-
1
-
-
84957839638
-
CTLA-4 and PD-1 pathways: similarities, differences, and implications of their inhibition
-
Buchbinder EI, Desai A. CTLA-4 and PD-1 pathways: similarities, differences, and implications of their inhibition. Am J Clin Oncol (2016) 39(1):98-106. doi:10.1097/COC.0000000000000239
-
(2016)
Am J Clin Oncol
, vol.39
, Issue.1
, pp. 98-106
-
-
Buchbinder, E.I.1
Desai, A.2
-
2
-
-
84989918072
-
Safety and efficacy of durvalumab (MEDI4736), an anti-programmed cell death ligand-1 immune checkpoint inhibitor, in patients with advanced urothelial bladder cancer
-
Massard C, Gordon MS, Sharma S, Rafii S, Wainberg ZA, Luke J, et al. Safety and efficacy of durvalumab (MEDI4736), an anti-programmed cell death ligand-1 immune checkpoint inhibitor, in patients with advanced urothelial bladder cancer. J Clin Oncol (2016) 34(26):3119-25. doi:10.1200/JCO.2016.67.9761
-
(2016)
J Clin Oncol
, vol.34
, Issue.26
, pp. 3119-3125
-
-
Massard, C.1
Gordon, M.S.2
Sharma, S.3
Rafii, S.4
Wainberg, Z.A.5
Luke, J.6
-
3
-
-
84858800620
-
The immune contexture in human tumours: impact on clinical outcome
-
Fridman WH, Pagès F, Sautès-Fridman C, Galon J. The immune contexture in human tumours: impact on clinical outcome. Nat Rev Cancer (2012) 12(4):298-306. doi:10.1038/nrc3245
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.4
, pp. 298-306
-
-
Fridman, W.H.1
Pagès, F.2
Sautès-Fridman, C.3
Galon, J.4
-
4
-
-
84988600706
-
Immunoscore and Immunoprofiling in cancer: an update from the melanoma and immunotherapy bridge 2015
-
Galon J, Fox BA, Bifulco CB, Masucci G, Rau T, Botti G, et al. Immunoscore and Immunoprofiling in cancer: an update from the melanoma and immunotherapy bridge 2015. J Transl Med (2016) 14:273. doi:10.1186/s12967-016-1029-z
-
(2016)
J Transl Med
, vol.14
, pp. 273
-
-
Galon, J.1
Fox, B.A.2
Bifulco, C.B.3
Masucci, G.4
Rau, T.5
Botti, G.6
-
5
-
-
33749319703
-
Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
-
Galon J, Costes A, Sanchez-Cabo F, Kirilovsky A, Mlecnik B, Lagorce-Pagès C, et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science (2006) 313:1960-4. doi:10.1126/science.1129139
-
(2006)
Science
, vol.313
, pp. 1960-1964
-
-
Galon, J.1
Costes, A.2
Sanchez-Cabo, F.3
Kirilovsky, A.4
Mlecnik, B.5
Lagorce-Pagès, C.6
-
6
-
-
84920956732
-
PD-1 blockade induces responses by inhibiting adaptive immune resistance
-
Tumeh PC, Harview CL, Yearley JH, Shintaku IP, Taylor EJ, Robert L, et al. PD-1 blockade induces responses by inhibiting adaptive immune resistance. Nature (2014) 515(7528):568-71. doi:10.1038/nature13954
-
(2014)
Nature
, vol.515
, Issue.7528
, pp. 568-571
-
-
Tumeh, P.C.1
Harview, C.L.2
Yearley, J.H.3
Shintaku, I.P.4
Taylor, E.J.5
Robert, L.6
-
7
-
-
84964023141
-
High tumoral IFN? mRNA, PD-L1 protein, and combined IFN? mRNA/PD-L1 protein expression associates with response to durvalumab (anti-PD-L1) monotherapy in NSCLC patients
-
Higgs BW, Robbins PB, Blake-Haskins JA, Zhu W, Morehouse C, Brohawn PZ, et al. High tumoral IFN? mRNA, PD-L1 protein, and combined IFN? mRNA/PD-L1 protein expression associates with response to durvalumab (anti-PD-L1) monotherapy in NSCLC patients. Eur J Cancer (2015) 51(Suppl 3):S717, 15LBA. doi:10.1016/S0959-8049(16)31937-2
-
(2015)
Eur J Cancer
, vol.51
-
-
Higgs, B.W.1
Robbins, P.B.2
Blake-Haskins, J.A.3
Zhu, W.4
Morehouse, C.5
Brohawn, P.Z.6
-
8
-
-
85016106905
-
Rational selection of syngeneic preclinical tumor models for immunotherapeutic drug discovery
-
Mosely SI, Prime JE, Sainson RC, Koopmann JO, Wang DY, Greenawalt DM, et al. Rational selection of syngeneic preclinical tumor models for immunotherapeutic drug discovery. Cancer Immunol Res (2017) 5(1):29-41. doi:10.1158/2326-6066.CIR-16-0114
-
(2017)
Cancer Immunol Res
, vol.5
, Issue.1
, pp. 29-41
-
-
Mosely, S.I.1
Prime, J.E.2
Sainson, R.C.3
Koopmann, J.O.4
Wang, D.Y.5
Greenawalt, D.M.6
-
9
-
-
85047876789
-
Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment and holds potential for combination with immune checkpoint inhibitors. American Association for Cancer Research 110th Annual Meeting
-
Washington, DC (2017)
-
Mullins SR, Vogel K, Vasilako J, Grigsby I, Dovedi S, Ryan P, et al. Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment and holds potential for combination with immune checkpoint inhibitors. American Association for Cancer Research 110th Annual Meeting. Washington, DC (2017). Proc Am Assoc Cancer Res 2017: abst 4697
-
(2017)
Proc Am Assoc Cancer Res
-
-
Mullins, S.R.1
Vogel, K.2
Vasilako, J.3
Grigsby, I.4
Dovedi, S.5
Ryan, P.6
-
10
-
-
85047867218
-
Safety and pharmacodynamic activity of MEDI9197, a TLR 7/8 agonist, administered intratumorally in subjects with solid tumors. American Association for Cancer Research 110th Annual Meeting
-
Washington, DC (2017)
-
Gupta S, Grilley-Olson J, Hong D, Marabelle A, Munster P, Aggarwal R, et al. Safety and pharmacodynamic activity of MEDI9197, a TLR 7/8 agonist, administered intratumorally in subjects with solid tumors. American Association for Cancer Research 110th Annual Meeting. Washington, DC (2017). Proc Am Assoc Cancer Res 2017: abst CT091
-
Proc Am Assoc Cancer Res 2017
-
-
Gupta, S.1
Grilley-Olson, J.2
Hong, D.3
Marabelle, A.4
Munster, P.5
Aggarwal, R.6
-
11
-
-
84983751903
-
Targeting CD73 in the tumor microenvironment with MEDI9447
-
Hay CM, Sult E, Huang Q, Mulgrew K, Fuhrmann SR, McGlinchey KA, et al. Targeting CD73 in the tumor microenvironment with MEDI9447. Oncoimmunology (2016) 5(8):e1208875. doi:10.1080/2162402X.2016.1208875
-
(2016)
Oncoimmunology
, vol.5
, Issue.8
-
-
Hay, C.M.1
Sult, E.2
Huang, Q.3
Mulgrew, K.4
Fuhrmann, S.R.5
McGlinchey, K.A.6
-
12
-
-
84995569103
-
Co-inhibition of CD73 and A2AR adenosine signaling improves anti-tumor immune responses
-
Young A, Ngiow SF, Barkauskas DS, Sult E, Hay C, Blake SJ, et al. Co-inhibition of CD73 and A2AR adenosine signaling improves anti-tumor immune responses. Cancer Cell (2016) 30(3):391-403. doi:10.1016/j.ccell.2016.06.025
-
(2016)
Cancer Cell
, vol.30
, Issue.3
, pp. 391-403
-
-
Young, A.1
Ngiow, S.F.2
Barkauskas, D.S.3
Sult, E.4
Hay, C.5
Blake, S.J.6
-
13
-
-
0032555614
-
Prevention of allogeneic fetal rejection by tryptophan catabolism
-
Munn DH, Zhou M, Attwood JT, Bondarev I, Conway SJ, Marshall B, et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science (1998) 281:1191-3. doi:10.1126/science.281.5380.1191
-
(1998)
Science
, vol.281
, pp. 1191-1193
-
-
Munn, D.H.1
Zhou, M.2
Attwood, J.T.3
Bondarev, I.4
Conway, S.J.5
Marshall, B.6
-
14
-
-
84959292227
-
IDO in the tumor microenvironment: inflammation, counter-regulation, and tolerance
-
Munn DH, Mellor AL. IDO in the tumor microenvironment: inflammation, counter-regulation, and tolerance. Trends Immunol (2016) 37:193-207. doi:10.1016/j.it.2016.01.002
-
(2016)
Trends Immunol
, vol.37
, pp. 193-207
-
-
Munn, D.H.1
Mellor, A.L.2
|