Granule-stored MUC5B mucins are packed by the noncovalent formation of N-terminal head-to-head tetramers

Journal of Biological Chemistry

Volumn 293, Issue 15, 2018, Pages 5746-5754

  Trillo Muyo, Sergio ^a   Nilsson, Harriet E ^a,b,c   Recktenwald, Christian V ^a   Ermund, Anna ^a   Ridley, Caroline ^d   Meiss, Lauren N ^a   Bähr, Andrea ^e   Klymiuk, Nikolai ^e   Wine, Jeffrey J ^f   Koeck, Philip J B ^b,c   Thornton, David J ^d   Hebert, Hans ^b,c   Hansson, Gunnar C ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e UNIVERSITY OF MUNICH   (Germany)

^f STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULATION; MAMMALS; OLIGOMERS;

GLAND DUCTS; LONG LINEAR; N-TERMINALS; NON-COVALENT; SECRETORY GRANULES; SINGLE PARTICLE; UPPER AIRWAY; VIDEO MICROSCOPY;

DUCTS;

MUCIN 5B; CALCIUM; MUC5B PROTEIN, HUMAN; RECOMBINANT PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN STRUCTURE; PROTEIN UNFOLDING; TRANSMISSION ELECTRON MICROSCOPY; VIDEO MICROSCOPY; ANIMAL; CHEMISTRY; GENETICS; HUMAN; METABOLISM; PIG; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE;

ANIMALS; CALCIUM; HUMANS; HYDROGEN-ION CONCENTRATION; MUCIN-5B; PROTEIN DOMAINS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; RECOMBINANT PROTEINS; SWINE;

EID: 85045345527     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.RA117.001014     Document Type: Article

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