Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Barbeira, Alvaro N ^a   Dickinson, Scott P ^a   Bonazzola, Rodrigo ^a   Zheng, Jiamao ^a   Wheeler, Heather E ^b   Torres, Jason M ^a   Torstenson, Eric S ^c   Shah, Kaanan P ^a   Garcia, Tzintzuni ^a   Edwards, Todd L ^c   Stahl, Eli A ^d   Huckins, Laura M ^d   Aguet, François ^e   Ardlie, Kristin G ^e   Cummings, Beryl B ^e,f   Gelfand, Ellen T ^e   Getz, Gad ^e,g   Hadley, Kane ^e   Handsaker, Robert E ^e,h   Huang, Katherine H ^e   Kashin, Seva ^e,h   Karczewski, Konrad J ^e,f   Lek, Monkol ^e,f   Li, Xiao ^e,i   MacArthur, Daniel G ^e,f   Nedzel, Jared L ^e   Nguyen, Duyen T ^e   Noble, Michael S ^e   Segrè, Ayellet V ^e   Trowbridge, Casandra A ^e   Tukiainen, Taru ^e,f   Abell, Nathan S ^i,j   Balliu, Brunilda ^j   Barshir, Ruth ^k   Basha, Omer ^k   Battle, Alexis ^l   Bogu, Gireesh K ^m,n   Brown, Andrew ^o,p,q   Brown, Christopher D ^r   Castel, Stephane E ^s,t   Chen, Lin S ^a   Chiang, Colby ^u   Conrad, Donald F ^u   Damani, Farhan N ^l   Davis, Joe R ^i,j   Delaneau, Olivier ^o,p,q   Dermitzakis, Emmanouil T ^o,p,q   Engelhardt, Barbara E ^v   Eskin, Eleazar ^w,x   Ferreira, Pedro G ^y,z   Frésard, Laure ^i,j   Gamazon, Eric R ^c,aa   Garrido Martín, Diego ^m,n   Gewirtz, Ariel D H ^ab   Gliner, Genna ^v   Gloudemans, Michael J ^i,j   Guigo, Roderic ^m,n,ac   Hall, Ira M ^u   Han, Buhm ^ad   He, Yuan ^ae   Hormozdiari, Farhad ^w   Howald, Cedric ^o,p,q   Jo, Brian ^ab   Kang, Eun Yong ^w   Kim, Yungil ^l   Kim Hellmuth, Sarah ^s,t   Lappalainen, Tuuli ^s,t   Li, Gen ^af   Li, Xin ^j   Liu, Boxiang ^i,j   Mangul, Serghei ^w   McCarthy, Mark I ^ag,ah,ai   McDowell, Ian C ^aj   Mohammadi, Pejman ^s,t   Monlong, Jean ^m,n,ak   Montgomery, Stephen B ^i,j   Muñoz Aguirre, Manuel ^m,n,al   Ndungu, Anne W ^ag   Nobel, Andrew B ^am,an   Oliva, Meritxell ^a,ao   Ongen, Halit ^o,p,q   Palowitch, John J ^am   Panousis, Nikolaos ^o,p,q   Papasaikas, Panagiotis ^m,n   Park, YoSon ^r   Parsana, Princy ^l   Payne, Anthony J ^ag   Peterson, Christine B ^ap   Quan, Jie ^aq   Reverter, Ferran ^m,n,ar   Sabatti, Chiara ⁱ   Saha, Ashis ^l   Sammeth, Michael ^as   Scott, Alexandra J ^u   Shabalin, Andrey A ^at   Sodaei, Reza ^m,n   Stephens, Matthew ^a   Stranger, Barbara E ^a,ao   Strober, Benjamin J ^ae   Sul, Jae Hoon ^au   Tsang, Emily K ^i,j   Urbut, Sarah ^a   Van De Bunt, Martijn ^ag,ah   Wang, Gao ^a   Wen, Xiaoquan ^av   Wright, Fred A ^aw   Xi, Hualin S ^aq   Yeger Lotem, Esti ^k   Zappala, Zachary ^i,j   Zaugg, Judith B ^ax   Zhou, Yi Hui ^aw   Akey, Joshua M ^ab   Bates, Daniel ^ay   Chan, Joanne ⁱ   Claussnitzer, Melina ^e,h,az   Demanelis, Kathryn ^a   Diegel, Morgan ^ay   Doherty, Jennifer A ^ba   Feinberg, Andrew P ^ae,bb,bc   Fernando, Marian S ^a,ao   Halow, Jessica ^ay   Hansen, Kasper D ^bb,bd   Haugen, Eric ^ay   Hickey, Peter F ^bd   Hou, Lei ^e,be   Jasmine, Farzana ^a   Jian, Ruiqi ⁱ   Jiang, Lihua ⁱ   Johnson, Audra ^ay   Kaul, Rajinder ^ay   Kellis, Manolis ^e,be   Kibriya, Muhammad G ^a   Lee, Kristen ^ay   Li, Jin Billy ⁱ   Li, Qin ⁱ   Lin, Jessica ^i,bf   Lin, Shin ^i,bg   Linder, Sandra ^i,j   Linke, Caroline ^a,ao   Liu, Yaping ^e,be   Maurano, Matthew T ^bh   Molinie, Benoit ^e   Nelson, Jemma ^ay   Neri, Fidencio J ^ay   Park, Yongjin ^e,be   Pierce, Brandon L ^a   Rinaldi, Nicola J ^e,be   Rizzardi, Lindsay F ^bb   Sandstrom, Richard ^ay   Skol, Andrew ^a,ao   Smith, Kevin S ^i,j   Snyder, Michael P ⁱ   Stamatoyannopoulos, John ^ay,bf   Tang, Hua ⁱ   Wang, Li ^e   Wang, Meng ⁱ   Van Wittenberghe, Nicholas ^e   Wu, Fan ^a,ao   Zhang, Rui ⁱ   Nierras, Concepcion R ^bi   Branton, Philip A ^bj   Carithers, Latarsha J ^bj,bk   Guan, Ping ^bj   Moore, Helen M ^bj   Rao, Abhi ^bj   Vaught, Jimmie B ^bj   Gould, Sarah E ^bl   Lockart, Nicole C ^bl   Martin, Casey ^bl   Struewing, Jeffery P ^bl   Volpi, Simona ^bl   Addington, Anjene M ^bm   Koester, Susan E ^bm   Little, A Roger ^bn   Brigham, Lori E ^bo   Hasz, Richard ^bp   Hunter, Marcus ^bq   Johns, Christopher ^br   Johnson, Mark ^bs   Kopen, Gene ^bt   Leinweber, William F ^bt   Lonsdale, John T ^bt   McDonald, Alisa ^bt   Mestichelli, Bernadette ^bt   Myer, Kevin ^bq   Roe, Brian ^bq   Salvatore, Michael ^bt   Shad, Saboor ^bt   Thomas, Jeffrey A ^bt   Walters, Gary ^bs   Washington, Michael ^bs   Wheeler, Joseph ^br   Bridge, Jason ^bu   Foster, Barbara A ^bv   Gillard, Bryan M ^bv   Karasik, Ellen ^bv   Kumar, Rachna ^bv   Miklos, Mark ^bu   Moser, Michael T ^bv   Jewell, Scott D ^bw   Montroy, Robert G ^bw   Rohrer, Daniel C ^bw   Valley, Dana R ^bw   Davis, David A ^bx   Mash, Deborah C ^bx   Undale, Anita H ^by   Smith, Anna M ^bz   Tabor, David E ^bz   Roche, Nancy V ^bz   McLean, Jeffrey A ^bz   Vatanian, Negin ^bz   Robinson, Karna L ^bz   Sobin, Leslie ^bz   Barcus, Mary E ^bz   Valentino, Kimberly M ^bz   Qi, Liqun ^bz   Hunter, Steven ^bz   Hariharan, Pushpa ^bz   Singh, Shilpi ^bz   Um, Ki Sung ^bz   Matose, Takunda ^bz   Tomaszewski, Maria M ^bz   Barker, Laura K ^ca   Mosavel, Maghboeba ^cb   Siminoff, Laura A ^ca   Traino, Heather M ^ca   Flicek, Paul ^cc   Juettemann, Thomas ^cc   Ruffier, Magali ^cc   Sheppard, Dan ^cc   Taylor, Kieron ^cc   Trevanion, Stephen J ^cc   Zerbino, Daniel R ^cc   Craft, Brian ^cd   Goldman, Mary ^cd   Haeussler, Maximilian ^cd   Kent, W James ^cd   Lee, Christopher M ^cd   Paten, Benedict ^cd   Rosenbloom, Kate R ^cd   Vivian, John ^cd   Zhu, Jingchun ^cd   Nicolae, Dan L ^a   Cox, Nancy J ^c   Im, Hae Kyung ^a   more..

^a UNIVERSITY OF CHICAGO   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^f MASSACHUSETTS GENERAL HOSPITAL   (United States)

^g MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^h HARVARD MEDICAL SCHOOL   (United States)

ⁱ STANFORD UNIVERSITY   (United States)

^j STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^k BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^l Whiting School of Engineering   (United States)

^m BARCELONA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Spain)

ⁿ UNIVERSITAT POMPEU FABRA   (Spain)

^o UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^p UNIVERSITY OF GENEVA   (Switzerland)

^q SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^r UNIVERSITY OF PENNSYLVANIA   (United States)

^s NEW YORK GENOME CENTER   (United States)

^t New York Presbyterian Morgan Stanley Children's Hospital   (United States)

^u WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^v Princeton University   (United States)

^w Department of Civil and Environmental Engineering   (United States)

^x UNIVERSITY OF CALIFORNIA   (United States)

^y UNIVERSITY OF PORTO   (Portugal)

^z UNIVERSITY OF PORTO   (Portugal)

^aa UNIVERSITY OF AMSTERDAM   (Netherlands)

^ab PRINCETON UNIVERSITY   (United States)

^ac HOSPITAL DEL MAR   (Spain)

^ad University of Ulsan College of Medicine   (South Korea)

^ae Johns Hopkins University School of Medicine   (United States)

^af Mailman School of Public Health   (United States)

^ag UNIVERSITY OF OXFORD   (United Kingdom)

^ah UNIVERSITY OF OXFORD   (United Kingdom)

^ai CHURCHILL HOSPITAL   (United Kingdom)

^aj DUKE UNIVERSITY   (United States)

^ak MCGILL UNIVERSITY   (Canada)

^al UNIVERSITAT POLITÈCNICA DE CATALUNYA   (Spain)

^am University of North Carolina at Chapel Hill   (United States)

^an The University of North Carolina at Chapel Hill   (United States)

^ao UNIVERSITY OF CHICAGO   (United States)

^ap UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^aq PFIZER INC   (United States)

^ar UNIVERSITY OF BARCELONA   (Spain)

^as FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^at UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^au UNIVERSITY OF CALIFORNIA   (United States)

^av UNIVERSITY OF MICHIGAN   (United States)

^aw NORTH CAROLINA STATE UNIVERSITY   (United States)

^ax EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^ay Altius Institute for Biomedical Sciences   (United States)

^az UNIVERSITY OF HOHENHEIM   (Germany)

^ba UNIVERSITY OF UTAH   (United States)

^bb JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^bc JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^bd JOHNS HOPKINS UNIVERSITY   (United States)

^be MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^bf UNIVERSITY OF WASHINGTON   (United States)

^bg UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^bh NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^bi NATIONAL INSTITUTES OF HEALTH   (United States)

^bj NATIONAL CANCER INSTITUTE   (United States)

^bk NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^bl NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^bm NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^bn NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^bo Washington Regional Transplant Community   (United States)

^bp Gift of Life Donor Program   (United States)

^bq LifeGift   (United States)

^br Center for Organ Recovery and Education   (United States)

^bs LifeNet Health   (United States)

^bt National Disease Research Interchange   (United States)

^bu UNYTS   (United States)

^bv ROSWELL PARK CANCER INSTITUTE   (United States)

^bw VAN ANDEL RESEARCH INSTITUTE   (United States)

^bx UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^bz FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^ca TEMPLE UNIVERSITY   (United States)

^cb VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^cc EUROPEAN BIOINFORMATICS INSTITUTE   (United Kingdom)

^cd University of California   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

EXPLORATION; GENE EXPRESSION; GENETIC VARIATION; META-ANALYSIS; PHENOTYPE; STATISTICAL ANALYSIS;

ARTICLE; CONTROLLED STUDY; EXPRESSION QUANTITATIVE TRAIT LOCUS; GENE EXPRESSION; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; PHENOTYPE; PUBLICATION; REGULATORY MECHANISM; STATISTICS; TISSUE SPECIFICITY; ANTIBODY SPECIFICITY; BIOLOGICAL MODEL; CHROMOSOMAL MAPPING; COMPUTER SIMULATION; HUMAN; META ANALYSIS (TOPIC); PROCEDURES; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICS AND NUMERICAL DATA;

CHROMOSOME MAPPING; COMPUTER SIMULATION; GENE EXPRESSION; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; META-ANALYSIS AS TOPIC; MODELS, GENETIC; ORGAN SPECIFICITY; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI;

EID: 85046840811     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-018-03621-1     Document Type: Article

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