Estrogen induces St6gal1 expression and increases IgG sialylation in mice and patients with rheumatoid arthritis: A potential explanation for the increased risk of rheumatoid arthritis in postmenopausal women

Arthritis Research and Therapy

Volumn 20, Issue 1, 2018, Pages

  Engdahl, Cecilia ^a,b   Bondt, Albert ^c   Harre, Ulrike ^a   Raufer, Jasmin ^a   Pfeifle, René ^a   Camponeschi, Alessandro ^b   Wuhrer, Manfred ^c   Seeling, Michaela ^c   Mårtensson, Inga Lill ^b   Nimmerjahn, Falk ^d   Krönke, Gerhard ^a   Scherer, Hans U ^c   Forsblad d'Elia, Helena ^b,e   Schett, Georg ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^e UMEÅ UNIVERSITY   (Sweden)

Author keywords

Antibody sialylation; Estrogen; Female sex; Rheumatoid arthritis

Indexed keywords

ESTRADIOL; FC RECEPTOR; FC RECEPTOR GAMMA; IMMUNOGLOBULIN G; PROTEIN ST6GAL1; SIALYLTRANSFERASE; UNCLASSIFIED DRUG; BETA-D-GALACTOSIDE ALPHA 2-6-SIALYLTRANSFERASE; ESTROGEN; FC RECEPTOR IIB; OVALBUMIN; SIALIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; ESTROGEN ACTIVITY; FEMALE; GENE EXPRESSION REGULATION; HORMONE SUBSTITUTION; IMMUNOGLOBULIN PRODUCING CELL; LEUKOCYTE; MOUSE; NONHUMAN; OBSERVATIONAL STUDY; PATHOGENESIS; POSTMENOPAUSE; RHEUMATOID ARTHRITIS; RISK FACTOR; SIALYLATION; UPREGULATION; ANIMAL; B LYMPHOCYTE; C57BL MOUSE; DRUG EFFECT; ESTROGEN THERAPY; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; MIDDLE AGED; OVARIECTOMY; PROCEDURES;

ANIMALS; ARTHRITIS, RHEUMATOID; B-LYMPHOCYTES; ESTROGEN REPLACEMENT THERAPY; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; IMMUNOGLOBULIN G; MICE, INBRED C57BL; MIDDLE AGED; OVALBUMIN; OVARIECTOMY; POSTMENOPAUSE; RECEPTORS, IGG; SIALIC ACIDS; SIALYLTRANSFERASES;

EID: 85046280475     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/s13075-018-1586-z     Document Type: Article

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