Age at first birth in women is genetically associated with increased risk of schizophrenia

Scientific Reports

Volumn 8, Issue 1, 2018, Pages

  Ni, Guiyan ^a,b   Gratten, Jacob ^c   Wray, Naomi R ^c   Lee, Sang Hong ^a,b,c   Ripke, Stephan ^d,e   Neale, Benjamin M ^d,e   Corvin, Aiden ^f   Walters, James T R ^g   Farh, Kai How ^d   Holmans, Peter A ^g   Lee, Phil ^d,e   Bulik Sullivan, Brendan ^d,e   Collier, David A ^h,i   Huang, Hailiang ^d,e   Pers, Tune H ^e,j,k   Agartz, Ingrid ^l,m,n   Agerbo, Esben ^o,p   Albus, Margot ^q   Alexander, Madeline ^r   Amin, Farooq ^s,t   Bacanu, Silviu A ^u   Begemann, Martin ^v   Belliveau, Richard A ^e   Bene, Judit ^w   Bergen, Sarah E ^e,l   Bevilacqua, Elizabeth ^e   Bigdeli, Tim B ^u   Black, Donald W ^x   Bruggeman, Richard ^y   Buccola, Nancy G ^z   Buckner, Randy L ^d,aa   Byerley, William ^ab   Cahn, Wiepke ^ac   Cai, Guiqing ^ad   Campion, Dominique ^ae   Cantor, Rita M ^af   Carr, Vaughan J ^ag,ah   Carrera, Noa ^g   Catts, Stanley V ^c,ag   Chambert, Kimberly D ^e   Chan, Raymond C K ^ai   Chen, Ronald Y L ^aj   Chen, Eric Y H ^aj,ak   Cheng, Wei ^al   Cheung, Eric F C ^am   Chong, Siow Ann ^an   Cloninger, C Robert ^ao   Cohen, David ^ap   Cohen, Nadine ^aq   Cormican, Paul ^f   Craddock, Nick ^g   Crowley, James J ^ar   Curtis, David ^as,at   Davidson, Michael ^au   Davis, Kenneth L ^ad   Degenhardt, Franziska ^av,aw   Del Favero, Jurgen ^ax   Demontis, Ditte ^o,p   Dikeos, Dimitris ^ay   Dinan, Timothy ^az   Djurovic, Srdjan ^n,ba   Donohoe, Gary ^f,bb   Drapeau, Elodie ^ad   Duan, Jubao ^bc,bd   Dudbridge, Frank ^be   Durmishi, Naser ^bf   Eichhammer, Peter ^bg   Eriksson, Johan ^bh,bi,bj   Escott Price, Valentina ^g   Essioux, Laurent ^bk   Fanous, Ayman H ^bl,bm,bn,bo   Farrell, Martilias S ^ar   Frank, Josef ^bp   Franke, Lude ^y   Freedman, Robert ^bq   Freimer, Nelson B ^br   Friedl, Marion ^bs   Friedman, Joseph I ^ad   Fromer, Menachem ^d,e,ad   Genovese, Giulio ^e   Georgieva, Lyudmila ^g   Giegling, Ina ^bs,bt   Giusti Rodríguez, Paola ^ar   Godard, Stephanie ^bu   Goldstein, Jacqueline I ^d,e   Golimbet, Vera ^bv   Gopal, Srihari ^bw   Haan, Lieuwe De ^bx   Hammer, Christian ^v   Hamshere, Marian L ^g   Hansen, Mark ^by   Hansen, Thomas ^p,bz   Haroutunian, Vahram ^ad,bo   Hartmann, Annette M ^bs   Henskens, Frans A ^ag,ca,cb   Herms, Stefan ^av,aw,cc   Hirschhorn, Joel N ^e,k,cd   Hoffmann, Per ^av,aw,cc   Hofman, Andrea ^av,aw   Hollegaard, Mads V ^ce   Hougaard, David M ^ce   Ikeda, Masashi ^cf   Joa, Inge ^cg   Juliá, Antonio ^ch   Kahn, René S ^ac   Kalaydjieva, Luba ^ci   Karachanak Yankova, Sena ^cj   Karjalainen, Juha ^y   Kavanagh, David ^g   Keller, Matthew C ^ck   Kennedy, James L ^cl,cm,cn   Khrunin, Andrey ^co   Kim, Yunjung ^ar   Klovins, Janis ^cp   Knowles, James A ^bm   Konte, Bettina ^bs   Kucinskas, Vaidutis ^cq   Kucinskiene, Zita Ausrele ^cq   Kuzelova Ptackova, Hana ^cr   Kähler, Anna K ^l   Laurent, Claudine ^r,cs   Keong, Jimmy Lee Chee ^an,ct   Legge, Sophie E ^g   Lerer, Bernard ^cu   Li, Miaoxin ^aj,ak,cv   Li, Tao ^cw   Liang, Kung Yee ^cx   Lieberman, Jeffrey ^cy   Limborska, Svetlana ^co   Loughland, Carmel M ^ag,cb   Lubinski, Jan ^cz   Lönnqvist, Jouko ^bj   Macek, Milan ^cr   Magnusson, Patrik K E ^l   Maher, Brion S ^cx   Maier, Wolfgang ^aw   Mallet, Jacques ^bu   Marsal, Sara ^ch   Mattheisen, Manuel ^o,p,aw   Mattingsdal, Morten ^n,da   McCarley, Robert W ^cd,db   McDonald, Colm ^bb   McIntosh, Andrew M ^dc   Meier, Sandra ^bp   Meijer, Carin J ^bx   Melegh, Bela ^w   Melle, Ingrid ^n,ba   Mesholam Gately, Raquelle I ^cd,dd   Metspalu, Andres ^de   Michie, Patricia T ^ag,cb   Milani, Lili ^de   Milanova, Vihra ^cj   Mokrab, Younes ^h   Morris, Derek W ^f,bb   Mors, Ole ^o,p,df   Murphy, Kieran C ^dg   Murray, Robin M ⁱ   Myin Germeys, Inez ^dh   Müller Myhsok, Bertram ^di,dj,dk   Nelis, Mari ^de   Nenadic, Igor ^dl   Nertney, Deborah A ^c   Nestadt, Gerald ^dm   Nicodemus, Kristin K ^f   Nikitina Zake, Liene ^cp   Nisenbaum, Laura ^h   Nordin, Annelie ^dn   O'callaghan, Eadbhard ^do   O'dushlaine, Colm ^e   O'neill, F Anthony ^dp   Oh, Sang Yun ^dq   Olincy, Ann ^bq   Olsen, Line ^p,bz   Os, Jim Van ^i,dh   Pantelis, Christos ^ag,dr   Papadimitriou, George N ^ay   Papiol, Sergi ^v   Parkhomenko, Elena ^ad   Pato, Michele T ^bm   Paunio, Tiina ^bj,ds   Pejovic Milovancevic, Milica ^dt   Perkins, Diana O ^ar   Pietiläinen, Olli ^bj,ds   Pimm, Jonathan ^at   Pocklington, Andrew J ^g   Powell, John ⁱ   Price, Alkes ^e,du   Pulver, Ann E ^dm   Purcell, Shaun M ^ad   Quested, Digby ^dv   Rasmussen, Henrik B ^p,bz   Reichenberg, Abraham ^ad   Reimers, Mark A ^u   Richards, Alexander L ^g   Roffman, Joshua L ^d   Roussos, Panos ^ad   Ruderfer, Douglas M ^g,ad   Salomaa, Veikko ^bj   Sanders, Alan R ^bc,bd   Schall, Ulrich ^ag,cb   Schubert, Christian R ^dw   Schulze, Thomas G ^bp,dx   Schwab, Sibylle G ^dy   Scolnick, Edward M ^e   Scott, Rodney J ^ag,cb,dz   Seidman, Larry J ^cd,dd   Shi, Jianxin ^ea   Sigurdsson, Engilbert ^eb   Silagadze, Teimuraz ^ec   Silverman, Jeremy M ^ad,bo   Sim, Kang ^an   Slominsky, Petr ^co   Smoller, Jordan W ^d,e   So, Hon Cheong ^aj   Spencer, Chris C A ^ed   Stahl, Eli A ^e,ad   Stefansson, Hreinn ^ee   Steinberg, Stacy ^ee   Stogmann, Elisabeth ^ef   Straub, Richard E ^eg   Strengman, Eric ^ac   Strohmaier, Jana ^bp   Stroup, T Scott ^cy   Subramaniam, Mythily ^an   Suvisaari, Jaana ^bj   Svrakic, Dragan M ^ao   Szatkiewicz, Jin P ^ar   Söderman, Erik ^l   Thirumalai, Srinivas ^eh   Toncheva, Draga ^cj   Tosato, Sarah ^ei   Veijola, Juha ^ej,ek   Waddington, John ^dg   Walsh, Dermot ^el   Wang, Dai ^bw   Wang, Qiang ^cw   Webb, Bradley T ^u   Weiser, Mark ^au   Wildenauer, Dieter B ^ci   Williams, Nigel M ^g   Williams, Stephanie ^ar   Witt, Stephanie H ^bp   Wolen, Aaron R ^u   Wong, Emily H M ^aj   Wormley, Brandon K ^u   Xi, Hualin Simon ^dw   Zai, Clement C ^cl,cm   Zheng, Xuebin ^em   Zimprich, Fritz ^ef   Stefansson, Kari ^ee   Visscher, Peter M ^c   Adolfsson, Rolf ^dn   Andreassen, Ole A ^n,ba   Blackwood, Douglas H R ^dc   Bramon, Elvira ^at   Buxbaum, Joseph D ^ad   Børglum, Anders D ^o,p,df   Cichon, Sven ^av,aw,cc,en   Darvasi, Ariel ^eo   Domenici, Enrico ^ep   Ehrenreich, Hannelore ^v   Esko, Tõnu ^e,k,cd,de   Gejman, Pablo V ^bc,bd   Gill, Michael ^f   Gurling, Hugh ^at   Hultman, Christina M ^l   Iwata, Nakao ^cf   Jablensky, Assen V ^ag,ci,eq   Jönsson, Erik G ^l,n   Kendler, Kenneth S ^u   Kirov, George ^g   Knight, Jo ^cl,cm,cn   Lencz, Todd ^er,es,et   Levinson, Douglas F ^r   Li, Qingqin S ^bw   Liu, Jianjun ^em,eu   Malhotra, Anil K ^er,es,et   McCarroll, Steven A ^e,cd   McQuillin, Andrew ^at   Moran, Jennifer L ^e   Mortensen, Preben B ^o,p   Mowry, Bryan J ^c,ad   Nöthen, Markus M ^av,aw   Ophoff, Roel A ^ac,af,br   Owen, Michael J ^g   Palotie, Aarno ^d,e,ds   Pato, Carlos N ^bm   Petryshen, Tracey L ^d,e,cd   Posthuma, Danielle ^ev,ew,ex   Rietschel, Marcella ^bp   Riley, Brien P ^u   Rujescu, Dan ^bs,bt   Sham, Pak C ^aj,ak,cv   Sklar, Pamela ^ad   Clair, David St ^ey   Weinberger, Daniel R ^dm,eg   Wendland, Jens R ^dw   Werge, Thomas ^p,bz,ez   Daly, Mark J ^d,e   Sullivan, Patrick F ^l,ar   O'donovan, Michael C ^g   more..

^a UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^b UNIVERSITY OF NEW ENGLAND   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^f TRINITY COLLEGE DUBLIN   (Ireland)

^g CARDIFF UNIVERSITY   (United Kingdom)

^h ELI LILLY AND COMPANY   (United States)

ⁱ KING'S COLLEGE LONDON   (United Kingdom)

^j TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^k BOSTON CHILDREN S HOSPITAL   (United States)

^l KAROLINSKA INSTITUTE   (Sweden)

^m DIAKONHJEMMET HOSPITAL   (Norway)

ⁿ UNIVERSITY OF OSLO   (Norway)

^o AARHUS UNIVERSITY   (Denmark)

^p IPSYCH   (Denmark)

^q KLINIKUM MÜNCHEN OST   (Germany)

^r STANFORD UNIVERSITY   (United States)

^s ATLANTA VA MEDICAL CENTER   (United States)

^t EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^u VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^v MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^w UNIVERSITY OF PÉCS   (Hungary)

^x UNIVERSITY OF IOWA   (United States)

^y UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^z LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^aa HARVARD UNIVERSITY   (United States)

^ab UNIVERSITY OF CALIFORNIA   (United States)

^ac UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^ad MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^ae INSERM   (France)

^af UNIVERSITY OF CALIFORNIA   (United States)

^ag SCHIZOPHRENIA RESEARCH INSTITUTE   (Australia)

^ah UNIVERSITY OF NEW SOUTH WALES   (Australia)

^ai INSTITUTE OF PSYCHOLOGY   (China)

^aj UNIVERSITY OF HONG KONG   (Hong Kong)

^ak UNIVERSITY OF HONG KONG   (Hong Kong)

^al UNIVERSITY OF NORTH CAROLINA   (United States)

^am CASTLE PEAK HOSPITAL   (Hong Kong)

^an INSTITUTE OF MENTAL HEALTH   (Singapore)

^ao WASHINGTON UNIVERSITY   (United States)

^ap ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^aq Blue Note Biosciences   (United States)

^ar UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^as QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^at UNIVERSITY COLLEGE LONDON   (United Kingdom)

^au SHEBA MEDICAL CENTER   (Israel)

^av Life and Brain Center   (Germany)

^aw UNIVERSITY OF BONN   (Germany)

^ax UNIVERSITY OF ANTWERP   (Belgium)

^ay UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^az UNIVERSITY COLLEGE CORK   (Ireland)

^ba OSLO UNIVERSITY HOSPITAL   (Norway)

^bb NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^bc UNIVERSITY OF CHICAGO   (United States)

^bd NORTHSHORE UNIVERSITY HEALTHSYSTEM   (United States)

^be LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^bf University Clinic of Psychiatry   (Macedonia)

^bg UNIVERSITY OF REGENSBURG   (Germany)

^bh HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^bi FOLKHÄLSAN RESEARCH CENTER   (Finland)

^bj NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^bk F HOFFMANN LA ROCHE LTD   (Switzerland)

^bl GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^bm UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^bn VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^bo VETERANS AFFAIRS MEDICAL CENTER   (United States)

^bp UNIVERSITY OF HEIDELBERG   (Germany)

^bq UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^br UNIVERSITY OF CALIFORNIA   (United States)

^bs MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^bt UNIVERSITY OF MUNICH   (Germany)

^bu PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^bv MENTAL HEALTH RESEARCH CENTER   (Russian Federation)

^bw JANSSEN RESEARCH AND DEVELOPMENT   (United States)

^bx ACADEMIC MEDICAL CENTER   (Netherlands)

^by ILLUMINA INC   (United States)

^bz Mental Health Centre Sct Hans   (Denmark)

^ca UNIVERSITY OF NEWCASTLE   (Australia)

^cb UNIVERSITY OF NEWCASTLE   (Australia)

^cc UNIVERSITY OF BASEL   (Switzerland)

^cd HARVARD MEDICAL SCHOOL   (United States)

^ce STATENS SERUM INSTITUT   (Denmark)

^cf FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^cg STAVANGER UNIVERSITY HOSPITAL   (Norway)

^ch HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^ci UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^cj MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

^ck UNIVERSITY OF COLORADO   (United States)

^cl CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^cm UNIVERSITY OF TORONTO   (Canada)

^cn UNIVERSITY OF TORONTO   (Canada)

^co INSTITUTE OF MOLECULAR GENETICS   (Russian Federation)

^cp LATVIAN BIOMEDICAL RESEARCH AND STUDY CENTRE   (Latvia)

^cq VILNIUS UNIVERSITY   (Lithuania)

^cr UNIVERSITY HOSPITAL MOTOL   (Czech Republic)

^cs SORBONNE UNIVERSITÉ   (France)

^ct DUKE NUS MEDICAL SCHOOL   (Singapore)

^cu HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^cv UNIVERSITY OF HONG KONG   (Hong Kong)

^cw SICHUAN UNIVERSITY   (China)

^cx JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^cy Och Spine at New York Presbyterian Hospitals   (United States)

^cz POMERANIAN MEDICAL UNIVERSITY   (Poland)

^da SØRLANDET HOSPITAL   (Norway)

^db Clinical Neuroscience Division   (United States)

^dc UNIVERSITY OF EDINBURGH   (United Kingdom)

^dd BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^de UNIVERSITY OF TARTU   (Estonia)

^df AARHUS UNIVERSITY HOSPITAL   (Denmark)

^dg ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^dh MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^di UNIVERSITY OF LIVERPOOL   (United Kingdom)

^dj MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^dk Germany 3 Munich Cluster for Systems Neurology   (Germany)

^dl JENA UNIVERSITY HOSPITAL   (Germany)

^dm JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^dn UMEÅ UNIVERSITY   (Sweden)

^do DETECT   (Ireland)

^dp QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^dq UNIVERSITY OF CALIFORNIA   (United States)

^dr UNIVERSITY OF MELBOURNE   (Australia)

^ds UNIVERSITY OF HELSINKI   (Finland)

^dt UNIVERSITY OF BELGRADE   (Serbia)

^du HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^dv UNIVERSITY OF OXFORD   (United Kingdom)

^dw PFIZER INC   (United States)

^dx UNIVERSITY OF GÖTTINGEN   (Germany)

^dy UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^dz Hunter New England Health Service   (Australia)

^ea NATIONAL CANCER INSTITUTE   (United States)

^eb UNIVERSITY OF ICELAND   (Iceland)

^ec TBILISI STATE MEDICAL UNIVERSITY   (Georgia)

^ed UNIVERSITY OF OXFORD   (United Kingdom)

^ee DECODE GENETICS   (Iceland)

^ef MEDICAL UNIVERSITY OF VIENNA   (Austria)

^eg LIEBER INSTITUTE FOR BRAIN DEVELOPMENT   (United States)

^eh BERKSHIRE HEALTHCARE NHS FOUNDATION TRUST   (United Kingdom)

^ei UNIVERSITY OF VERONA   (Italy)

^ej UNIVERSITY OF OULU   (Finland)

^ek OULU UNIVERSITY HOSPITAL   (Finland)

^el HEALTH RESEARCH BOARD   (Ireland)

^em GENOME INSTITUTE OF SINGAPORE   (Singapore)

^en FORSCHUNGSZENTRUM JÜLICH   (Germany)

^eo HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^ep F Hoffmann La Roche   (Switzerland)

^eq UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^er FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^es DONALD AND BARBARA ZUCKER SCHOOL OF MEDICINE AT HOFSTRA NORTHWELL   (United States)

^et ZUCKER HILLSIDE HOSPITAL   (United States)

^eu NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^ev ERASMUS MEDICAL CENTER   (Netherlands)

^ew VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^ex VU UNIVERSITY AMSTERDAM   (Netherlands)

^ey UNIVERSITY OF ABERDEEN   (United Kingdom)

^ez UNIVERSITY OF COPENHAGEN   (Denmark)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; BIRTH; FEMALE; GENETIC PREDISPOSITION; GENETICS; HUMAN; MATERNAL AGE; MULTIFACTORIAL INHERITANCE; PHYSIOLOGY; PREGNANCY; RISK FACTOR; SCHIZOPHRENIA;

ADULT; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MATERNAL AGE; MULTIFACTORIAL INHERITANCE; PARTURITION; PREGNANCY; RISK FACTORS; SCHIZOPHRENIA;

EID: 85049684948     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-018-28160-z     Document Type: Article

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