Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of α-dystroglycan

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 33, 2016, Pages 9280-9285

  Kuwabara, Naoyuki ^a   Manya, Hiroshi ^b   Yamada, Takeyuki ^b   Tateno, Hiroaki ^c   Kanagawa, Motoi ^d   Kobayashi, Kazuhiro ^d   Akasaka Manya, Keiko ^b   Hirose, Yuriko ^e   Mizuno, Mamoru ^e   Ikeguchi, Mitsunori ^f   Toda, Tatsushi ^d   Hirabayashi, Jun ^c   Senda, Toshiya ^a,g   Endo, Tamao ^b   Kato, Ryuichi ^a,g  

^a INSTITUTE OF MATERIALS STRUCTURE SCIENCE   (Japan)

^b Tokyo Metropolitan Institute of Gerontology   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^d KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e NOGUCHI INSTITUTE   (Japan)

^f YOKOHAMA CITY UNIVERSITY   (Japan)

^g GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

Author keywords

Glycosyltransferase; Lectin; Muscular dystrophy; O mannosyl glycan; Dystroglycanopathy

Indexed keywords

ALPHA DYSTROGLYCAN; CARBOHYDRATE; FUKUTIN; GLYCAN; GLYCOSYLTRANSFERASE; POMGNT1 GLYCOSYLTRANSFERASE; UNCLASSIFIED DRUG; DAG1 PROTEIN, HUMAN; DYSTROGLYCAN; MANNOSE; N ACETYLGLUCOSAMINYLTRANSFERASE; PROTEIN O-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE;

ARTICLE; CATALYST; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISULFIDE BOND; ENZYME ACTIVE SITE; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; MUSCLE EYE BRAIN DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; SURFACE PLASMON RESONANCE; BINDING SITE; CHEMISTRY; CRYSTALLIZATION; GLYCOSYLATION;

BINDING SITES; CRYSTALLIZATION; DYSTROGLYCANS; GLYCOSYLATION; HUMANS; MANNOSE; N-ACETYLGLUCOSAMINYLTRANSFERASES;

EID: 85047290208     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1525545113     Document Type: Article

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