Genetic predisposition, clinical risk factor burden, and lifetime risk of atrial fibrillation

Circulation

Volumn 137, Issue 10, 2018, Pages 1027-1038

  Weng, Lu Chen ^a,c   Preis, Sarah R ^d   Hulme, Olivia L ^a,c   Larson, Martin G ^d   Choi, Seung Hoan ^c   Wang, Biqi ^d   Trinquart, Ludovic ^d   McManus, David D ^e   Staerk, Laila ^d,f   Lin, Honghuang ^d,g   Lunetta, Kathryn L ^d   Ellinor, Patrick T ^a,b,c   Benjamin, Emelia J ^d,h   Lubitz, Steven A ^a,b,c  

^a Cardiovascular Research Center   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d BOSTON UNIVERSITY   (United States)

^e UNIVERSITY OF MASSACHUSETTS   (United States)

^f GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^g Herlev and Gentofte University Hospital ^*  (United States)

^h BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Atrial fibrillation; Epidemiology; Genetics; Lifetime risk; Polygenic risk; Risk factor; Risk stratification

Indexed keywords

ANTIHYPERTENSIVE AGENT;

ADULT; AGE; ARTICLE; ATRIAL FIBRILLATION; BODY HEIGHT; BODY WEIGHT; CARDIOVASCULAR RISK; COHORT ANALYSIS; DIABETES MELLITUS; DIASTOLIC BLOOD PRESSURE; DRUG USE; FEMALE; FOLLOW UP; GENETIC PREDISPOSITION; HEART FAILURE; HEART INFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; SYSTOLIC BLOOD PRESSURE; GENETICS; HYPERTENSION; LONGITUDINAL STUDY; MIDDLE AGED; PARTICIPATORY RESEARCH; RISK FACTOR; UNITED STATES;

ADULT; ANTIHYPERTENSIVE AGENTS; ATRIAL FIBRILLATION; COHORT STUDIES; COMMUNITY-BASED PARTICIPATORY RESEARCH; FEMALE; FOLLOW-UP STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERTENSION; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; UNITED STATES;

EID: 85047761129     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.117.031431     Document Type: Article

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