Furosemide inhibits 11β-hydroxysteroid dehydrogenase type 2

Endocrinology

Volumn 139, Issue 9, 1998, Pages 3849-3854

  Fuster, Daniel ^a   Escher, Geneviève ^a   Vogt, Bruno ^a   Ackermann, Daniel ^a   Dick, Bernhard ^a   Frey, Brigitte M ^a   Frey, Felix J ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; FUROSEMIDE; HYDROCORTISONE; MINERALOCORTICOID; MINERALOCORTICOID RECEPTOR; TETRAHYDROCORTISOL; DIURETIC AGENT; ENZYME INHIBITOR; HYDROXYSTEROID DEHYDROGENASE; TETRAHYDROCORTISONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENZYME INHIBITION; INHIBITION KINETICS; KIDNEY DISTAL TUBULE; MALE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; ANIMAL; CELL STRAIN COS1; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HUMAN; IN VITRO STUDY; KIDNEY TUBULE; URINE; WISTAR RAT;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; COS CELLS; DIURETICS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FUROSEMIDE; HUMANS; HYDROXYSTEROID DEHYDROGENASES; KIDNEY TUBULES; MALE; RATS; RATS, WISTAR; TETRAHYDROCORTISONE;

EID: 85047678329     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.9.6175     Document Type: Article

References (45)

1. White PC, Mune T, Agarwal AK 1997 11β-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess. Endocr Rev 18:135-156
2. Funder JW, Pearce PT, Smith R, Smith AI 1988 Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science 243:583-585
3. Frey FJ 1987 Kinetics and dynamics of prednisolone. Endocr Rev 8:453-473
4. Escher G, Frey FJ, Frey BM 1994 11β-Hydroxysteroid dehydrogenase accounts tor low prednisolone/prednisone ratios in the kidney. Endocrinology 135:101-106
5. Agarwal AK, Monder C, Eckstein B, White PC 1989 Cloning and expression of rat cDNA encoding corticosteroid 11β-hydroxysteroid dehydrogenase. J Biol Chem 264:18939-18943
6. Albiston AL, Obeyesekere VR, Smith RE, Krozowski Z 1994 Cloning and tissue distribution of the human 11β-hydroxysteroid dehydrogenase type 2 enzyme. Mol Cell Endocrinol 105:R11-R15
7. Monder C, Lakshmi V 1990 Corticosteroid 11β-dehydrogenase of rat tissues: immunological studies. Endocrinology 126:2435-2443
8. Rundle C, Funder J, Lakshmi V, Monder C 1989 The intrarenal localization of mineralocorticoid receptors and 11β-dehydrogenase: immunocytochemical studies. Endocrinology 125:1700-1704
9. Monder C, Miroff Y, Marandici A, Hardy MP 1994 11β-Hydroxysteroid dehydrogenase alleviates glucocorticoid-mediated inhibition of steroidgenesis in rat Leydig cells. Endocrinology 134:1199-1204
10. Stewart PM, Whorwood CB 1994 11β-Hydroxysteroid dehydrogenase activity and corticosteroid hormone action. Steroids 59:90-95
11. Escher G, Galli I, Vishwanath BS, Frey BM, Frey FJ 1997 TNFα and IL-1β enhance the cortisone/cortisol shuttle. J Exp Med 186:189-198
12. Stewart PM, Krozowski ZS, Gupta A, Milford DV, Howie AJ, Sheppard MC, Whorwood CB 1996 Human hypertension in the syndrome of apparent mineralocorticoid excess due to mutation of the 11β-hydroxysteroid dehydrogenase type 2 gene. Lancet 1:88-91
13. Ferrari P, Obeyesekere VR, Li K, Wilson RC, New MI, Funder JW, Krozowski ZS 1996 Point mutations abolish 11β-hydroxysteroid dehydrogenase type II activity in three families with the congenital syndrome of apparent mineralocorticoid excess. Mol Cell Endocrinol 119:21-24
14. Smith RE, Li KXZ, Andrews RK, Krozowski ZS 1997 Immunohistochemical and molecular characterization of the rat 11β-hydroxysteroid dehydrogenase type II enzyme. Endocrinology 138:540-547
15. Lo YH, Sheff MF, Latif SA, Ribeiro C, Silver H, Brem AS, Morris DJ 1997 Kidney 11β-HSD2 is inhibited by glycyrrhetinic acid-like factors in human urine. Hypertension 29:500-505
16. Escher G, Nawrocki A, Staub T, Vishwanath BS, Frey BM, Reichen J, Frey FJ 1998 Down-regulation of hepatic and renal 11β-hydroxysteroid dehydrogenase in rats with liver cirrhosis. Gastroenterology 114:175-184
17. Souness GW, Morris DJ 1989 The antinatriuretic and kaliuretic effects of corticosterone and cortisol following pretreatment with carbenoxolone sodium (a liquorice derivative) in the adrenalectomized rat. Endocrinology 124:1588-1590
18. Souness GW, Morris DJ 1996 11α-and 11β-hydroxyprogesterone, potent inhibitors of 11β-hydroxysteroid dehydrogenase, possess hypertensinogenic activity in the rat. Hypertension 27:421-425
19. Song D, Lorenzo B, Reidenberg MM 1992 Inhibition of 11β-hydroxysteroid dehydrogenase by gossypol and bioflavonoids. J Lab Clin Med 120:792-797
20. Bühler H, Perschel FH, Hierholzer K 1991 Inhibition of rat 11β-hydroxysteroid dehydrogenase by steroidal compounds and triterpenoids, structure function relationship. Biochim Biophys Acta 1075:206-212
21. Zhang YD, Lorenzo B, Reidenberg MM 1994 Inhibition of 11β-hydroxysteroid dehydrogenase obtained from guinea pig kidney by furosemide, naringenin and some other compounds. J Steroid Biochem Mol Biol 49:81-85
22. Escher G, Meyer KV, Vishwanath BS, Frey BM, Frey FJ 1995 Furosemide inhibits 11β-hydroxysteroid dehydrogenase in vitro and in vivo. Endocrinology 136:1759-1765
23. Escher G, Vogt B, Beck T, Guntern D, Frey BM, Frey FJ 1998 Reduced 11β-hydroxysteroid dehydrogenase activity in the remaining kidney following nephrectomy. Endocrinology 139:1533-1539
24. Monder C, Lakshmi V, Miroff Y 1991 Kinetic studies on rat liver 11β-hydroxysteroid dehydrogenase. Biochim Biophys Acta 1115:23-29
25. Doucet A, Katz AI, Morel F 1979 Determination of Na-K-ATPase activity in single segments of the mammalian nephron. Am J Physiol 237:F105-R113
26. Alfaidy N, Blot-Chabaud M, Robic D, Kenouch S, Bourbouze R, Bonvalet JP, Farman N 1995 Characteristics and regulation of 11β-hydroxysteroid dehydrogenase of proximal and distal nephron. Biochim Biophys Acta 1243:461-468
27. Féraille E, Vogt B, Rousselot M, Barlet-Bas C, Cheval L, Doucet A, Favre H 1993 Mechanism of enhanced Na-K-ATPase activity in cortical collecting duct from rats with nephrotic syndrome. J Clin Invest 91:1295-1300
28. Phillips HJ 1973 Dye exclusion tests for cell viability. In: Kruse Jr PF, Patterson Jr MK (eds) Tissue Culture: Methods and Applications. Academic Press, London, p 406
29. Shackleton CHL 1993 Mass spectrometry in the diagnosis of steroid-related disorders and in hypertension research. J Steroid Biochem Mol Biol 45:127-140
30. Shackleton CHL 1986 Profiling steroid hormones and urinary steroids. J Chromatogr 379:91-156
31. Bicíková M, Hill M, Hampl R, Stárka L 1996 Inhibition of rat renal and testicular 11β-hydroxysteroid dehydrogenase by some antihypertensive drugs, diuretics, and epitestosterone. Horm Metab Res 29:465-468
32. Monder C, Stewart FM, Lakshmi V, Valentino R, Burt D, Edwards CRW 1989 Licorice inhibits corticosteroid 11-dehydrogenase of rat kidney and liver: in vivo and in vitro studies. Endocrinology 125:1046-1053
33. Bujalska I, Shimojo M, Howie A, Stewart PM 1997 Human 11β-hydroxysteroid dehydrogenase: studies on the stably transfected isoforms and localization of the type 2 isoenzyme within renal tissue. Steroids 62:77-82
34. Greger R 1985 Ion transport mechanisms in thick ascending limb of Henle's loop of mammalian nephron. Physiol Rev 65:760-797
35. + transport studied by microperfusion of the rat nephron. Am J Physiol 218:292-297
36. Mühlberg W, Platt D, Neubig E 1986 Pharmacokinetics and pharmacodynamics of furosemide in geriatric patients. Arch Gerontol Geriatr 5:249-263
37. Reeuwijk HJEM, Tjaden UR, van der Greef J 1992 Simultaneous determination of furosemide and amiloride in plasma using high-performance liquid chromatography with fluorescence detection. J Chromatogr 575:269-274
38. Brater DC, Chennavasin P, Day B, Burdette A, Anderson S 1983 Bumetamide and furosemide. Clin Pharmacol Ther 34:207-213
39. Bichet DG, Anderson RJ, Schrier RW 1992 Renal sodium excretion, edematous disorders, and diuretic use. In: Schrier RW (ed) Renal and Electrolyte Disorders. Little, Brown, Boston, Toronto, and London, pp 89-159
40. Prichard BNC, Owens CWI, Woolf AS 1992 Adverse reactions to diuretics. Eur Heart J [Suppl G] 13:96-103
41. Ulick S, Levine LS, Gunczler P, Zanconato G, Ramirez LC, Rauh W, Rösler A, Bradlow HL, New MI 1979 A syndrom of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of cortisol. J Clin Endocrinol Metab 49:757-764
42. Stewart PM, Valentino R, Wallace AM, Burt D, Shackleton CHL, Edwards CRW 1987 Mineralocorticoid activity of liquorice: 11β-hydroxysteroid dehydrogenase deficiency comes of age. Lancet 11:821-824
43. Van Buren M, Rabelink TJ, Koppeschaar HPF, Koomans HA 1993 Role of glucocorticoid in excretion of an acute potassium load in patients with Addison's disease and panhypopituitarism. Kidney Int 44:1130-1138
44. Weinberger MH 1992 Mechanisms of diuretic effects on carbohydrate tolerance, insulin sensitivity and lipid levels. Eur Heart J [Suppl G]13:5-9
45. Lindheimer MD, Katz AI 1991 The kidney, hypertension in pregnancy. In: Brenner BM, Rector Jr FC (eds) The Kidney. Saunders, Philadelphia, vol 2:1551-1656