Functional characterization of a small conductance GIRK channel in rat atrial cells

Biophysical Journal

Volumn 87, Issue 5, 2004, Pages 3122-3136

  Nikolov, Emil N ^a   Ivanova Nikolova, Tatyana T ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; ION CHANNEL; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONDUCTANCE; CONTROLLED STUDY; ELECTRIC CONDUCTIVITY; HEART ATRIUM; HEART MUSCLE CELL; NONHUMAN; RAT; SYNAPTIC TRANSMISSION; ANIMAL; CELL CULTURE; CELL MEMBRANE POTENTIAL; HEART ATRIUM FUNCTION; MUSCLE CELL; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ATRIAL FUNCTION; CELLS, CULTURED; ELECTRIC CONDUCTIVITY; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; ION CHANNEL GATING; MEMBRANE POTENTIALS; MUSCLE CELLS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RATS; RATS, SPRAGUE-DAWLEY;

EID: 85047692586     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.103.039487     Document Type: Article

References (39)

1. KACh. J. Biol. Chem. 277:48282-48288.
2. Colquhoun, D., and A. G. Hawkes. 1981. On the stochastic properties of single ion channels. Proc. R. Soc. B. 211:205-235.
3. Colquhoun, D., and A. G. Hawkes. 1983. The principles of the stochastic interpretation of ion-channel mechanisms. In Single Channel Recording. B. Sakmann, and E. Neher, editors. Plenum Press, New York. 135-175.
4. Colquhoun, D., and B. Sakmann. 1985. Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate. J. Physiol. 369:501-557.
5. + (GIRK4) channel homomultimers. J. Biol. Chem. 273:27499-27504.
6. + channels (GIRKs). J. Biol. Chem. 276:11409-11413.
7. + channels. Cell. Signal. 9:551-573.
8. + channel: expression cloning and molecular properties. Proc. Natl. Acad. Sci. USA. 90:10235-10239.
9. + channels. Proc. Natl. Acad. Sci. USA. 94:10461-10466.
10. + conduction and selectivity. Science. 280:69-77.
11. Foster, K. A., P. J. McDermott, and J. D. Robishaw. 1990. Expression of G proteins in rat cardiac myocytes: Effect of KCl depolarization. Am. J. Physiol. 28:H432-H441.
12. Hamill, O. P., A. Many, E. Neher, B. Sakmann, and F. J. Sigworth. 1981. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 391:85-100.
13. + channel activity through interactions with the βγ subunits of G proteins. J. Biol. Chem. 277:6088-6096.
14. + channel in atrial myocytes of guinea pig heart. J. Gen. Physiol. 98:517-533.
15. + channel in the heart: Modal regulation by G protein βγ subunits. J. Gen. Physiol. 112:199-210.
16. Jiang, Y., A. Lee, J. Chen, M. Cadene, B. T. Chait, and R. MacKinnon. 2002. The open pore conformation of potassium channels. Nature. 417:523-526.
17. + channel by pivoted bending of a transmembrane segment. 2002. Mol. Cell. 10:469-481.
18. Kozasa, T., and A. G. Gilman. 1995. Purification of recombinant G proteins from Sf9 cells by hexahistidine tagging of associated subunits. J. Biol. Chem. 270:1734-1741.
19. + channel via cyclic AMP-dependent protein kinase in atrial cells. Circ. Res. 67:1292-1298.
20. + channel proteins. Nature. 374:135-141.
21. KATP. J. Biol. Chem. 270:28777-28779.
22. Kubo, Y., E. Reuveny, P. A. Slesinger, Y. N. Jan, and L. Y. Jan. 1993. Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel. Nature. 364:802-806.
23. + channels. J. Biol. Chem. 275:921-929.
24. + current in adult mouse atria. Br. J. Pharmacol. 140:576-584.
25. Mullner, C., D. Yakubovich, C. W. Dessauer, D. Platzer, and W. Schreibmayer. 2003. Single channel analysis of the regulation of GIRK1/GIRK4 channels by protein phosphorylation. Biophys. J. 84:1399-1409.
26. Nikolov, E. N., and T. I. Ivanova-Nikolova. 2004. Coordination of membrane excitability through a GIRK1 signaling complex in the atria. J. Biol. Chem. 279:23630-23636.
27. Nishida, M., and R. MacKinnon. 2002. Structural basis of inward rectification: Cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 A resolution. Cell. 111:957-965.
28. + channel, GIRK. Neuron. 33:87-99.
29. Sadja, R., N. Alagem, and E. Reuveny. 2003. Gating of GIRK channels: Details of an intricate, membrane-delimited signaling complex. Neuron. 39:9-12.
30. + currents. Nature. 390:525-529.
31. + channel. J. Biol. Chem. 266:19528-19535.
32. + channel by a G-protein-independent mechanism. J. Gen. Physiol. 108:381-391.
33. + channel: subunit stoichiometry and structural domains essential for G protein stimulation. Am. J. Physiol. 271:H379-H385.
34. Wickman, K. D., J. A. Inigues-Lluhi, P. A. Davenport, R. Taussing, G. B. Krapivinsky, M. E. Linder, A. G. Gilman, and D. E. Clapham. 1994. Recombinant G-protein βγ subunits activate the muscarinic-gated atrial potassium channel. Nature. 368:255-257.
35. Wickman, K., J. Nemec, S. J. Gendler, and D. E. Clapham. 1998. Abnormal heart rate regulation in GIRK4 knockout mice. Neuron. 20:103-114.
36. + channels expressed in Xenopus oocytes. J. Physiol. 524:737-755.
37. + channels in the negative chronotropic effect of a muscarinic agonist. J. Pharmacol. Exp. Ther. 300:681-687.
38. Yamada, M., A. Inanobe, and Y. Kurachi. 1998. G protein regulation of potassium ion channels. Pharmacol. Rev. 50:723-757.
39. Yi, B. A., Y. F. Lin, Y. N. Jan, and L. Y. Jan. 2001. Yeast screen for constitutively active mutant G protein-activated potassium channels. Neuron. 29:657-667.