Identification of Molecular Intermediates in the Assembly Pathway of the MUC5AC Mucin

Journal of Biological Chemistry

Volumn 279, Issue 15, 2004, Pages 15698-15705

  Sheehan, John K ^a,b   Kirkham, Sara ^a   Howard, Marj ^a   Woodman, Philip ^a   Kutay, Saduman ^a   Brazeau, Caroline ^a   Buckley, Jeanette ^a   Thornton, David J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; DEPOLYMERIZATION; DIMERIZATION; DIMERS; ELECTROPHORESIS; GELS; MOLECULES; OLIGOMERS; POLYPEPTIDES; PROTEINS; REDUCTION;

ASSEMBLY PATHWAY; CELL LINES; MOLECULAR INTERMEDIATES; MUCINS;

BIOCHEMISTRY;

GLYCOPROTEIN; MUCIN; MUCIN 5AC; POLYPEPTIDE; VON WILLEBRAND FACTOR;

AGAR GEL ELECTROPHORESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ISOLATION; CELL POPULATION; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; DIMERIZATION; DISULFIDE BOND; GLYCOSYLATION; MOLECULAR INTERACTION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; SOLUBILIZATION; SPUTUM ANALYSIS;

CELL LINE, TUMOR; CENTRIFUGATION, DENSITY GRADIENT; CESIUM; CHLORIDES; DIMERIZATION; DISULFIDES; ELECTROPHORESIS, AGAR GEL; ENDOPLASMIC RETICULUM; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; MICROSCOPY, ELECTRON; MUCINS; PRECIPITIN TESTS; TIME FACTORS;

ANIMALIA; COLUMBA;

EID: 2442454780     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M313241200     Document Type: Article

References (29)

1. Carlstedt, I., Lindgren, H., Sheehan, J. K., Ulmsten, U., and Wingerup, L. (1983) Biochem. J. 211, 13-22
2. Carlstedt, I., and Sheehan, J. K. (1984) Biochem. Soc. Trans. 12, 61-63
3. Gupta, R., Jentoft, N., Jamieson, A. M., and Blackwell, J. (1990) Biopolymers 29, 347-355
4. Gupta, R., and Jentoft, N. (1992) J. Biol. Chem. 267, 3160-3167
5. Thornton, D. J., Davies, J. R., Kraayenbrink, M., Richardson, P. S., Sheehan, J. K., and Carlstedt, I. (1990) Biochem. J. 265, 179-186
6. Pigny, P., Guyonnet-Duperat, V., Hill, A. S., Pratt, W. S., Galiegue-Zouitina, S., D'Hooge, M. C., Laine, A., Van-Seuningen, I., Degand, P., Gum, J. R., Kim, Y. S., Swallow, D. M., Aubert, J. P., and Porchet, N. (1996) Genomics 38, 340-352
7. Perez-Vilar, J., and Hill, R. L. (1999) J. Biol. Chem. 274, 31751-31754
8. Perez-Vilar, J., Eckhardt, A. E., DeLuca, A., and Hill, R. L. (1998) J. Biol. Chem. 273, 14442-14449
9. Perez-Vilar, J., and Hill, R. L. (1998) J. Biol. Chem. 273, 34527-34534
10. Godl, K., Johansson, M. E. V., Lidell, M. E., Morgelin, M., Harlsson, H., Olson, F. J., Gom, J. R., Kim, Y. S., and Hansson, G. C. (2002) J. Biol. Chem. 277, 47248-47256
11. Axelsson, M. A. B., Asker, N., and Hansson, G. C. (1998) J. Biol. Chem. 273, 18862-18870
12. Herrmann, A., Davies, J. R., Lindell, G., Martensson, S., Packer, N. H., Swallow, D. M., and Carlstedt, I. (1999) J. Biol. Chem. 274, 15828-15836
13. Thornton, D. J., Gray, T., Nettesheim, P., Howard, M., Koo, J. S., and Sheehan, J. K. (2000) Am. J. Physiol. 278, L1118-L1128
14. Wickstrom, C., and Carlstedt, I. (2001) J. Biol. Chem. 276, 47116-47121
15. Sheehan, J. K., Howard, M., Richardson, P. S., Longwill, T., and Thornton, D. J. (1999) Biochem. J. 338, 507-513
16. Thornton, D. J., Carlstedt, I., Howard, M., Devine, P. L., Price, M. R., and Sheehan, J. K. (1996) Biochem. J. 316, 967-975
17. Kirkham, S., Sheehan, J. K., Knight, D., Richardson, P. S., and Thornton, D. J. (2002) Biochem. J. 361, 537-546
18. Sheehan, J. K., Brazeau, C., Kutay, S., Pigeon, H., Kirkham, S., Howard, M., and Thornton, D. J. (2000) Biochem. J. 347, 37-44
19. Aksoy, N., Thornton, D. J., Corfield, A., Paraskeva, C., and Sheehan, J. K. (1999) Glycobiology 9, 739-746
20. Saraste, J., Palade, G. E., and Farquhar, M. G. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 6425-6429
21. Wagner, D. D. (1990) Annu. Rev. Cell Biol. 6, 217-246.
22. Sadler, J. E. (1998) Annu. Rev. Biochem. 67, 395-424
23. Perez-Vilar, J., Eckhardt, A. E., and Hill, R. L. (1996) J. Biol. Chem. 271, 9845-9850
24. Bell, S. L., Xu, G., and Forstner, J. F. (2001) Biochem. J. 357, 203-209
25. Asker, N., Axelsson, M. A. B., Olofsson, S-V., and Hansson, G. C. (1998) J. Biol. Chem. 273, 18857-18863
26. Thornton, D. J., Davies, J. R., Carlstedt, I., and Sheehan, J. K. (1997) in Airway Mucus: Basic Mechanisms and Clinical Perspectives (Rogers, D. F., and Letham, M. I., eds) pp. 19-39, Birkhauser Verlag, Basel
27. Khatri, I. A., Forstner, G. G., and Forstner, J. F. (1998) Biochem. J. 331, 323-330
28. Gerken, T. A., Butenhof, K. J., and Shogren, R. (1989) Biochemistry 28, 5536-5543
29. Thornton, D. J., Holmes, D. F., Sheehan, J. K., and Carlstedt, I. (1989) Anal. Biochem. 182, 160-164