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Volumn 6, Issue 27, 2015, Pages 23281-23296

AXL is an oncotarget in human colorectal cancer

Author keywords

AXL; Colorectal cancer; FISH; Foretinib; GAS6

Indexed keywords

AXL PROTEIN; GROWTH ARREST SPECIFIC PROTEIN 6; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN S6; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG; ANILIDE; ANTINEOPLASTIC AGENT; AXL RECEPTOR TYROSINE KINASE; FORETINIB; GROWTH ARREST-SPECIFIC PROTEIN 6; ONCOPROTEIN; PROTEIN TYROSINE KINASE; QUINOLINE DERIVATIVE; SIGNAL PEPTIDE;

EID: 84943411277     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3962     Document Type: Article
Times cited : (56)

References (40)
  • 4
    • 84911474269 scopus 로고    scopus 로고
    • Metastatic colorectal cancer:ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    • Van Cutsem E, Cervantes A, Nordlinger B & Arnold D, on behalf of the ESMO Guidelines Working Group. Metastatic colorectal cancer:ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol (2014) 25 (suppl 3).
    • (2014) Ann Oncol , vol.25
    • Van Cutsem, E.1    Cervantes, A.2    Nordlinger, B.3    Arnold, D.4
  • 7
    • 46449103344 scopus 로고    scopus 로고
    • TAM receptor tyrosine kinases:biologic functions, signaling, and potential therapeutic targeting in human cancer
    • Linger, R. Keating AK, Earp HS, Graham DK. TAM receptor tyrosine kinases:biologic functions, signaling, and potential therapeutic targeting in human cancer. Adv. Cancer Res. 2008;100:35-83.
    • (2008) Adv. Cancer Res , vol.100 , pp. 35-83
    • Linger, R.1    Keating, A.K.2    Earp, H.S.3    Graham, D.K.4
  • 8
    • 42649140235 scopus 로고    scopus 로고
    • Immunobiology of the TAM receptors
    • Lemke G, Rothlin CV. Immunobiology of the TAM receptors. Nat. Rev. Immunol. 2008;8:327-336.
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 327-336
    • Lemke, G.1    Rothlin, C.V.2
  • 12
    • 84910023966 scopus 로고    scopus 로고
    • Axl as a mediator of cellular growth and survival
    • Axelrod H, Pienta KJ. Axl as a mediator of cellular growth and survival. Oncotarget. 2014;5:8818-52.
    • (2014) Oncotarget , vol.5 , pp. 8818-8852
    • Axelrod, H.1    Pienta, K.J.2
  • 19
    • 78149250536 scopus 로고    scopus 로고
    • Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer:the PRIME study
    • Douillard JY, Siena S, Cassidy J, Tabernero J, Burkes R, Barugel M, Humblet Y, Bodoky G, Cunningham D, Jassem J, Rivera F, Kocákova I, Ruff P, et al. Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer:the PRIME study. J Clin Oncol 2010;28:4697-4705.
    • (2010) J Clin Oncol , vol.28 , pp. 4697-4705
    • Douillard, J.Y.1    Siena, S.2    Cassidy, J.3    Tabernero, J.4    Burkes, R.5    Barugel, M.6    Humblet, Y.7    Bodoky, G.8    Cunningham, D.9    Jassem, J.10    Rivera, F.11    Kocákova, I.12    Ruff, P.13
  • 21
    • 77949435827 scopus 로고    scopus 로고
    • Molecular Mechanisms of Resistance to Cetuximab and Panitumumab in Colorectal Cancer
    • Bardelli A, Siena S. Molecular Mechanisms of Resistance to Cetuximab and Panitumumab in Colorectal Cancer. J Clin Oncol 2010;8:1254-1261.
    • (2010) J Clin Oncol , vol.8 , pp. 1254-1261
    • Bardelli, A.1    Siena, S.2
  • 26
    • 84892819211 scopus 로고    scopus 로고
    • Higher expression of receptors tyrosine kinase Axl, and differential expression of its ligand, Gas6, predict poor survival in lung adenocarcinoma patients
    • Ishikawa M, Sonobe M, Nakayama E, Kobayashi M, Kikuchi R, Kitamura J. Higher expression of receptors tyrosine kinase Axl, and differential expression of its ligand, Gas6, predict poor survival in lung adenocarcinoma patients. Annals of surgical oncology. 2013;20:S467-476.
    • (2013) Annals of surgical oncology , vol.20 , pp. S467-S476
    • Ishikawa, M.1    Sonobe, M.2    Nakayama, E.3    Kobayashi, M.4    Kikuchi, R.5    Kitamura, J.6
  • 29
    • 84929573682 scopus 로고    scopus 로고
    • Targeting the degradation of AXL receptor tyrosine kinase to overcome resistance in gefitinib-resistant non-small cell lung cancer
    • Feb 26. [Epub ahead of print]
    • Bae SY, Hong JY, Lee HJ, Park HJ, Lee SK. Targeting the degradation of AXL receptor tyrosine kinase to overcome resistance in gefitinib-resistant non-small cell lung cancer. Oncotarget. 2015 Feb 26. [Epub ahead of print].
    • (2015) Oncotarget
    • Bae, S.Y.1    Hong, J.Y.2    Lee, H.J.3    Park, H.J.4    Lee, S.K.5
  • 32
    • 84865839326 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions: insights from development
    • Lim J, Thiery JP. Epithelial-mesenchymal transitions: insights from development. Development. 2012;139:3471-3486.
    • (2012) Development , vol.139 , pp. 3471-3486
    • Lim, J.1    Thiery, J.P.2
  • 37
    • 84892724318 scopus 로고    scopus 로고
    • MET and AXL inhibitor NPS-1034 exerts efficacy against lung cancer cells resistant to EGFR kinase inhibitors because of MET or AXL activation
    • Rho JK, Choi YJ, Kim SY, Kim TW, Choi EK, Yoon SJ, Park BM, Park E, Bae JH, Choi CM, Lee JC. MET and AXL inhibitor NPS-1034 exerts efficacy against lung cancer cells resistant to EGFR kinase inhibitors because of MET or AXL activation. Cancer Res. 2014 74:253-66.
    • (2014) Cancer Res , vol.74 , pp. 253-266
    • Rho, J.K.1    Choi, Y.J.2    Kim, S.Y.3    Kim, T.W.4    Choi, E.K.5    Yoon, S.J.6    Park, B.M.7    Park, E.8    Bae, J.H.9    Choi, C.M.10    Lee, J.C.11
  • 38
    • 44949253112 scopus 로고    scopus 로고
    • Phosphorylation of Fibroblast Growth Factor (FGF) Receptor 1 at Ser777 by p38 Mitogen-Activated Protein Kinase Regulates Translocation of Exogenous FGF1 to the Cytosol and Nucleus
    • Sørensen V, Zhen Y, Zakrzewska M, Haugsten EM, Wälchli S, Nilsen T, Olsnes S, Wiedlocha A. Phosphorylation of Fibroblast Growth Factor (FGF) Receptor 1 at Ser777 by p38 Mitogen-Activated Protein Kinase Regulates Translocation of Exogenous FGF1 to the Cytosol and Nucleus. Molecular and cellular biology. 2008:4129-4141.
    • (2008) Molecular and cellular biology , pp. 4129-4141
    • Sørensen, V.1    Zhen, Y.2    Zakrzewska, M.3    Haugsten, E.M.4    Wälchli, S.5    Nilsen, T.6    Olsnes, S.7    Wiedlocha, A.8
  • 39
    • 0028900612 scopus 로고
    • Receptor tyrosine kinases expressed in metastatic colon cancer
    • Craven RJ. Receptor tyrosine kinases expressed in metastatic colon cancer. Int J. cancer. 1995;60:791-797.
    • (1995) Int J. cancer , vol.60 , pp. 791-797
    • Craven, R.J.1
  • 40
    • 84892158897 scopus 로고    scopus 로고
    • Axl is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early-stage colon cancer
    • Dunne PD, McArt DG, Blayney JK, Kalimutho M, Greer S, Wang T. Axl is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early-stage colon cancer. Clinical Cancer Res. 2014;20:164-175.
    • (2014) Clinical Cancer Res , vol.20 , pp. 164-175
    • Dunne, P.D.1    McArt, D.G.2    Blayney, J.K.3    Kalimutho, M.4    Greer, S.5    Wang, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.