Phosphorothioate oligonucleotides, suramin and heparin inhibit DNA-dependent protein kinase activity

British Journal of Cancer

Volumn 86, Issue 7, 2002, Pages 1143-1149

  Hosoi, Y ^a,b   Matsumoto, Y ^a   Tomita, M ^a   Enomoto, A ^a   Morita, A ^a   Sakai, K ^c   Umeda, N ^a   Zhao, H J ^b   Nakagawa, K ^a   Ono, T ^b   Suzuki, N ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c CENTRAL RESEARCH INSTITUTE OF ELECTRIC POWER INDUSTRY   (Japan)

Author keywords

DNA double stranded breaks; DNA PK; Phosphorothioate oligonucleotides; Radiation sensitivity; Suramin

Indexed keywords

DNA DEPENDENT PROTEIN KINASE; DOUBLE STRANDED DNA; HEPARIN; OLIGONUCLEOTIDE; OLIGONUCLEOTIDE PHOSPHOROTHIOATE; SURAMIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DNA STRAND BREAKAGE; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL; RADIOSENSITIVITY;

ANTINEOPLASTIC AGENTS; CELL CULTURE TECHNIQUES; DNA DAMAGE; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; FIBRINOLYTIC AGENTS; FIBROBLASTS; GLIOBLASTOMA; HEPARIN; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; NUCLEAR PROTEINS; OLIGONUCLEOTIDES; PROTEIN-SERINE-THREONINE KINASES; RADIATION-SENSITIZING AGENTS; SURAMIN; THIONUCLEOTIDES; TUMOR CELLS, CULTURED;

EID: 85047696478     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600191     Document Type: Article

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