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Volumn 113, Issue 11, 2018, Pages 2099-2106

Carbonyl emissions from a novel heated tobacco product (IQOS): comparison with an e-cigarette and a tobacco cigarette

Author keywords

Carbonyls; electronic cigarettes; harm reduction; heated tobacco products; nicotine; smoking

Indexed keywords

2-BUTENAL; ACETALDEHYDE; ACROLEIN; ALDEHYDE; FORMALDEHYDE; PROPIONALDEHYDE;

EID: 85050616717     PISSN: 09652140     EISSN: 13600443     Source Type: Journal    
DOI: 10.1111/add.14365     Document Type: Article
Times cited : (102)

References (39)
  • 1
    • 0027193412 scopus 로고
    • Glycerol particle cigarettes: a less harmful option for chronic smokers
    • Sutherland G., Russell M. A., Stapleton J. A., Feyerabend C. Glycerol particle cigarettes: a less harmful option for chronic smokers. Thorax 1993; 48: 385–387
    • (1993) Thorax , vol.48 , pp. 385-387
    • Sutherland, G.1    Russell, M.A.2    Stapleton, J.A.3    Feyerabend, C.4
  • 3
    • 85037607274 scopus 로고    scopus 로고
    • Philip Morris Products S.A. Modified Risk Tobacco Product (MRTP) Applications., (accessed 18 November 2017) (Archived at, on 3 July 2018)., http://www.webcitation.org/70ciyR1RH
    • U.S Department of Health and Human Services, US Food and Drug Administration. Philip Morris Products S.A. Modified Risk Tobacco Product (MRTP) Applications. 2017. Available at: https://www.fda.gov/TobaccoProducts/Labeling/MarketingandAdvertising/ucm546281.htm (accessed 18 November 2017) (Archived at http://www.webcitation.org/70ciyR1RH on 3 July 2018)
    • (2017) US Food and Drug Administration
  • 4
    • 0345005991 scopus 로고
    • Temperature distribution inside a burning cigarette
    • Baker R. Temperature distribution inside a burning cigarette. Nature 1974; 247: 405–406
    • (1974) Nature , vol.247 , pp. 405-406
    • Baker, R.1
  • 6
    • 85010703428 scopus 로고    scopus 로고
    • Aerosol from tobacco heating system 2.2 has reduced impact on mouse heart gene expression compared with cigarette smoke
    • Szostak J., Boué S., Talikka M., Guedj E., Martin F., Phillips B. et al. Aerosol from tobacco heating system 2.2 has reduced impact on mouse heart gene expression compared with cigarette smoke. Food Chem Toxicol 2017; 101: 157–167
    • (2017) Food Chem Toxicol , vol.101 , pp. 157-167
    • Szostak, J.1    Boué, S.2    Talikka, M.3    Guedj, E.4    Martin, F.5    Phillips, B.6
  • 7
    • 85033492673 scopus 로고    scopus 로고
    • Assessment of novel tobacco heating product THP1.0. Part 3: comprehensive chemical characterisation of harmful and potentially harmful aerosol emissions
    • Forster M., Fiebelkorn S., Yurteri C., Mariner D., Liu C., Wright C. et al. Assessment of novel tobacco heating product THP1.0. Part 3: comprehensive chemical characterisation of harmful and potentially harmful aerosol emissions. Regul Toxicol Pharmacol 2018; 93: 14–33
    • (2018) Regul Toxicol Pharmacol , vol.93 , pp. 14-33
    • Forster, M.1    Fiebelkorn, S.2    Yurteri, C.3    Mariner, D.4    Liu, C.5    Wright, C.6
  • 8
    • 85006942693 scopus 로고    scopus 로고
    • Evaluation of the tobacco heating system 2.2. Part 2: chemical composition, genotoxicity, cytotoxicity, and physical properties of the aerosol
    • Schaller J. P., Keller D., Poget L., Pratte P., Kaelin E., McHugh D. et al. Evaluation of the tobacco heating system 2.2. Part 2: chemical composition, genotoxicity, cytotoxicity, and physical properties of the aerosol. Regul Toxicol Pharmacol 2016; 81: S27–S47
    • (2016) Regul Toxicol Pharmacol , vol.81 , pp. S27-S47
    • Schaller, J.P.1    Keller, D.2    Poget, L.3    Pratte, P.4    Kaelin, E.5    McHugh, D.6
  • 9
    • 85054305240 scopus 로고    scopus 로고
    • Nicotine delivery to the aerosol of a heat-not-burn tobacco product: comparison with a tobacco cigarette and e-cigarettes
    • Farsalinos K. E., Yannovits N., Sarri T., Voudris V., Poulas K. Nicotine delivery to the aerosol of a heat-not-burn tobacco product: comparison with a tobacco cigarette and e-cigarettes. Nicotine Tob Res 2017; https://doi.org/10.1093/ntr/ntx138
    • (2017) Nicotine Tob Res
    • Farsalinos, K.E.1    Yannovits, N.2    Sarri, T.3    Voudris, V.4    Poulas, K.5
  • 10
    • 85029284554 scopus 로고    scopus 로고
    • Comparison of chemicals in mainstream smoke in heat-not-burn tobacco and combustion cigarettes
    • Bekki K., Inaba Y., Uchiyama S., Kunugita N. Comparison of chemicals in mainstream smoke in heat-not-burn tobacco and combustion cigarettes. J Univ Occup Environ Hygeine 2017; 39: 201–207
    • (2017) J Univ Occup Environ Hygeine , vol.39 , pp. 201-207
    • Bekki, K.1    Inaba, Y.2    Uchiyama, S.3    Kunugita, N.4
  • 12
    • 84859834156 scopus 로고    scopus 로고
    • Use of hazard indices for a theoretical evaluation of cigarette smoke composition
    • Haussmann H. J. Use of hazard indices for a theoretical evaluation of cigarette smoke composition. Chem Res Toxicol 2012; 25: 794–810
    • (2012) Chem Res Toxicol , vol.25 , pp. 794-810
    • Haussmann, H.J.1
  • 13
    • 84859646950 scopus 로고    scopus 로고
    • Urinary levels of volatile organic carcinogen and toxicant biomarkers in relation to lung cancer development in smokers
    • Yuan J.-M., Gao Y.-T., Wang R., Chen M., Carmella S. G., Hecht S. S. Urinary levels of volatile organic carcinogen and toxicant biomarkers in relation to lung cancer development in smokers. Carcinogenesis 2012; 33: 804–809
    • (2012) Carcinogenesis , vol.33 , pp. 804-809
    • Yuan, J.-M.1    Gao, Y.-T.2    Wang, R.3    Chen, M.4    Carmella, S.G.5    Hecht, S.S.6
  • 14
    • 84863506167 scopus 로고    scopus 로고
    • Acrolein effects in pulmonary cells: relevance to chronic obstructive pulmonary disease
    • Moretto N., Volpi G., Pastore F., Facchinetti F. Acrolein effects in pulmonary cells: relevance to chronic obstructive pulmonary disease. Ann NY Acad Sci 2012; 1259: 39–46
    • (2012) Ann NY Acad Sci , vol.1259 , pp. 39-46
    • Moretto, N.1    Volpi, G.2    Pastore, F.3    Facchinetti, F.4
  • 16
    • 0036853540 scopus 로고    scopus 로고
    • Acetaldehyde in mainstream tobacco smoke: formation and occurrence in smoke and bioavailability in the smoker
    • Seeman J. I., Dixon M., Haussmann H. J. Acetaldehyde in mainstream tobacco smoke: formation and occurrence in smoke and bioavailability in the smoker. Chem Res Toxicol 2002; 15: 1331–1350
    • (2002) Chem Res Toxicol , vol.15 , pp. 1331-1350
    • Seeman, J.I.1    Dixon, M.2    Haussmann, H.J.3
  • 17
    • 19744380118 scopus 로고    scopus 로고
    • Pyrolysis of saccharide tobacco ingredients: a TGA–FTIR investigation
    • Baker R. R., Coburn S., Liu C., Teteh J. Pyrolysis of saccharide tobacco ingredients: a TGA–FTIR investigation. J Anal Appl Pyrolysis 2005; 74: 171–180
    • (2005) J Anal Appl Pyrolysis , vol.74 , pp. 171-180
    • Baker, R.R.1    Coburn, S.2    Liu, C.3    Teteh, J.4
  • 18
    • 84936955095 scopus 로고    scopus 로고
    • E-cigarettes generate high levels of aldehydes only in ‘dry puff’ conditions
    • Farsalinos K. E., Voudris V., Poulas K. E-cigarettes generate high levels of aldehydes only in ‘dry puff’ conditions. Addiction 2015; 110: 1352–1356
    • (2015) Addiction , vol.110 , pp. 1352-1356
    • Farsalinos, K.E.1    Voudris, V.2    Poulas, K.3
  • 19
    • 84953310428 scopus 로고    scopus 로고
    • Effect of variable power levels on the yield of total aerosol mass and formation of aldehydes in e-cigarette aerosols
    • Gillman I. G., Kistler K. A., Stewart E. W., Paolantonio A. R. Effect of variable power levels on the yield of total aerosol mass and formation of aldehydes in e-cigarette aerosols. Regul Toxicol Pharmacol 2016; 75: 58–65
    • (2016) Regul Toxicol Pharmacol , vol.75 , pp. 58-65
    • Gillman, I.G.1    Kistler, K.A.2    Stewart, E.W.3    Paolantonio, A.R.4
  • 20
    • 84893908308 scopus 로고    scopus 로고
    • Levels of selected carcinogens and toxicants in vapour from electronic cigarettes
    • Goniewicz M. L., Knysak J., Gawron M., Kosmider L., Sobczak A., Kurek J. et al. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob Control 2014; 23: 133–139
    • (2014) Tob Control , vol.23 , pp. 133-139
    • Goniewicz, M.L.1    Knysak, J.2    Gawron, M.3    Kosmider, L.4    Sobczak, A.5    Kurek, J.6
  • 21
    • 84960500198 scopus 로고    scopus 로고
    • Correlation of volatile carbonyl yields emitted by e-cigarettes with the temperature of the heating coil and the perceived sensorial quality of the generated vapours
    • Geiss O., Bianchi I., Barrero-Moreno J. Correlation of volatile carbonyl yields emitted by e-cigarettes with the temperature of the heating coil and the perceived sensorial quality of the generated vapours. Int J Hyg Environ Health 2016; 219: 268–277
    • (2016) Int J Hyg Environ Health , vol.219 , pp. 268-277
    • Geiss, O.1    Bianchi, I.2    Barrero-Moreno, J.3
  • 23
    • 85009099952 scopus 로고    scopus 로고
    • Flavoring compounds dominate toxic aldehyde production during E-cigarette vaping
    • Khlystov A., Samburova V. Flavoring compounds dominate toxic aldehyde production during E-cigarette vaping. Environ Sci Technol 2016; 50: 13080–13085
    • (2016) Environ Sci Technol , vol.50 , pp. 13080-13085
    • Khlystov, A.1    Samburova, V.2
  • 24
    • 84985991232 scopus 로고    scopus 로고
    • Emissions from electronic cigarettes: key parameters affecting the release of harmful chemicals
    • Sleiman M., Logue J. M., Montesinos V. N., Russell M. L., Litter M. I., Gundel L. A. et al. Emissions from electronic cigarettes: key parameters affecting the release of harmful chemicals. Environ Sci Technol 2016; 50: 9644–9651
    • (2016) Environ Sci Technol , vol.50 , pp. 9644-9651
    • Sleiman, M.1    Logue, J.M.2    Montesinos, V.N.3    Russell, M.L.4    Litter, M.I.5    Gundel, L.A.6
  • 26
    • 85028592110 scopus 로고    scopus 로고
    • E-cigarettes emit very high formaldehyde levels only in conditions that are aversive to users: a replication study under verified realistic use conditions
    • Farsalinos K. E., Voudris V., Spyrou A., Poulas K. E-cigarettes emit very high formaldehyde levels only in conditions that are aversive to users: a replication study under verified realistic use conditions. Food Chem Toxicol 2017; 109: 90–94
    • (2017) Food Chem Toxicol , vol.109 , pp. 90-94
    • Farsalinos, K.E.1    Voudris, V.2    Spyrou, A.3    Poulas, K.4
  • 27
    • 85033411400 scopus 로고    scopus 로고
    • Aldehyde levels in e-cigarette aerosol: findings from a replication study and from use of a new-generation device
    • Farsalinos K. E., Kistler K. A., Pennington A., Spyrou A., Kouretas D., Gillman G. Aldehyde levels in e-cigarette aerosol: findings from a replication study and from use of a new-generation device. Food Chem Toxicol 2017; 111: 64–70
    • (2017) Food Chem Toxicol , vol.111 , pp. 64-70
    • Farsalinos, K.E.1    Kistler, K.A.2    Pennington, A.3    Spyrou, A.4    Kouretas, D.5    Gillman, G.6
  • 28
    • 84922465363 scopus 로고    scopus 로고
    • (accessed 19 October 2017) (Archived at, on 3 July 2018)., http://www.webcitation.org/70cjAkjfC
    • Cooperation Centre for Scientific Research Relative to Tobacco. CORESTA recommended method no. 75: determination of selected carbonyls in mainstream cigarette smoke by HPLC. 2013. Available at: http://www.coresta.org/Recommended_Methods/CRM_75.pdf (accessed 19 October 2017) (Archived at http://www.webcitation.org/70cjAkjfC on 3 July 2018)
    • (2013) CORESTA recommended method no. 75: determination of selected carbonyls in mainstream cigarette smoke by HPLC
  • 29
    • 84877673105 scopus 로고    scopus 로고
    • ‘Vaping’ profiles and preferences: an online survey of electronic cigarette users
    • Dawkins L., Turner J., Roberts A., Soar K. ‘Vaping’ profiles and preferences: an online survey of electronic cigarette users. Addiction 2013; 108: 1115–1125
    • (2013) Addiction , vol.108 , pp. 1115-1125
    • Dawkins, L.1    Turner, J.2    Roberts, A.3    Soar, K.4
  • 31
    • 85045190314 scopus 로고    scopus 로고
    • Electronic cigarettes: an aid in smoking cessation, or a new health hazard?
    • 1753465817744960
    • Farsalinos K. Electronic cigarettes: an aid in smoking cessation, or a new health hazard? Ther Adv Respir Dis 2018; 12: 1753465817744960. https://doi.org/10.1177/1753465817744960
    • (2018) Ther Adv Respir Dis , vol.12
    • Farsalinos, K.1
  • 32
    • 85006921186 scopus 로고    scopus 로고
    • Evaluation of the tobacco heating system 2.2. Part 8: 5-day randomized reduced exposure clinical study in Poland
    • Haziza C., de La Bourdonnaye G., Skiada D., Ancerewicz J., Baker G., Picavet P. et al. Evaluation of the tobacco heating system 2.2. Part 8: 5-day randomized reduced exposure clinical study in Poland. Regul Toxicol Pharmacol 2016; 81: S139–50
    • (2016) Regul Toxicol Pharmacol , vol.81 , pp. S139-S150
    • Haziza, C.1    de La Bourdonnaye, G.2    Skiada, D.3    Ancerewicz, J.4    Baker, G.5    Picavet, P.6
  • 33
    • 14644390892 scopus 로고    scopus 로고
    • Smoke composition and predicting relationships for international commercial cigarettes smoked with three machine-smoking conditions
    • Counts M. E., Morton M. J., Laffoon S. W., Cox R. H., Lipowicz P. J. Smoke composition and predicting relationships for international commercial cigarettes smoked with three machine-smoking conditions. Regul Toxicol Pharmacol 2005; 41: 185–227
    • (2005) Regul Toxicol Pharmacol , vol.41 , pp. 185-227
    • Counts, M.E.1    Morton, M.J.2    Laffoon, S.W.3    Cox, R.H.4    Lipowicz, P.J.5
  • 34
    • 84857291872 scopus 로고    scopus 로고
    • Inventing conflicts of interest: a history of tobacco industry tactics
    • Brandt A. M. Inventing conflicts of interest: a history of tobacco industry tactics. Am J Public Health 2012; 102: 63–71
    • (2012) Am J Public Health , vol.102 , pp. 63-71
    • Brandt, A.M.1
  • 35
    • 33644661386 scopus 로고    scopus 로고
    • Secret science: tobacco industry research on smoking behaviour and cigarette toxicity
    • Hammond D., Collishaw N. E., Callard C. Secret science: tobacco industry research on smoking behaviour and cigarette toxicity. Lancet 2006; 367: 781–787
    • (2006) Lancet , vol.367 , pp. 781-787
    • Hammond, D.1    Collishaw, N.E.2    Callard, C.3
  • 36
    • 84964940761 scopus 로고    scopus 로고
    • Comparison of the pharmacokinetics of nicotine following single and ad libitum use of a tobacco heating system or combustible cigarettes
    • Picavet P., Haziza C., Lama N., Weitkunat R., Lüdicke F. Comparison of the pharmacokinetics of nicotine following single and ad libitum use of a tobacco heating system or combustible cigarettes. Nicotine Tob Res 2016; 18: 557–563
    • (2016) Nicotine Tob Res , vol.18 , pp. 557-563
    • Picavet, P.1    Haziza, C.2    Lama, N.3    Weitkunat, R.4    Lüdicke, F.5
  • 37
    • 85026634891 scopus 로고    scopus 로고
    • Nicotine pharmacokinetic profiles of the tobacco heating system 2.2, cigarettes and nicotine gum in Japanese smokers
    • Brossard P., Weitkunat R., Poux V., Lama N., Haziza C., Picavet P. et al. Nicotine pharmacokinetic profiles of the tobacco heating system 2.2, cigarettes and nicotine gum in Japanese smokers. Regul Toxicol Pharmacol 2017; 89: 193–199
    • (2017) Regul Toxicol Pharmacol , vol.89 , pp. 193-199
    • Brossard, P.1    Weitkunat, R.2    Poux, V.3    Lama, N.4    Haziza, C.5    Picavet, P.6
  • 38
    • 85044151029 scopus 로고    scopus 로고
    • Do flavouring compounds contribute to aldehyde emissions in e-cigarettes?
    • Farsalinos K. E., Voudris V. Do flavouring compounds contribute to aldehyde emissions in e-cigarettes? Food Chem Toxicol 2018; 115: 212–217
    • (2018) Food Chem Toxicol , vol.115 , pp. 212-217
    • Farsalinos, K.E.1    Voudris, V.2
  • 39
    • 85040446123 scopus 로고    scopus 로고
    • Carbonyl emissions in E-cigarette aerosol: a systematic review and methodological considerations
    • Farsalinos K. E., Gillman G. Carbonyl emissions in E-cigarette aerosol: a systematic review and methodological considerations. Front Physiol 2018; 8: 1119
    • (2018) Front Physiol , vol.8 , pp. 1119
    • Farsalinos, K.E.1    Gillman, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.