovery and explanation. Genome Biol 2011; 12: R60 [PMID: 21702898 DOI: 10.1186/gb-2011-12-6-r60]
13. Langille MG, Zaneveld J, Caporaso JG, McDonald D, Knights D, Reyes JA, Clemente JC, Burkepile DE, Vega Thurber RL, Knight R, Beiko RG, Huttenhower C. Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences. Nat Biotechnol 2013; 31: 814-821 [PMID: 23975157 DOI: 10.1038/ nbt.2676]
14. Xia J, Sinelnikov IV, Han B, Wishart DS. MetaboAnalyst 3.0 - making metabolomics more meaningful. Nucleic Acids Res 2015; 43: W251-W257 [PMID: 25897128 DOI: 10.1093/nar/gkv380]
15. Koren O, Spor A, Felin J, Fåk F, Stombaugh J, Tremaroli V, Behre CJ, Knight R, Fagerberg B, Ley RE, Bäckhed F. Human oral, gut, and plaque microbiota in patients with atherosclerosis. Proc Natl Acad Sci U S A 2011; 108 Suppl 1: 4592-4598 [PMID: 20937873 DOI: 10.1073/pnas.1011383107]
16. Zhang X, Zhang D, Jia H, Feng Q, Wang D, Liang D, Wu X, Li J, Tang L, Li Y, Lan Z, Chen B, Li Y, Zhong H, Xie H, Jie Z, Chen W, Tang S, Xu X, Wang X, Cai X, Liu S, Xia Y, Li J, Qiao X, Al-Aama JY, Chen H, Wang L, Wu QJ, Zhang F, Zheng W, Li Y, Zhang M, Luo G, Xue W, Xiao L, Li J, Chen W, Xu X, Yin Y, Yang H, Wang J, Kristiansen K, Liu L, Li T, Huang Q, Li Y, Wang J. The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment. Nat Med 2015; 21: 895-905 [PMID: 26214836 DOI: 10.1038/nm.3914]
17. Xiao E, Mattos M, Vieira GHA, Chen S, Corrêa JD, Wu Y, Albiero ML, Bittinger K, Graves DT. Diabetes Enhances IL-17 Expression and Alters the Oral Microbiome to Increase Its Pathogenicity. Cell Host Microbe 2017; 22: 120-128.e4 [PMID: 28704648 DOI: 10.1016/j.chom.2017.06.014]
18. Qin N, Yang F, Li A, Prifti E, Chen Y, Shao L, Guo J, Le Chatelier E, Yao J, Wu L, Zhou J, Ni S, Liu L, Pons N, Batto JM, Kennedy SP, Leonard P, Yuan C, Ding W, Chen Y, Hu X, Zheng B, Qian G, Xu W, Ehrlich SD, Zheng S, Li L. Alterations of the human gut microbiome in liver cirrhosis. Nature 2014; 513: 59-64 [PMID: 25079328 DOI: 10.1038/nature13568]
19. Bashan A, Gibson TE, Friedman J, Carey VJ, Weiss ST, Hohmann EL, Liu YY. Universality of human microbial dynamics. Nature 2016; 534: 259-262 [PMID: 27279224 DOI: 10.1038/nature18301]
20. Atarashi K, Suda W, Luo C, Kawaguchi T, Motoo I, Narushima S, Kiguchi Y, Yasuma K, Watanabe E, Tanoue T, Thaiss CA, Sato M, Toyooka K, Said HS, Yamagami H, Rice SA, Gevers D, Johnson RC, Segre JA, Chen K, Kolls JK, Elinav E, Morita H, Xavier RJ, Hattori M, Honda K. Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation. Science 2017; 358: 359-365 [PMID: 29051379 DOI: 10.1126/science.aan4526]
21. Ding T, Schloss PD. Dynamics and associations of microbial community types across the human body. Nature 2014; 509: 357-360 [PMID: 24739969 DOI: 10.1038/nature13178]
22. Han S, Yang X, Qi Q, Pan Y, Chen Y, Shen J, Liao H, Ji Z. Potential screening and early diagnosis method for cancer: Tongue diagnosis. Int J Oncol 2016; 48: 2257-2264 [PMID: 27035407 DOI: 10.3892/ ijo.2016.3466]
23. RiYang L, HangYing Y, JunYan Q, YaYu L, YuHui W, YaZhen Y, JiaZhen Y, Jin Y, Jun N, DongRong Y. Association between tongue coating thickness and clinical characteristics among idiopathic membranous nephropathy patients. J Ethnopharmacol 2015; 171: 125-130 [PMID: 25997785 DOI: 10.1016/j.jep.2015.05.008]
24. Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature 2012; 486: 207-214 [PMID: 22699609 DOI: 10.1038/nature11234]
25. Lee TC, Lo LC, Wu FC. Traditional Chinese Medicine for Metabolic Syndrome via TCM Pattern Differentiation: Tongue Diagnosis for Predictor. Evid Based Complement Alternat Med 2016; 2016: 1971295 [PMID: 27313640 DOI: 10.1155/2016/1971295]
26. Tilg H, Cani PD, Mayer EA. Gut microbiome and liver diseases. Gut 2016; 65: 2035-2044 [PMID: 27802157 DOI: 10.1136/ gutjnl-2016-312729]
27. Wang J, Wang Y, Zhang X, Liu J, Zhang Q, Zhao Y, Peng J, Feng Q, Dai J, Sun S, Zhao Y, Zhao L, Zhang Y, Hu Y, Zhang M. Gut Microbial Dysbiosis Is Associated with Altered Hepatic Functions and Serum Metabolites in Chronic Hepatitis B Patients. Front Microbiol 2017; 8: 2222 [PMID: 29180991 DOI: 10.3389/ fmicb.2017.02222]
28. Ren YD, Ye ZS, Yang LZ, Jin LX, Wei WJ, Deng YY, Chen XX, Xiao CX, Yu XF, Xu HZ, Xu LZ, Tang YN, Zhou F, Wang XL, Chen MY, Chen LG, Hong MZ, Ren JL, Pan JS. Fecal microbiota transplantation induces hepatitis B virus e-antigen (HBeAg) clearance in patients with positive HBeAg after long-term antiviral therapy. Hepatology 2017; 65: 1765-1768 [PMID: 28027582 DOI: 10.1002/hep.29008]
29. Ling Z, Liu X, Cheng Y, Jiang X, Jiang H, Wang Y, Li L. Decreased Diversity of the Oral Microbiota of Patients with Hepatitis B Virus-Induced Chronic Liver Disease: A Pilot Project. Sci Rep 2015; 5: 17098 [PMID: 26606973 DOI: 10.1038/srep17098]
30. Ren W, Xun Z, Wang Z, Zhang Q, Liu X, Zheng H, Zhang Q, Zhang Y, Zhang L, Wu C, Zheng S, Qin N, Ehrlich SD, Li Y, He X, Xu T, Chen T, Chen F. Tongue Coating and the Salivary Microbial Communities Vary in Children with Halitosis. Sci Rep 2016; 6: 24481 [PMID: 27080513 DOI: 10.1038/srep24481]
31. Aas JA, Paster BJ, Stokes LN, Olsen I, Dewhirst FE. Defining the normal bacterial flora of the oral cavity. J Clin Microbiol 2005; 43: 5721-5732 [PMID: 16272510 DOI: 10.1128/JCM.43.11.5721-5732. 2005]
32. Sun YG, Sun YL. Progress of the study on the relationship between TCM Syndromes of chronic hepatitis B and objective indicators. Zhongyiyao Daobao 2011; 17: 76-78 [DOI: 10.13862/j.cnki. cn43-1446/r.2011.12.027]
33. Lu SC, Mato JM. S-adenosylmethionine in liver health, injury, and cancer. Physiol Rev 2012; 92: 1515-1542 [PMID: 23073625 DOI: 10.1152/physrev.00047.2011]
34. Li R, Ma T, Gu J, Liang X, Li S. Imbalanced network biomarkers for traditional Chinese medicine Syndrome in gastritis patients. Sci Rep 2013; 3: 1543 [PMID: 23529020 DOI: 10.1038/srep01543]
35. Lu YY, Zhao Y, Song YN, Dong S, Wei B, Chen QL, Hu YY, Su SB. Serum cytokine profiling analysis for zheng differentiation in chronic hepatitis B. Chin Med 2015; 10: 24 [PMID: 26312063 DOI: 10.1186/s13020-015-0055-8]
36. Chen Y, Yang F, Lu H, Wang B, Chen Y, Lei D, Wang Y, Zhu B, Li L. Characterization of fecal microbial communities in patients with liver cirrhosis. Hepatology 2011; 54: 562-572 [PMID: 21574172 DOI: 10.1002/hep.24423]
37. Lv LX, Fang DQ, Shi D, Chen DY, Yan R, Zhu YX, Chen YF, Shao L, Guo FF, Wu WR, Li A, Shi HY, Jiang XW, Jiang HY, Xiao YH, Zheng SS, Li LJ. Alterations and correlations of the gut microbiome, metabolism and immunity in patients with primary biliary cirrhosis. Environ Microbiol 2016; 18: 2272-2286 [PMID: 27243236 DOI: 10.1111/1462-2920.13401]
38. Guo Z, Wang WY, Dai JY, Fan ZQ, Cao HJ, Sun SJ, Zhang YY, Xu LM, Hu YY, Su SB. Investigation on Urinary Metabolomic in Syndrome Types of Cirrhosis Caused by Hepatitis B. shijie kexue jishu-zhongyiyao xiandaihua 2012; 14: 1282-1287