Effects of psychological interventions on systemic levels of inflammatory biomarkers in humans: A systematic review and meta-analysis

Brain, Behavior, and Immunity

Volumn 74, Issue , 2018, Pages 68-78

  O'Toole, M S ^a   Bovbjerg, D H ^b   Renna, M E ^c   Lekander, M ^d,e   Mennin, D S ^c   Zachariae, R ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^c Howard Hughes Medical Institute   (United States)

^d KAROLINSKA INSTITUTE   (Sweden)

^e STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Cancer; CRP; Cytokines; Depression; Inflammation; Psychotherapy

Indexed keywords

C REACTIVE PROTEIN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR; BIOLOGICAL MARKER; CYTOKINE;

ARTICLE; CLINICAL EFFECTIVENESS; COGNITIVE THERAPY; DISEASE ASSOCIATION; DISTRESS SYNDROME; FOLLOW UP; HUMAN; META ANALYSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PSYCHOTHERAPY; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); SYSTEMATIC REVIEW; ADULT; COGNITIVE BEHAVIORAL THERAPY; IMMUNOLOGY; INFLAMMATION; MENTAL DISEASE; MENTAL HEALTH; PATHOPHYSIOLOGY; PROCEDURES; PSYCHOLOGY;

ADULT; BIOMARKERS; COGNITIVE BEHAVIORAL THERAPY; CYTOKINES; HUMANS; INFLAMMATION; MENTAL DISORDERS; MENTAL HEALTH; PSYCHOLOGY, APPLIED; PSYCHOTHERAPY;

EID: 85046121172     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2018.04.005     Document Type: Article

References (74)

1. Allin, K.H., Bojesen, S.E., Johansen, J.S., Nordestgaard, B.G., Cancer risk by combined levels of YKL-40 and C-reactive protein in the general population. Br. J. Cancer 106 (2012), 199–205, 10.1038/bjc.2011.501.
2. Bae, B.G., Oh, S.H., Park, C.O., Noh, S., Noh, J.Y., Kim, K.R., Lee, K.H., Progressive muscle relaxation therapy for atopic dermatitis: objective assessment of efficacy. Acta Derm. Venereol. 92 (2012), 57–61, 10.2340/00015555-1189.
3. Banchereau, J., Pascual, V., O'Garra, A., From IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokines. Nat. Immunol. 13 (2012), 925–931, 10.1038/ni.2406.
4. Borenstein, M., Hedges, L.V., Higgins, J.P.T., Rothstein, H.R., Introduction to meta-Analysis. 2009, John Wiley & Sons Ltd, Chichester, UK 10.1002/9780470743386.
5. Bower, J.E., Irwin, M.R., Mind-body therapies and control of inflammatory biology: a descriptive review. Brain. Behav. Immun. 51 (2016), 1–11, 10.1016/j.bbi.2015.06.012.
6. Carpenter, J.K., Andrews, L.A., Witcraft, S.M., Powers, M.B., Smits, J.A.J., Hofmann, S.G., Cognitive behavioral therapy for anxiety and related disorders: a meta-analysis of randomized placebo-controlled trials. Depress Anxiety, 2018 10.1002/da.22728.
7. Chan, D.S.M., Bandera, E.V., Greenwood, D.C., Norat, T., Circulating C-Reactive Protein and breast cancer risk–Systematic literature review and meta-analysis of prospective cohort studies. Cancer Epidemiol. Biomarkers Prev. 24 (2015), 1439–1449, 10.1158/1055-9965.EPI-15-0324.
8. Chen, H.-Y., Chiang, C.-K., Wang, H.-H., Hung, K.-Y., Lee, Y.-J., Peng, Y.-S., Wu, K.-D., Tsai, T.-J., Cognitive-behavioral therapy for sleep disturbance in patients undergoing peritoneal dialysis: a pilot randomized controlled trial. Am. J. Kidney Dis., 52, 2008, 314, 10.1053/j.ajkd.2008.03.012.
9. Chrysohoou, C., Kollia, N., Tousoulis, D., The link between depression and atherosclerosis through the pathways of inflammation and endothelium dysfunction. Maturitas 109 (2018), 1–5, 10.1016/j.maturitas.2017.12.001.
10. Cohen, J., Statistical power analysis for the behavioral sciences. 2nd ed., 1988, Lawrence Erlbaum, Hillsdale.
11. Comprehensive meta-analysis [computer program]. Version 3.3.070. Eaglewood, NJ: Biostat; 2014.
12. Conway, D.S., Buggins, P., Hughes, E., Lip, G.Y., Prognostic significance of raised plasma levels of interleukin-6 and C-reactive protein in atrial fibrillation. Am. Heart J. 148 (2004), 462–466, 10.1016/j.ahj.2004.01.026.
13. Creswell, J.D., Irwin, M.R., Burklund, L.J., Lieberman, M.D., Arevalo, J.M., Ma, J., Breen, E.C., Cole, S.W., Mindfulness-Based Stress Reduction training reduces loneliness and pro-inflammatory gene expression in older adults: a small randomized controlled trial. Brain Behav. Immun. 26 (2012), 1095–1101, 10.1016/j.bbi.2012.07.006.
14. Cuijpers, P., Berking, M., Andersson, G., Quigley, L., Kleiboer, A., Dobson, K.S., A meta-analysis of cognitive-behavioural therapy for adult depression, alone and in comparison with other treatments. Can. J. Psychiatry 58 (2013), 376–385, 10.1177/070674371305800702.
15. Cuijpers, P., van Straten, A., van Schaik, A., Andersson, G., Psychological treatment of depression in primary care: a meta-analysis. Br. J. Gen. Pract. 59 (2009), 51–60, 10.3399/bjgp09X395139.
16. D'Mello, C., Swain, M.G., Immune-to-brain communication pathways in Inflammation-associated sickness and depression. Curr. Top. Behav. Neurosci. 31 (2017), 73–94, 10.1007/7854_2016_37.
17. Dantzer, R., Capuron, L., Inflammation-associated depression: evidence, mechanisms and implications. 2017, Springer Intervational Publishing, Cham, Switzerland.
18. Diakos, C.I., Charles, K.A., McMillan, D.C., Clarke, S.J., Cancer-related inflammation and treatment effectiveness. Lancet Oncol. 15 (2014), e493–e503, 10.1016/S1470-2045(14)70263-3.
19. Doering, L.V., Cross, R., Vredevoe, D., Martinez-Maza, O., Cowan, M.J., Infection, depression, and immunity in women after coronary artery bypass: a pilot study of cognitive behavioral therapy. Altern. Ther. Health Med. 13 (2007), 18–21.
20. Duval, S., Tweedie, R., Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics 56 (2000), 455–463.
21. Egger, M., Davey Smith, G., Schneider, M., Minder, C., Bias in meta-analysis detected by a simple, graphical test. Br. Med. J. 315 (1997), 629–634.
22. Eisenberger, N.I., Moieni, M., Inagaki, T.K., Muscatell, K.A., Irwin, M.R., In sickness and in health: the co-regulation of inflammation and social behavior. Neuropsychopharmacology 42 (2017), 242–253, 10.1038/npp.2016.141.
23. Eremin, O., Walker, M.B., Simpson, E., Heys, S.D., Ah-See, A.K., Hutcheon, A.W., Ogston, K.N., Sarkar, T.K., Segar, A., Walker, L.G., 2009. Immuno-modulatory effects of relaxation training and guided imagery in women with locally advanced breast cancer undergoing multimodality therapy: a randomised controlled trial. Breast 18, 17–25. https://doi.org/http://dx.doi.org/10.1016/j.breast.2008.09.002.
24. Farver-Vestergaard, I., Jacobsen, D., Zachariae, R., Efficacy of psychosocial interventions on psychological and physical health outcomes in chronic obstructive pulmonary disease: a systematic review and meta-analysis. Psychother. Psychosom. 84 (2015), 37–50, 10.1159/000367635.
25. Filiano, A.J., Gadani, S.P., Kipnis, J., How and why do T cells and their derived cytokines affect the injured and healthy brain?. Nat. Rev. Neurosci. 18 (2017), 375–384, 10.1038/nrn.2017.39.
26. Gallegos, A.M., Hoerger, M., Talbot, N.L., Krasner, M.S., Knight, J.M., Moynihan, J.A., Duberstein, P.R., Toward identifying the effects of the specific components of Mindfulness-Based Stress Reduction on biologic and emotional outcomes among older adults. J. Altern. Complement. Med. 19 (2013), 787–792, 10.1089/acm.2012.0028.
27. Gleeson, M., Bishop, N.C., Stensel, D.J., Lindley, M.R., Mastana, S.S., Nimmo, M.A., The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease. Nat. Rev. Immunol. 11 (2011), 607–615, 10.1038/nri3041.
28. Greenland, S., O'Rourke, K., On the bias produced by quality scores in meta-analysis, and a hierarchical view of proposed solutions. Biostatistics 2 (2001), 463–471, 10.1093/biostatistics/2.4.463.
29. Halaris, A., Inflammation-associated co-morbidity between depression and cardiovascular disease. Curr. Top. Behav. Neurosci. 31 (2017), 45–70, 10.1007/7854_2016_28.
30. Hanahan, D., Weinberg, R.A., Hallmarks of cancer: the next generation. Cell 144 (2011), 646–674, 10.1016/j.cell.2011.02.013.
31. Hedges, L.V., Olkin, I., Statistical methods for meta-analysis. 1985, Academic Press.
32. Hedges, L.V., Pigott, T.D., The power of statistical tests in meta-analysis. Psychol. Methods 6 (2001), 203–217.
33. Higgins, J.P.T., Thompson, S.G., Quantifying heterogeneity in a meta-analysis. Stat. Med. 21 (2002), 1539–1558, 10.1002/sim.1186.
34. Hojman, P., Exercise protects from cancer through regulation of immune function and inflammation. Biochem. Soc. Trans. 45 (2017), 905–911, 10.1042/BST20160466.
35. Irwin, M.R., Olmstead, R., Carrillo, C., Sadeghi, N., Breen, E.C., Witarama, T., Yokomizo, M., Lavretsky, H., Carroll, J.E., Motivala, S.J., Bootzin, R., Nicassio, P., Cognitive behavioral therapy vs. Tai Chi for late life insomnia and inflammatory risk: a randomized controlled comparative efficacy trial. Sleep 37 (2014), 1543–1552, 10.5665/sleep.4008.
36. Jadad, A.R., Moore, R.A., Carroll, D., Jenkinson, C., Reynolds, D.J., Gavaghan, D.J., McQuay, H.J., Assessing the quality of reports of randomized clinical trials: is blinding necessary?. Control. Clin. Trials 17 (1996), 1–12.
37. Köhler, C.A., Freitas, T.H., Stubbs, B., Maes, M., Solmi, M., Veronese, N., de Andrade, N.Q., Morris, G., Fernandes, B.S., Brunoni, A.R., Herrmann, N., Raison, C.L., Miller, B.J., Lanctôt, K.L., Carvalho, A.F., Peripheral alterations in cytokine and chemokine levels after antidepressant drug treatment for major depressive disorder: systematic review and meta-analysis. Mol. Neurobiol., 1–12, 2017, 10.1007/s12035-017-0632-1.
38. Li, H., Liu, W., Xie, J., Circulating interleukin-6 levels and cardiovascular and all-cause mortality in the elderly population: a meta-analysis. Arch. Gerontol. Geriatr. 73 (2017), 257–262, 10.1016/j.archger.2017.08.007.
39. Li, J., Jiao, X., Yuan, Z., Qiu, H., Guo, R., C-reactive protein and risk of ovarian cancer. Medicine (Baltimore), 96, 2017, e7822, 10.1097/MD.0000000000007822.
40. Li, Y., Zhong, X., Cheng, G., Zhao, C., Zhang, L., Hong, Y., Wan, Q., He, R., Wang, Z., Hs-CRP and all-cause, cardiovascular, and cancer mortality risk: A meta-analysis. Atherosclerosis 259 (2017), 75–82, 10.1016/J.ATHEROSCLEROSIS.2017.02.003.
41. Lotrich, F., Inflammatory cytokines, growth factors, and depression. Curr. Pharm. Des. 18 (2012), 5920–5935, 10.2174/138161212803523680.
42. Marsik, C., Kazemi-Shirazi, L., Schickbauer, T., Winkler, S., Joukhadar, C., Wagner, O.F., Endler, G., C-Reactive Protein and all-cause mortality in a large hospital-based cohort. Clin. Chem. 54 (2008), 343–349, 10.1373/clinchem.2007.091959.
43. McCusker, R.H., Kelley, K.W., Immune-neural connections: how the immune system's response to infectious agents influences behavior. J. Exp. Biol. 216 (2013), 84–98, 10.1242/jeb.073411.
44. Melo, L.C., Dativo-Medeiros, J., Menezes-Silva, C.E., Barbosa, F.T., de Sousa-Rodrigues, C.F., Rabelo, L.A., Physical exercise on inflammatory markers in type 2 diabetes patients: A systematic review of randomized controlled trials. Oxid. Med. Cell. Longev. 2017 (2017), 1–10, 10.1155/2017/8523728.
45. Menzies, V., Lyon, D.E., Elswick, R.K.J., McCain, N.L., Gray, D.P., Effects of guided imagery on biobehavioral factors in women with fibromyalgia. J. Behav. Med. 37 (2014), 70–80, 10.1007/s10865-012-9464-7.
46. Moher, D., Shamseer, L., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., Shekelle, P., Stewart, L.A., Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst. Rev., 4, 2015, 1, 10.1186/2046-4053-4-1.
47. Morgan, N., Irwin, M.R., Chung, M., Wang, C., The effects of mind-body therapies on the immune system: Meta-analysis. PLoS One, 9, 2014, e100903, 10.1371/journal.pone.0100903.
48. Muñoz-Cánoves, P., Scheele, C., Pedersen, B.K., Serrano, A.L., Interleukin-6 myokine signaling in skeletal muscle: a double-edged sword?. FEBS J. 280 (2013), 4131–4148, 10.1111/febs.12338.
49. Nasef, N.A., Mehta, S., Ferguson, L.R., Susceptibility to chronic inflammation: an update. Arch. Toxicol. 91 (2017), 1131–1141, 10.1007/s00204-016-1914-5.
50. Nilsonne, G., Lekander, M., Åkerstedt, T., Axelsson, J., Ingre, M., Diurnal variation of circulating interleukin-6 in humans: A meta-analysis. PLoS One, 11, 2016, e0165799, 10.1371/journal.pone.0165799.
51. Oh, B., Butow, P., Mullan, B., Clarke, S., 2008. Medical qigong for cancer patients: pilot study of impact on quality of life, side effects of treatment and inflammation 36, 459–472. https://doi.org/http://dx.doi.org/10.1142/S0192415X08005904.
52. Oh, B., Butow, P., Mullan, B., Clarke, S., Beale, P., Pavlakis, N., Kothe, E., Lam, L., Rosenthal, D., Impact of Medical Qigong on quality of life, fatigue, mood and inflammation in cancer patients: a randomized controlled trial. Ann. Oncol. 21 (2010), 608–614, 10.1093/annonc/mdp479.
53. Oken, B.S., Fonareva, I., Haas, M., Wahbeh, H., Lane, J.B., Zajdel, D., Amen, A., Pilot Controlled Trial of Mindfulness Meditation and Education for Dementia Caregivers. J. Altern. Complement. Med. 16 (2010), 1031–1039, 10.1089/acm.2009.0733.
54. Pakiz, B., Flatt, S.W., Bardwell, W.A., Rock, C.L., Mills, P.J., Effects of a weight loss intervention on body mass, fitness, and inflammatory biomarkers in overweight or obese breast cancer survivors. Int. J. Behav. Med. 18 (2011), 333–341, 10.1007/s12529-010-9079-8.
55. Prasad, K., C-Reactive Protein (CRP)-Lowering Agents. Cardiovasc. Drug Rev. 24 (2006), 33–50, 10.1111/j.1527-3466.2006.00033.x.
56. Raison, C.L., Rutherford, R.E., Woolwine, B.J., Shuo, C., Schettler, P., Drake, D.F., Haroon, E., Miller, A.H., A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression. JAMA Psychiatry, 70, 2013, 31, 10.1001/2013.jamapsychiatry.4.
57. Reich, R.R., Lengacher, C.A., Klein, T.W., Newton, C., Shivers, S., Ramesar, S., Alinat, C.B., Paterson, C., Le, A., Park, J.Y., Johnson-Mallard, V., Elias, M., Moscoso, M., Goodman, M., Kip, K.E., A randomized controlled trial of the effects of Mindfulness-Based Stress Reduction (MBSR[BC]) on levels of inflammatory biomarkers among recovering breast cancer survivors. Biol. Res. Nurs. 19 (2017), 456–464, 10.1177/1099800417707268.
58. Richardson, M.A., Post-White, J., Grimm, E.A., Moye, L.A., Singletary, S.E., Justice, B., Coping, life attitudes, and immune responses to imagery and group support after breast cancer treatment. Altern. Ther. Heal. Med. 3 (1997), 62–70.
59. Ridker, P.M., High-sensitivity C-reactive protein as a predictor of all-cause mortality: implications for research and patient care. Clin. Chem. 54 (2008), 234–237, 10.1373/clinchem.2007.099465.
60. Rosenthal, R., The file drawer problem and tolerance for null results. Psychol. Bull. 86 (1979), 638–641, 10.1037/0033-2909.86.3.638.
61. Seekles, W., Cuijpers, P., Kok, R., Beekman, A., van Marwijk, H., van Straten, A., Psychological treatment of anxiety in primary care: a meta-analysis. Psychol. Med. 43 (2013), 351–361, 10.1017/S0033291712000670.
62. Shariq, A.S., Brietzke, E., Rosenblat, J.D., Barendra, V., Pan, Z., McIntyre, R.S., Targeting cytokines in reduction of depressive symptoms: A comprehensive review. Prog. Neuro-Psychopharmacol. Biol. Psychiatry 83 (2018), 86–91, 10.1016/j.pnpbp.2018.01.003.
63. Sharpe, L., Schrieber, L., A blind randomized controlled trial of cognitive versus behavioral versus cognitive-behavioral therapy for patients with rheumatoid arthritis. Psychother. Psychosom. 81 (2012), 145–152, 10.1159/000332334 [doi].
64. Sharpe, L., Sensky, T., Timberlake, N., Ryan, B., Brewin, C.R., Allard, S., 2001. A blind, randomized, controlled trial of cognitive-behavioural intervention for patients with recent onset rheumatoid arthritis: preventing psychological and physical morbidity. Pain 89, 275–283. https://doi.org/http://dx.doi.org/10.1016/S0304-3959(00)00379-1.
65. Sims, J.E., Smith, D.E., The IL-1 family: regulators of immunity. Nat. Rev. Immunol., 10, 2010, 117, 10.1038/nri2691.
66. Slavich, G.M., Understanding inflammation, its regulation, and relevance for health: a top scientific and public priority. Brain. Behav. Immun. 45 (2015), 13–14, 10.1016/j.bbi.2014.10.012.
67. Smith, K.J., Au, B., Ollis, L., Schmitz, N., The association between C-reactive protein, Interleukin-6 and depression among older adults in the community: a systematic review and meta-analysis. Exp. Gerontol. 102 (2018), 109–132, 10.1016/J.EXGER.2017.12.005.
68. Sterne, J.A.C., Egger, M., Moher, D., Adressing reporting biases. Higgins, J.P.T., Green, S., (eds.) Cochrane Handbook for Systematic Reviews of Intervention, 2008, Wiley-Blackwell Publishing, Chichester, UK, 297–333.
69. Taylor, C.B., Conrad, A., Wilhelm, F.H., Strachowski, D., Khaylis, A., Neri, E., Giese-Davis, J., Roth, W.T., Cooke, J.P., Kraemer, H., Spiegel, D., Does improving mood in depressed patients alter factors that may affect cardiovascular disease risk?. J. Psychiatr. Res. 43 (2009), 1246–1252, 10.1016/j.jpsychires.2009.05.006.
70. Walsh, E., Eisenlohr-Moul, T., Baer, R., 2016. Brief mindfulness training reduces salivary IL-6 and TNF-α in young women with depressive symptomatology. J. Consult. Clin. Psychol. 84, 887–897. https://doi.org/http://dx.doi.org/10.1037/ccp0000122.
71. Williamson, S., Munro, C., Pickler, R., Grap, M.J., Elswick, R.K., Comparison of biomarkers in blood and saliva in healthy adults. Nurs. Res. Pract. 2012 (2012), 1–4, 10.1155/2012/246178.
72. Wium-Andersen, M.K., Ørsted, D.D., Nielsen, S.F., Nordestgaard, B.G., Elevated C-Reactive Protein Levels, Psychological Distress, and Depression in 73 131 Individuals. JAMA Psychiatry, 70, 2013, 176, 10.1001/2013.jamapsychiatry.102.
73. Xu, W., Larbi, A., Immunity and Inflammation: from Jekyll to Hyde. Gerontol. Exp., 2017, 10.1016/J.EXGER.2017.11.018.
74. Zheng, R.-R., Huang, M., Jin, C., Wang, H.-C., Yu, J.-T., Zeng, L.-C., Zheng, F.-Y., Lin, F., Cervical cancer systemic inflammation score: a novel predictor of prognosis. Oncotarget 7 (2016), 15230–15242, 10.18632/oncotarget.7378.