A Sialylated Voltage-Dependent Ca 2+ Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells

Cell Host and Microbe

Volumn 23, Issue 6, 2018, Pages 809-818.e5

  Fujioka, Yoichiro ^a   Nishide, Shinya ^a,e   Ose, Toyoyuki ^b   Suzuki, Tadaki ^c   Kato, Izumi ^b   Fukuhara, Hideo ^b   Fujioka, Mari ^a   Horiuchi, Kosui ^a   Satoh, Aya O ^a   Nepal, Prabha ^a   Kashiwagi, Sayaka ^a   Wang, Jing ^a   Horiguchi, Mika ^a   Sato, Yuko ^c   Paudel, Sarad ^a   Nanbo, Asuka ^a   Miyazaki, Tadaaki ^b   Hasegawa, Hideki ^c   Maenaka, Katsumi ^b   Ohba, Yusuke ^a,d  

^a HOKKAIDO UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^d MARINE BIOLOGICAL LABORATORY   (United States)

^e HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

Author keywords

calcium channel; calcium channel blockers; calcium ion; hemagglutinin; influenza A virus; sialylation; virus entry; virus host cell interaction

Indexed keywords

AMLODIPINE; ASPARAGINE; CELL SURFACE PROTEIN; DILTIAZEM; INFLUENZA VIRUS HEMAGGLUTININ; OSELTAMIVIR; SIALIC ACID; UNCLASSIFIED DRUG; VERAPAMIL; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED CALCIUM CHANNEL CAV1.2; CACNA1C PROTEIN, HUMAN; CACNA1C PROTEIN, MOUSE; CALCIUM CHANNEL L TYPE;

A-431 CELL LINE; A-549 CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEAS-2B CELL LINE; BODY WEIGHT CHANGE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL SURFACE; CONTROLLED STUDY; COS-1 CELL LINE; DRUG CYTOTOXICITY; ENDOCYTOSIS; FEMALE; GENE KNOCKDOWN; HEK293T CELL LINE; HELA CELL LINE; HOST CELL; HUMAN; HUMAN CELL; IC95; IN VITRO STUDY; IN VIVO STUDY; INFLUENZA A; INFLUENZA A VIRUS; MALE; MEMBRANE BINDING; MOUSE; NASAL LAVAGE FLUID; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN GLYCOSYLATION; SIALYLATION; SURVIVAL RATE; VIRAL PLAQUE ASSAY; VIRUS ATTACHMENT; VIRUS CELL INTERACTION; VIRUS ENTRY; VIRUS PARTICLE; VIRUS REPLICATION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CHLOROCEBUS AETHIOPS; CV-1 CELL LINE; DOG; GENETICS; HEK293 CELL LINE; INFLUENZA; MDCK CELL LINE; METABOLISM; ORTHOMYXOVIRUS INFECTION; PATHOLOGY; PHYSIOLOGY; VIROLOGY;

A549 CELLS; ANIMALS; CALCIUM CHANNELS, L-TYPE; CERCOPITHECUS AETHIOPS; COS CELLS; DOGS; HEK293 CELLS; HELA CELLS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA A VIRUS; INFLUENZA, HUMAN; MADIN DARBY CANINE KIDNEY CELLS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; ORTHOMYXOVIRIDAE INFECTIONS;

EID: 85046837465     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2018.04.015     Document Type: Article

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