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Volumn 2, Issue 3, 2017, Pages

Clinical outcome and molecular characterisation of chemorefractory metastatic colorectal cancer patients with long-term efficacy of regorafenib treatment

Author keywords

biomarkers; epithelial mesenchymal transition; Her 2; long responders; metastatic colorectal cancer; regorafenib

Indexed keywords


EID: 85049521445     PISSN: None     EISSN: 20597029     Source Type: Journal    
DOI: 10.1136/esmoopen-2017-000177     Document Type: Article
Times cited : (29)

References (12)
  • 2
    • 84984985398 scopus 로고    scopus 로고
    • ESMO consensus guidelines for the management of patients with metastatic colorectal Cancer
    • Van Cutsem E, Cervantes A, Adam R, et al. ESMO consensus guidelines for the management of patients with metastatic colorectal Cancer. Ann Oncol 2016;27:1386-422.
    • (2016) Ann Oncol , vol.27 , pp. 1386-1422
    • Van Cutsem, E.1    Cervantes, A.2    Adam, R.3
  • 3
    • 79954499886 scopus 로고    scopus 로고
    • Regorafenib (BAY 73-4506): A new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity
    • Wilhelm SM, Dumas J, Adnane L, et al. Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity. Int J Cancer 2011;129:245-55.
    • (2011) Int J Cancer , vol.129 , pp. 245-255
    • Wilhelm, S.M.1    Dumas, J.2    Adnane, L.3
  • 4
    • 84872921660 scopus 로고    scopus 로고
    • Regorafenib monotherapy for previously treated metastatic colorectal Cancer (CORRECT): An international, multicentre, randomised, placebo-controlled, phase 3 trial
    • Grothey A, Van Cutsem E, Sobrero A, et al. Regorafenib monotherapy for previously treated metastatic colorectal Cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial. Lancet 2013;381:303-12.
    • (2013) Lancet , vol.381 , pp. 303-312
    • Grothey, A.1    Van Cutsem, E.2    Sobrero, A.3
  • 5
    • 84930276518 scopus 로고    scopus 로고
    • Regorafenib plus best supportive care versus placebo plus best supportive care in Asian patients with previously treated metastatic colorectal cancer (CONCUR): A randomised, double-blind, placebo-controlled, phase 3 trial
    • Li J, Qin S, Xu R, et al. Regorafenib plus best supportive care versus placebo plus best supportive care in Asian patients with previously treated metastatic colorectal cancer (CONCUR): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Oncol 2015;16:619-29.
    • (2015) Lancet Oncol , vol.16 , pp. 619-629
    • Li, J.1    Qin, S.2    Xu, R.3
  • 6
    • 84955683730 scopus 로고    scopus 로고
    • Results from the large, open-label phase 3b CONSIGN study of regorafenib in patients with previously treated metastatic colorectal cancer [abstract]
    • Van Cutsem E, Ciardiello F, Seitz J F, et al. Results from the large, open-label phase 3b CONSIGN study of regorafenib in patients with previously treated metastatic colorectal cancer [abstract]. Ann Oncol 2015.
    • (2015) Ann Oncol
    • Van Cutsem, E.1    Ciardiello, F.2    Seitz, J.F.3
  • 7
    • 84964653262 scopus 로고    scopus 로고
    • Angiogenesis genotyping and clinical outcome during regorafenib treatment in metastatic colorectal Cancer patients
    • Giampieri R, Salvatore L, Del Prete M, et al. Angiogenesis genotyping and clinical outcome during regorafenib treatment in metastatic colorectal Cancer patients. Sci Rep 2016;6:25195.
    • (2016) Sci Rep , vol.6 , pp. 25195
    • Giampieri, R.1    Salvatore, L.2    Del Prete, M.3
  • 8
    • 84946083938 scopus 로고    scopus 로고
    • Prognostic clinical factors in pretreated colorectal Cancer patients receiving regorafenib: Implications for clinical management6: 33982-92, 10.18632/
    • Del Prete M, Giampieri R, Loupakis F, et al. Prognostic clinical factors in pretreated colorectal Cancer patients receiving regorafenib: implications for clinical management6:33982-92, 10.18632/. Oncotarget 2015;6:591.
    • (2015) Oncotarget , vol.6 , pp. 591
    • Del Prete, M.1    Giampieri, R.2    Loupakis, F.3
  • 9
    • 84938055998 scopus 로고    scopus 로고
    • Analysis of circulating DNA and protein biomarkers to predict the clinical activity of regorafenib and assess prognosis in patients with metastatic colorectal Cancer: A retrospective, exploratory analysis of the CORRECT trial
    • Tabernero J, Lenz HJ, Siena S, et al. Analysis of circulating DNA and protein biomarkers to predict the clinical activity of regorafenib and assess prognosis in patients with metastatic colorectal Cancer: a retrospective, exploratory analysis of the CORRECT trial. Lancet Oncol 2015;16:937-48.
    • (2015) Lancet Oncol , vol.16 , pp. 937-948
    • Tabernero, J.1    Lenz, H.J.2    Siena, S.3
  • 10
    • 84943779809 scopus 로고    scopus 로고
    • Regorafenib-associated hand-foot skin reaction: Practical advice on diagnosis, prevention, and management
    • McLellan B, Ciardiello F, Lacouture ME, et al. Regorafenib-associated hand-foot skin reaction: practical advice on diagnosis, prevention, and management. Ann Oncol 2015;26:2017-26.
    • (2015) Ann Oncol , vol.26 , pp. 2017-2026
    • McLellan, B.1    Ciardiello, F.2    Lacouture, M.E.3
  • 11
    • 84943411277 scopus 로고    scopus 로고
    • AXL is an oncotarget in human colorectal Cancer
    • Martinelli E, Martini G, Cardone C, et alAXL is an oncotarget in human colorectal Cancer. Oncotarget 2015;6:23281-96.
    • (2015) Oncotarget , vol.6 , pp. 23281-23296
    • Martinelli, E.1    Martini, G.2    Cardone, C.3
  • 12
    • 84944716890 scopus 로고    scopus 로고
    • Molecular subtypes and outcomes in regorafenib-treated patients with metastatic colorectal Cancer (mCRC) enrolled in the CORRECT trial. [abstr 3558]
    • Teufel M, Schwenke S, Seidel H, et al. Molecular subtypes and outcomes in regorafenib-treated patients with metastatic colorectal Cancer (mCRC) enrolled in the CORRECT trial. [abstr 3558]. J Clin Oncol 2015.
    • (2015) J Clin Oncol
    • Teufel, M.1    Schwenke, S.2    Seidel, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.