Risk factors for non-motor symptoms in Parkinson's disease

The Lancet Neurology

Volumn 17, Issue 6, 2018, Pages 559-568

  Marinus, Johan ^a   Zhu, Kangdi ^a   Marras, Connie ^b   Aarsland, Dag ^c,d   van Hilten, Jacobus J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF STAVANGER   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPARKINSON AGENT;

APATHY; COGNITIVE DEFECT; DAYTIME SOMNOLENCE; DEMENTIA; DEPRESSION; DISEASE SEVERITY; HALLUCINATION; HUMAN; IMPULSE CONTROL DISORDER; INSOMNIA; PARKINSON DISEASE; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SYMPTOM; COMPLICATION; PSYCHOLOGY; SLEEP DISORDER;

APATHY; COGNITIVE DYSFUNCTION; DEMENTIA; DEPRESSIVE DISORDER; DISRUPTIVE, IMPULSE CONTROL, AND CONDUCT DISORDERS; HUMANS; PARKINSON DISEASE; RISK FACTORS; SLEEP WAKE DISORDERS;

EID: 85046151065     PISSN: 14744422     EISSN: 14744465     Source Type: Journal    
DOI: 10.1016/S1474-4422(18)30127-3     Document Type: Review

References (93)

1. Jellinger, KA, Neuropathology of sporadic Parkinson's disease: evaluation and changes of concepts. Mov Disord 27 (2012), 8–30.
2. Schapira, AHV, Chaudhuri, KR, Jenner, P, Non-motor features of Parkinson disease. Nat Rev Neurosci 18 (2017), 435–450.
3. Berg, D, Postuma, RB, Adler, CH, et al. MDS research criteria for prodromal Parkinson's disease. Mov Disord 30 (2015), 1600–1611.
4. Visser, M, van Rooden, SM, Verbaan, D, Marinus, J, Stiggelbout, AM, van Hilten, JJ, A comprehensive model of health-related quality of life in Parkinson's disease. J Neurol 255 (2008), 1580–1587.
5. van Uem, JM, Marinus, J, Canning, C, et al. Health-related quality of life in patients with Parkinson's disease—a systematic review based on the ICF model. Neurosci Biobehav Rev 61 (2016), 26–34.
6. Chaudhuri, KR, Martinez-Martin, P, Schapira, AH, et al. International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for Parkinson's disease: the NMSQuest study. Mov Disord 21 (2006), 916–923.
7. Aarsland, D, Andersen, K, Larsen, JP, Lolk, A, Kragh-Sørensen, P, Prevalence and characteristics of dementia in Parkinson disease: an 8-year prospective study. Arch Neurol 60 (2003), 387–392.
8. Biglan, KM, Holloway, RG Jr, McDermott, MP, Richard, IH, Risk factors for somnolence, edema, and hallucinations in early Parkinson disease. Neurology 69 (2007), 187–195.
9. Gjerstad, MD, Wentzel-Larsen, T, Aarsland, D, Larsen, JP, Insomnia in Parkinson's disease: frequency and progression over time. J Neurol Neurosurg Psychiatry 78 (2007), 476–479.
10. Hobson, P, Meara, J, Risk and incidence of dementia in a cohort of older subjects with Parkinson's disease in the United Kingdom. Mov Disord 19 (2004), 1043–1049.
11. Hughes, TA, Ross, HF, Musa, S, et al. A 10-year study of the incidence of and factors predicting dementia in Parkinson's disease. Neurology 54 (2000), 1596–1602.
12. Levy, G, Tang, MX, Cote, LJ, et al. Motor impairment in PD: relationship to incident dementia and age. Neurology 55 (2000), 539–544.
13. Aarsland, D, Kurz, MW, The epidemiology of dementia associated with Parkinson's disease. Brain Pathol 20 (2010), 633–639.
14. Broeders, M, Velseboer, DC, de Bie, R, et al. Cognitive change in newly-diagnosed patients with Parkinson's disease: a 5-year follow-up study. J Int Neuropsychol Soc 19 (2013), 695–708.
15. Dubois, B, Burn, D, Goetz, C, et al. Diagnostic procedures for Parkinson's disease dementia: recommendations from the movement disorder society task force. Mov Disord 22 (2007), 2314–2324.
16. Litvan, I, Goldman, JG, Troster, AI, et al. Diagnostic criteria for mild cognitive impairment in Parkinson's disease: movement disorder society task force guidelines. Mov Disord 27 (2012), 349–356.
17. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, DSM-5. 2013, American Psychiatric Publishing, Washington, DC.
18. Johns, MW, Sensitivity and specificity of the multiple sleep latency test (MSLT), the maintenance of wakefulness test and the epworth sleepiness scale: failure of the MSLT as a gold standard. J Sleep Res 9 (2000), 5–11.
19. Marinus, J, Visser, M, van Hilten, JJ, Lammers, GJ, Stiggelbout, AM, Assessment of sleep and sleepiness in Parkinson disease. Sleep 26 (2003), 1049–1054.
20. Chaudhuri, KR, Pal, S, DiMarco, A, et al. The Parkinson's disease sleep scale: a new instrument for assessing sleep and nocturnal disability in Parkinson's disease. J Neurol Neurosurg Psychiatry 73 (2002), 629–635.
21. Buysse, DJ, Reynolds, CF 3rd, Monk, TH, Berman, SR, Kupfer, DJ, The Pittsburgh sleep quality index: a new instrument for psychiatric practice and research. Psychiatry Res 28 (1989), 193–213.
22. Weintraub, D, Mamikonyan, E, Papay, K, Shea, JA, Xie, SX, Siderowf, A, Questionnaire for impulsive-compulsive disorders in Parkinson's disease-rating scale. Mov Disord 27 (2012), 242–247.
23. Williams-Gray, CH, Mason, SL, Evans, JR, et al. The CamPaIGN study of Parkinson's disease: 10-year outlook in an incident population-based cohort. J Neurol Neurosurg Psychiatry 84 (2013), 1258–1264.
24. Cilia, R, Cereda, E, Klersy, C, et al. Parkinson's disease beyond 20 years. J Neurol Neurosurg Psychiatry 86 (2015), 849–855.
25. Pedersen, KF, Larsen, JP, Tysnes, OB, Alves, G, Natural course of mild cognitive impairment in Parkinson disease: a 5-year population-based study. Neurology 88 (2017), 767–774.
26. Chen, L, Yu, C, Zhang, N, Liu, J, Liu, W, Cognitive impairment in patients with Parkinson's disease: a 30-month follow-up study. Clin Neurol Neurosurg 151 (2016), 65–69.
27. Galtier, I, Nieto, A, Lorenzo, JN, Barroso, J, Mild cognitive impairment in Parkinson's disease: diagnosis and progression to dementia. J Clin Exp Neuropsychol 38 (2016), 40–50.
28. Hindle, JV, Hurt, CS, Burn, DJ, et al. The effects of cognitive reserve and lifestyle on cognition and dementia in Parkinson's disease—a longitudinal cohort study. Int J Geriatr Psychiatry 31 (2016), 13–23.
29. Hong, JY, Sunwoo, MK, Chung, SJ, et al. Subjective cognitive decline predicts future deterioration in cognitively normal patients with Parkinson's disease. Neurobiol Aging 35 (2014), 1739–1743.
30. Kandiah, N, Narasimhalu, K, Lau, PN, Seah, SH, Au, WL, Tan, LC, Cognitive decline in early Parkinson's disease. Mov Disord 24 (2009), 605–608.
31. Kwon, KY, Kang, SH, Kim, M, et al. Nonmotor symptoms and cognitive decline in de novo Parkinson's disease. Can J Neurol Sci 41 (2014), 597–602.
32. Muslimović D, Post, B, Speelman, JD, De Haan, RJ, Schmand, B, Cognitive decline in Parkinson's disease: a prospective longitudinal study. J Int Neuropsychol Soc 15 (2009), 426–437.
33. Pigott, K, Rick, J, Xie, SX, et al. Longitudinal study of normal cognition in Parkinson disease. Neurology 85 (2015), 1276–1282.
34. Schneider, JS, Elm, JJ, Parashos, SA, Ravina, BM, Galpern, WR, Predictors of cognitive outcomes in early Parkinson disease patients: The National Institutes of Health Exploratory Trials in Parkinson Disease (NET-PD) experience. Parkinsonism Relat Disord 16 (2010), 507–512.
35. Schrag, A, Siddiqui, UF, Anastasiou, Z, Weintraub, D, Schott, JM, Clinical variables and biomarkers in prediction of cognitive impairment in patients with newly diagnosed Parkinson's disease: a cohort study. Lancet Neurol 16 (2017), 66–75.
36. Stepkina, DA, Zakharov, VV, Yakhno, NN, Cognitive impairments in progression of Parkinson's disease. Neurosci Behav Physiol 40 (2010), 61–67.
37. Uc, EY, McDermott, MP, Marder, KS, et al. Incidence of and risk factors for cognitive impairment in an early Parkinson disease clinical trial cohort. Neurology 73 (2009), 1469–1477.
38. Zhu, K, van Hilten, JJ, Marinus, J, Predictors of dementia in Parkinson's disease; findings from a 5-year prospective study using the SCOPA-COG. Parkinsonism Relat Disord 20 (2014), 980–985.
39. Ahmadi-Abhari, S, Guzman-Castillo, M, Bandosz, P, et al. Temporal trend in dementia incidence since 2002 and projections for prevalence in England and Wales to 2040: modelling study. BMJ, 358, 2017, j2856.
40. Alves, G, Müller, B, Herlofson, K, et al. Incidence of Parkinson's disease in Norway: the Norwegian ParkWest study. J Neurol Neurosurg Psychiatry 80 (2009), 851–857.
41. Hall, H, Reyes, S, Landeck, N, et al. Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson's disease. Brain 137 (2014), 2493–2508.
42. van Rooden, SM, Visser, M, Verbaan, D, Marinus, J, van Hilten, JJ, Patterns of motor and non-motor features in Parkinson's disease. J Neurol Neurosurg Psychiatry 80 (2009), 846–850.
43. van der Heeden, JF, Marinus, J, Martinez-Martin, P, van Hilten, JJ, Importance of nondopaminergic features in evaluating disease severity of Parkinson disease. Neurology 82 (2014), 412–418.
44. Pagonabarraga, J, Martinez-Horta, S, Fernández de Bobadilla, R, et al. Minor hallucinations occur in drug-naive Parkinson's disease patients, even from the premotor phase. Mov Disord 31 (2016), 45–52.
45. de la Riva, P, Smith, K, Xie, SX, Weintraub, D, Course of psychiatric symptoms and global cognition in early Parkinson disease. Neurology 83 (2014), 1096–1103.
46. Forsaa, EB, Larsen, JP, Wentzel-Larsen, T, et al. A 12-year population-based study of psychosis in Parkinson disease. Arch Neurol 67 (2010), 996–1001.
47. Bjornestad, A, Pedersen, KF, Tysnes, OB, Alves, G, Clinical milestones in Parkinson's disease: a 7-year population-based incident cohort study. Parkinsonism Relat Disord 42 (2017), 28–33.
48. Barrett, MJ, Smolkin, ME, Flanigan, JL, Shah, BB, Harrison, MB, Sperling, SA, Characteristics, correlates, and assessment of psychosis in Parkinson disease without dementia. Parkinsonism Relat Disord 43 (2017), 56–60.
49. Fenelon, G, Soulas, T, Zenasni, F, Cleret de Langavant, L, The changing face of Parkinson's disease-associated psychosis: a cross-sectional study based on the new NINDS-NIMH criteria. Mov Disord 25 (2010), 763–766.
50. Gibson, G, Mottram, PG, Burn, DJ, et al. Frequency, prevalence, incidence and risk factors associated with visual hallucinations in a sample of patients with Parkinson's disease: a longitudinal 4-year study. Int J Geriatr Psychiatry 28 (2013), 626–631.
51. Morgante, L, Colosimo, C, Antonini, A, et al. Psychosis associated to Parkinson's disease in the early stages: relevance of cognitive decline and depression. J Neurol Neurosurg Psychiatry 83 (2012), 76–82.
52. Zhu, K, van Hilten, JJ, Putter, H, Marinus, J, Risk factors for hallucinations in Parkinson's disease: results from a large prospective cohort study. Mov Disord 28 (2013), 755–762.
53. Fernandez, HH, Aarsland, D, Fénelon, G, et al. Scales to assess psychosis in Parkinson's disease: critique and recommendations. Mov Disord 23 (2008), 484–500.
54. Del Tredici, K, Braak, H, Review: sporadic Parkinson's disease: development and distribution of α-synuclein pathology. Neuropathol Appl Neurobiol 42 (2016), 33–50.
55. Jellinger, KA, Neuropathobiology of non-motor symptoms in Parkinson disease. J Neural Transm (Vienna) 122 (2015), 1429–1440.
56. Lenka, A, Hegde, S, Jhunjhunwala, KR, Pal, PK, Interactions of visual hallucinations, rapid eye movement sleep behavior disorder and cognitive impairment in Parkinson's disease: a review. Parkinsonism Relat Disord 22 (2016), 1–8.
57. Suzuki, K, Miyamoto, M, Miyamoto, T, Hirata, K, Parkinson's disease and sleep/wake disturbances. Curr Neurol Neurosci Rep, 15, 2015, 8.
58. Scott, NW, Macleod, AD, Counsell, CE, Motor complications in an incident Parkinson's disease cohort. Eur J Neurol 23 (2016), 304–312.
59. Oh, YS, Kim, JS, Lee, PH, Effect of rivastigmine on behavioral and psychiatric symptoms of Parkinson's disease dementia. J Mov Disord 8 (2015), 98–102.
60. Marsh, L, McDonald, WM, Cummings, J, Ravina, B, Provisional diagnostic criteria for depression in Parkinson's disease: report of an NINDS/NIMH work group. Mov Disord 21 (2006), 148–158.
61. Becker, C, Brobert, GP, Johansson, S, Jick, SS, Meier, CR, Risk of incident depression in patients with Parkinson disease in the UK. Eur J Neurol 18 (2011), 448–453.
62. Goodarzi, Z, Mrklas, KJ, Roberts, DJ, Jette, N, Pringsheim, T, Holroyd-Leduc, J, Detecting depression in Parkinson disease: a systematic review and meta-analysis. Neurology 87 (2016), 426–437.
63. Jasinska-Myga, B, Putzke, JD, Wider, C, Wszolek, ZK, Uitti, RJ, Depression in Parkinson's disease. Can J Neurol Sci 37 (2010), 61–66.
64. Wee, N, Kandiah, N, Acharyya, S, et al. Depression and anxiety are co-morbid but dissociable in mild Parkinson's disease: a prospective longitudinal study of patterns and predictors. Parkinsonism Relat Disord 23 (2016), 50–56.
65. Zhu, K, van Hilten, JJ, Marinus, J, Associated and predictive factors of depressive symptoms in patients with Parkinson's disease. J Neurol 263 (2016), 1215–1225.
66. den Brok, MG, van Dalen, JW, van Gool, WA, Moll van Charante, EP, de Bie, RM, Richard, E, Apathy in Parkinson's disease: a systematic review and meta-analysis. Mov Disord 30 (2015), 759–769.
67. Schiehser, DM, Liu, L, Lessig, SL, et al. Predictors of discrepancies in Parkinson's disease patient and caregiver ratings of apathy, disinhibition, and executive dysfunction before and after diagnosis. J Int Neuropsychol Soc 19 (2013), 295–304.
68. Oguru, M, Tachibana, H, Toda, K, Okuda, B, Oka, N, Apathy and depression in Parkinson disease. J Geriatr Psychiatry Neurol 23 (2010), 35–41.
69. Wee, N, Kandiah, N, Acharyya, S, et al. Baseline predictors of worsening apathy in Parkinson's disease: a prospective longitudinal study. Parkinsonism Relat Disord 23 (2016), 95–98.
70. Zahodne, LB, Marsiske, M, Okun, MS, Rodriguez, RL, Malaty, I, Bowers, D, Mood and motor trajectories in Parkinson's disease: multivariate latent growth curve modeling. Neuropsychology 26 (2012), 71–80.
71. Pedersen, KF, Alves, G, Aarsland, D, Larsen, JP, Occurrence and risk factors for apathy in Parkinson disease: a 4-year prospective longitudinal study. J Neurol Neurosurg Psychiatry 80 (2009), 1279–1282.
72. Santangelo, G, Vitale, C, Trojano, L, et al. Relationship between apathy and cognitive dysfunctions in de novo untreated Parkinson's disease: a prospective longitudinal study. Eur J Neurol 22 (2015), 253–260.
73. Clarke, DE, Ko, JY, Lyketsos, C, Rebok, GW, Eaton, WW, Apathy and cognitive and functional decline in community-dwelling older adults: results from the Baltimore ECA longitudinal study. Int Psychogeriatrics 22 (2010), 819–829.
74. Chahine, LM, Amara, AW, Videnovic, A, A systematic review of the literature on disorders of sleep and wakefulness in Parkinson's disease from 2005 to 2015. Sleep Med Rev 35 (2017), 33–50.
75. Zhu, K, van Hilten, JJ, Marinus, J, Course and risk factors for excessive daytime sleepiness in Parkinson's disease. Parkinsonism Relat Disord 24 (2016), 34–40.
76. Spindler, M, Gooneratne, NS, Siderowf, A, Duda, JE, Cantor, C, Dahodwala, N, Daytime sleepiness is associated with falls in Parkinson's disease. J Parkinsons Dis 3 (2013), 387–391.
77. Tholfsen, LK, Larsen, JP, Schulz, J, Tysnes, OB, Gjerstad, MD, Development of excessive daytime sleepiness in early Parkinson disease. Neurology 85 (2015), 162–168.
78. Knie, B, Mitra, MT, Logishetty, K, Chaudhuri, KR, Excessive daytime sleepiness in patients with Parkinson's disease. CNS Drugs 25 (2011), 203–212.
79. Barone, P, Antonini, A, Colosimo, C, et al. The PRIAMO study: a multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson's disease. Mov Disord 24 (2009), 1641–1649.
80. Tholfsen, LK, Larsen, JP, Schulz, J, Tysnes, OB, Gjerstad, MD, Changes in insomnia subtypes in early Parkinson disease. Neurology 88 (2017), 352–358.
81. Zhu, K, van Hilten, JJ, Marinus, J, The course of insomnia in Parkinson's disease. Parkinsonism Relat Disord 33 (2016), 51–57.
82. Schrempf, W, Brandt, MD, Storch, A, Reichmann, H, Sleep disorders in Parkinson's disease. J Parkinsons Dis 4 (2014), 211–221.
83. Jaakkola, E, Kaasinen, V, Siri, C, et al. Impulse control disorders are associated with multiple psychiatric symptoms in Parkinson's disease. J Parkinsons Dis 4 (2014), 507–515.
84. Antonini, A, Siri, C, Santangelo, G, et al. Impulsivity and compulsivity in drug-naive patients with Parkinson's disease. Mov Disord 26 (2011), 464–468.
85. Phu, AL, Xu, Z, Brakoulias, V, et al. Effect of impulse control disorders on disability and quality of life in Parkinson's disease patients. J Clin Neurosci 21 (2014), 63–66.
86. Leroi, I, Harbishettar, V, Andrews, M, McDonald, K, Byrne, EJ, Burns, A, Carer burden in apathy and impulse control disorders in Parkinson's disease. Int J Geriatr Psychiatry 27 (2012), 160–166.
87. Joutsa, J, Martikainen, K, Vahlberg, T, Kaasinen, V, Effects of dopamine agonist dose and gender on the prognosis of impulse control disorders in Parkinson's disease. Parkinsonism Relat Disord 18 (2012), 1079–1083.
88. Kraemmer, J, Smith, K, Weintraub, D, et al. Clinical-genetic model predicts incident impulse control disorders in Parkinson's disease. J Neurol Neurosurg Psychiatry 87 (2016), 1106–1111.
89. Weintraub, D, Koester, J, Potenza, MN, et al. Impulse control disorders in Parkinson disease: a cross-sectional study of 3090 patients. Arch Neurol 67 (2010), 589–595.
90. Mamikonyan, E, Siderowf, AD, Duda, JE, et al. Long-term follow-up of impulse control disorders in Parkinson's disease. Mov Disord 23 (2008), 75–80.
91. Taylor, DJ, Lichstein, KL, Durrence, HH, Reidel, BW, Bush, AJ, Epidemiology of insomnia, depression, and anxiety. Sleep 28 (2005), 1457–1464.
92. Avila, A, Cardona, X, Bello, J, Maho, P, Sastre, F, Martin-Baranera, M, Impulse control disorders and punding in Parkinson's disease: the need for a structured interview. Neurologia 26 (2011), 166–172 (in Spanish).
93. Braak, H, Ghebremedhin, E, Rüb, U, Bratzke, H, Del Tredici, K, Stages in the development of Parkinson's disease-related pathology. Cell Tissue Res 318 (2004), 121–134.