Overlapping dose responses of spermatogenic and extragonadal testosterone actions jeopardize the principle of hormonal male contraception

FASEB Journal

Volumn 28, Issue 6, 2014, Pages 2566-2576

  Oduwole, Olayiwola O ^a   Vydra, Natalia ^a,c   Wood, Nicholas E M ^a   Samanta, Luna ^a,d   Owen, Laura ^e   Keevil, Brian ^e   Donaldson, Mandy ^f   Naresh, Kikkeri ^b   Huhtaniemi, Ilpo T ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

^c INSTITUTE OF ONCOLOGY   (Poland)

^d RAVENSHAW UNIVERSITY   (India)

^e MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^f CHARING CROSS HOSPITAL   (United Kingdom)

Author keywords

Azoospermia; Hypothalamicpituitary testicular axis; Oligozoospermia

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; GESTAGEN; LUTEINIZING HORMONE RECEPTOR; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AZOOSPERMIA; CONTRACEPTION; CONTROLLED STUDY; DISEASE SEVERITY; HYPOGONADISM; KNOCKOUT MOUSE; LIBIDO; MALE; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; OLIGOSPERMIA; PRIORITY JOURNAL; SEXUAL BEHAVIOR; SEXUAL FUNCTION; SPERMATOGENESIS; TESTIS; TESTOSTERONE SYNTHESIS;

AZOOSPERMIA; HYPOTHALAMIC-PITUITARY-TESTICULAR AXIS; OLIGOZOOSPERMIA;

ANIMALS; AZOOSPERMIA; CONTRACEPTION; GONADOTROPINS; LUTEINIZING HORMONE; MALE; MICE; MICE, KNOCKOUT; RECEPTORS, LH; SEXUAL BEHAVIOR, ANIMAL; SPERMATOGENESIS; TESTIS; TESTOSTERONE;

EID: 84901818876     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-249219     Document Type: Article

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