Oropharyngeal contamination predisposes to complications after neck dissection: An analysis of 9462 patients

Otolaryngology - Head and Neck Surgery (United States)

Volumn 153, Issue 1, 2015, Pages 71-78

  Jain, Umang ^a   Somerville, Jessica ^b   Saha, Sujata ^a   Hackett, Nicholas James ^a   Ver Halen, Jon P ^c   Antony, Anuja K ^d   Samant, Sandeep ^b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c VANDERBILT INGRAM CANCER CENTER   (United States)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

clean cases; contaminated cases; mortality; neck dissection; NSQIP; outcomes

Indexed keywords

ACUTE KIDNEY FAILURE; ADULT; ARTICLE; BLOOD TRANSFUSION; CEREBROVASCULAR ACCIDENT; CURRENT PROCEDURAL TERMINOLOGY; EPIDEMIOLOGY; FEMALE; GLOSSECTOMY; HEAD AND NECK CANCER; HEART ARREST; HUMAN; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; MANDIBLE RESECTION; MORTALITY; NECK DISSECTION; OROPHARYNGEAL CONTAMINATION; OUTCOME ASSESSMENT; PATIENT RISK; PHARYNX DISEASE; PNEUMONIA; POSTOPERATIVE COMPLICATION; REGRESSION ANALYSIS; REOPERATION; RETROSPECTIVE STUDY; RISK FACTOR; SEPTIC SHOCK; SURGEON; THYROIDECTOMY; TOTAL QUALITY MANAGEMENT; WOUND DEHISCENCE; WOUND INFECTION; ADVERSE EFFECTS; AGED; CLINICAL TRIAL; HEAD AND NECK NEOPLASMS; MIDDLE AGED; MOUTH; MULTICENTER STUDY; OROPHARYNX; PHARYNX; SECRETION (PROCESS); SURGICAL WOUND INFECTION;

ADULT; AGED; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MIDDLE AGED; MOUTH; NECK DISSECTION; OROPHARYNX; PHARYNX; RETROSPECTIVE STUDIES; RISK FACTORS; SURGICAL WOUND INFECTION;

EID: 84935067624     PISSN: 01945998     EISSN: 10976817     Source Type: Journal    
DOI: 10.1177/0194599815581808     Document Type: Article

References (47)

1. Tracy JC, Spiro JD,. Short hospital stay following neck dissection. Arch Otolaryngol Head Neck Surg. 2010; 136: 773-776.
2. Shellenberger TD, Madero-Visbal R, Weber RS,. Quality indicators in head and neck operations: a comparison with published benchmarks. Arch Otolaryngol Head Neck Surg. 2011; 137: 1086-1093.
3. Penel N, Fournier C, Lefebvre D, Lefebvre JL,. Multivariate analysis of risk factors for wound infection in head and neck squamous cell carcinoma surgery with opening of mucosa: study of 260 surgical procedures. Oral Oncol. 2005; 41: 294-303.
4. Munoz E, Goldstein J, Lory MH,. Hospital readmissions, otolaryngology, and the diagnosis related group hospital payment system. Arch Otolaryngol Head Neck Surg. 1990; 116: 708-713.
5. Davidson BJ, Newkirk KA, Harter KW,. Complications from planned, posttreatment neck dissections. Arch Otolaryngol Head Neck Surg. 1999; 125: 401-405.
6. Lauer MS, D'Agostino RB,. The randomized registry trial-the next disruptive technology in clinical research? N Engl J Med. 2013; 369: 1579-1581.
7. Chen MM, Roman SA, Sosa JA, Judson BL,. Postdischarge complications predict reoperation and mortality after otolaryngologic surgery. Otolaryngol Head Neck Surg. 2013; 149: 865-872.
8. Penel N, Lefebvre D, Fournier C,. Risk factors for wound infection in head and neck cancer surgery: a prospective study. Head Neck. 2011; 23: 447-455.
9. Lee DH, Kim SY, Nam SY,. Risk factors of surgical site infection in patients undergoing major oncological surgery for head and neck cancer. Oral Oncol. 2011; 47: 528-531.
10. Man LX, Beswick DM, Johnson JT,. Antibiotic prophylaxis in uncontaminated neck dissection. Laryngoscope. 2011; 121: 1473-1477.
11. Rowell KS, Turrentine FE, Hutter MM,. Use of national surgical quality improvement program data as a catalyst for quality improvement. J Am Coll Surg. 2007; 204: 1293-1300.
12. Birkmeyer JD, Shahian DM, Dimick JB,. Blueprint for a new American College of Surgeons: National Surgical Quality Improvement Program. J Am Coll Surg. 2008; 207: 777-782.
13. American College of Surgeons, National Surgical Quality Improvement Program. User Guide for the 2011 Participant Use Data File (2012). http://site.acsnsqip.org/wpcontent/uploads/2012/03/2011-User-GuideFinal.pdf. Accessed November 25, 2014.
14. Pellini R, Mercante G, Marchese C,. Predictive factors for postoperative wound complications after neck dissection. Acta Otorhinolaryngol Ital. 2013; 33: 16-22.
15. Righi M, Manfredi R, Farneti G,. Short-term versus long-term antimicrobial prophylaxis in oncologic head and neck surgery. Head Neck. 1996; 18: 399-404.
16. Nguyen KT, Gart MS, Smetona JT,. The relationship between relative value units and outcomes: a multivariate analysis of plastic surgery procedures. Eplasty. 2012; 12: e60.
17. Davenport DL, Henderson WG, Khuri SF,. Preoperative risk factors and surgical complexity are more predictive of costs than postoperative complications. Ann Surg. 2005; 242: 463-471.
18. Kim BD, Ver Halen JP, Grant DW, Kim JY,. Anesthesia duration as an independent risk factor for postoperative complications in free flap surgery: a review of 1,305 surgical cases. J Reconstr Microsurg. 2014; 30: 217-226.
19. Kim BD, Hsu WK, De Oliveira GSJ,. Operative duration as an independent risk factor for postoperative complications in single-level lumbar fusion: an analysis of 4588 surgical cases. Spine (Phila Pa 1976). 2014; 39: 510-520.
20. Boruk M, Chernobilsky B, Rosenfeld RM, Har-El G,. Age as a prognostic factor for complications of major head and neck surgery. Arch Otolaryngol Head Neck Surg. 2005; 131: 605-609.
21. Mlodinow AS, Khavanin N, Ver Halen JP,. Increased anesthesia duration increases venous thromboembolism risk in plastic surgery: a six-year analysis of over 19,000 cases. [published online 25, 2014 ]. J Hand Surg Plast Surg.
22. Khan MA, Grinberg R, Johnson S,. Perioperative risk factors for 30-day mortality after bariatric surgery: is functional status important? Surg Endosc. 2013; 27: 1772-1777.
23. Saha D, Davila AA, Ver Halen JP,. Post-mastectomy reconstruction: a risk-stratified comparative analysis of outcomes. Breast. 2013; 22: 1072-1080.
24. Makary MA, Segev DL, Pronovost PJ,. Frailty as a predictor of surgical outcomes in older patients. J Am Coll Surg. 2010; 210: 901-908.
25. Herranz J, Sarandeses A, Fernandex MF,. Complications after total laryngectomy in nonradiated laryngeal and hypopharyngeal carcinomas. Otolaryngol Head Neck Surg. 2000; 122: 892-898.
26. Zhu J, Fedewa S, Chen AY,. The impact of comorbidity on treatment (chemoradiation and laryngectomy) of advanced, nondistant metastatic laryngeal cancer: a review of 16 849 cases from the national cancer database (2003-2008). Arch Otolaryngol Head Neck Surg. 2012; 138: 1120-1128.
27. Derks W, de Leeuw RJ, Hordijk GJ,. Elderly patients with head and neck cancer: the influence of comorbidity on choice of therapy, complication rate, and survival. Curr Opin Otolaryngol Head Neck Surg. 2005; 13: 92-96.
28. Schwartz SR, Yuek B, Maynard C,. Predictors of wound complications after laryngectomy: a study of over 2000 patients. Otolaryngol Head Neck Surg. 2004; 131: 61-68.
29. Mucke T, Rau A, Weitz J,. Influence of irradiation and oncologic surgery on head and neck microsurgical reconstructions. Oral Oncol. 2012; 48: 367-371.
30. Penel N, Fournier C, Lefebvre D, Lefebvre JL,. Multivariate analysis of risk factors for wound infection in head and neck squamous cell carcinoma surgery with opening of mucosa: study of 260 surgical procedures. Oral Oncol. 2005; 41: 294-303.
31. Johnson JT, Kachman K, Wagner RL, Myers EN,. Comparison of ampicillin/sulbactam versus clindamycin in the prevention of infection in patients undergoing head and neck surgery. Head Neck. 1997; 19: 367-371.
32. Fabian TC, Croce MA, Payne LW,. Duration of antibiotic therapy for penetrating abdominal trauma: a prospective trial. Surgery. 1992; 112: 788-794.
33. Goldberg SR, Anand RJ, Como JJ,. Prophylactic antibiotic use in penetrating abdominal trauma: an Eastern Association for the Surgery of Trauma practice management guideline. J Trauma Acute Care Surg. 2012; 73: S321-S325.
34. Johnson JT, Myers EN, Thearle PB,. Antimicrobial prophylaxis for contaminated head and neck surgery. Laryngoscope. 1984; 94: 612-614.
35. Sepehr A, Santos BJ, Chou C,. Antibiotics in head and neck surgery in the setting of malnutrition, tracheotomy, and diabetes. Laryngoscope. 2009; 119: 549-553.
36. Semenov YR, Starmer HM, Gourin CG,. The effect of pneumonia on short-term outcomes and cost of care after head and neck cancer surgery. Laryngoscope. 2012; 122: 1994-2004.
37. Ma CY, Ji T, Ow A,. Surgical site infection in elderly oral cancer patients: is the evaluation of comorbid conditions helpful in the identification of high-risk ones? J Oral Maxillofac Surg. 2012; 70: 2445-2452.
38. Doerr TD, Marunick MT,. Timing of edentulation and extraction in the management of oral cavity and oropharyngeal malignancies. Head Neck. 1997; 19: 426-430.
39. Tomas I, Alvarez M, Limeres J,. Prevalence, duration and aetiology of bacteraemia following dental extractions. Oral Dis. 2007; 13: 56-62.
40. Benitez-Paez A.,. Detection of transient bacteraemia following dental extractions by 16S rDNA pyrosequencing: a pilot study. PLoS One. 2013; 8: e57782.
41. Soto-Barreras U, Olvera-Rubio JO, Loyola-Rodriguez JP,. Peripheral arterial disease associated with caries and periodontal disease. J Periodontol. 2013; 84: 486-494.
42. Sabatini PR, Ducic Y,. Planned neck dissection following primary chemoradiation for advanced-stage head and neck cancer. Otolaryngol Head Neck Surg. 2009; 141: 474-477.
43. Konofaos P, Hammond S, Ver Halen JP, Samant S,. Reconstructive techniques in transoral robotic surgery for head and neck cancer: a North American survey. Plast Reconstr Surg. 2013; 131: 188e-197e.
44. Eckel HE, Volling P, Pototschnig C,. Transoral laser resection with staged discontinuous neck dissection for oral cavity and oropharynx squamous cell carcinoma. Laryngoscope. 1995; 105: 53.
45. Samant S,. Sentinel node biopsy as an alternative to elective neck dissection for staging of early oral carcinoma. Head Neck. 2014; 36: 241-246.
46. Brennan S, Corry J, Kleid S,. Prospective trial to evaluate staged neck dissection or elective neck radiotherapy in patients with CT-staged T1-2 N0 squamous cell carcinoma of the oral tongue. Head Neck. 2010; 32: 191-198.
47. Shiloach M, Frencher SK Jr, Steeger JE,. Toward robust information: data quality and inter-rater reliability in the American College of Surgeons National Surgical Quality Improvement Program. J Am Coll Surg. 2010; 210: 6-16.