Factors contributing to surgical site infection in patients with oral cancer undergoing microvascular free flap reconstruction

European Archives of Oto-Rhino-Laryngology

Volumn 275, Issue 8, 2018, Pages 2101-2108

  Lin, Sheng Chiao ^a   Chang, Ting Shou ^a,b   Yang, Kuo Chung ^a,c,d   Lin, Yaoh Shiang ^a,d   Lin, Yu Hsuan ^e  

^a KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^e NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Free tissue reconstruction; Oral cancer; Oro neck communication; Surgical site infection

Indexed keywords

ADULT; AGED; ARTICLE; CANCER PROGNOSIS; FEMALE; FREE TISSUE GRAFT; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MANDIBLE RESECTION; MOUTH CANCER; MOUTH CAVITY; POSTOPERATIVE PERIOD; PREDICTION; PRIORITY JOURNAL; RECONSTRUCTIVE SURGERY; RISK FACTOR; SURGICAL INFECTION; TERTIARY CARE CENTER; MIDDLE AGED; MOUTH TUMOR; OPERATION DURATION; ORAL SURGERY; RETROSPECTIVE STUDY; TAIWAN; VASCULARIZATION; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; FREE TISSUE FLAPS; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MOUTH NEOPLASMS; OPERATIVE TIME; ORAL SURGICAL PROCEDURES; RECONSTRUCTIVE SURGICAL PROCEDURES; RETROSPECTIVE STUDIES; RISK FACTORS; SURGICAL WOUND INFECTION; TAIWAN;

EID: 85048305889     PISSN: 09374477     EISSN: 14344726     Source Type: Journal    
DOI: 10.1007/s00405-018-5035-z     Document Type: Article

References (37)

1. Jemal A, Bray F, Center MM et al (2011) Global cancer statistics. CA Cancer J Clin 61:69–90
2. Parkin DMBF., Ferlay J, Pisani P (2005) Global cancer statistics, 2002. CA Cancer J Clin 55:74–108
3. Hanasono MM, Friel MT, Klem C et al (2009) Impact of reconstructive microsurgery in patients with advanced oral cavity cancers. Head neck 31:1289–1296
4. Bak M, Jacobson AS, Buchbinder D, Urken ML (2010) Contemporary reconstruction of the mandible. Oral Oncol 46:71–76
5. Belusic-Gobic M, Car M, Juretic M et al (2007) Risk factors for wound infection after oral cancer surgery. Oral Oncol 43:77–81
6. Kruse AL, Luebbers HT, Gratz KW, Obwegeser JA (2010) Factors influencing survival of free-flap in reconstruction for cancer of the head and neck: a literature review. Microsurgery 30:242–248
7. Penel N, Fournier C, Roussel-Delvallez M et al (2004) Prognostic significance of wound infections following major head and neck cancer surgery: an open non-comparative prospective study. Support Care Cancer 12:634–639
8. Grandis JR, Snyderman CH, Johnson JT et al (1992) Postoperative wound infection. A poor prognostic sign for patients with head and neck cancer. Cancer 70:2166–2170
9. Cunha TF, Soares Melancia TA, Zagalo Fernandes Ribeiro CM et al (2012) Risk factors for surgical site infection in cervico-facial oncological surgery. J Craniomaxillofac Surg 40:443–448
10. Wang CH, Wong YK, Wang CP et al (2015) Risk factors of recipient site infection in head and neck cancer patients undergoing pectoralis major myocutaneous flap reconstruction. Eur Arch Oto-Rhino-Laryngol 272:3475–3482
11. Ma CY, Ji T, Ow A et al (2012) Surgical site infection in elderly oral cancer patients: is the evaluation of comorbid conditions helpful in the identification of high-risk ones? J Oral Maxillofac Surg 70:2445–2452
12. Kamizono K, Sakuraba M, Nagamatsu S et al (2014) Statistical analysis of surgical site infection after head and neck reconstructive surgery. Ann Surg Oncol 21:1700–1705
13. Belusic-Gobic M, Zubovic A, Cerovic R et al (2018) Multivariate analysis of risk factors for postoperative wound infection following oral and oropharyngeal cancer surgery. J Craniomaxillofac Surg 46:135–141
14. Lee DH, Kim SY, Nam SY et al (2011) Risk factors of surgical site infection in patients undergoing major oncological surgery for head and neck cancer. Oral Oncol 47:528–531
15. Karakida K, Aoki T, Ota Y et al (2010) Analysis of risk factors for surgical-site infections in 276 oral cancer surgeries with microvascular free-flap reconstructions at a single university hospital. J Infect Chemother 16:334–339
16. Yarlagadda BB, Deschler DG, Rich DL et al (2016) Head and neck free flap surgical site infections in the era of the Surgical Care Improvement Project. Head neck 38(Suppl 1):E392–E398
17. Lee JI, Kwon M, Roh JL et al (2015) Postoperative hypoalbuminemia as a risk factor for surgical site infection after oral cancer surgery. Oral Dis 21:178–184
18. Eder-Czembirek C, Czembirek C, Braun P et al (2016) Surgical site infection in clean-contaminated wounds after multimodal treatment of advanced oral squamous cell carcinoma. J Craniomaxillofac Surg 44:1957–1962
19. Jain U, Somerville J, Saha S et al (2015) Oropharyngeal contamination predisposes to complications after neck dissection: an analysis of 9462 patients. Otolaryngol Head Neck Surg 153:71–78
20. Hirakawa H, Hasegawa Y, Hanai N et al (2013) Surgical site infection in clean-contaminated head and neck cancer surgery: risk factors and prognosis. Eur Arch Oto Rhino Laryngol 270:1115–1123
21. Lin YS, Liu WC, Chen LW, Yang KC (2013) Peroneal flap in hypopharyngeal reconstruction. Ann Surg Oncol 20:4356–4361
22. Liu WC, Yang KC (2015) One-stage through-and-through cheek, lips, and oral commissure reconstruction using a double-paddle peroneal chimeric flap: an innovative method. Head Neck 37:662–669
23. Agarwal JP, Agarwal S, Adler N, Gottlieb LJ (2009) Refining the intrinsic chimera flap: a review. Ann Plast Surg 63:462–467
24. Huang S-T, Liu W-C, Chen L-W, Yang K-C (2015) Oromandibular reconstruction with chimeric double-skin paddle flap based on peroneal vessel axis for synchronous opposite double oral cancer. Ann Plast Surg 74:S132–S138
25. Mangram AJ, Horan TC, Pearson ML et al (1999) Guideline for prevention of surgical site infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee. Am J Infect Control 27:97–132 (quiz 3–4; discussion 96)
26. Lotfi CJ, Cavalcanti Rde C, Costa e Silva AM et al (2008) Risk factors for surgical-site infections in head and neck cancer surgery. Otolaryngol Head Neck Surg 138:74–80
27. Munoz Guerra MF, Naval Gias L, Campo FR, Perez JS (2003) Marginal and segmental mandibulectomy in patients with oral cancer: a statistical analysis of 106 cases. J Oral Maxillofac Surg 61:1289–1296
28. Wei FC, Demirkan F, Chen HC, Chen IH (1999) Double free flaps in reconstruction of extensive composite mandibular defects in head and neck cancer. Plastic Reconstruct Surg 103:39–47
29. Leong G, Wilson J, Charlett A (2006) Duration of operation as a risk factor for surgical site infection: comparison of English and US data. J Hosp Infect 63:255–262
30. Culver DH, Horan TC, Gaynes RP et al (1991) Surgical wound infection rates by wound class, operative procedure, and patient risk index. National Nosocomial Infections Surveillance System. Am J Med 91:152s–157s
31. Sakuraba M, Miyamoto S, Kimata Y et al (2013) Recent advances in reconstructive surgery: head and neck reconstruction. Int J Clin Oncol 18:561–565
32. Bhama PK, Davis GE, Bhrany AD et al (2013) The effects of intensive care unit staffing on patient outcomes following microvascular free flap reconstruction of the head and neck: a pilot study. JAMA Otolaryngol Head Neck Surg 139:37–42
33. Panwar A, Smith R, Lydiatt D et al (2016) Vascularized tissue transfer in head and neck surgery: Is intensive care unit-based management necessary? The Laryngoscope 126:73–79
34. Arshad H, Ozer HG, Thatcher A et al (2014) Intensive care unit versus non-intensive care unit postoperative management of head and neck free flaps: comparative effectiveness and cost comparisons. Head Neck 36:536–539
35. Allak A, Nguyen TN, Shonka DC Jr et al (2011) Immediate postoperative extubation in patients undergoing free tissue transfer. The Laryngoscope 121:763–768
36. Chen WC, Hung KS, Chen SH et al (2018) Intensive care unit versus ward management after anterolateral thigh flap reconstruction after oral cancer ablation. Ann Plast Surg 80:S11–S14
37. Abt NB, Xie Y, Puram SV et al (2017) Frailty index: Intensive care unit complications in head and neck oncologic regional and free flap reconstruction. Head Neck 39:1578–1585