메뉴 건너뛰기




Volumn 55, Issue 1, 2017, Pages 2170-2177

Momordica charantia extracts ameliorate insulin resistance by regulating the expression of socs-3 and jnk in type 2 diabetes mellitus rats

Author keywords

C Jun N terminal kinase; IL 6; Liver glycogen; Suppressor of cytokine signaling 3; TNF a

Indexed keywords

GLUCOSE; GLUCOSE TRANSPORTER 4; GLYCOGEN; INSULIN; INTERLEUKIN 6; MESSENGER RNA; METFORMIN; MOMORDICA CHARANTIA EXTRACT; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; SUPPRESSOR OF CYTOKINE SIGNALING 3; TUMOR NECROSIS FACTOR; ANTIDIABETIC AGENT; PLANT EXTRACT; SOCS3 PROTEIN, RAT; STREPTOZOCIN;

EID: 85049409746     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.1080/13880209.2017.1396350     Document Type: Article
Times cited : (54)

References (33)
  • 1
    • 34247395523 scopus 로고    scopus 로고
    • An update on the etiology and epidemiology of diabetes mellitus
    • Adeghate E, Schattner P, Dunn E. 2006. An update on the etiology and epidemiology of diabetes mellitus. Ann N Y Acad Sci. 1084:1–29.
    • (2006) Ann N Y Acad Sci , vol.1084 , pp. 1-29
    • Adeghate, E.1    Schattner, P.2    Dunn, E.3
  • 2
    • 84906705822 scopus 로고    scopus 로고
    • Anti-inflammatory effect of Momordica charantia in sepsis mice
    • Chao CY, Sung PJ, Wang WH, Kuo YH. 2014. Anti-inflammatory effect of Momordica charantia in sepsis mice. Molecules. 19:12777–12788.
    • (2014) Molecules , vol.19 , pp. 12777-12788
    • Chao, C.Y.1    Sung, P.J.2    Wang, W.H.3    Kuo, Y.H.4
  • 3
    • 11144233279 scopus 로고    scopus 로고
    • Effect of Momordica charantia on lipid profile and oral glucose tolerance in diabetic rats
    • Chaturvedi P, George S, Milinganyo M, Tripathi YB. 2004. Effect of Momordica charantia on lipid profile and oral glucose tolerance in diabetic rats. Phytother Res. 18:954–956.
    • (2004) Phytother Res , vol.18 , pp. 954-956
    • Chaturvedi, P.1    George, S.2    Milinganyo, M.3    Tripathi, Y.B.4
  • 4
    • 0037385896 scopus 로고    scopus 로고
    • Bitter melon (Momordica charantia) reduces adiposity, lowers serum insulin and normalizers glucose tolerance in rats fed a high fat diet
    • Chen Q, Chan LL, Li ET. 2003. Bitter melon (Momordica charantia) reduces adiposity, lowers serum insulin and normalizers glucose tolerance in rats fed a high fat diet. J Nutr. 133:1088–1093.
    • (2003) J Nutr , vol.133 , pp. 1088-1093
    • Chen, Q.1    Chan, L.L.2    Li, E.T.3
  • 6
    • 64549141112 scopus 로고    scopus 로고
    • Momordica charantia extract on insulin resistance and the skeletal muscle GLUT4 protein in fructose-fed rats
    • Chun CS, Cheng HL, Wei LL, Wu JB. 2009. Momordica charantia extract on insulin resistance and the skeletal muscle GLUT4 protein in fructose-fed rats. J Ethnopharmacol. 123:82–90.
    • (2009) J Ethnopharmacol , vol.123 , pp. 82-90
    • Chun, C.S.1    Cheng, H.L.2    Wei, L.L.3    Wu, J.B.4
  • 7
    • 84895781801 scopus 로고    scopus 로고
    • Momordica charantia ameliorates insulin resistance and dyslipidemia with altered hepatic glucose production and fatty acid synthesis and AMPK phosphorylation in high-fat-fed mice
    • Chun CS, Min TS, Cheng HL, Jin BW. 2014. Momordica charantia ameliorates insulin resistance and dyslipidemia with altered hepatic glucose production and fatty acid synthesis and AMPK phosphorylation in high-fat-fed mice. Phytother Res. 28:363–371.
    • (2014) Phytother Res , vol.28 , pp. 363-371
    • Chun, C.S.1    Min, T.S.2    Cheng, H.L.3    Jin, B.W.4
  • 8
    • 79151478555 scopus 로고    scopus 로고
    • Type 2 diabetes as an inflammatory disease
    • Donath MY, Shoelson SE. 2011. Type 2 diabetes as an inflammatory disease. Nat Rev Immunol. 11:98–107.
    • (2011) Nat Rev Immunol , vol.11 , pp. 98-107
    • Donath, M.Y.1    Shoelson, S.E.2
  • 9
    • 84896859556 scopus 로고    scopus 로고
    • Potential for improved glycemic control with dietary Momordica charantia in patients with insulin resistance and pre-diabetes
    • Efird JT, Choi YM, Davies SW, Mehra S, Anderson EJ, Katunga LA. 2014. Potential for improved glycemic control with dietary Momordica charantia in patients with insulin resistance and pre-diabetes. Int J Environ Res Public Health. 11:2328–2345.
    • (2014) Int J Environ Res Public Health , vol.11 , pp. 2328-2345
    • Efird, J.T.1    Choi, Y.M.2    Davies, S.W.3    Mehra, S.4    Anderson, E.J.5    Katunga, L.A.6
  • 10
    • 84874155560 scopus 로고    scopus 로고
    • Reliability of HOMA-IR for evaluation of insulin resistance during peri-operative period
    • Fujino H, Itoda S, Sako S, Matsuo K, Sakamoto E, Yokoyama T. 2013. Reliability of HOMA-IR for evaluation of insulin resistance during peri-operative period. Masui. 62:140–146.
    • (2013) Masui , vol.62 , pp. 140-146
    • Fujino, H.1    Itoda, S.2    Sako, S.3    Matsuo, K.4    Sakamoto, E.5    Yokoyama, T.6
  • 11
    • 84903291617 scopus 로고    scopus 로고
    • Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity
    • Galic S, Sachithanandan N, Kay TW, Steinberg GR. 2014. Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity. Biochem J. 461:177–188.
    • (2014) Biochem J , vol.461 , pp. 177-188
    • Galic, S.1    Sachithanandan, N.2    Kay, T.W.3    Steinberg, G.R.4
  • 12
    • 84897427505 scopus 로고    scopus 로고
    • Momordica charantia and type 2 diabetes: From in vitro to human studies
    • Habicht SD, Ludwig C, Yang RY, Krawinkel MB. 2014. Momordica charantia and type 2 diabetes: from in vitro to human studies. Curr Diabetes Rev. 10:48–60.
    • (2014) Curr Diabetes Rev , vol.10 , pp. 48-60
    • Habicht, S.D.1    Ludwig, C.2    Yang, R.Y.3    Krawinkel, M.B.4
  • 13
    • 77953644854 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha (TNF-alpha) inhibits insulin-like growth factor-I (IGF-I) activities in human trophoblast cell cultures through IGF-I/insulin hybrid receptors
    • Hashimoto R, Sakai K, Matsumoto H, Iwashita M. 2010. Tumor necrosis factor-alpha (TNF-alpha) inhibits insulin-like growth factor-I (IGF-I) activities in human trophoblast cell cultures through IGF-I/insulin hybrid receptors. Endocr J. 57:193–200.
    • (2010) Endocr J , vol.57 , pp. 193-200
    • Hashimoto, R.1    Sakai, K.2    Matsumoto, H.3    Iwashita, M.4
  • 14
    • 84869418296 scopus 로고    scopus 로고
    • Binding Energy calculation of GSK-3 protein of Human against some anti-diabetic compounds of Momordica charantia linn (Bitter melon)
    • Hazarika R, Parida P, Neog B, Yadav RNS. 2012. Binding Energy calculation of GSK-3 protein of Human against some anti-diabetic compounds of Momordica charantia linn (Bitter melon). Bioinformation. 8:251–254.
    • (2012) Bioinformation , vol.8 , pp. 251-254
    • Hazarika, R.1    Parida, P.2    Neog, B.3    Yadav, R.N.S.4
  • 16
    • 36549059075 scopus 로고    scopus 로고
    • Inhibition of the protein tyrosine phosphatase PTP-1B: Potential therapy for obesity, insulin resistance and type-2 diabetes mellitus
    • Koren S, Fantus G. 2007. Inhibition of the protein tyrosine phosphatase PTP-1B: potential therapy for obesity, insulin resistance and type-2 diabetes mellitus. Best Pract Res Clin Endocrinol Metab. 21:621–640.
    • (2007) Best Pract Res Clin Endocrinol Metab , vol.21 , pp. 621-640
    • Koren, S.1    Fantus, G.2
  • 17
    • 70449687888 scopus 로고    scopus 로고
    • Fruit extracts of Momordica charantia potentiate glucose uptake and up-regulate Glut-4, PPAR gamma and PI3K
    • Kumar R, Balaji S, Uma TS, Sehgal PK. 2009. Fruit extracts of Momordica charantia potentiate glucose uptake and up-regulate Glut-4, PPAR gamma and PI3K. J Ethnopharmacol. 126:533–537.
    • (2009) J Ethnopharmacol , vol.126 , pp. 533-537
    • Kumar, R.1    Balaji, S.2    Uma, T.S.3    Sehgal, P.K.4
  • 18
    • 84880974817 scopus 로고    scopus 로고
    • Adipokines mediate inflammation and insulin resistance
    • Kwon H, Pessin JE. 2013. Adipokines mediate inflammation and insulin resistance. Front Endocrinol (Lausanne). 4:71.
    • (2013) Front Endocrinol (Lausanne) , vol.4 , pp. 71
    • Kwon, H.1    Pessin, J.E.2
  • 19
    • 74949111350 scopus 로고    scopus 로고
    • Anti-diabetic and hypoglycaemic effects of Momordica charantia (Bitter melon): A mini review
    • Leung L, Birtwhistle R, Kotecha J, Hannah S, Cuthbertson S. 2009. Anti-diabetic and hypoglycaemic effects of Momordica charantia (bitter melon): a mini review. Br J Nutr. 102:1703–1708.
    • (2009) Br J Nutr , vol.102 , pp. 1703-1708
    • Leung, L.1    Birtwhistle, R.2    Kotecha, J.3    Hannah, S.4    Cuthbertson, S.5
  • 20
    • 84893663418 scopus 로고    scopus 로고
    • Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance
    • Lee BC, Lee J. 2014. Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance. Biochim Biophys Acta. 1842:446–462.
    • (2014) Biochim Biophys Acta , vol.1842 , pp. 446-462
    • Lee, B.C.1    Lee, J.2
  • 23
    • 84855929671 scopus 로고    scopus 로고
    • Glycogen and its metabolism: Some new developments and old themes
    • Roach PJ, Depaoli RA, Hurley TD, Tagliabracci VS. 2012. Glycogen and its metabolism: some new developments and old themes. Biochem J. 441:763–787.
    • (2012) Biochem J , vol.441 , pp. 763-787
    • Roach, P.J.1    Depaoli, R.A.2    Hurley, T.D.3    Tagliabracci, V.S.4
  • 24
    • 38949119009 scopus 로고    scopus 로고
    • Sequential phosphorylation of insulin receptor substrate-2 by glycogen synthase kinase-3 and c-Jun NH2-ter-minal kinase plays a role in hepatic insulin signaling
    • Sharfi H, Eldar-Finkelman H. 2008. Sequential phosphorylation of insulin receptor substrate-2 by glycogen synthase kinase-3 and c-Jun NH2-ter-minal kinase plays a role in hepatic insulin signaling. Am J Physiol Endocrinol Metab. 294:307–315.
    • (2008) Am J Physiol Endocrinol Metab , vol.294 , pp. 307-315
    • Sharfi, H.1    Eldar-Finkelman, H.2
  • 25
    • 84925297031 scopus 로고    scopus 로고
    • Caulerpa lentillifera extract ameliorates insulin resistance and regulates glucose metabolism in C57BL/KsJ-db/db mice via PI3K/AKT signaling pathway in myocytes
    • Sharma BR, Kim HJ, Rhyu DY. 2015. Caulerpa lentillifera extract ameliorates insulin resistance and regulates glucose metabolism in C57BL/KsJ-db/db mice via PI3K/AKT signaling pathway in myocytes. J Transl Med. 13:62.
    • (2015) J Transl Med , vol.13 , pp. 62
    • Sharma, B.R.1    Kim, H.J.2    Rhyu, D.Y.3
  • 26
    • 4544256147 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling
    • Shi H, Tzameli I, Bjorbaek C, Flier JS. 2004. Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling. J Biol Chem. 279:34733–34740.
    • (2004) J Biol Chem , vol.279 , pp. 34733-34740
    • Shi, H.1    Tzameli, I.2    Bjorbaek, C.3    Flier, J.S.4
  • 27
    • 84927635080 scopus 로고    scopus 로고
    • Preventive effects of bitter melon (Momordica charantia) against insulin resistance and diabetes are associated with the inhibition of NF-jB and JNK pathways in high-fat-fed OLETF rats
    • Soo JY, Jung MC, Se EP, Eun JR, Won YL, Ki WO, Sung WP, Cheol YP. 2015. Preventive effects of bitter melon (Momordica charantia) against insulin resistance and diabetes are associated with the inhibition of NF-jB and JNK pathways in high-fat-fed OLETF rats. J Nutr Biochem. 26:234–240.
    • (2015) J Nutr Biochem , vol.26 , pp. 234-240
    • Soo, J.Y.1    Jung, M.C.2    Se, E.P.3    Eun, J.R.4    Won, Y.L.5    Ki, W.O.6    Sung, W.P.7    Cheol, Y.P.8
  • 29
    • 84890284142 scopus 로고    scopus 로고
    • PI3 kinase directly phosphorylates Akt1/2 at Ser473/474 in the insulin signal transduction pathway
    • Tsuchiya A, Kanno T, Nishizaki T. 2014. PI3 kinase directly phosphorylates Akt1/2 at Ser473/474 in the insulin signal transduction pathway. J Endocrinol. 220:49–59.
    • (2014) J Endocrinol , vol.220 , pp. 49-59
    • Tsuchiya, A.1    Kanno, T.2    Nishizaki, T.3
  • 30
    • 84856431865 scopus 로고    scopus 로고
    • TNFa increases hypothalamic PTP-1B activity via the NF jB pathway in rat hypothalamic organotypic cultures
    • Yoshihiro I, Ryoichi B, Shigeru H, Ozawa Y, Arima H, Oiso Y. 2012. TNFa increases hypothalamic PTP-1B activity via the NF jB pathway in rat hypothalamic organotypic cultures. Regul Pept. 174:58–64.
    • (2012) Regul Pept , vol.174 , pp. 58-64
    • Yoshihiro, I.1    Ryoichi, B.2    Shigeru, H.3    Ozawa, Y.4    Arima, H.5    Oiso, Y.6
  • 31
    • 0036710280 scopus 로고    scopus 로고
    • Irs proteins and the common path to diabetes
    • White MF. 2002. Irs proteins and the common path to diabetes. Am J Physiol Endocrinol Metab. 3:413–422.
    • (2002) Am J Physiol Endocrinol Metab , vol.3 , pp. 413-422
    • White, M.F.1
  • 32
    • 0347093460 scopus 로고    scopus 로고
    • Inhibitors of cytokine signal transduction
    • Wormald S, Hilton DJ. 2004. Inhibitors of cytokine signal transduction. J Biol Chem. 279:821–824.
    • (2004) J Biol Chem , vol.279 , pp. 821-824
    • Wormald, S.1    Hilton, D.J.2
  • 33
    • 47249158048 scopus 로고    scopus 로고
    • Traditional Chinese medicine in treatment of metabolic syndrome
    • Yin J, Zhang H, Ye J. 2008. Traditional Chinese medicine in treatment of metabolic syndrome. Endocr Metab Immune Disord Drug Targets. 8:99–111.
    • (2008) Endocr Metab Immune Disord Drug Targets , vol.8 , pp. 99-111
    • Yin, J.1    Zhang, H.2    Ye, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.