Vitamin C Pharmacokinetics in Critically Ill Patients: A Randomized Trial of Four IV Regimens

Chest

Volumn 153, Issue 6, 2018, Pages 1368-1377

  de Grooth, Harm Jan ^a   Manubulu Choo, Wai Ping ^a,b   Zandvliet, Anthe S ^a   Spoelstra de Man, Angélique M E ^a   Girbes, Armand R ^a   Swart, Eleonora L ^a   Oudemans van Straaten, Heleen M ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Department of Pharmacy ^*  (Netherlands)

Author keywords

ascorbate; ascorbic acid; clinical trial; intensive care; pharmacology

Indexed keywords

ASCORBIC ACID; OXALIC ACID; BIOLOGICAL MARKER; VITAMIN;

ADULT; AGED; ARTICLE; ASCORBIC ACID DEFICIENCY; CLINICAL ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; CREATININE CLEARANCE; CRITICAL ILLNESS; DRUG BLOOD LEVEL; DRUG EXCRETION; DRUG SAFETY; FEMALE; HUMAN; MALE; MULTIPLE ORGAN FAILURE; NETHERLANDS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REFERENCE VALUE; STEADY STATE; VOLUME OF DISTRIBUTION; BLOOD; DOSE RESPONSE; FOLLOW UP; INTRAVENOUS DRUG ADMINISTRATION; MIDDLE AGED; RETROSPECTIVE STUDY;

AGED; ASCORBIC ACID; BIOMARKERS; CRITICAL ILLNESS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; MULTIPLE ORGAN FAILURE; RETROSPECTIVE STUDIES; VITAMINS;

EID: 85047272882     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1016/j.chest.2018.02.025     Document Type: Article

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