Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus

Cell

Volumn 174, Issue 3, 2018, Pages 744-757.e24

  Quinodoz, Sofia A ^a   Ollikainen, Noah ^a   Tabak, Barbara ^b   Palla, Ali ^a   Schmidt, Jan Marten ^a   Detmar, Elizabeth ^a   Lai, Mason M ^a   Shishkin, Alexander A ^a   Bhat, Prashant ^a,c   Takei, Yodai ^a   Trinh, Vickie ^a   Aznauryan, Erik ^a   Russell, Pamela ^d   Cheng, Christine ^e   Jovanovic, Marko ^f   Chow, Amy ^a   Cai, Long ^a   McDonel, Patrick ^b   Garber, Manuel ^b   Guttman, Mitchell ^a  

^a California Institute of Technology   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Global Health and Health Disparities   (United States)

^e Boston University   (United States)

^f Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

genome structure; higher order nuclear structure; multi way interactions; nuclear organization; nuclear speckle; Nuclear structure; nucleolus; RNA DNA interactions; SPRITE

Indexed keywords

GENOMIC DNA; RIBOSOME RNA; DNA;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CELL NUCLEUS INCLUSION BODY; CHROMOSOME ANALYSIS; CONTROLLED STUDY; DNA FLUORESCENCE IN SITU HYBRIDIZATION; EMBRYO; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE CLUSTER; GENE STRUCTURE; GENOME ANALYSIS; HUMAN; HUMAN CELL; INTERCHROMOSOMAL INTERACTION; LIMIT OF QUANTITATION; MALE; MEASUREMENT ACCURACY; MOUSE; NONHUMAN; NUCLEOLUS; PRIORITY JOURNAL; SPLIT POOL RECOGNITION OF INTERACTIONS BY TAG EXTENSION METHOD; CELL NUCLEUS; CHROMOSOMAL MAPPING; CHROMOSOME; EUKARYOTE; GENETICS; GENOME; PHYSIOLOGY; PROCEDURES; STRUCTURE ACTIVITY RELATION; ULTRASTRUCTURE;

CELL NUCLEOLUS; CELL NUCLEUS; CHROMOSOME MAPPING; CHROMOSOMES; DNA; EUKARYOTA; GENOME; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 85047950104     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2018.05.024     Document Type: Article

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