Constitutively active follicle-stimulating hormone receptor enables androgen-independent spermatogenesis

Journal of Clinical Investigation

Volumn 128, Issue 5, 2018, Pages 1787-1792

  Oduwole, Olayiwola O ^h   Peltoketo, Hellevi ^a,h   Poliandri, Ariel ^b,h   Vengadabady, Laura ^c   Chrusciel, Marcin ^d   Doroszko, Milena ^d   Samanta, Luna ^e   Owen, Laura ^f   Keevil, Brian ^f   Rahman, Nafis A ^d,g   Huhtaniemi, Ilpo T ^d,h  

^a UNIVERSITY OF OULU   (Finland)

^b ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

^d UNIVERSITY OF TURKU   (Finland)

^e RAVENSHAW UNIVERSITY   (India)

^f MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^g MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

^h HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYTOCHROME P450; CYTOCHROME P450 FAMILY 17A1; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FLUTAMIDE; FOLLITROPIN; FOLLITROPIN RECEPTOR; GONADOTROPIN; LUTEINIZING HORMONE; LUTEINIZING HORMONE RECEPTOR; MESSENGER RNA; TESTOSTERONE; TRANSCRIPTION FACTOR GATA 1; UNCLASSIFIED DRUG; LHCGR PROTEIN, MOUSE;

ANDROGEN DEFICIENCY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AZOOSPERMIA; FOLLITROPIN BLOOD LEVEL; GENE EXPRESSION; HORMONAL REGULATION; HYPOPHYSIS ADENOMA; IMMUNOHISTOCHEMISTRY; LEYDIG CELL; LUTEINIZING HORMONE BLOOD LEVEL; MALE; MALE FERTILITY; MOUSE; NONHUMAN; OLIGOSPERMIA; PASQUALINI SYNDROME; PATHOGENESIS; PRIORITY JOURNAL; SEMINIFEROUS TUBULE; SERTOLI CELL; SPERMATID; SPERMATOGENESIS; SPERMATOGONIUM; TELEOST; TESTIS WEIGHT; TRANSGENIC MOUSE; ANIMAL; GENETICS; METABOLISM;

ANDROGENS; ANIMALS; FOLLICLE STIMULATING HORMONE; LEYDIG CELLS; MALE; MICE; MICE, TRANSGENIC; RECEPTORS, FSH; RECEPTORS, LH; SERTOLI CELLS; SPERMATOGENESIS; TESTOSTERONE;

EID: 85046482445     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI96794     Document Type: Article

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